RABIPUR INJECTION 5 ML

How RABIPUR INJECTION 5 ML Works

• RABIPUR INJECTION 5 ML is a rabies vaccine designed to provide active immunization against rabies. It works by stimulating the body's immune system to produce antibodies that neutralize the rabies virus. The vaccine contains inactivated rabies virus particles, which are incapable of causing the disease but are sufficient to trigger an immune response.
• Upon injection, the immune system recognizes the inactivated rabies virus as a foreign substance and initiates a cascade of immune responses. Antigen-presenting cells, such as dendritic cells, engulf the viral particles and present viral antigens to T helper cells. This activates the T helper cells, which then help activate B cells.
• The activated B cells differentiate into plasma cells, which are specialized cells that produce antibodies specific to the rabies virus. These antibodies bind to the rabies virus, preventing it from infecting cells and neutralizing its ability to cause disease. The antibodies also mark the virus for destruction by other immune cells.
• In addition to antibody production, RABIPUR INJECTION also stimulates the production of memory B cells and memory T cells. These memory cells remain in the body for a long time after vaccination and provide long-term immunity against rabies. If the vaccinated individual is later exposed to the rabies virus, these memory cells can quickly recognize the virus and mount a rapid and effective immune response, preventing the development of rabies.
• The effectiveness of RABIPUR INJECTION relies on the body's ability to generate a sufficient antibody response. The vaccination schedule, which typically involves multiple doses, is designed to maximize antibody production and ensure long-lasting immunity. Post-exposure prophylaxis (PEP) with RABIPUR INJECTION, often administered with rabies immunoglobulin (RIG), is crucial for individuals who have been exposed to the virus but have not been previously vaccinated. The RIG provides immediate passive immunity by directly neutralizing the virus, while the vaccine stimulates active immunity for long-term protection. Proper administration and adherence to the recommended vaccination schedule are essential for achieving optimal protection against rabies.

Common side effects of Rabipur injection include injection site reactions (pain, redness, swelling), headache, muscle pain (myalgia), fever, fatigue, and nausea. Less common side effects may include dizziness, joint pain (arthralgia), gastrointestinal disturbances (vomiting, abdominal pain, diarrhea), and allergic reactions (rash, itching, hives). In rare cases, more serious side effects such as neurological complications (Guillain-Barré syndrome, encephalitis) have been reported. Seek immediate medical attention if you experience any signs of a severe allergic reaction or neurological symptoms.

• If you miss a dose of Rabipur, contact your doctor as soon as possible to reschedule the injection. It is crucial to complete the full course of rabies vaccination to ensure maximum protection.

• Keep RABIPUR INJ 5ML away from the reach of children and pets.
• Store RABIPUR INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

• **Complete the Vaccination Schedule:** It's crucial to complete the entire course of Rabipur injections as prescribed by your doctor, even if you feel better or the animal appears healthy later. Incomplete vaccination may leave you vulnerable to rabies.
• **Seek Immediate Medical Attention After Exposure:** If you've been bitten, scratched, or licked on broken skin by a potentially rabid animal (dog, cat, bat, etc.), wash the wound thoroughly with soap and water for at least 15 minutes and seek immediate medical attention. Rabipur is most effective when administered promptly after exposure.
• **Inform Your Doctor About Existing Conditions and Medications:** Before receiving Rabipur, inform your doctor about any pre-existing medical conditions, allergies, or medications you are currently taking, including over-the-counter drugs and herbal supplements. This helps prevent potential drug interactions or adverse reactions.
• **Report Any Side Effects:** While Rabipur is generally safe, some common side effects may occur, such as pain, redness, or swelling at the injection site, fever, headache, or muscle aches. Report any persistent or severe side effects to your doctor promptly.
• **Avoid Alcohol and Strenuous Activity:** After receiving the Rabipur injection, it's advisable to avoid alcohol and strenuous physical activity for a few days. These can potentially weaken your immune system and affect the vaccine's efficacy. Consult your doctor for specific recommendations based on your individual health condition.
• **Rabies is Fatal if Untreated:** Remember that rabies is a deadly disease if left untreated. Do not delay seeking medical care after potential exposure. Rabipur, when administered correctly and promptly, is highly effective in preventing rabies.
• **Understand Post-Exposure Prophylaxis (PEP):** Rabipur is often used as part of PEP, which may also include rabies immunoglobulin (RIG). Your doctor will determine if you need RIG based on the severity and location of the wound, as well as the animal's vaccination status. Understand the complete PEP protocol recommended for your situation.
• **Safe Handling and Disposal of Sharps:** If you are administering Rabipur at home (in certain circumstances), ensure you are trained in proper injection techniques and safe disposal of needles and syringes. Use a puncture-resistant sharps container and follow local guidelines for disposal to prevent accidental needle sticks and potential infections.

• RABIPUR INJECTION 5 ML does not have any known interactions with food. It can be administered without regard to food intake.