TAKFA 0.25MG CAPSULE 10'S
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TAKFA 0.25MG CAPSULE 10'STAKFA 0.25MG CAPSULE 10'STAKFA 0.25MG CAPSULE 10'S
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TAKFA 0.25MG CAPSULE 10'S

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TAKFA 0.25MG CAPSULE 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

₹

159

₹130

18.24 % OFF

₹13 Only /

CAPSULE

10

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Product DetailsArrow

About TAKFA 0.25MG CAPSULE 10'S

  • TAKFA 0.25MG CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant belonging to the class of medications called calcineurin inhibitors. This capsule is used in conjunction with other medications to prevent organ transplant rejection in individuals who have received liver, kidney, heart, or other organ transplants. It is also prescribed to control your body’s immune response, helping it to accept the transplanted organ. This medication works by suppressing the activity of certain immune cells, which reduces the risk of the body attacking the new organ.
  • Before taking TAKFA 0.25MG CAPSULE 10'S, inform your doctor if you are allergic to tacrolimus or any other components of this medicine. Also, report any allergies you have to any antibiotic group. It is crucial to inform your doctor if you have or have had any liver or heart disease before starting treatment with this medication. Seek immediate medical attention and notify your physician if you experience symptoms such as fever, unexplained bruising under the skin (appearing as red dots), unusual tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision disturbances, or seizures after taking this medicine. These symptoms could indicate serious side effects.
  • While taking TAKFA 0.25MG CAPSULE 10'S, it is important to limit your exposure to sunlight and UV light by wearing protective clothing and using sunscreen with a high sun protection factor. This is due to the potential risk of malignant skin changes associated with immunosuppressive therapy. Be aware that this medicine may cause diarrhea; if you experience diarrhea for more than a day, inform your physician. Furthermore, if you need to receive any vaccinations, consult your doctor beforehand to ensure it is safe and appropriate for you.
  • It's also vital to maintain good communication with your healthcare provider regarding any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with TAKFA 0.25MG CAPSULE 10'S. Regular monitoring of your blood levels and kidney function may be necessary while you are on this medication to ensure its effectiveness and safety. Adhering to your doctor's instructions and attending scheduled check-ups are essential for managing your health while taking immunosuppressants.

Uses of TAKFA 0.25MG CAPSULE 10'S

  • Prevent organ transplant rejections. After an organ transplant, the body may try to reject the new organ. This medicine helps lower the chance of rejection.

How TAKFA 0.25MG CAPSULE 10'S Works

  • TAKFA 0.25MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
  • TAKFA 0.25MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, TAKFA 0.25MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, TAKFA 0.25MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of TAKFA 0.25MG CAPSULE 10'S in skin disorders is not fully understood.

Side Effects of TAKFA 0.25MG CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. For TAKFA 0.25MG CAPSULE 10'S, common side effects include swelling in the arm or leg, hair loss, itchy skin, constipation, diarrhea, nausea, vomiting, anemia, headache, and cough. Serious side effects include increased or decreased heartbeats, GI bleeding, liver injury, seizure, acute kidney failure, and lung infection or respiratory problems.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for TAKFA 0.25MG CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, TAKFA 0.25MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of TAKFA 0.25MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of TAKFA 0.25MG CAPSULE 10'S.
  • Never attempt to alter the prescribed dosage or treatment schedule without consulting your healthcare provider. Doing so can negatively impact the effectiveness of the medication and potentially lead to unwanted side effects.
  • For optimal absorption and effectiveness, TAKFA 0.25MG CAPSULE 10'S should be taken on an empty stomach. This typically means consuming the capsule at least one hour before a meal or waiting two to three hours after eating.
  • Ensure you swallow the capsule whole with a full glass of water. Avoid opening, crushing, breaking, or chewing the capsules, as this could interfere with the intended release of the medication and affect its efficacy.
  • If you have any concerns or questions about how to properly take TAKFA 0.25MG CAPSULE 10'S, please do not hesitate to consult with your doctor or pharmacist. They can provide personalized guidance and address any uncertainties you may have.

How to store TAKFA 0.25MG CAPSULE 10'S?Arrow

  • Keep TAKFA 0.25MG CAP 1X10 away from the reach of children and pets.
  • Store TAKFA 0.25MG CAP 1X10 at room temperature.

Benefits of TAKFA 0.25MG CAPSULE 10'SArrow

  • TAKFA 0.25MG CAPSULE 10'S is a medication that helps to suppress the immune system. It achieves this by targeting and inhibiting the activation and proliferation of T-lymphocytes, which are crucial cells in the immune response. It also hinders the T-helper-cell-dependent B-cell response, further dampening the immune system's activity. The drug functions by binding to an intracellular protein known as FKBP-12, forming a complex called tacrolimus-FKBP. This complex then inhibits calcineurin phosphatase, a critical enzyme involved in T-cell activation. By blocking calcineurin, TAKFA 0.25MG CAPSULE 10'S effectively prevents the formation of T cells and, as a result, suppresses the overall immune response. This action makes it valuable in preventing organ rejection after transplants and in managing certain autoimmune disorders where an overactive immune system attacks the body's own tissues.
  • In simpler terms, TAKFA 0.25MG CAPSULE 10'S acts like a brake on your immune system. Imagine your immune system is a powerful army protecting your body. Sometimes, this army can get confused and start attacking your own organs or tissues. TAKFA 0.25MG CAPSULE 10'S steps in to calm down this army, preventing it from causing harm. It does this by interfering with the signals that tell the army to mobilize and attack, specifically targeting the T cells and B cells that are responsible for the immune response.
  • This immunosuppressive action makes TAKFA 0.25MG CAPSULE 10'S essential for individuals who have undergone organ transplantation. After a transplant, the body's immune system naturally recognizes the new organ as foreign and attempts to reject it. TAKFA 0.25MG CAPSULE 10'S helps to prevent this rejection by suppressing the immune response, allowing the transplanted organ to function properly. It's also used to treat certain autoimmune diseases, such as rheumatoid arthritis or psoriasis, where the immune system is overactive and attacks healthy tissues.

How to use TAKFA 0.25MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take TAKFA 0.25MG CAPSULE 10'S exactly as prescribed by your doctor. Do not attempt to open, break, crush, or chew the capsules, as this could affect how the medication is absorbed.
  • Swallow the capsule whole with a full glass of water to ensure it goes down smoothly and to aid in its absorption. For optimal effectiveness, take these capsules on an empty stomach. This means consuming them either at least 1 hour before a meal or waiting 2 to 3 hours after eating.
  • Adhering to these guidelines will help ensure that the medication works as effectively as possible. If you have any questions or concerns about how to take TAKFA 0.25MG CAPSULE 10'S, please consult with your doctor or pharmacist for further clarification.

FAQs

What if I missed a dose of TAKFA 0.25MG CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with TAKFA 0.25MG CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take TAKFA 0.25MG CAPSULE 10'S after a transplant?Arrow

The duration of TAKFA 0.25MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, TAKFA 0.25MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can TAKFA 0.25MG CAPSULE 10'S increase the risk of infections?Arrow

Yes, TAKFA 0.25MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can TAKFA 0.25MG CAPSULE 10'S affect kidney function?Arrow

TAKFA 0.25MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking TAKFA 0.25MG CAPSULE 10'S?Arrow

TAKFA 0.25MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important. 

What are the interactions of TAKFA 0.25MG CAPSULE 10'S with other drugs?Arrow

There are no known negative interactions of TAKFA 0.25MG CAPSULE 10'S with other drugs.

What advice should I follow while taking TAKFA 0.25MG CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using TAKFA 0.25MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is TAKFA 0.25MG CAPSULE 10'S made of?Arrow

TACROLIMUS is the molecule/combination used for making TAKFA 0.25MG CAPSULE 10'S.

For which conditions is TAKFA 0.25MG CAPSULE 10'S typically prescribed?Arrow

TAKFA 0.25MG CAPSULE 10'S is typically prescribed for conditions related to Nephrology and Infectious Diseases.

Can TAKFA 0.25MG CAPSULE 10'S help with Infectious Diseases?Arrow

TAKFA 0.25MG CAPSULE 10'S may be used in the treatment of Infectious Diseases.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

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India

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