MIXTARD 30/70 100IU VIAL 10 ML

How MIXTARD 30/70 100IU VIAL 10 ML Works

• MIXTARD 30/70 100IU VIAL 10 ML is a premixed insulin formulation containing both rapid-acting and intermediate-acting human insulin. This combination helps to manage blood sugar levels effectively throughout the day. The '30/70' designation indicates the percentage of each type of insulin in the mix: 30% is rapid-acting insulin (also known as soluble insulin), and 70% is intermediate-acting insulin (also known as isophane insulin).
• The rapid-acting component of MIXTARD 30/70, the soluble insulin, starts working quickly after injection. Its primary function is to cover the insulin requirement during meals. When you eat, carbohydrates are broken down into glucose, which raises blood sugar levels. The rapid-acting insulin helps to quickly lower these post-meal glucose spikes, preventing hyperglycemia (high blood sugar). It achieves this by facilitating the uptake of glucose from the blood into cells, where it can be used for energy or stored for later use. This rapid action is essential for controlling blood sugar levels immediately after eating.
• The intermediate-acting component, the isophane insulin, has a slower onset and a longer duration of action compared to the rapid-acting insulin. It provides a background level of insulin that helps to control blood sugar levels between meals and during the night. The isophane insulin is formulated to release insulin gradually over a longer period, typically up to 24 hours, although the exact duration can vary from person to person. This sustained release helps to prevent hyperglycemia from occurring between meals and ensures a more stable blood sugar profile throughout the day.
• When injected subcutaneously (under the skin), MIXTARD 30/70 is absorbed into the bloodstream. Both the rapid-acting and intermediate-acting insulins then work in concert to regulate blood sugar levels. The rapid-acting insulin handles the immediate post-meal glucose surge, while the intermediate-acting insulin provides a baseline level of insulin to maintain blood sugar control between meals. The combination helps mimic the natural insulin release pattern of a healthy pancreas, providing better overall glycemic control.
• Insulin, in general, works by allowing glucose to enter the body's cells to provide energy. It binds to insulin receptors on cell surfaces, triggering a cascade of events that ultimately lead to the translocation of glucose transporters (GLUT4) to the cell membrane. These transporters then facilitate the uptake of glucose from the bloodstream into the cells of muscles, liver, and fat tissue. By promoting glucose uptake, insulin lowers blood sugar levels.
• MIXTARD 30/70 also inhibits the liver from producing more glucose. In individuals with diabetes, the liver may produce excessive amounts of glucose, contributing to hyperglycemia. Insulin helps to suppress this hepatic glucose production, further aiding in blood sugar control. Additionally, insulin promotes the storage of glucose as glycogen in the liver and muscles, providing a readily available energy reserve. It also encourages the storage of excess glucose as fat, preventing it from accumulating in the bloodstream.
• By combining rapid-acting and intermediate-acting insulins, MIXTARD 30/70 offers a convenient way to manage blood sugar levels for individuals with diabetes. The premixed formulation simplifies insulin therapy, reducing the need for multiple injections of different types of insulin. However, it is crucial to follow your doctor's instructions carefully regarding dosage, timing of injections, and monitoring of blood sugar levels to ensure optimal glycemic control and minimize the risk of hypoglycemia (low blood sugar).

Like all medicines, Mixtard 30/70 can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): This is the most common side effect. Symptoms can include cold sweat, cool pale skin, headache, rapid heartbeat, feeling sick, feeling very hungry, temporary vision changes, drowsiness, unusual tiredness and weakness, nervousness or tremor, feeling anxious, feeling confused, difficulty in concentrating. * Local reactions at the injection site: Redness, swelling, itching, or pain at the injection site. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Lipodystrophy: The fatty tissue under the skin at the injection site may shrink (lipoatrophy) or thicken (lipohypertrophy). Changing your injection site with each injection may help reduce the risk of developing these skin changes. * Allergic reactions: Symptoms may include hives, itching, rash, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing. * Edema: Swelling of the ankles, feet, or fingers. **Rare Side Effects (may affect up to 1 in 1,000 people):** * Diabetic Retinopathy: Eye disease **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Severe allergic reaction (anaphylactic reaction): Symptoms can include difficulty breathing, wheezing, rapid heartbeat, sweating, and feeling faint. * Peripheral neuropathy (nerve damage): This may cause pain, burning, tingling, numbness, or weakness in the extremities. **Other Possible Side Effects:** * Weight gain * Flu-like symptoms **Important Information:** * **Hypoglycemia:** It is very important to treat low blood sugar immediately to prevent it from becoming severe. Carry a source of sugar with you at all times (e.g., glucose tablets, candy).

• If you miss a dose of Mixtard 30/70, it is important to check your blood sugar levels as soon as you remember. Take your next dose at the usual time, but do not double the dose to make up for the missed one. Missing a dose can lead to hyperglycemia (high blood sugar). If you are unsure about what to do, consult your doctor or pharmacist for guidance.

• Keep MIXTARD 30/70 100IU VIAL 10ML away from the reach of children and pets.
• Store MIXTARD 30/70 100IU VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** Mixtard 30/70 is a premixed insulin, containing 30% rapid-acting and 70% intermediate-acting insulin. This means it provides both a quick burst of insulin to cover meals and a longer-lasting background insulin. Knowing this helps you coordinate your meals and activities.
• **Timing is Key:** Inject Mixtard 30/70 approximately 30 minutes before your meal. This allows the rapid-acting component to start working when your blood sugar begins to rise after eating. Consistency in timing is crucial for optimal blood sugar control.
• **Injection Technique Matters:** Always inject Mixtard 30/70 subcutaneously (under the skin) and rotate injection sites (e.g., abdomen, thigh, upper arm) to prevent lipodystrophy (skin thickening or pitting). Use a new needle for each injection to ensure sterility and reduce discomfort.
• **Monitor Your Blood Sugar Regularly:** Frequent blood sugar monitoring is essential when using Mixtard 30/70. This helps you understand how your body responds to the insulin and allows you to make necessary adjustments to your diet, exercise, or insulin dose in consultation with your doctor.
• **Be Prepared for Hypoglycemia:** Hypoglycemia (low blood sugar) is a potential side effect of insulin therapy. Carry a source of fast-acting carbohydrates (e.g., glucose tablets, juice) with you at all times and be aware of the symptoms of hypoglycemia (e.g., sweating, shakiness, confusion). Treat hypoglycemia promptly and inform your doctor if you experience frequent or severe episodes.
• **Storage is Important:** Store unopened Mixtard 30/70 vials in the refrigerator (2°C to 8°C). Once opened, the vial can be stored at room temperature (below 25°C) for up to 6 weeks. Protect from direct heat and light. Never use Mixtard 30/70 if it has been frozen or exposed to extreme temperatures.
• **Consult Your Doctor Regularly:** Regular check-ups with your doctor are vital to ensure your insulin therapy is effective and safe. Your doctor can adjust your insulin dose, monitor your overall health, and address any concerns you may have.

• MIXTARD 30/70 100IU VIAL 10 ML is typically administered subcutaneously, and its absorption is not significantly affected by food intake. Therefore, there are no specific dietary restrictions or recommendations related to the timing of meals in relation to MIXTARD 30/70 100IU VIAL 10 ML injections. Maintain a consistent diet and carbohydrate intake to help manage blood sugar levels effectively. Always follow your doctor's instructions regarding diet and insulin administration.