PREGABANYL NT TABLET 10'S

How PREGABANYL NT TABLET 10'S Works

• PREGABANYL NT Tablet is a combination medication containing Pregabalin and Nortriptyline, both of which play distinct roles in managing neuropathic pain. Neuropathic pain arises from nerve damage or dysfunction, leading to abnormal pain signals being sent to the brain. This medication works synergistically to alleviate this type of pain.
• Pregabalin, an anticonvulsant and analgesic, primarily functions by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium into nerve terminals. This modulation subsequently reduces the release of several excitatory neurotransmitters, including glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals. By decreasing their release, Pregabalin effectively dampens the overactive nerve signals that contribute to neuropathic pain, thus reducing pain intensity.
• Nortriptyline, a tricyclic antidepressant (TCA), has a different mechanism of action. It primarily works by inhibiting the reuptake of neurotransmitters like serotonin and norepinephrine in the brain. By blocking the reuptake, Nortriptyline increases the concentration of these neurotransmitters in the synaptic cleft, the space between nerve cells. Elevated levels of serotonin and norepinephrine can help modulate pain pathways and improve mood. TCAs like Nortriptyline are thought to alleviate neuropathic pain by enhancing the descending inhibitory pathways, which are natural pain-modulating systems in the central nervous system. These pathways help to suppress pain signals.
• The combination of Pregabalin and Nortriptyline in PREGABANYL NT Tablet provides a dual-pronged approach to managing neuropathic pain. Pregabalin directly reduces the release of excitatory neurotransmitters involved in pain transmission, while Nortriptyline enhances the activity of pain-modulating neurotransmitters and strengthens the body's natural pain control mechanisms. This synergistic action can lead to more effective pain relief compared to using either medication alone. It's important to note that the full effects of PREGABANYL NT Tablet may take several weeks to become apparent as the body adjusts to the medication and neurotransmitter levels stabilize.
• Furthermore, it's crucial to take PREGABANYL NT Tablet as prescribed by your doctor. Adhering to the recommended dosage and schedule is essential for optimal pain management and to minimize potential side effects. If you have any questions or concerns about how PREGABANYL NT Tablet works or are experiencing any adverse effects, consult your healthcare provider.

Common side effects of Pregabanyl NT Tablet may include: Dizziness, sleepiness, uncoordinated body movements, fatigue, blurred vision, dry mouth, difficulty in concentration, edema (swelling), weight gain, tremors, convulsions, increased appetite, euphoria, confusion, decreased libido, irritability, disorientation, insomnia. Less common or rare side effects may include: Visual disturbances, changes in heart rhythm, memory impairment, cognitive dysfunction, speech disorder, muscle twitching, decreased blood pressure, allergic reactions (rashes, itching, swelling), Stevens-Johnson syndrome, angioedema (swelling under the skin), rhabdomyolysis (muscle breakdown), pancreatitis, hepatitis, kidney failure, gynecomastia (enlargement of male breasts), breast pain, galactorrhea (abnormal milk secretion), menstrual disturbances, thrombocytopenia (low platelet count), suicidal thoughts or behavior.

• If you miss a dose of Pregabanyl NT, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGABANYL NT TAB 1X10 away from the reach of children and pets.
• Store PREGABANYL NT TAB 1X10 at room temperature.

• Take PREGABANYL NT TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting them, even if you feel better. This medication is typically used to manage nerve pain and certain types of seizures, and consistent use is important for its effectiveness.
• Be aware of potential side effects. Common side effects of PREGABANYL NT TABLET 10'S include dizziness, drowsiness, blurred vision, and weight gain. If these side effects are persistent or bothersome, inform your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. PREGABANYL NT TABLET 10'S can interact with other substances, potentially affecting how it works or increasing the risk of side effects. It's crucial to provide a complete medication history to your healthcare provider.
• If you miss a dose of PREGABANYL NT TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Maintain a consistent schedule to ensure steady levels of the medication in your body.
• Store PREGABANYL NT TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. If you have any unused medication, dispose of it properly according to your local regulations. Consult your pharmacist for guidance on safe disposal methods.

• PREGABANYL NT TABLET 10'S can be taken with or without food. The absorption of pregabalin, one of the active ingredients, is not significantly affected by food intake. However, taking the medication at the same time each day can help maintain consistent blood levels and improve its effectiveness.