TOZAAR AT TABLET 15'S

How TOZAAR AT TABLET 15'S Works

• TOZAAR AT TABLET 15'S is a combination medication containing two active ingredients: Losartan and Amlodipine. These components work synergistically to effectively lower blood pressure and reduce the risk of cardiovascular events. Understanding how each ingredient functions is crucial to appreciating the overall mechanism of action of TOZAAR AT.
• Losartan belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). Angiotensin II is a naturally occurring hormone in the body that causes blood vessels to constrict, leading to increased blood pressure. Losartan works by selectively blocking the binding of angiotensin II to its receptors, particularly the AT1 receptors found in blood vessels and other tissues. By blocking these receptors, Losartan prevents angiotensin II from exerting its vasoconstrictive effects. This results in vasodilation, or the widening of blood vessels, which in turn lowers blood pressure. Losartan also helps to reduce the release of aldosterone, a hormone that promotes sodium and water retention by the kidneys. By reducing aldosterone levels, Losartan further contributes to lowering blood pressure and reducing fluid overload.
• Amlodipine, on the other hand, is a calcium channel blocker. Calcium plays a vital role in muscle contraction, including the contraction of smooth muscle cells in the walls of blood vessels. Amlodipine works by blocking the entry of calcium into these smooth muscle cells. This reduces the force of contraction and causes the blood vessels to relax and dilate. This vasodilation effect of amlodipine lowers blood pressure and improves blood flow to the heart. Amlodipine primarily affects the arteries and arterioles, the smaller blood vessels that regulate blood flow. By relaxing these vessels, Amlodipine reduces the afterload on the heart, which is the resistance the heart must pump against to eject blood.
• The combination of Losartan and Amlodipine in TOZAAR AT provides a dual mechanism of action to effectively manage hypertension. Losartan blocks the effects of angiotensin II, while Amlodipine blocks calcium channels. This synergistic effect results in a greater reduction in blood pressure than either drug alone. The combination also addresses different pathways involved in blood pressure regulation, providing comprehensive control. By lowering blood pressure, TOZAAR AT helps to reduce the risk of serious cardiovascular events such as stroke, heart attack, and kidney disease. It is essential to take TOZAAR AT exactly as prescribed by your doctor and to follow their instructions regarding lifestyle modifications, such as diet and exercise, to further optimize blood pressure control.

Common side effects of TOZAAR AT Tablet may include dizziness, headache, fatigue, nausea, abdominal pain, cough, and upper respiratory tract infections. Less common but potentially serious side effects can include allergic reactions (rash, itching, swelling), kidney problems (changes in urine output), high potassium levels (muscle weakness, irregular heartbeat), low blood pressure (fainting), and muscle pain or weakness (rhabdomyolysis). It's crucial to consult your doctor if you experience any unusual or severe symptoms while taking this medication.

• If you miss a dose of TOZAAR AT TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TOZAAR AT TAB 1X15 away from the reach of children and pets.
• Store TOZAAR AT TAB 1X15 at room temperature.

• Take TOZAAR AT TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood pressure control and potentially lead to adverse health outcomes.
• Monitor your blood pressure regularly while taking TOZAAR AT TABLET 15'S. Keep a log of your readings and share it with your doctor during appointments. This helps in assessing the effectiveness of the medication and making necessary adjustments.
• Be aware of potential side effects, such as dizziness, lightheadedness, or cough. If these or any other unusual symptoms occur, contact your doctor promptly. Do not drive or operate heavy machinery if you feel dizzy or lightheaded.
• Maintain a healthy lifestyle while taking TOZAAR AT TABLET 15'S. This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity, and avoiding excessive alcohol consumption. These measures can enhance the medication's effectiveness and improve your overall cardiovascular health.
• Inform your doctor about all other medications, supplements, and herbal products you are taking, especially those that can affect blood pressure, such as NSAIDs (nonsteroidal anti-inflammatory drugs). This helps prevent potential drug interactions and ensures your safety.

• TOZAAR AT TABLET 15'S can be taken with or without food. Food does not significantly affect the absorption of the medication. However, it's advisable to maintain a consistent diet while on this medication to ensure stable blood pressure and overall health. Consult your doctor for specific dietary recommendations.