NEBYKARE AM TABLET 10'S

How NEBYKARE AM TABLET 10'S Works

• NEBYKARE AM TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure) effectively. It combines two active ingredients, Nebivolol and Amlodipine, each working through different mechanisms to lower blood pressure and reduce the risk of cardiovascular events.
• Nebivolol is a beta-blocker with a unique mechanism of action. It selectively blocks beta-1 adrenergic receptors in the heart. By blocking these receptors, Nebivolol slows down the heart rate and reduces the force of heart muscle contraction. This leads to a decrease in cardiac output, which subsequently lowers blood pressure. Furthermore, Nebivolol stimulates the production of nitric oxide (NO) in the blood vessels. Nitric oxide is a vasodilator, meaning it helps relax and widen blood vessels, further contributing to the reduction of blood pressure. This dual action of reducing cardiac output and promoting vasodilation makes Nebivolol a potent anti-hypertensive agent.
• Amlodipine, on the other hand, is a calcium channel blocker. It works by blocking the entry of calcium ions into the smooth muscle cells of the blood vessel walls and heart muscle. Calcium ions are essential for muscle contraction. By reducing calcium influx, Amlodipine causes the smooth muscles in the blood vessels to relax. This relaxation leads to vasodilation, which lowers blood pressure. In addition, Amlodipine's effect on the heart muscle helps to reduce the force of contraction, further contributing to its blood pressure-lowering effects. Amlodipine is particularly effective in reducing systolic blood pressure.
• The synergistic action of Nebivolol and Amlodipine in NEBYKARE AM TABLET 10'S provides comprehensive blood pressure control. Nebivolol addresses the cardiac component of hypertension by reducing heart rate and cardiac output, while Amlodipine targets the vascular component by promoting vasodilation. Together, they provide a balanced approach to managing high blood pressure, reducing the strain on the heart and blood vessels, and minimizing the risk of complications such as heart attack, stroke, and kidney damage. This combination allows for effective blood pressure management with potentially fewer side effects compared to using higher doses of either medication alone. It is crucial to take NEBYKARE AM TABLET 10'S as prescribed by your doctor to achieve optimal results.

Possible side effects of Nebykare AM Tablet may include: * **Common:** Headache, dizziness, fatigue, sleepiness, nausea, flushing (feeling of warmth), palpitations (fast or irregular heartbeat), ankle swelling. * **Less Common:** Weakness, muscle cramps, diarrhea, constipation, visual disturbances, shortness of breath, skin rash or itching, hair loss, mood changes (including depression), erectile dysfunction. * **Rare:** Fainting, worsening of angina pectoris (chest pain), irregular heart rhythm, allergic reactions (swelling of the face, lips, or tongue; difficulty breathing), liver problems (yellowing of the skin or eyes), increased sweating, tingling or numbness in the extremities, tremor.

• If you miss a dose of NEBYKARE AM Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep NEBYKARE AM TAB 1X10 away from the reach of children and pets.
• Store NEBYKARE AM TAB 1X10 at room temperature.

• **Take NEBYKARE AM Tablet as Prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dosage yourself, even if you feel better or worse. Consistent adherence to the prescribed regimen is crucial for effective blood pressure and heart rate management.
• **Be Mindful of Potential Side Effects:** NEBYKARE AM Tablet can cause side effects such as dizziness, headache, fatigue, and swelling in the ankles or feet. If you experience any persistent or bothersome side effects, consult your doctor promptly. Do not ignore mild symptoms, as they may indicate a need for dosage adjustment or alternative medication.
• **Monitor Your Blood Pressure Regularly:** Keep a record of your blood pressure readings at home and share them with your doctor during check-ups. This will help assess the effectiveness of NEBYKARE AM Tablet and make necessary adjustments to your treatment plan. Consistent monitoring provides valuable insights into your cardiovascular health.
• **Maintain a Healthy Lifestyle:** Complement NEBYKARE AM Tablet with a heart-healthy lifestyle. This includes a balanced diet low in sodium and saturated fats, regular physical activity, maintaining a healthy weight, and avoiding smoking and excessive alcohol consumption. Lifestyle modifications can significantly enhance the benefits of the medication.
• **Avoid Grapefruit and Grapefruit Juice:** Grapefruit can interact with amlodipine, one of the active ingredients in NEBYKARE AM Tablet, potentially increasing its concentration in the blood and leading to increased side effects. Avoid consuming grapefruit or grapefruit juice while taking this medication to ensure its safe and effective use. Inform your doctor about all other medications and supplements you are taking to avoid any potential drug interactions.

• NEBYKARE AM Tablet 10'S is generally safe to take with food. However, it is best to take the medicine at a consistent time each day to maintain steady blood levels. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it may increase the drug's concentration in your body and potentially lead to increased side effects. Consult your doctor or pharmacist for personalized advice based on your specific health condition and other medications you may be taking.