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TACROGRAF 2MG CAPSULE 10'S

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TACROGRAF 2MG CAPSULE 10'S

By BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

MRP

944

₹600

36.44 % OFF

₹60 Only /

CAPSULE

59

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Composition

Product DetailsArrow

About TACROGRAF 2MG CAPSULE 10'S

  • TACROGRAF 2MG CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. Tacrolimus works by suppressing the immune system, preventing it from attacking the transplanted organ.
  • It is crucial to adhere to your healthcare provider's instructions regarding dosage and administration of TACROGRAF 2MG CAPSULE 10'S. Regular blood tests are necessary to monitor tacrolimus levels in your body and adjust the dosage accordingly. Factors like kidney or liver function, other medications you are taking, and your overall health can influence the appropriate dosage. Consistent monitoring helps minimize the risk of side effects and ensures the medication's effectiveness.
  • Do not take TACROGRAF 2MG CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
  • Limit exposure to sunlight and UV light while consuming TACROGRAF 2MG CAPSULE 10'S by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them.

Uses of TACROGRAF 2MG CAPSULE 10'S

  • Prevent organ transplant rejections. TACROGRAF 2MG CAPSULE 10'S is used to prevent the transplanted organ from being rejected by the body.

How TACROGRAF 2MG CAPSULE 10'S Works

  • TACROGRAF 2MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
  • TACROGRAF 2MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, TACROGRAF 2MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, TACROGRAF 2MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of TACROGRAF 2MG CAPSULE 10'S in skin disorders is not fully understood.

Side Effects of TACROGRAF 2MG CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for TACROGRAF 2MG CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, TACROGRAF 2MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of TACROGRAF 2MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 2MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take TACROGRAF 2MG CAPSULE 10'S exactly as prescribed by your doctor. Deviating from the prescribed dosage or schedule can impact the effectiveness of the medication and potentially lead to adverse effects.
  • To ensure optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. Swallow the capsule whole with a full glass of water. TACROGRAF 2MG CAPSULE 10'S should be taken on an empty stomach, ideally at least 1 hour before a meal or 2 to 3 hours after eating. This timing helps minimize potential interactions with food that could affect how the medication is absorbed into your system.
  • If you have any questions or concerns regarding the dosage, timing, or any other aspect of your TACROGRAF 2MG CAPSULE 10'S treatment, do not hesitate to consult your doctor or pharmacist. They can provide personalized guidance and address any uncertainties you may have.

How to store TACROGRAF 2MG CAPSULE 10'S?Arrow

  • Keep TACROGRAF 2MG CAP 1X10 away from the reach of children and pets.
  • Store TACROGRAF 2MG CAP 1X10 at room temperature.

Benefits of TACROGRAF 2MG CAPSULE 10'SArrow

  • TACROGRAF 2MG CAPSULE 10'S is a powerful immunosuppressant medication that plays a crucial role in preventing organ rejection after transplantation. It achieves this by selectively suppressing the activity of T-lymphocytes, which are key players in the immune system's response to foreign substances like a transplanted organ. The medication works by binding to an intracellular protein known as FKBP-12. This binding action leads to the formation of a tacrolimus-FKBP complex.
  • This complex then inhibits calcineurin phosphatase, a critical enzyme involved in T-cell activation. By inhibiting calcineurin, TACROGRAF 2MG CAPSULE 10'S effectively blocks the signaling pathways necessary for T-cell proliferation and the subsequent immune response. This suppression is vital to prevent the body from attacking the transplanted organ.
  • Furthermore, TACROGRAF 2MG CAPSULE 10'S also impacts the activity of B-cells, another type of immune cell. It inhibits the T-helper-cell-dependent B-cell response, further dampening the overall immune response and reducing the risk of rejection. In essence, the medication acts as a targeted immunosuppressant, selectively reducing the activity of the immune system to protect the transplanted organ without completely compromising the body's ability to fight off infections.

How to use TACROGRAF 2MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 2MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to strictly adhere to your doctor's instructions regarding the use of this medication.
  • Always take TACROGRAF 2MG CAPSULE 10'S exactly as prescribed. Do not attempt to alter the form of the capsule by opening, breaking, crushing, or chewing it. The capsule should be swallowed whole with a full glass of water to ensure proper absorption and effectiveness.
  • For optimal results, take TACROGRAF 2MG CAPSULE 10'S on an empty stomach. This generally means consuming the capsule at least one hour before a meal or waiting for two to three hours after eating. This timing helps to minimize potential interactions with food that could affect how the medication is absorbed into your system.
  • Consistency in timing is essential for maintaining stable drug levels in your body. Try to take TACROGRAF 2MG CAPSULE 10'S at the same time(s) each day to maximize its therapeutic benefits and minimize the risk of side effects. If you have any questions or concerns about how to take this medication, do not hesitate to ask your doctor or pharmacist for clarification.

FAQs

What if I missed a dose of TACROGRAF 2MG CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with TACROGRAF 2MG CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take TACROGRAF 2MG CAPSULE 10'S after a transplant?Arrow

The duration of TACROGRAF 2MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, TACROGRAF 2MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can TACROGRAF 2MG CAPSULE 10'S increase the risk of infections?Arrow

Yes, TACROGRAF 2MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can TACROGRAF 2MG CAPSULE 10'S affect kidney function?Arrow

TACROGRAF 2MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy. 

Should I follow any dietary restrictions while taking TACROGRAF 2MG CAPSULE 10'S?Arrow

TACROGRAF 2MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

NULL interaction of TACROGRAF 2MG CAPSULE 10'S with other drungsArrow

Please consult your physician or pharmacist for information on how TACROGRAF 2MG CAPSULE 10'S interacts with other medications.

What advice should I follow while using TACROGRAF 2MG CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using TACROGRAF 2MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is TACROGRAF 2MG CAPSULE 10'S made of?Arrow

TACROLIMUS is molecule/combination used for making TACROGRAF 2MG CAPSULE 10'S.

For which Nephrology ailments/diseases/conditions TACROGRAF 2MG CAPSULE 10'S is prescribed?Arrow

TACROGRAF 2MG CAPSULE 10'S is used to treat nephrology ailments that require immunosuppression, such as preventing transplant rejection.

For which Infectious Disease TACROGRAF 2MG CAPSULE 10'S is prescribed?Arrow

TACROGRAF 2MG CAPSULE 10'S may be used to treat certain infectious diseases, particularly in cases where the immune system's response contributes to the disease.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Reviewed on 05-08-2023

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Marketer / Manufacturer Details

BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

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India

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TACROGRAF 2MG TAB 1X10 - 12804 - Medkart Pharmacy | Generic Medicines Online - Best Online Pharmacy App

TACROGRAF 2MG CAPSULE 10'S

MRP

944

₹600

36.44 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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