KNILONAT 150 CAPSULE 10'S
Prescription Required

Prescription Required

KNILONAT 150 CAPSULE 10'S
Medkart reliability icon

Authentic Product

India's Leading Generic Pharmacy

India's Leading Generic Pharmacy

Secure Payment

Secure Payment

KNILONAT 150 CAPSULE 10'S

Share icon

KNILONAT 150 CAPSULE 10'S

By NATCO PHARMA LIMITED

MRP

835

₹668

20 % OFF

₹66.8 Only /

CAPSULE

10

People Bought in last month

Location icon

Check Delivery

or
Arrives in:

--


Medicine Composition Icon

Composition

Product DetailsArrow

About KNILONAT 150 CAPSULE 10'S

  • KNILONAT 150 CAPSULE 10'S is an antineoplastic drug containing Nilotinib as its active ingredient. It belongs to a class of medications known as tyrosine kinase inhibitors. This medication is prescribed for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a type of blood cancer characterized by the abnormal production of white blood cells. In both adult and pediatric patients, it is used for newly diagnosed Chronic Myeloid Leukemia (CML) and for those who have experienced adverse effects from previous treatments. Furthermore, it is also indicated for patients who no longer respond to prior therapies, including Imatinib.
  • Before taking KNILONAT 150 CAPSULE 10'S, inform your healthcare provider if you have any known allergies to Nilotinib or any other components of the medication. Disclose any history of heart conditions, such as heart attacks or abnormal electrical signals, chest pain, brain stroke, or claudication (reduced blood flow in the leg). Notify your doctor if you have any liver or pancreas disorders or if you are experiencing a deficiency in potassium or magnesium. It's crucial to inform your doctor about all medications you are currently taking, particularly those aimed at lowering blood cholesterol. Also, reveal any underlying health conditions, especially if you have or have had a hepatitis B infection, as this medicine can reactivate HPV, potentially leading to fatal consequences in some cases. Avoid consuming grapefruit or grapefruit juice while taking this medication. If you have any sugar intolerances, inform your doctor, as this medicine contains lactose.
  • During the course of treatment with KNILONAT 150 CAPSULE 10'S, your doctor will conduct regular blood tests to monitor liver and pancreas function, as well as blood cell counts (white blood cells, red blood cells, and platelets). These tests are also performed to monitor heart condition (QT interval prolongation), electrolyte levels, and sugar and fat levels to assess how well you are tolerating the medication. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is essential to use effective birth control methods during treatment with this medication. This medicine is potent and needs to be taken under strict medical supervision. Regular follow-ups with your doctor are crucial to monitor your progress and adjust the treatment plan if needed. Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can also support your overall well-being during treatment.
  • If you experience any unusual symptoms or side effects while taking KNILONAT 150 CAPSULE 10'S, promptly inform your healthcare provider. Common side effects may include nausea, fatigue, rash, and headache, but more serious side effects can occur. Do not stop taking the medication without consulting your doctor, as abrupt cessation can lead to complications. Your doctor will provide guidance on how to manage any side effects and ensure the safe and effective use of KNILONAT 150 CAPSULE 10'S.

Uses of KNILONAT 150 CAPSULE 10'S

  • Treatment of blood cancer, specifically Philadelphia chromosome-positive chronic myeloid leukemia, in both adult and pediatric patients.

Side Effects of KNILONAT 150 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects include sudden weight gain, swelling in hands, feet, ankles, or face, chest pain, blood pressure changes (high and low), discoloration of tongue, lips, or skin (blue), abnormal heartbeat (irregular heartbeat), hair loss, vision problems, stomach pain, vomiting of blood, blood in stools, yellowing of the skin, eyes, and dark urine, high blood sugar levels, and sensitivity to light. Common side effects include nausea, vomiting, diarrhoea, headache, muscle pain, stomach pain, hair loss, tiredness, constipation, slowing growth in children, pneumonia, loss of appetite, sleeplessness, depression, anxiety, stomach discomforts like bloating and flatulence after meals, and musculoskeletal pain.

  • Sudden weight gain
  • Swelling in hands, feet, ankles, or face
  • Chest pain
  • Blood pressure (high and low)
  • Discoloration of tongue, lips, or skin (blue)
  • Abnormal heart (irregular heartbeat)
  • Hair loss
  • Vision problem
  • Stomach pain, vomiting of blood, blood in stools.
  • Yellowing of the skin, eyes, and dark urine.
  • High blood sugar levels.
  • Sensitivity to light
  • Nausea, vomiting, diarrhoea.
  • Headache, muscle pain, stomach pain.
  • Hair loss.
  • Tiredness.
  • Constipation.
  • Slowing growth in children.
  • Pneumonia.
  • Loss of appetite.
  • Sleeplessness, depression, and anxiety.
  • Stomach discomforts like bloating and flatulence after meals.
  • musculoskeletal pain

Safety Advice for KNILONAT 150 CAPSULE 10'SArrow

default alt

Pregnancy

UNSAFE

KNILONAT 150 CAPSULE 10'S is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.

Dosage of KNILONAT 150 CAPSULE 10'SArrow

  • Always follow your doctor's instructions when taking KNILONAT 150 CAPSULE 10'S. This medication is designed to be swallowed whole with a glass of water. Avoid crushing, chewing, or breaking the capsule, as this could affect how the medicine is absorbed in your body. Your healthcare provider will determine the appropriate dosage and treatment duration based on your specific needs, taking into account factors like your age, weight, and the nature of your condition.
  • It's crucial to adhere to the prescribed dosage and schedule. Do not alter the dosage or discontinue the medication without first consulting your doctor. Stopping KNILONAT 150 CAPSULE 10'S abruptly can lead to unwanted side effects or a return of your symptoms. If you have any concerns or experience any adverse reactions, reach out to your doctor for guidance.

How to store KNILONAT 150 CAPSULE 10'S?Arrow

  • Keep KNILONAT 150MG CAP 1X10 away from the reach of children and pets.
  • Store KNILONAT 150MG CAP 1X10 at room temperature.

Benefits of KNILONAT 150 CAPSULE 10'SArrow

  • In Chronic Myelogenous Leukemia (CML), the BCR-ABL tyrosine kinase enzyme fuels the rapid and uncontrolled division of cells. KNILONAT 150 CAPSULE 10'S precisely targets this enzyme to restore balance. By disrupting the abnormal signaling pathway triggered by BCR-ABL, this medication effectively inhibits the growth and spread of cancerous cells. It acts as a targeted therapy, focusing specifically on the root cause of the uncontrolled cell proliferation in CML.
  • KNILONAT 150 CAPSULE 10'S works by selectively binding to the BCR-ABL protein, preventing it from activating the downstream signaling pathways that drive cancer cell growth. This targeted approach minimizes damage to healthy cells, reducing the risk of side effects compared to traditional chemotherapy. This focused action helps to control the disease and improve overall patient outcomes.
  • This medication plays a vital role in managing CML by directly interfering with the abnormal protein responsible for its progression. Through targeted inhibition of the BCR-ABL kinase, it helps to normalize cell growth and prevent the spread of cancerous cells, ultimately contributing to improved disease control and patient well-being. Regular monitoring and adherence to the prescribed treatment plan are crucial for optimal results.

How to use KNILONAT 150 CAPSULE 10'SArrow

  • Take KNILONAT 150 CAPSULE 10'S exactly as your doctor prescribes. This medication is intended for oral administration, so swallow it whole with a full glass of water. Avoid crushing, chewing, or breaking the capsule, as this could affect how the medicine is absorbed in your body. Your healthcare provider will determine the most appropriate dosage and treatment duration specifically tailored to your individual needs. This decision will be based on factors such as your age, body weight, overall health status, and the specific condition being treated.
  • It is crucial to adhere to your doctor's instructions regarding the use of KNILONAT 150 CAPSULE 10'S. Do not alter the dosage or frequency of administration without consulting your physician. Consistent and correct usage will help maximize the therapeutic benefits of the medication. If you have any questions or concerns about how to take this medication, don't hesitate to ask your doctor or pharmacist for clarification. They can provide you with detailed instructions and address any uncertainties you may have. It is also important not to discontinue the medicine abruptly without your doctor's approval. Stopping the medication prematurely may lead to a worsening of your condition or the recurrence of symptoms.
  • Remember, this medicine is prescribed for your specific condition, and it's not meant to be shared with others. Self-treating or giving your medication to someone else can be harmful, even if they have similar symptoms. Always consult a healthcare professional for personalized medical advice and treatment options.

FAQs

Can KNILONAT 150 CAPSULE 10'S cause liver damage?Arrow

KNILONAT 150 CAPSULE 10'S may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking KNILONAT 150 CAPSULE 10'S. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

How does KNILONAT 150 CAPSULE 10'S differ from other medications used to treat chronic myeloid leukemia, such as Imatinib?Arrow

Imatinib, in its selectivity and potency. KNILONAT 150 CAPSULE 10'S is more selective for the BCR-ABL protein that drives the growth of cancer cells, and it is more potent in inhibiting the activity of this protein. KNILONAT 150 CAPSULE 10'S has also been shown to be effective in patients who have developed resistance to Imatinib

What are the potential long-term effects of KNILONAT 150 CAPSULE 10'S on the body?Arrow

The potential long-term effects of KNILONAT 150 CAPSULE 10'S on the body include cardiovascular events, such as hypertension, arrhythmias, and heart failure, as well as liver dysfunction, pancreatic enzyme elevation, and fluid retention. These side effects are generally rare, but they can occur in some patients.

How to monitor the effects of KNILONAT 150 CAPSULE 10'S over the course of treatment?Arrow

It is monitored through regular blood tests, electrocardiograms, and imaging studies. Blood tests can assess liver and kidney function, blood counts, and electrolyte levels. ECG can detect any changes in heart rhythm or function. Imaging studies, such as echocardiograms and chest X-rays, can evaluate the heart and lungs for any signs of damage or fluid accumulation.

Who should not take KNILONAT 150 CAPSULE 10'S?Arrow

KNILONAT 150 CAPSULE 10'S should not be taken by pregnant or breastfeeding women, or by people with certain medical conditions such as severe liver or kidney disease, a history of pancreatitis, or a prolonged QT interval.

NULL interaction of KNILONAT 150 CAPSULE 10'S with other drungsArrow

There is no known interaction of KNILONAT 150 CAPSULE 10'S with other drugs.

What is the advice related to KNILONAT 150 CAPSULE 10'S?Arrow

Based on your condition your doctor may prescribe a lower dose. KNILONAT 150 CAPSULE 10'S can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.

Which molecule/combination is used for making KNILONAT 150 CAPSULE 10'S?Arrow

NILOTINIB is molecule/combination used for making KNILONAT 150 CAPSULE 10'S.

For which ailments/diseases/conditions KNILONAT 150 CAPSULE 10'S is prescribed?Arrow

KNILONAT 150 CAPSULE 10'S is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo; Tyrosine Kinase Inhibitors

default alt
Book Icon

Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium (EMC)

default alt
Book Icon

Novartis, US Food & Drug Administration

default alt

Ratings & Review

Awesome

Pankaj Patel

Reviewed on 13-06-2023

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)

Excellent service and support 24/7 Supportive and co operative staff.

Ajay Nayak Dhadkan

Reviewed on 13-01-2024

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)

Super service

rensom christy

Reviewed on 06-01-2023

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)

Very good service and discount

Yatin Patel

Reviewed on 13-01-2024

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)

Good place to buy generic medicines

Patel Jinal

Reviewed on 24-05-2023

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)


Marketer / Manufacturer Details

NATCO PHARMA LIMITED

Country of Origin -

India

report-us

Issue with Content?

Report Us

Alternatives

Customer Also Bought

KNILONAT 150 CAPSULE 10'S

KNILONAT 150 CAPSULE 10'S

MRP

835

₹668

20 % OFF

Download medkart app

Download Our App!

Get exclusive app only offers on our mobile application

Download from Google playDownload from App Store

Quick Links

default alt
default alt
default alt
default alt
default alt
default alt
default alt
default alt
default alt
default alt

Related Blogs

default alt

Balanitis Treatment: Medications, Antibiotics, and Creams

Cure inflammation of the glans penis with effective balanitis treatment. Discover best antibiotics, creams, and medications for relief.

Read More

default alt

Best Creams for fungal infection in private area - Buy Cream Online

Wondering which are the Best Creams for fungal infection in private area? Buy Fungal Infection Creams Online at affordable range.

Read More

default alt

How to Identify Generic Medicine? Find Generic Medicine

How to Identify Generic Medicine? Know in detail how to find generic medicine? Also, check how to find generic medicine for branded medicine.

Read More

default alt

High ESR Treatment: Causes and Effective Treatment Options

Learn about erythrocyte sedimentation rate (ESR), its normal range, high ESR symptoms, causes, and treatment. Understand the importance of ESR blood tests and management of ESR levels.

Read More

default alt

How to Increase Breast Size Naturally? - Breast Size Increase

Discover effective ways to naturally enhance your breast size. Explore top methods and exercises to increase breast size.

Read More

default alt

Ayurvedic Medicine for HIV: Ayurvedic Treatment for HIV

Ayurvedic Medicine for HIV: Know if there is any Ayurvedic treatment available for HIV? Know ayurvedic treatment for hiv in Detail,.

Read More

default alt

MD का फुल फॉर्म मेडिकल में फॉर्म क्या है? MD Full Form in Hindi

मेडिकल में MD का पूरा नाम डॉक्टर ऑफ मेडिसिन है। जानें MD फुल फॉर्म मेडिकल शब्दावली में। अधिक जानकारी के लिए पढ़ें।

Read More

default alt

Normal Blood Sugar Levels Chart: Sugar Level Chart

Normal Blood Sugar Levels Chart: Discover the ideal blood sugar levels by age and gain a detailed understanding of the Sugar Level Chart

Read More

default alt

टाइफाइड का इलाज: दवा, सावधानी, और उपाय - सम्पूर्ण जानकारी

Typhoid Treatment in Hindi - टाइफाइड बुखार साल्मोनेला टाइफी जीवाणु के कारण होता है। जाँचें टाइफाइड बुखार का इलाज क्या है?

Read More

default alt

Fascinating Benefits and Uses of Basil Seeds - Medkart Pharmacy Blogs

Amazing Benefits of Basil Seeds, from boosting digestion to improving skin health. Learn how to use them in your diet for maximum wellness.

Read More

Disclaimer

Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

India's most trusted generic medicine pharmacy.

10 Lakh+

Happy customers

35000+

Pin-codes Covered

75 Lakh+

Orders Delivered

WHO GMP Logo

Authentic Products

All WHO-GMP Certified Medicines

About Medkart Pharmacy

Our Services

Browse by

Policies

Download the app for free

Download from Google playDownload from App Store

©2025 Medkart Pharmacy. All Rights Reserved