MIXTARD 30/70 FLEXPEN 3 ML

How MIXTARD 30/70 FLEXPEN 3 ML Works

• MIXTARD 30/70 FLEXPEN 3 ML is a premixed insulin formulation containing both rapid-acting and intermediate-acting human insulin. It's designed to help manage blood sugar levels in individuals with diabetes. Understanding how it works involves looking at the individual components and their combined effect.
• The rapid-acting component, also known as soluble insulin, starts working within 30 minutes of injection. It helps to cover the rise in blood sugar levels that occur after meals. This type of insulin mimics the natural insulin response the body would produce immediately following food intake.
• The intermediate-acting component, also known as isophane insulin, has a longer duration of action. It provides a background level of insulin, helping to control blood sugar levels between meals and during the night. This longer-acting insulin is made by combining insulin with protamine and zinc, which slows down its absorption from the injection site.
• When you inject MIXTARD 30/70 FLEXPEN 3 ML, the rapid-acting insulin starts to lower your blood sugar almost immediately, while the intermediate-acting insulin works gradually over a longer period. The '30/70' designation indicates that the mixture contains 30% rapid-acting insulin and 70% intermediate-acting insulin.
• Insulin works by allowing glucose (sugar) from the blood to enter cells, where it can be used for energy. In people with diabetes, the body either doesn't produce enough insulin or can't effectively use the insulin it produces. This leads to high blood sugar levels. By providing exogenous insulin, MIXTARD 30/70 FLEXPEN 3 ML helps to lower blood sugar levels and keep them within a target range.
• This medication is typically injected subcutaneously (under the skin). The FlexPen delivery system is designed for convenient and accurate dosing. It's important to follow your doctor's instructions regarding dosage, timing of injections, and monitoring of blood sugar levels. Regular monitoring helps ensure that the insulin is working effectively and that you're not experiencing hypoglycemia (low blood sugar).
• Factors like diet, exercise, stress, and other medications can affect how insulin works. It's essential to maintain a consistent lifestyle and work closely with your healthcare team to adjust your insulin regimen as needed. If you notice any changes in your blood sugar control, consult your doctor or diabetes educator.
• In summary, MIXTARD 30/70 FLEXPEN 3 ML is a combination insulin product that provides both rapid-acting and intermediate-acting insulin to help manage blood sugar levels throughout the day. Understanding the timing and duration of action of each component is crucial for effective diabetes management.

Like all medicines, Mixtard 30/70 FlexPen can cause side effects, although not everybody gets them. **Very Common (may affect more than 1 in 10 people):** * Low blood sugar (hypoglycaemia). **Common (may affect up to 1 in 10 people):** * Local reactions at the injection site: Redness, swelling, and itching at the injection site. * Swelling: Swelling may occur around your ankles and other joints. **Uncommon (may affect up to 1 in 100 people):** * Signs of allergy: Local reactions spread to other parts of the body. * Lipodystrophy: If you inject insulin too often at the same site, the fatty tissue under the skin at this site may shrink (lipoatrophy) or thicken (lipohypertrophy). Changing the injection site with each injection may help to prevent such skin changes. **Rare (may affect up to 1 in 1,000 people):** * Serious allergic reaction: If you have a serious allergic reaction to Mixtard 30/70 FlexPen, stop using Mixtard 30/70 FlexPen and see a doctor straight away. * Painful neuropathy (nerve pain) **Very rare (may affect up to 1 in 10,000 people):** * Vision problems **Other possible side effects:** * Skin changes at the injection site (Lipodystrophy) * Swollen joints * Diabetic retinopathy (an eye disease related to diabetes which can lead to vision loss).

• If you miss a dose of Mixtard 30/70 Flexpen, inject the dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not inject a double dose to make up for a missed one. Consult your doctor or healthcare provider for specific guidance based on your individual circumstances.

• Keep MIXTARD 30/70 FLEXPEN 3ML away from the reach of children and pets.
• Store MIXTARD 30/70 FLEXPEN 3ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Ratio:** Mixtard 30/70 FlexPen contains 30% soluble insulin and 70% isophane insulin. This fixed ratio might not be suitable for everyone. Regularly monitor your blood sugar levels and discuss with your doctor if adjustments to your insulin regimen are needed to achieve optimal control. Proper understanding of the insulin ratio can prevent both hyperglycemia and hypoglycemia. Factors like diet, exercise, and stress can significantly impact your insulin needs.
• **Prime the Pen Before Each Injection:** Always prime the FlexPen before each injection, even if it's a new pen. Dial 2 units and eject the insulin into the air until a drop appears. This ensures that the pen is working correctly and delivers the correct dose. Failure to prime the pen can lead to inaccurate dosing and potentially affect your blood sugar levels. Priming removes air bubbles that may have accumulated in the pen.
• **Rotate Injection Sites:** To prevent lipohypertrophy (thickening of the skin) or lipoatrophy (thinning of the skin), rotate your injection sites within the same general area (e.g., abdomen, thigh, or upper arm). Consistent injection in the same spot can affect insulin absorption and lead to unpredictable blood sugar levels. Develop a rotation schedule and stick to it. Consider using a visual aid or app to track injection sites.
• **Proper Storage is Crucial:** Store unopened Mixtard 30/70 FlexPens in the refrigerator (2°C to 8°C or 36°F to 46°F). Once in use, the pen can be stored at room temperature (below 30°C or 86°F) for up to 6 weeks, away from direct heat and sunlight. Never freeze insulin. Incorrect storage can degrade the insulin and reduce its effectiveness, leading to poor blood sugar control. Always check the expiration date before using.
• **Monitor Blood Sugar Regularly:** Regularly monitor your blood sugar levels as directed by your healthcare provider. This helps you understand how Mixtard 30/70 FlexPen is working for you and allows you to make necessary adjustments to your diet, exercise, or insulin dosage in consultation with your doctor. Keeping a log of your blood sugar readings can be invaluable in managing your diabetes effectively. Use a blood glucose meter and test strips that are accurate and reliable.

• MIXTARD 30/70 FLEXPEN 3 ML is usually administered before meals. It is important to maintain consistency in your meal timings and carbohydrate intake each day while using this medication.
• Consult your doctor if you need to change your diet, as dosage adjustments may be required. Be cautious about alcohol consumption as it can affect blood sugar levels.