VINGRAF 2 CAPSULE 10'S
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VINGRAF 2 CAPSULE 10'S
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VINGRAF 2 CAPSULE 10'S

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VINGRAF 2 CAPSULE 10'S

By EMCURE PHARMACEUTICALS LIMITED

MRP

885.56

₹660

25.47 % OFF

₹66 Only /

CAPSULE

10

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About VINGRAF 2 CAPSULE 10'S

  • VINGRAF 2 CAPSULE 10'S contains the active substance Tacrolimus, an immunosuppressant belonging to the calcineurin inhibitor class. It's prescribed alongside other medications to prevent organ rejection in individuals who have undergone liver, kidney, heart, or other organ transplants. This medication works by controlling your body's immune response, allowing it to accept the transplanted organ and preventing it from attacking the new organ as a foreign object.
  • Before taking VINGRAF 2 CAPSULE 10'S, inform your doctor if you have any allergies, especially to tacrolimus or any of the other ingredients in the capsule. Also, report any allergies you have to any antibiotic groups. Disclose any pre-existing liver or heart conditions to your physician before starting treatment with this medication. It is important to inform your doctor about your complete medical history to ensure the safe and effective use of this medicine.
  • It is crucial to seek immediate medical attention if you experience any of the following symptoms after starting VINGRAF 2 CAPSULE 10'S: fever, unexplained bruising under the skin (appearing as red dots), unusual fatigue, confusion, yellowing of the skin or eyes (jaundice), reduced urine output, vision disturbances, or seizures. These could be signs of a serious adverse reaction and require prompt evaluation.
  • While taking VINGRAF 2 CAPSULE 10'S, minimize your exposure to sunlight and UV light by wearing protective clothing and using a sunscreen with a high SPF. Immunosuppressive therapy can increase the risk of skin cancer, so sun protection is essential. This medicine may also cause diarrhea. If you experience diarrhea that lasts for more than a day, inform your physician. Consult your doctor before receiving any vaccinations while taking this medication, as it can affect the effectiveness and safety of certain vaccines.
  • VINGRAF 2 CAPSULE 10'S is a potent medication that requires careful monitoring and adherence to your doctor's instructions. Regular follow-up appointments and blood tests are necessary to ensure the drug levels are within the therapeutic range and to monitor for any potential side effects. Do not adjust the dosage or stop taking the medication without consulting your doctor, as this could increase the risk of organ rejection.

Uses of VINGRAF 2 CAPSULE 10'S

  • Prevent organ transplant rejections. After an organ transplant, the body may attempt to reject the new organ. This medication helps to prevent this rejection process, allowing the transplanted organ to function properly.

Side Effects of VINGRAF 2 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for VINGRAF 2 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, VINGRAF 2 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of VINGRAF 2 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with VINGRAF 2 CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's prescription regarding the use of VINGRAF 2 CAPSULE 10'S.
  • To ensure optimal absorption and effectiveness, always take VINGRAF 2 CAPSULE 10'S exactly as directed. Avoid opening, breaking, crushing, or chewing the capsules, as this may alter the way the medication is released and absorbed into your system. Instead, swallow the capsule whole with a full glass of water.
  • For best results, take VINGRAF 2 CAPSULE 10'S on an empty stomach. This typically means taking it at least one hour before a meal or waiting two to three hours after eating before taking the capsule. Following these guidelines can help maximize the medication's benefits and minimize potential interactions with food. Consistency in timing is key to maintaining stable drug levels in your body and achieving the desired therapeutic outcome.
  • If you have any questions or concerns about how to take VINGRAF 2 CAPSULE 10'S, don't hesitate to ask your doctor or pharmacist for clarification. They can provide personalized instructions and address any individual needs you may have.

How to store VINGRAF 2 CAPSULE 10'S?Arrow

  • Keep VINGRAF 2MG CAP 1X10 away from the reach of children and pets.
  • Store VINGRAF 2MG CAP 1X10 at room temperature.

Benefits of VINGRAF 2 CAPSULE 10'SArrow

  • VINGRAF 2 CAPSULE 10'S is an immunosuppressant medication that works by diminishing the activity of your immune system. The medication achieves this by targeting specific immune cells, namely T-lymphocytes. VINGRAF 2 CAPSULE 10'S inhibits their activation and proliferation. It also affects the T-helper-cell-dependent B-cell response, another crucial component of the immune system.
  • VINGRAF 2 CAPSULE 10'S functions by binding to an intracellular protein known as FKBP-12, creating a complex called tacrolimus-FKBP. This complex then impedes the function of calcineurin phosphatase, an enzyme essential for T-cell activation. By inhibiting calcineurin phosphatase, VINGRAF 2 CAPSULE 10'S effectively curtails the formation of T cells, leading to a suppression of the overall immune response. This makes it valuable in preventing organ rejection after transplantation and in managing certain autoimmune disorders.
  • Essentially, VINGRAF 2 CAPSULE 10'S selectively weakens the immune system to prevent it from attacking transplanted organs or causing excessive inflammation in autoimmune conditions, thereby safeguarding the health and well-being of the patient. The targeted approach minimizes broad suppression, reducing the risk of widespread side effects while maintaining therapeutic efficacy.

How to use VINGRAF 2 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with VINGRAF 2 CAPSULE 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to always take VINGRAF 2 CAPSULE 10'S exactly as prescribed by your doctor. This ensures the medication works effectively and minimizes the risk of potential side effects.
  • Do not attempt to open, break, crush, or chew the capsules. These capsules are designed to be swallowed whole to ensure the medication is released properly within your body. Altering the capsule can affect the drug's absorption and efficacy.
  • Swallow the capsule whole with a full glass of water. This helps the capsule go down smoothly and ensures it reaches your stomach where it can be properly dissolved and absorbed.
  • For optimal absorption, take these capsules on an empty stomach, either at least 1 hour before a meal or 2 to 3 hours after eating. Food can interfere with the absorption of the medication, reducing its effectiveness. Following these guidelines will help maximize the benefits of VINGRAF 2 CAPSULE 10'S.

FAQs

What if I missed a dose of VINGRAF 2 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with VINGRAF 2 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take VINGRAF 2 CAPSULE 10'S after a transplant?Arrow

The duration of VINGRAF 2 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, VINGRAF 2 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can VINGRAF 2 CAPSULE 10'S increase the risk of infections?Arrow

Yes, VINGRAF 2 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can VINGRAF 2 CAPSULE 10'S affect kidney function?Arrow

VINGRAF 2 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking VINGRAF 2 CAPSULE 10'S?Arrow

VINGRAF 2 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important. 

NULL interaction of VINGRAF 2 CAPSULE 10'S with other drungsArrow

Interaction of VINGRAF 2 CAPSULE 10'S with other drugs are unknown.

What should I be advised when using VINGRAF 2 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using VINGRAF 2 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly. 

What is TACROLIMUS and how does it relate to VINGRAF 2 CAPSULE 10'S?Arrow

TACROLIMUS is a molecule/combination used for making VINGRAF 2 CAPSULE 10'S. It is an immunosuppressant that helps prevent organ rejection after transplantation.

For which Nephrology related conditions is VINGRAF 2 CAPSULE 10'S used?Arrow

VINGRAF 2 CAPSULE 10'S is primarily used in Nephrology to prevent organ rejection following kidney transplantation.

Can VINGRAF 2 CAPSULE 10'S help in treating Infectious Diseases?Arrow

While VINGRAF 2 CAPSULE 10'S is primarily an immunosuppressant, it may be used in some cases for managing certain specific infectious diseases, especially in transplant recipients.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Book Icon

Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

Tarif / Service is good

Venkataramanamurty Inguva

Reviewed on 15-07-2023

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(5/5)

Generic medicines available at low cost

nitin kanwe

Reviewed on 09-07-2023

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(5/5)

Good for generic medicine, quality medicine with affordable rate

nitesh vekariya

Reviewed on 03-02-2024

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(5/5)

Awesome experience every time i get medicine on time and they have delivery on time also staff are very cooperative and knowledgeable

Tarun Ezava

Reviewed on 22-06-2023

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(5/5)

Genuine products

monalisha satapathy

Reviewed on 05-08-2023

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(5/5)


Marketer / Manufacturer Details

EMCURE PHARMACEUTICALS LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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