pregabanyl nt tablet 10's
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PREGABANYL NT TABLET 10'S

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PREGABANYL NT TABLET 10'S

By LEEFORD HEALTHCARE LIMITED

MRP

145

₹60

58.62 % OFF

₹6 Only /

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Product DetailsArrow

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About PREGABANYL NT TABLET 10'S

  • Pregabanyl NT Tablet is a combination medicine for neuropathic (nerve) pain, containing pregabalin 75 mg and nortriptyline 10 mg. The two ingredients work together — or synergistically — to relieve the shooting, burning, and tingling discomfort of damaged nerves, and the combination is commonly prescribed when nerve pain also affects mood and sleep.
  • Pregabalin is an anticonvulsant and analgesic. It works by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of neurotransmitters such as glutamate, norepinephrine, and substance P, which are involved in pain transmission. By modulating these neurotransmitters, pregabalin helps decrease nerve excitability and reduce pain signals reaching the brain.
  • Nortriptyline, a tricyclic antidepressant, enhances the pain-relieving effect of pregabalin. It primarily works by inhibiting the reuptake of serotonin and norepinephrine in the brain. By increasing the availability of these neurotransmitters in the synaptic cleft, nortriptyline helps modulate pain pathways and improve mood. This dual action addresses both the physical and the emotional components of chronic pain, which often go together.
  • Pregabanyl NT Tablet is commonly prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Diabetic neuropathy is nerve damage caused by diabetes, leading to pain, numbness, and tingling, typically in the hands and feet. Postherpetic neuralgia is a complication of shingles marked by persistent pain after the shingles rash has healed. Fibromyalgia is a chronic condition of widespread musculoskeletal pain accompanied by fatigue, sleep disturbance, and mood changes.
  • The combination of pregabalin and nortriptyline in Pregabanyl NT Tablet offers a comprehensive approach to managing neuropathic pain by targeting both the underlying nerve activity and the associated mood disturbances. Patients should take this medication exactly as prescribed by their healthcare provider, keeping potential side effects such as drowsiness, dizziness, and dry mouth in mind, and discussing all other medicines they take to avoid interactions. It should be used under medical supervision, and doses should not be stopped abruptly without medical advice.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Pregabanyl NT Tablet 10's that is Pregabalin 75 Mg+nortriptyline 10 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of PREGABANYL NT TABLET 10'S

  • Neuropathic pain treatment
  • Fibromyalgia management
  • Postherpetic neuralgia relief
  • Diabetic neuropathy pain management
  • Spinal cord injury-related pain relief
  • Adjunctive treatment for partial seizures
  • Treatment of generalized anxiety disorder (GAD)

How PREGABANYL NT TABLET 10'S Works

  • PREGABANYL NT Tablet is a combination medication containing Pregabalin and Nortriptyline, both of which play distinct roles in managing neuropathic pain. Neuropathic pain arises from nerve damage or dysfunction, leading to abnormal pain signals being sent to the brain. This medication works synergistically to alleviate this type of pain.
  • Pregabalin, an anticonvulsant and analgesic, primarily functions by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium into nerve terminals. This modulation subsequently reduces the release of several excitatory neurotransmitters, including glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals. By decreasing their release, Pregabalin effectively dampens the overactive nerve signals that contribute to neuropathic pain, thus reducing pain intensity.
  • Nortriptyline, a tricyclic antidepressant (TCA), has a different mechanism of action. It primarily works by inhibiting the reuptake of neurotransmitters like serotonin and norepinephrine in the brain. By blocking the reuptake, Nortriptyline increases the concentration of these neurotransmitters in the synaptic cleft, the space between nerve cells. Elevated levels of serotonin and norepinephrine can help modulate pain pathways and improve mood. TCAs like Nortriptyline are thought to alleviate neuropathic pain by enhancing the descending inhibitory pathways, which are natural pain-modulating systems in the central nervous system. These pathways help to suppress pain signals.
  • The combination of Pregabalin and Nortriptyline in PREGABANYL NT Tablet provides a dual-pronged approach to managing neuropathic pain. Pregabalin directly reduces the release of excitatory neurotransmitters involved in pain transmission, while Nortriptyline enhances the activity of pain-modulating neurotransmitters and strengthens the body's natural pain control mechanisms. This synergistic action can lead to more effective pain relief compared to using either medication alone. It's important to note that the full effects of PREGABANYL NT Tablet may take several weeks to become apparent as the body adjusts to the medication and neurotransmitter levels stabilize.
  • Furthermore, it's crucial to take PREGABANYL NT Tablet as prescribed by your doctor. Adhering to the recommended dosage and schedule is essential for optimal pain management and to minimize potential side effects. If you have any questions or concerns about how PREGABANYL NT Tablet works or are experiencing any adverse effects, consult your healthcare provider.

Side Effects of PREGABANYL NT TABLET 10'SArrow

Common side effects of Pregabanyl NT Tablet may include: Dizziness, sleepiness, uncoordinated body movements, fatigue, blurred vision, dry mouth, difficulty in concentration, edema (swelling), weight gain, tremors, convulsions, increased appetite, euphoria, confusion, decreased libido, irritability, disorientation, insomnia. Less common or rare side effects may include: Visual disturbances, changes in heart rhythm, memory impairment, cognitive dysfunction, speech disorder, muscle twitching, decreased blood pressure, allergic reactions (rashes, itching, swelling), Stevens-Johnson syndrome, angioedema (swelling under the skin), rhabdomyolysis (muscle breakdown), pancreatitis, hepatitis, kidney failure, gynecomastia (enlargement of male breasts), breast pain, galactorrhea (abnormal milk secretion), menstrual disturbances, thrombocytopenia (low platelet count), suicidal thoughts or behavior.

  • Pregabanyl NT Tablet, side effects, dizziness, sleepiness, edema, weight gain, blurred vision, dry mouth, allergic reaction, Hindi, Gujarati

Safety Advice for PREGABANYL NT TABLET 10'SArrow

alcohol

Alcohol

Alcohol

It is unsafe to consume alcohol while taking Pregabanyl NT Tablet 10's.

pregnancy

Pregnancy

Pregnancy

Pregabanyl NT Tablet 10's is unsafe to use during pregnancy.

breast_feeding

BreastFeeding

BreastFeeding

Pregabanyl NT Tablet 10's is unsafe to use during breastfeeding.

driving

Driving

Driving

Use caution when driving while taking Pregabanyl NT Tablet 10's.

kidney

Kidney Function

Kidney Function

Pregabanyl NT Tablet 10's should be used with caution in patients with kidney disease.

liver

Liver Function

Liver Function

Pregabanyl NT Tablet 10's should be used with caution in patients with liver disease.

allergies

Allergies

Allergies

Do not use Pregabanyl NT Tablet 10's if you are allergic to it or any of its ingredients.

Dosage of PREGABANYL NT TABLET 10'SArrow

  • The dosage of PREGABANYL NT TABLET 10'S should be strictly as prescribed by your physician. It is typically initiated at a lower dose and gradually increased based on individual patient response and tolerability. The usual starting dose is 75 mg twice daily or 50 mg three times daily. This can be increased to a maximum dose of 300 mg per day within one week, depending on the doctor’s assessment.
  • For patients with neuropathic pain, the dosage may vary depending on the type and severity of pain. The maintenance dose typically ranges from 150 mg to 600 mg per day, divided into two or three doses. It is crucial to adhere to the prescribed dosage schedule to maintain consistent blood levels of the medication and achieve optimal pain relief.
  • In the treatment of anxiety disorders, the initial dose is usually lower, and the titration is slower to minimize potential side effects. Similarly, for fibromyalgia, the dosage is adjusted based on individual pain levels and functional capacity. Patients with kidney problems (renal impairment) may require dosage adjustments to prevent drug accumulation and associated side effects; hence, consult your doctor before changing anything.
  • It's important to take PREGABANYL NT TABLET 10'S at the same time each day to maintain a consistent level of medication in your system. Do not stop taking this medicine suddenly without consulting your doctor, as this may lead to withdrawal symptoms. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Take 'PREGABANYL NT TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of PREGABANYL NT TABLET 10'S?Arrow

  • If you miss a dose of Pregabanyl NT, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store PREGABANYL NT TABLET 10'S?Arrow

  • Keep PREGABANYL NT TAB 1X10 away from the reach of children and pets.
  • Store PREGABANYL NT TAB 1X10 at room temperature.

Benefits of PREGABANYL NT TABLET 10'SArrow

  • PREGABANYL NT TABLET 10'S offers a multifaceted approach to managing neuropathic pain, a condition arising from nerve damage that can cause debilitating discomfort. By combining pregabalin and nortriptyline, this medication provides synergistic relief, targeting pain signals at multiple levels. Pregabalin, an anticonvulsant, modulates the release of neurotransmitters involved in pain transmission, effectively calming overactive nerves and reducing the intensity of pain sensations. This action is particularly beneficial for conditions like diabetic neuropathy, postherpetic neuralgia, and fibromyalgia, where nerve pain is a primary symptom.
  • Nortriptyline, a tricyclic antidepressant, complements pregabalin's effects by enhancing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain. These neurotransmitters play a crucial role in mood regulation and pain modulation. By increasing their availability, nortriptyline not only helps alleviate pain but also addresses the emotional distress that often accompanies chronic pain conditions. This dual action makes PREGABANYL NT TABLET 10'S particularly effective in managing pain associated with mood disorders like depression and anxiety.
  • Beyond pain relief, PREGABANYL NT TABLET 10'S can improve the overall quality of life for individuals suffering from neuropathic pain. By reducing pain intensity and improving mood, this medication can enhance sleep quality, allowing for more restful nights and increased energy levels during the day. This, in turn, can lead to improved physical function, allowing individuals to engage in daily activities with greater ease and comfort. Furthermore, the reduction in pain and emotional distress can foster a greater sense of well-being and improve social interactions.
  • The combined action of pregabalin and nortriptyline in PREGABANYL NT TABLET 10'S can also lead to a reduction in the reliance on other pain medications, such as opioids, which carry a risk of addiction and other adverse effects. By effectively managing pain with a targeted approach, this medication can help individuals avoid the potential complications associated with long-term opioid use. This is particularly important in the context of the ongoing opioid crisis, where safer and more effective pain management strategies are urgently needed.
  • Moreover, PREGABANYL NT TABLET 10'S can be tailored to individual needs, with dosage adjustments made based on the severity of pain and individual response to the medication. This allows for a personalized approach to pain management, ensuring that individuals receive the optimal dose for their specific condition. Regular monitoring by a healthcare professional is essential to ensure the safety and effectiveness of treatment. With careful management, PREGABANYL NT TABLET 10'S can provide significant and sustained relief from neuropathic pain, improving the overall well-being and quality of life for those affected.

How to use PREGABANYL NT TABLET 10'SArrow

  • PREGABANYL NT TABLET 10'S should be taken orally, exactly as prescribed by your doctor. It is typically taken once or twice daily, depending on your condition and how you respond to the medication. To ensure consistent absorption, try to take it at the same time(s) each day.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released in your body. You can take PREGABANYL NT TABLET 10'S with or without food. However, if you experience stomach upset, taking it with food might help.
  • The dosage will be determined by your doctor based on your medical condition, kidney function, and other medications you may be taking. It's crucial to follow your doctor's instructions precisely and not adjust the dosage on your own. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Continue taking PREGABANYL NT TABLET 10'S for the full duration prescribed by your doctor, even if you feel better. Do not stop taking the medication suddenly without consulting your doctor, as this can lead to withdrawal symptoms. If you need to stop taking the medication, your doctor will gradually reduce the dosage over time to minimize the risk of withdrawal symptoms. It is advisable to have regular check-ups with your doctor while taking this medication to monitor your progress and check for any side effects.

Quick Tips for PREGABANYL NT TABLET 10'SArrow

  • Take PREGABANYL NT TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting them, even if you feel better. This medication is typically used to manage nerve pain and certain types of seizures, and consistent use is important for its effectiveness.
  • Be aware of potential side effects. Common side effects of PREGABANYL NT TABLET 10'S include dizziness, drowsiness, blurred vision, and weight gain. If these side effects are persistent or bothersome, inform your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. PREGABANYL NT TABLET 10'S can interact with other substances, potentially affecting how it works or increasing the risk of side effects. It's crucial to provide a complete medication history to your healthcare provider.
  • If you miss a dose of PREGABANYL NT TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Maintain a consistent schedule to ensure steady levels of the medication in your body.
  • Store PREGABANYL NT TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. If you have any unused medication, dispose of it properly according to your local regulations. Consult your pharmacist for guidance on safe disposal methods.

Food Interactions with PREGABANYL NT TABLET 10'SArrow

  • PREGABANYL NT TABLET 10'S can be taken with or without food. The absorption of pregabalin, one of the active ingredients, is not significantly affected by food intake. However, taking the medication at the same time each day can help maintain consistent blood levels and improve its effectiveness.

FAQs

What is PREGABANYL NT TABLET 10'S?Arrow

PREGABANYL NT TABLET 10'S is a combination medicine used to treat neuropathic pain. It contains Pregabalin and Nortriptyline.

What is PREGABANYL NT TABLET 10'S used for?Arrow

This medicine is primarily used to treat neuropathic pain, which is caused by nerve damage.

What are the common side effects of PREGABANYL NT TABLET 10'S?Arrow

Common side effects include dizziness, sleepiness, dry mouth, constipation, and weight gain.

How does PREGABANYL NT TABLET 10'S work?Arrow

This medicine works by reducing pain signals in the brain. Pregabalin reduces pain signals, while Nortriptyline modulates nerve activity.

Is PREGABANYL NT TABLET 10'S addictive?Arrow

There may be a risk of some dependence with Pregabalin, so it should only be taken for the dose and duration prescribed by a doctor.

Can I drink alcohol with PREGABANYL NT TABLET 10'S?Arrow

Drinking alcohol can increase the side effects of this medicine, such as dizziness and drowsiness. Therefore, alcohol should be avoided.

How to store PREGABANYL NT TABLET 10'S?Arrow

Store it at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.

Is PREGABANYL NT TABLET 10'S safe for pregnant women?Arrow

Consult a doctor before using this medicine during pregnancy, as it may harm the fetus.

What should I do if I miss a dose of PREGABANYL NT TABLET 10'S?Arrow

If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Can PREGABANYL NT TABLET 10'S cause weight gain?Arrow

Yes, some patients may experience weight gain with this medicine.

Can PREGABANYL NT TABLET 10'S be taken on an empty stomach?Arrow

This medicine can be taken with or without food, but it is better to take it regularly.

Can PREGABANYL NT TABLET 10'S interact with other medications?Arrow

Yes, this medicine can interact with certain other medications. Tell your doctor about all your medications.

What should I avoid while taking PREGABANYL NT TABLET 10'S?Arrow

Avoid driving or operating heavy machinery as it can cause dizziness or drowsiness.

Should PREGABANYL NT TABLET 10'S be stopped abruptly?Arrow

No, this medicine should not be stopped abruptly. Consult your doctor to gradually reduce the dosage.

What are the symptoms of an overdose of PREGABANYL NT TABLET 10'S?Arrow

Symptoms of an overdose may include drowsiness, confusion, restlessness, and seizures. Seek immediate medical attention.

What is the composition of Pregabanyl Nt Tablet 10's?Arrow

Pregabanyl Nt Tablet 10's contains Nortriptyline 10 MG + Pregabalin 75 MG. It is a tricyclic antidepressant; and gabapentinoid; alpha-2-delta calcium channel ligand.

What are the side effects of Pregabanyl Nt Tablet 10's?Arrow

Commonly reported side effects of Pregabanyl Nt Tablet 10's include dry mouth, constipation, blurred vision, drowsiness, urinary retention, dizziness on standing, weight gain; and dizziness, drowsiness, weight gain, dry mouth, blurred vision, swelling of hands and feet, difficulty concentrating. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Pregabanyl Nt Tablet 10's?Arrow

Pregabanyl Nt Tablet 10's is listed at Rs. 60 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Pregabanyl Nt Tablet 10's?Arrow

Antidepressants carry a warning for increased suicidal thinking in children, adolescents and young adults — monitoring is needed; and Impairs driving and machine operation. Tell your doctor about all other medicines you take before starting Pregabanyl Nt Tablet 10's.

What is the correct dosage of Pregabanyl Nt Tablet 10's?Arrow

The dose of Pregabanyl Nt Tablet 10's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Pregabanyl Nt Tablet 10's?Arrow

A generic medicine is one with the same active composition as the branded product — for Pregabanyl Nt Tablet 10's that is Nortriptyline 10 MG + Pregabalin 75 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Pregabanyl Nt Tablet 10's.

Is Pregabanyl Nt Tablet 10's a prescription medicine?Arrow

Yes. Pregabanyl Nt Tablet 10's requires a valid doctor's prescription.

Who is the manufacturer of Pregabanyl Nt Tablet 10's?Arrow

Pregabanyl Nt Tablet 10's is manufactured by Leeford Healthcare Limited.

What is the dosage form of Pregabanyl Nt Tablet 10's?Arrow

Pregabanyl Nt Tablet 10's is supplied as a tablet and is taken by the oral route.

What are the benefits of Pregabanyl Nt Tablet 10's?Arrow

Pregabanyl Nt Tablet 10's contains Nortriptyline 10 MG + Pregabalin 75 MG. It is used for depression; also used at lower doses for neuropathic pain and migraine prevention under medical direction; and neuropathic pain; adjunct treatment of partial-onset seizures; generalised anxiety disorder and fibromyalgia in some settings. The benefit you get depends on the condition your doctor prescribed Pregabanyl Nt Tablet 10's for.

Is Pregabanyl Nt Tablet 10's safe to take daily?Arrow

Whether Pregabanyl Nt Tablet 10's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Pregabanyl Nt Tablet 10's on your own.

When should Pregabanyl Nt Tablet 10's be taken — morning or night?Arrow

The timing of Pregabanyl Nt Tablet 10's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Pregabanyl Nt Tablet 10's without a doctor's consultation?Arrow

No. Pregabanyl Nt Tablet 10's is a prescription medicine and should only be taken on a doctor's advice.

Can Pregabanyl Nt Tablet 10's be taken during pregnancy or breastfeeding?Arrow

Do not take Pregabanyl Nt Tablet 10's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Pregabanyl Nt Tablet 10's?Arrow

Check with your doctor before drinking alcohol while taking Pregabanyl Nt Tablet 10's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Pregabanyl Nt Tablet 10's be stored?Arrow

Store Pregabanyl Nt Tablet 10's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

Why is Pregabanyl Nt Tablet 10's not available?Arrow

Pregabanyl Nt Tablet 10's is marked discontinued on Medkart and cannot be ordered. Speak to your doctor or pharmacist about alternatives with the same composition.

References

Book Icon

Pregabalin DrugBank entry - comprehensive information on pregabalin's mechanism of action, pharmacokinetics, and interactions.

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Book Icon

Pregabalin PubChem entry - provides chemical properties, structure, and safety information for pregabalin.

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Book Icon

FDA label for pregabalin - official prescribing information, including indications, dosage, and adverse effects.

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Book Icon

Efficacy and Safety of Pregabalin in the Treatment of Neuropathic Pain: A Comprehensive Review - research article reviewing the effectiveness and safety of pregabalin for neuropathic pain.

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Lyrica (pregabalin) EMA assessment report - European Medicines Agency assessment report for pregabalin, including details on clinical trials and efficacy.

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Book Icon

RxList entry for pregabalin - patient-oriented information, but includes some technical details and warnings.

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Book Icon

Summary of Product Characteristics (SmPC) for pregabalin - detailed information intended for healthcare professionals, covering uses, dosage, contraindications, and side effects.

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Book Icon

Nortriptyline - A Review of its Pharmacology, Clinical Use, and Tolerability - research article reviewing the effectiveness and safety of Nortriptyline for neuropathic pain.

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Book Icon

Nortriptyline DrugBank entry - comprehensive information on Nortriptyline's mechanism of action, pharmacokinetics, and interactions.

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Book Icon

Nortriptyline PubChem entry - provides chemical properties, structure, and safety information for Nortriptyline.

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Ratings & Review

Good series, satisfied customer

Sameer Jadhav

Reviewed on 06-01-2024

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)

Nice discount and best quality medicine generic ..thank you

Mihir Ujjaniya

Reviewed on 29-12-2023

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(4/5)

Quick service, getting discounts on medicines on regular basis

Harshit Patel

Reviewed on 12-02-2024

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(5/5)

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

Reviewed on 05-12-2022

Start FilledStart FilledStart FilledStart EmptyStart Empty

(3/5)

वेरी गुड एक्सीलेंट

bhavtosh vyas

Reviewed on 31-01-2024

Start FilledStart FilledStart FilledStart FilledStart Filled

(5/5)


Marketer / Manufacturer Details

LEEFORD HEALTHCARE LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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