PREGAMER NT TABLET 10'S

How PREGAMER NT TABLET 10'S Works

• PREGAMER NT Tablet 10'S is a combination medicine used to treat neuropathic pain. This medication works through a multifaceted approach by targeting different mechanisms involved in pain transmission and perception. It contains Pregabalin, Nortriptyline and Methylcobalamin as active ingredients.
• Pregabalin, an anticonvulsant, primarily binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin reduces the influx of calcium into nerve terminals. This action subsequently inhibits the release of several excitatory neurotransmitters, such as glutamate, noradrenaline, and substance P. By decreasing the release of these neurotransmitters, Pregabalin effectively dampens the overactivity of nerves that contribute to neuropathic pain. This helps in reducing the sensation of pain signals being sent to the brain.
• Nortriptyline, a tricyclic antidepressant, works by increasing the levels of certain neurotransmitters in the brain, specifically serotonin and norepinephrine. It achieves this by inhibiting their reuptake in the synaptic cleft, which is the space between nerve cells. When serotonin and norepinephrine levels are elevated, they can modulate pain signals. These neurotransmitters play a role in the descending pain pathways, which are natural mechanisms in the body that help to suppress pain. By enhancing these pathways, Nortriptyline helps to reduce the perception of chronic pain.
• Methylcobalamin is a form of vitamin B12 and plays a vital role in nerve health. It helps in the regeneration of damaged nerves and supports the formation of myelin, a protective sheath around nerve fibers. In neuropathic pain, nerve damage is often a significant factor. By promoting nerve regeneration and maintaining myelin integrity, Methylcobalamin can improve nerve function and reduce pain symptoms. It also possesses neuroprotective properties that can further contribute to the relief of neuropathic pain.
• The combined action of Pregabalin, Nortriptyline, and Methylcobalamin addresses multiple facets of neuropathic pain. Pregabalin reduces nerve excitability, Nortriptyline modulates pain signals through neurotransmitter regulation, and Methylcobalamin supports nerve health and regeneration. This synergistic effect provides comprehensive pain relief for individuals suffering from neuropathic pain by targeting the source and transmission of pain signals.

Common side effects of Pregamer NT Tablet may include: * Dizziness * Sleepiness * Uncoordinated body movements * Fatigue * Blurred vision * Dryness in mouth * Difficulty in paying attention * Weight gain * Peripheral edema (swelling of the extremities) Less common side effects may include: * Headache * Nausea * Vomiting * Constipation * Diarrhea * Memory impairment * Confusion * Tremor * Speech disorder * Increased appetite * Muscle cramp * Visual impairment * Decreased libido * Erectile dysfunction * Mood changes * Anxiety * Skin rash * Itching * Changes in blood pressure * Changes in heart rate Rare side effects may include: * Serious allergic reactions (e.g., angioedema, anaphylaxis) * Suicidal thoughts * Liver problems * Muscle damage * Severe skin reactions (e.g., Stevens-Johnson syndrome) This is not an exhaustive list. If you experience any unusual symptoms while taking Pregamer NT Tablet, inform your doctor immediately.

• If you miss a dose of PREGAMER NT TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGAMER NT TAB 1X10 away from the reach of children and pets.
• Store PREGAMER NT TAB 1X10 at room temperature.

• Take PREGAMER NT TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting them, as this can lead to withdrawal symptoms or a worsening of your condition. It's crucial to adhere to your doctor's instructions for optimal results and to minimize potential side effects.
• PREGAMER NT TABLET 10'S can cause drowsiness or dizziness, especially when you first start taking it. Avoid activities that require alertness, such as driving or operating machinery, until you know how the medicine affects you. It's best to take your first dose at bedtime to assess its impact on your alertness. If these side effects persist, consult your doctor.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting PREGAMER NT TABLET 10'S. This medicine can interact with other substances, potentially leading to unwanted side effects or reduced effectiveness. Pay close attention to any new or worsening symptoms after starting PREGAMER NT TABLET 10'S and report them to your doctor promptly.
• Be patient and consistent with your treatment. It may take several weeks for you to experience the full benefits of PREGAMER NT TABLET 10'S. Do not get discouraged if you don't feel better immediately. Continue taking the medicine as prescribed and attend regular follow-up appointments with your doctor to monitor your progress and address any concerns. Consistent adherence is key to achieving the desired therapeutic outcome.
• Store PREGAMER NT TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the medicine's effectiveness and prevents accidental ingestion. Do not use the medicine if it has expired or if the packaging is damaged. Dispose of expired or unused medicine properly according to local regulations.

• PREGAMER NT TABLET 10'S may be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent medicine levels in the body. Discuss with your doctor any specific dietary concerns you may have while on this medication.