TACROGRAF 0.25MG CAPSULE 10'S
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TACROGRAF 0.25MG CAPSULE 10'S

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TACROGRAF 0.25MG CAPSULE 10'S

By BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

MRP

184

₹135

26.63 % OFF

₹13.5 Only /

CAPSULE

58

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Product DetailsArrow

About TACROGRAF 0.25MG CAPSULE 10'S

  • TACROGRAF 0.25MG CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ.
  • Do not take this TACROGRAF 0.25MG CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
  • It is crucial to adhere to your doctor's instructions regarding dosage and monitoring while taking TACROGRAF 0.25MG CAPSULE 10'S. Regular blood tests are necessary to monitor the level of tacrolimus in your system and to ensure that it remains within the therapeutic range. Dosage adjustments may be required based on these blood tests, and it's important not to miss any scheduled appointments. Your doctor will also monitor for potential side effects and interactions with other medications you may be taking.
  • Limit exposure to sunlight and UV light while consuming TACROGRAF 0.25MG CAPSULE 10'S by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them.
  • Before starting TACROGRAF 0.25MG CAPSULE 10'S, discuss your complete medical history with your doctor, including any existing conditions or medications you are taking. This information will help your doctor assess the suitability of the medication for you and minimize any potential risks. It is especially important to discuss any infections, kidney problems, or neurological disorders you may have.
  • It is important to take TACROGRAF 0.25MG CAPSULE 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider. Stopping the medication abruptly can increase the risk of organ rejection. If you experience any bothersome or persistent side effects, inform your doctor promptly.

Uses of TACROGRAF 0.25MG CAPSULE 10'S

  • Prevent organ transplant rejections. Helps to lower the chances of the body rejecting the transplanted organ.

How TACROGRAF 0.25MG CAPSULE 10'S Works

  • TACROGRAF 0.25MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
  • TACROGRAF 0.25MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, TACROGRAF 0.25MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, TACROGRAF 0.25MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of TACROGRAF 0.25MG CAPSULE 10'S in skin disorders is not fully understood.

Side Effects of TACROGRAF 0.25MG CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for TACROGRAF 0.25MG CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, TACROGRAF 0.25MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of TACROGRAF 0.25MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 0.25MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take TACROGRAF 0.25MG CAPSULE 10'S exactly as prescribed by your doctor. Carefully follow their instructions regarding the timing and amount of medication to take.
  • To ensure optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. Swallow each capsule whole with a full glass of water. This helps the medication to be properly released and absorbed into your system.
  • For best results, take TACROGRAF 0.25MG CAPSULE 10'S on an empty stomach. This means taking it either at least 1 hour before a meal or waiting 2 to 3 hours after eating. This helps to avoid potential interactions with food that could affect how well the medication is absorbed.
  • Consistency is key to the success of your treatment. Try to take TACROGRAF 0.25MG CAPSULE 10'S at the same time(s) each day to maintain a steady level of the medication in your bloodstream. If you have any questions or concerns about the correct dosage or how to take TACROGRAF 0.25MG CAPSULE 10'S, don't hesitate to ask your doctor or pharmacist for clarification.

How to store TACROGRAF 0.25MG CAPSULE 10'S?Arrow

  • Keep TACROGRAF 0.25MG CAP 1X10 away from the reach of children and pets.
  • Store TACROGRAF 0.25MG CAP 1X10 at room temperature.

Benefits of TACROGRAF 0.25MG CAPSULE 10'SArrow

  • TACROGRAF 0.25MG CAPSULE 10'S is a medication that belongs to a class of drugs known as immunosuppressants. It functions by suppressing the activity of the immune system. Specifically, it inhibits the activation and proliferation of T-lymphocytes, which are crucial cells involved in the immune response. Furthermore, it also dampens the T-helper-cell-dependent B-cell response, further modulating the immune system's activity. Essentially, it works by attaching to a specific intracellular protein called FKBP-12. Upon binding, TACROGRAF 0.25MG CAPSULE 10'S forms a complex referred to as tacrolimus-FKBP. This complex then goes on to inhibit the action of calcineurin phosphatase, a critical enzyme involved in T-cell activation.
  • The inhibition of calcineurin phosphatase by the tacrolimus-FKBP complex disrupts the signaling pathways necessary for T-cell development and function. This ultimately leads to a reduction in the formation of functional T cells, effectively suppressing the overall immune response. By suppressing the immune system, TACROGRAF 0.25MG CAPSULE 10'S helps to prevent the body from attacking transplanted organs or tissues, making it a vital medication for individuals undergoing organ transplantation. It can also be used in the treatment of certain autoimmune disorders where the immune system mistakenly attacks the body's own tissues.
  • In simpler terms, TACROGRAF 0.25MG CAPSULE 10'S acts like a 'peacekeeper' within your body, preventing your immune system from launching attacks when it shouldn't. This is particularly important after an organ transplant, where the immune system might see the new organ as a foreign invader and try to reject it. By calming down the immune system, TACROGRAF 0.25MG CAPSULE 10'S helps ensure the transplanted organ survives and functions properly. It's a powerful medication that plays a critical role in preventing organ rejection and managing certain immune-related conditions.

How to use TACROGRAF 0.25MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 0.25MG CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take TACROGRAF 0.25MG CAPSULE 10'S exactly as prescribed by your doctor. Self-medication or altering the dosage without consulting your doctor can be harmful.
  • For optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. The capsule should be swallowed whole with a full glass of water. This ensures that the medication is released properly in your system.
  • To maximize the drug's absorption and minimize potential interactions with food, take TACROGRAF 0.25MG CAPSULE 10'S on an empty stomach. Ideally, consume it at least 1 hour before a meal or wait for 2 to 3 hours after eating before taking the capsule. Following these instructions carefully will help ensure you receive the full benefit of the medication.

FAQs

What if I missed a dose of TACROGRAF 0.25MG CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with TACROGRAF 0.25MG CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take TACROGRAF 0.25MG CAPSULE 10'S after a transplant?Arrow

The duration of TACROGRAF 0.25MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, TACROGRAF 0.25MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can TACROGRAF 0.25MG CAPSULE 10'S increase the risk of infections?Arrow

Yes, TACROGRAF 0.25MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can TACROGRAF 0.25MG CAPSULE 10'S affect kidney function?Arrow

TACROGRAF 0.25MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking TACROGRAF 0.25MG CAPSULE 10'S?Arrow

TACROGRAF 0.25MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

Does TACROGRAF 0.25MG CAPSULE 10'S interact with other drugs?Arrow

NULL interaction of TACROGRAF 0.25MG CAPSULE 10'S with other drungs

What advice should I follow while taking TACROGRAF 0.25MG CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using TACROGRAF 0.25MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is TACROGRAF 0.25MG CAPSULE 10'S made of?Arrow

TACROLIMUS is molecule/combination used for making TACROGRAF 0.25MG CAPSULE 10'S.

What is the use of TACROGRAF 0.25MG CAPSULE 10'S in Nephrology?Arrow

Nephrology is a condition for which TACROGRAF 0.25MG CAPSULE 10'S is presecribed.

What is the use of TACROGRAF 0.25MG CAPSULE 10'S in Infectious Disease?Arrow

Infectious Disease is a condition for which TACROGRAF 0.25MG CAPSULE 10'S is presecribed.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Good. Provides medicines at reasonable rates.

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All drugs available good service

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Reviewed on 23-01-2024

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(5/5)


Marketer / Manufacturer Details

BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

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India

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TACROGRAF 0.25MG CAPSULE 10'S

TACROGRAF 0.25MG CAPSULE 10'S

MRP

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₹135

26.63 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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