KEYGRAF 2 CAPSULE 10'S
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KEYGRAF 2 CAPSULE 10'S
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KEYGRAF 2 CAPSULE 10'S

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KEYGRAF 2 CAPSULE 10'S

By ANTHEM BIOPHARMA

MRP

944.45

₹755.56

20 % OFF

₹75.56 Only /

CAPSULE

10

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Composition

Product DetailsArrow

About KEYGRAF 2 CAPSULE 10'S

  • KEYGRAF 2 CAPSULE 10'S contains the active substance Tacrolimus. It functions as an immunosuppressant, belonging to a class of medications known as calcineurin inhibitors. This capsule is used in conjunction with other medications to prevent the rejection of organ transplants in individuals who have received liver, kidney, heart, or other organ transplants. Its primary function is to control the body's immune response, thus enabling the acceptance of the transplanted organ.
  • Before starting KEYGRAF 2 CAPSULE 10'S, it's crucial to inform your doctor about all existing medical conditions and allergies. Do not take this medicine if you have a known allergy to tacrolimus or any of its other ingredients. Additionally, disclose any allergies you may have to any group of antibiotics. It's essential to inform your doctor if you have a history of liver or heart disease before commencing treatment with this medication. Promptly notify your physician if you experience any concerning symptoms after taking this medicine, such as fever, unexplained bruising under the skin (which may manifest as red dots), unusual fatigue, confusion, yellowing of the skin or eyes, reduced urine output, vision disturbances, or seizures.
  • During treatment with KEYGRAF 2 CAPSULE 10'S, it is important to take precautions to minimize exposure to sunlight and UV light. Wear appropriate protective clothing and use sunscreen with a high sun protection factor. This is due to the potential risk of malignant skin changes associated with immunosuppressive therapy. This medicine may cause diarrhea; if you experience diarrhea for more than a day, inform your physician. If you require any vaccinations, consult your doctor before receiving them to ensure they are safe and appropriate while taking this medication. Regular monitoring and communication with your healthcare provider are essential to manage potential side effects and ensure the effectiveness of the treatment.

Uses of KEYGRAF 2 CAPSULE 10'S

  • Helps prevent the body from rejecting transplanted organs after transplant surgery, ensuring the body accepts the new organ.

Side Effects of KEYGRAF 2 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for KEYGRAF 2 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, KEYGRAF 2 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of KEYGRAF 2 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with KEYGRAF 2 CAPSULE 10'S, taking into account your specific medical condition, the severity of your symptoms, and other relevant factors. It is crucial to always take KEYGRAF 2 CAPSULE 10'S exactly as prescribed by your doctor to ensure its effectiveness and minimize potential side effects.
  • Do not attempt to open, break, crush, or chew the capsules. Doing so may alter the way the medication is absorbed and could affect its efficacy. Instead, swallow the capsule whole with a full glass of water to ensure it reaches your stomach intact.
  • For optimal absorption and effectiveness, take KEYGRAF 2 CAPSULE 10'S on an empty stomach. This means taking it either at least one hour before a meal or two to three hours after eating. This timing helps to avoid interference from food, which can sometimes reduce the amount of medication your body absorbs. Consistency in timing is key for the best results.
  • If you have any questions or concerns about how to take KEYGRAF 2 CAPSULE 10'S, don't hesitate to ask your doctor or pharmacist for clarification. They can provide personalized guidance based on your individual needs and medical history.

How to store KEYGRAF 2 CAPSULE 10'S?Arrow

  • Keep KEYGRAF 2MG CAP 1X10 away from the reach of children and pets.
  • Store KEYGRAF 2MG CAP 1X10 at room temperature.

Benefits of KEYGRAF 2 CAPSULE 10'SArrow

  • KEYGRAF 2 CAPSULE 10'S is a potent immunosuppressant medication that works by selectively suppressing the immune system. It achieves this by primarily targeting T-lymphocytes, crucial cells responsible for orchestrating immune responses. The capsule inhibits the activation and proliferation of these T-lymphocytes, effectively reducing their ability to trigger an immune reaction.
  • Furthermore, KEYGRAF 2 CAPSULE 10'S also interferes with the T-helper-cell-dependent B-cell response. B-cells are another type of immune cell responsible for producing antibodies. By disrupting the communication between T-helper cells and B-cells, the medication further dampens the immune response.
  • The mechanism of action involves binding to an intracellular protein known as FKBP-12. This binding results in the formation of a complex called tacrolimus-FKBP. This complex then inhibits calcineurin phosphatase, an enzyme vital for T-cell activation. By inhibiting calcineurin, the formation of new T cells is suppressed, leading to a reduction in the overall immune response. This targeted approach helps prevent the body from attacking transplanted organs or tissues in autoimmune diseases.

How to use KEYGRAF 2 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take KEYGRAF 2 CAPSULE 10'S exactly as prescribed by your doctor. Do not alter the capsule in any way; do not open, break, crush, or chew it.
  • For optimal absorption and effectiveness, swallow the capsule whole with a full glass of water. Consistency in timing is also important for best results.
  • To maximize the medication's impact, take these capsules on an empty stomach, ensuring that you take it either at least 1 hour before a meal or 2 to 3 hours after eating. This helps to avoid any potential food-drug interactions that could reduce its efficacy.
  • If you have any concerns about how to take this medication or experience any unusual side effects, contact your doctor immediately.

FAQs

What if I missed a dose of KEYGRAF 2 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with KEYGRAF 2 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take KEYGRAF 2 CAPSULE 10'S after a transplant?Arrow

The duration of KEYGRAF 2 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, KEYGRAF 2 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can KEYGRAF 2 CAPSULE 10'S increase the risk of infections?Arrow

Yes, KEYGRAF 2 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can KEYGRAF 2 CAPSULE 10'S affect kidney function?Arrow

KEYGRAF 2 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy

Should I follow any dietary restrictions while taking KEYGRAF 2 CAPSULE 10'S?Arrow

KEYGRAF 2 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important. 

What are the interactions of KEYGRAF 2 CAPSULE 10'S with other drugs?Arrow

NULL interaction of KEYGRAF 2 CAPSULE 10'S with other drungs

What advice should I follow while taking KEYGRAF 2 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using KEYGRAF 2 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly. 

What is KEYGRAF 2 CAPSULE 10'S made of?Arrow

TACROLIMUS is molecule/combination used for making KEYGRAF 2 CAPSULE 10'S.

For what ailments/diseases/conditions is KEYGRAF 2 CAPSULE 10'S prescribed?Arrow

KEYGRAF 2 CAPSULE 10'S is presecribed for ailments related to Nephrology.

Does KEYGRAF 2 CAPSULE 10'S help in treating infectious diseases?Arrow

KEYGRAF 2 CAPSULE 10'S may be used in the treatment of certain infectious diseases.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Very cheap, helpful, friendly service

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Reviewed on 10-02-2023

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Good experience with best medicine purchase at affordablee prices.

Aman Rohit M

Reviewed on 05-02-2024

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(5/5)

One stop solution for medicine

Chintan Joshi

Reviewed on 16-01-2024

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Very good customer approach

Ketan Sarkar

Reviewed on 20-01-2024

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(5/5)

Good

tarif Malek

Reviewed on 15-01-2024

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(5/5)


Marketer / Manufacturer Details

ANTHEM BIOPHARMA

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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