NELOVA 150MG CAPSULE 28'S
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NELOVA 150MG CAPSULE 28'S
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NELOVA 150MG CAPSULE 28'S

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NELOVA 150MG CAPSULE 28'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

1950

₹1657.5

15 % OFF

₹59.2 Only /

CAPSULE

10

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Composition

Product DetailsArrow

About NELOVA 150MG CAPSULE 28'S

  • NELOVA 150MG CAPSULE 28'S is an antineoplastic drug containing Nilotinib as its active ingredient. It belongs to a class of medications called tyrosine kinase inhibitors. This medicine is prescribed to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a type of blood cancer characterized by the overproduction of white blood cells. In both adult and pediatric patients, it is used as a first-line treatment for newly diagnosed Chronic Myeloid Leukemia (CML) and for patients who have experienced adverse effects from previous therapies. Furthermore, it is indicated for patients who no longer respond to prior treatments, including Imatinib. This medication works by targeting specific proteins within the leukemia cells, thereby inhibiting their growth and spread. It is a crucial part of managing CML and improving patient outcomes.
  • Before taking NELOVA 150MG CAPSULE 28'S, inform your doctor if you have any allergies to Nilotinib or any other components of the medicine. Disclose any past or present heart conditions such as heart attacks, irregular heart rhythms, chest pain, stroke, or claudication (reduced blood flow to the legs). Report any liver or pancreas disorders, or any deficiencies in potassium or magnesium levels. It's essential to inform your doctor about all medications you are currently taking, especially those intended to lower blood cholesterol. Also, disclose any history of hepatitis B infection, as this medicine can reactivate the virus, potentially leading to severe complications. Avoid consuming grapefruit or grapefruit juice during treatment. If you have any sugar intolerances, inform your doctor, as this medicine contains lactose. Regular monitoring and open communication with your healthcare provider are essential for safe and effective treatment.
  • During the course of treatment with NELOVA 150MG CAPSULE 28'S, your doctor will regularly conduct blood tests to monitor liver and pancreas function, blood cell counts (white blood cells, red blood cells, and platelets), heart health (QT interval prolongation), electrolyte levels, and sugar and fat levels to assess how well you are tolerating the medication. It is critical to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Effective contraception is necessary during treatment with this medicine to prevent potential harm to the fetus. Regular check-ups and prompt reporting of any unusual symptoms or side effects are crucial to ensure optimal management and safety throughout your treatment journey.

Uses of NELOVA 150MG CAPSULE 28'S

  • Treatment of blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and children.

Side Effects of NELOVA 150MG CAPSULE 28'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. NELOVA 150MG CAPSULE 28'S can cause both serious and common side effects.

  • Sudden weight gain
  • Swelling in hands, feet, ankles, or face
  • Chest pain
  • Blood pressure (high and low)
  • Discoloration of tongue, lips, or skin (blue)
  • Abnormal heart (irregular heartbeat)
  • Hair loss
  • Vision problem
  • Stomach pain, vomiting of blood, blood in stools.
  • Yellowing of the skin, eyes, and dark urine.
  • High blood sugar levels.
  • Sensitivity to light
  • Nausea, vomiting, diarrhoea.
  • Headache, muscle pain, stomach pain.
  • Hair loss.
  • Tiredness.
  • Constipation.
  • Slowing of growth in children.
  • Pneumonia.
  • Loss of appetite.
  • Sleeplessness, depression, and anxiety.
  • Stomach discomforts like bloating and flatulence after meals.
  • musculoskeletal pain

Safety Advice for NELOVA 150MG CAPSULE 28'SArrow

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Pregnancy

UNSAFE

NELOVA 150MG CAPSULE 28'S is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.

Dosage of NELOVA 150MG CAPSULE 28'SArrow

  • Always adhere to your doctor's instructions when taking NELOVA 150MG CAPSULE 28'S. This medication is designed to be swallowed whole with a full glass of water. It's crucial that you do not crush, chew, or attempt to open the capsule, as this could affect how the medication is absorbed and its effectiveness.
  • The precise dosage and the length of time you need to take NELOVA 150MG CAPSULE 28'S will be determined by your doctor. They will take into account several factors, including your age, body weight, and the specific health condition being treated. It's essential to follow their guidance closely to achieve the best possible results from the treatment.
  • Consistency is key when taking NELOVA 150MG CAPSULE 28'S. Try to take it at the same time each day to help you remember and to maintain a steady level of medication in your body. If you have any questions or concerns about how to take NELOVA 150MG CAPSULE 28'S, don't hesitate to ask your doctor or pharmacist for clarification.
  • It's important not to stop taking NELOVA 150MG CAPSULE 28'S prematurely, even if you start to feel better. Continue taking the medication for the full duration prescribed by your doctor. Stopping the medication too soon could lead to a return of your symptoms or other complications. Only discontinue use if your doctor specifically advises you to do so.

How to store NELOVA 150MG CAPSULE 28'S?Arrow

  • Keep NELOVA 150MG CAP 1X28 away from the reach of children and pets.
  • Store NELOVA 150MG CAP 1X28 at room temperature.

Benefits of NELOVA 150MG CAPSULE 28'SArrow

  • NELOVA 150MG CAPSULE 28'S is a targeted therapy specifically designed to combat Chronic Myelogenous Leukemia (CML). CML is characterized by the uncontrolled proliferation of cells due to the presence of an abnormal tyrosine kinase called BCR-ABL. This tyrosine kinase constantly signals the cells to divide and multiply, leading to the overproduction of white blood cells that are characteristic of CML.
  • NELOVA 150MG CAPSULE 28'S works by selectively inhibiting the BCR-ABL tyrosine kinase. By disrupting the signaling pathway of this enzyme, NELOVA 150MG CAPSULE 28'S effectively halts the uncontrolled growth and spread of cancer cells. This targeted approach minimizes damage to healthy cells, reducing side effects compared to traditional chemotherapy.
  • The medication binds directly to the BCR-ABL protein, preventing it from sending signals that promote cell growth. This action helps to restore normal blood cell production and reduces the number of leukemia cells in the body. The primary goal of treatment with NELOVA 150MG CAPSULE 28'S is to achieve and maintain remission, where the signs and symptoms of CML are minimized or eliminated, improving the patient's quality of life.

How to use NELOVA 150MG CAPSULE 28'SArrow

  • Take NELOVA 150MG CAPSULE 28'S exactly as your doctor instructs. Adhere to the prescribed dosage and schedule for optimal results. Typically, it is recommended to swallow the capsule whole with a full glass of water. Avoid crushing, chewing, or breaking the capsule, as this may affect how the medication is absorbed in your body. It's crucial to maintain consistency by taking it at the same time each day.
  • The dosage and duration of treatment will be determined by your doctor, considering factors such as your age, body weight, and the specific medical condition being treated. It is essential to follow your doctor's instructions precisely and complete the entire course of treatment, even if you start feeling better.
  • Do not discontinue taking NELOVA 150MG CAPSULE 28'S without consulting your doctor first. Abruptly stopping the medication may lead to a worsening of your condition or the occurrence of withdrawal symptoms. If you have any questions or concerns about how to take NELOVA 150MG CAPSULE 28'S, or if you experience any side effects, consult with your doctor or pharmacist for further guidance.

FAQs

Can NELOVA 150MG CAPSULE 28'S cause liver damage?Arrow

NELOVA 150MG CAPSULE 28'S may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking NELOVA 150MG CAPSULE 28'S. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

How does NELOVA 150MG CAPSULE 28'S differ from other medications used to treat chronic myeloid leukemia, such as Imatinib?Arrow

Imatinib, in its selectivity and potency. NELOVA 150MG CAPSULE 28'S is more selective for the BCR-ABL protein that drives the growth of cancer cells, and it is more potent in inhibiting the activity of this protein. NELOVA 150MG CAPSULE 28'S has also been shown to be effective in patients who have developed resistance to Imatinib.

What are the potential long-term effects of NELOVA 150MG CAPSULE 28'S on the body?Arrow

The potential long-term effects of NELOVA 150MG CAPSULE 28'S on the body include cardiovascular events, such as hypertension, arrhythmias, and heart failure, as well as liver dysfunction, pancreatic enzyme elevation, and fluid retention. These side effects are generally rare, but they can occur in some patients.

How to monitor the effects of NELOVA 150MG CAPSULE 28'S over the course of treatment?Arrow

It is monitored through regular blood tests, electrocardiograms, and imaging studies. Blood tests can assess liver and kidney function, blood counts, and electrolyte levels. ECG can detect any changes in heart rhythm or function. Imaging studies, such as echocardiograms and chest X-rays, can evaluate the heart and lungs for any signs of damage or fluid accumulation.

Who should not take NELOVA 150MG CAPSULE 28'S?Arrow

NELOVA 150MG CAPSULE 28'S should not be taken by pregnant or breastfeeding women, or by people with certain medical conditions such as severe liver or kidney disease, a history of pancreatitis, or a prolonged QT interval.

NULL interaction of NELOVA 150MG CAPSULE 28'S with other drungsArrow

There are no known interactions between NELOVA 150MG CAPSULE 28'S and other drugs.

What is the advice related to NELOVA 150MG CAPSULE 28'S?Arrow

Based on your condition your doctor may prescribe a lower dose. NELOVA 150MG CAPSULE 28'S can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.

What molecule/combination is used for making NELOVA 150MG CAPSULE 28'S?Arrow

NILOTINIB is molecule/combination used for making NELOVA 150MG CAPSULE 28'S.

For what ailments/diseases/conditions is NELOVA 150MG CAPSULE 28'S prescribed?Arrow

NELOVA 150MG CAPSULE 28'S is prescribed for Oncology.

References

Book Icon

Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo; Tyrosine Kinase Inhibitors

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Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium (EMC)

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Novartis, US Food & Drug Administration

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(5/5)


Marketer / Manufacturer Details

SUN PHARMACEUTICAL INDUSTRIES LTD

Country of Origin -

India

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MRP

1950

₹1657.5

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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