NILOSURE 150 CAPSULE 4'S
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NILOSURE 150 CAPSULE 4'S
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NILOSURE 150 CAPSULE 4'S

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NILOSURE 150 CAPSULE 4'S

By BDR PHARMACEUTICALS INTERNATIONALS PVT LTD

MRP

387

₹328.95

15 % OFF

₹82.24 Only /

CAPSULE

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Composition

Product DetailsArrow

About NILOSURE 150 CAPSULE 4'S

  • NILOSURE 150 CAPSULE 4'S contains Nilotinib as an active ingredient and belongs to a class of medications known as tyrosine kinase inhibitors. It is prescribed for treating Philadelphia chromosome-positive chronic myeloid leukemia (Ph-positive CML), a specific type of leukemia characterized by the overproduction of white blood cells. This medication is suitable for both adult and pediatric patients who are newly diagnosed with CML, those who have experienced adverse effects from previous treatments, or those who no longer respond to previous treatments, including Imatinib. It functions by targeting and inhibiting the tyrosine kinase enzyme, which is crucial for the growth and spread of CML cells.
  • Before taking NILOSURE 150 CAPSULE 4'S, inform your doctor if you have a known allergy to Nilotinib or any other ingredients in the medicine. Disclose any history of heart conditions, such as heart attacks, abnormal electric signals, chest pain, brain stroke, or claudication (reduced blood flow in the leg). Also, inform your healthcare provider if you have liver or pancreas disorders, or electrolyte imbalances like low potassium or magnesium levels. It's important to discuss all current medications, particularly those aimed at lowering blood cholesterol. If you have or have had a hepatitis B infection, inform your doctor, as NILOSURE 150 CAPSULE 4'S can reactivate the virus, potentially leading to severe consequences. Avoid consuming grapefruit or grapefruit juice during treatment. Since this medicine contains lactose, inform your doctor if you have any sugar intolerances.
  • During treatment with NILOSURE 150 CAPSULE 4'S, regular blood tests will be necessary to monitor liver and pancreas function, blood cell counts (WBC, RBC, platelets), heart condition (QT interval prolongation), electrolyte levels, and sugar and fat levels to assess how well the medicine is tolerated. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is essential to use effective birth control methods during treatment. This medicine carries a risk of affecting fertility in both men and women, so discuss fertility preservation options with your doctor before starting the treatment. If you experience any side effects, consult your doctor immediately to get appropriate medical care and guidance.
  • Additionally, remember to maintain a healthy lifestyle during treatment. Follow a balanced diet, engage in regular exercise as advised by your healthcare provider, and avoid smoking and excessive alcohol consumption, as these can interfere with the effectiveness of the medication and overall health.

Uses of NILOSURE 150 CAPSULE 4'S

  • Treatment of blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adult and pediatric patients.

Side Effects of NILOSURE 150 CAPSULE 4'SArrow

Side effects are unwanted symptoms caused by medicines; however, not everyone experiences them. NILOSURE 150 CAPSULE 4'S can cause both serious and common side effects.

  • Sudden weight gain
  • Swelling in hands, feet, ankles, or face
  • Chest pain
  • Blood pressure (high and low)
  • Discoloration of tongue, lips, or skin (blue)
  • Abnormal heart (irregular heartbeat)
  • Hair loss
  • Vision problem
  • Stomach pain, vomiting of blood, blood in stools.
  • Yellowing of the skin, eyes, and dark urine.
  • High blood sugar levels.
  • Sensitivity to light
  • Nausea, vomiting, diarrhoea.
  • Headache, muscle pain, stomach pain.
  • Hair loss.
  • Tiredness.
  • Constipation.
  • Slowing of growth in children.
  • Pneumonia.
  • Loss of appetite.
  • Sleeplessness, depression, and anxiety.
  • Stomach discomforts like bloating and flatulence after meals.
  • musculoskeletal pain

Safety Advice for NILOSURE 150 CAPSULE 4'SArrow

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Pregnancy

UNSAFE

NILOSURE 150 CAPSULE 4'S is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.

Dosage of NILOSURE 150 CAPSULE 4'SArrow

  • Take NILOSURE 150 CAPSULE 4'S exactly as your doctor prescribes. It is crucial to adhere to their instructions for the best possible outcome. Typically, you should swallow the capsule whole with a full glass of water. Avoid crushing, chewing, or breaking the capsule, as this could affect how the medication is absorbed in your body. The dosage and duration of treatment will be determined by your doctor, taking into account factors such as your age, body weight, and the specific condition being treated. It's essential to follow their recommendations precisely.
  • Do not discontinue taking NILOSURE 150 CAPSULE 4'S without first consulting your doctor. Even if you start to feel better, it's important to complete the full course of treatment as prescribed. Stopping the medication prematurely could lead to a recurrence of the infection or the development of antibiotic resistance. If you have any concerns or experience any side effects while taking NILOSURE 150 CAPSULE 4'S, be sure to discuss them with your doctor.
  • For optimal results, maintain a consistent schedule for taking NILOSURE 150 CAPSULE 4'S. Try to take it at the same time each day to ensure a steady level of the medication in your system. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store NILOSURE 150 CAPSULE 4'S?Arrow

  • Keep NILOSURE 150MG CAP 1X4 away from the reach of children and pets.
  • Store NILOSURE 150MG CAP 1X4 at room temperature.

Benefits of NILOSURE 150 CAPSULE 4'SArrow

  • NILOSURE 150 CAPSULE 4'S is a targeted therapy specifically designed to combat Chronic Myelogenous Leukemia (CML). In CML, the BCR-ABL tyrosine kinase becomes abnormally active, leading to the excessive and uncontrolled proliferation of blood cells. NILOSURE 150 CAPSULE 4'S works by selectively inhibiting this BCR-ABL tyrosine kinase. By disrupting the kinase's signaling pathway, the medication effectively puts a halt to the out-of-control cell division characteristic of CML. This precise action helps to slow down or stop the progression of the disease, giving patients a better chance at managing their condition and improving their overall health.
  • Through its targeted mechanism, NILOSURE 150 CAPSULE 4'S aims to restore balance to blood cell production and reduce the number of cancerous cells in the body. This can lead to a decrease in symptoms associated with CML and improved quality of life for individuals undergoing treatment. Regular monitoring and adherence to the prescribed dosage are essential for optimal results.

How to use NILOSURE 150 CAPSULE 4'SArrow

  • Take NILOSURE 150 CAPSULE 4'S exactly as your doctor has prescribed. It is crucial to follow their instructions precisely for the best possible outcome. Generally, you should swallow the capsule whole with a glass of water. Avoid crushing, chewing, or breaking the capsule, as this could affect how the medication is absorbed by your body. The dosage and duration of treatment will be determined by your doctor based on factors such as your age, body weight, and the specific condition being treated. It's vital to adhere to the prescribed schedule and dosage.
  • Consistency is key when taking NILOSURE 150 CAPSULE 4'S. Try to take it at the same time each day to help you remember and to maintain a steady level of medication in your system. If you have any concerns about how to take the medication, or if you experience any difficulties swallowing the capsule, consult your doctor or pharmacist for guidance.
  • Do not discontinue NILOSURE 150 CAPSULE 4'S without first consulting your doctor. Even if you feel better, it's important to complete the full course of treatment as prescribed. Stopping the medication prematurely could lead to a relapse or worsening of your condition. If your doctor advises you to stop taking the medication, they will provide instructions on how to gradually reduce the dosage to minimize any potential side effects.

FAQs

Can NILOSURE 150 CAPSULE 4'S cause liver damage?Arrow

NILOSURE 150 CAPSULE 4'S may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking NILOSURE 150 CAPSULE 4'S. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

How does NILOSURE 150 CAPSULE 4'S differ from other medications used to treat chronic myeloid leukemia, such as Imatinib?Arrow

Imatinib, in its selectivity and potency. NILOSURE 150 CAPSULE 4'S is more selective for the BCR-ABL protein that drives the growth of cancer cells, and it is more potent in inhibiting the activity of this protein. NILOSURE 150 CAPSULE 4'S has also been shown to be effective in patients who have developed resistance to Imatinib.

What are the potential long-term effects of NILOSURE 150 CAPSULE 4'S on the body?Arrow

The potential long-term effects of NILOSURE 150 CAPSULE 4'S on the body include cardiovascular events, such as hypertension, arrhythmias, and heart failure, as well as liver dysfunction, pancreatic enzyme elevation, and fluid retention. These side effects are generally rare, but they can occur in some patients.

How to monitor the effects of NILOSURE 150 CAPSULE 4'S over the course of treatment?Arrow

It is monitored through regular blood tests, electrocardiograms, and imaging studies. Blood tests can assess liver and kidney function, blood counts, and electrolyte levels. ECG can detect any changes in heart rhythm or function. Imaging studies, such as echocardiograms and chest X-rays, can evaluate the heart and lungs for any signs of damage or fluid accumulation.

Who should not take NILOSURE 150 CAPSULE 4'S?Arrow

NILOSURE 150 CAPSULE 4'S should not be taken by pregnant or breastfeeding women, or by people with certain medical conditions such as severe liver or kidney disease, a history of pancreatitis, or a prolonged QT interval.

NULL interaction of NILOSURE 150 CAPSULE 4'S with other drugsArrow

There are no known interactions of NILOSURE 150 CAPSULE 4'S with other drugs.

Advice related to NILOSURE 150 CAPSULE 4'SArrow

Based on your condition your doctor may prescribe a lower dose. NILOSURE 150 CAPSULE 4'S can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.

What molecule/combination is used for making NILOSURE 150 CAPSULE 4'S?Arrow

NILOTINIB is the molecule used for making NILOSURE 150 CAPSULE 4'S.

For what ailments/diseases/conditions is NILOSURE 150 CAPSULE 4'S prescribed?Arrow

NILOSURE 150 CAPSULE 4'S is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo; Tyrosine Kinase Inhibitors

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Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium (EMC)

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Novartis, US Food & Drug Administration

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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