UNITREXATE 500 INJECTION
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UNITREXATE 500 INJECTION
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UNITREXATE 500 INJECTION

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UNITREXATE 500 INJECTION

By UNITED BIOTECH PVT LTD

MRP

657

₹591.3

10 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About UNITREXATE 500 INJECTION

  • UNITREXATE 500 INJECTION contains the active substance Methotrexate, functioning as an anti-metabolite and immunosuppressant. This medication is prescribed for the treatment of various cancers, including acute lymphocytic leukemia (ALL), meningeal leukemia, non-Hodgkin's lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer specifically in adult patients. Moreover, it serves as a treatment for severe psoriasis in adults, a skin condition characterized by the development of red, scaly patches on different areas of the body. It is also indicated for managing rheumatoid arthritis in adult patients, offering relief from inflammation and joint pain.
  • It is crucial to avoid UNITREXATE 500 INJECTION if you have a known allergy to methotrexate or any other component of this medicine. This medication is contraindicated in individuals with pre-existing kidney or liver problems, blood disorders, or a weakened immune system. It should not be used during pregnancy or breastfeeding. Immediately inform your physician if you experience any concerning symptoms such as spitting or coughing up blood, generalized muscle weakness, vision disturbances, or changes in thinking, memory, or orientation. It's important to note that this medicine may impair fertility, and therefore, avoiding pregnancy is recommended during treatment and for six months following the last dose.
  • Before initiating treatment with UNITREXATE 500 INJECTION, inform your doctor if you have a history of stomach ulcers, active infections, or mild kidney problems, and disclose any recent vaccinations you may have received. Due to the potential for serious side effects, even at low doses, regular follow-up appointments and routine laboratory tests are necessary as a precautionary measure. It is essential to avoid using this medicine if you are pregnant, breastfeeding, or planning to become pregnant. Discuss all medical conditions and medications with your healthcare provider to ensure safe and effective treatment.

Uses of UNITREXATE 500 INJECTION

  • To aid in the treatment of specific cancer types, providing a therapeutic intervention.
  • To assist in the management of severe psoriasis, alleviating symptoms and promoting skin health.
  • To help in the treatment of rheumatoid arthritis, reducing inflammation and joint pain.

Side Effects of UNITREXATE 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Hairloss
  • Photosensitivity
  • Rash
  • Diarrhea, Nausea and Vomiting
  • Decreased WBC and platelet count
  • Dizziness
  • Tiredness, fever, and shivering
  • Blurred vision
  • Severe allergic reactions
  • Spitting or coughing blood
  • Chest pain
  • Weakness on one side of the body
  • Muscle weakness

Safety Advice for UNITREXATE 500 INJECTIONArrow

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Pregnancy

UNSAFE

Do not use UNITREXATE 500 INJECTION during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.

Dosage of UNITREXATE 500 INJECTIONArrow

  • It is crucial to adhere strictly to your doctor's prescribed dosage of this medicine. The dose, frequency, and method of administration of UNITREXATE 500 INJECTION are determined by your physician, considering the specific condition being treated. This medication is administered either intravenously (directly into a vein) or intramuscularly (into a muscle).
  • It is imperative that you do not attempt to self-administer UNITREXATE 500 INJECTION. This injection requires specialized medical knowledge and sterile equipment to ensure safe and effective delivery. Improper administration can lead to serious complications and adverse effects.
  • Your healthcare provider will carefully calculate the appropriate dose based on factors such as your weight, overall health, and the severity of your condition. They will also monitor your response to the medication and adjust the dosage accordingly to achieve the best possible outcome. Always follow their instructions precisely and ask if anything is unclear.
  • Regular monitoring and follow-up appointments with your doctor are essential while receiving UNITREXATE 500 INJECTION. These appointments allow your doctor to assess your progress, monitor for any side effects, and make any necessary adjustments to your treatment plan. Do not miss any scheduled appointments.

How to store UNITREXATE 500 INJECTION?Arrow

  • Keep UNITREXATE 500MG INJ 20ML away from the reach of children and pets.
  • Store UNITREXATE 500MG INJ 20ML at room temperature.

Benefits of UNITREXATE 500 INJECTIONArrow

  • UNITREXATE 500 INJECTION is a medication that works by inhibiting dihydrofolic acid reductase, an enzyme crucial for cell growth and multiplication. This interference disrupts the synthesis of DNA, its repair mechanisms, and the process of cellular replication. Consequently, it has a significant impact on tissues with rapid cell turnover, including malignant cells, bone marrow, fetal cells, the lining of the mouth and intestines (buccal and intestinal mucosa), and cells of the urinary bladder. Because of this sensitivity, UNITREXATE 500 INJECTION is effective at slowing down the proliferation of cancer cells, hindering their spread to other parts of the body. In autoimmune diseases, it helps by suppressing the overactive immune system that is attacking the body's own tissues.
  • Furthermore, by targeting rapidly dividing cells, UNITREXATE 500 INJECTION can effectively manage conditions characterized by excessive cell growth. Its mechanism of action makes it a valuable tool in treating various types of cancer and managing autoimmune disorders where immune system suppression is necessary to alleviate symptoms and prevent further tissue damage.
  • The impact on DNA synthesis and repair highlights its potent effect on cellular processes, underscoring the importance of careful monitoring and management during treatment to minimize potential side effects and ensure optimal therapeutic outcomes.

How to use UNITREXATE 500 INJECTIONArrow

  • It is crucial to use this medicine exactly as your doctor has prescribed. The dosage, frequency, and route of administration will be determined by your physician based on the specific condition being treated. UNITREXATE 500 INJECTION is typically administered via injection, either directly into a vein (intravenously) or into a muscle (intramuscularly).
  • This medication should only be administered by a healthcare professional. It is essential that you do not attempt to self-administer this injection, as it requires specific training and expertise to ensure safe and effective delivery. Improper administration can lead to complications.
  • Your doctor will provide specific instructions regarding the timing and frequency of your injections. Be sure to follow these instructions carefully. If you have any questions or concerns about how the medication is being administered, or about the treatment plan in general, do not hesitate to ask your doctor or nurse for clarification. Understanding the process and adhering to the prescribed regimen are vital for achieving the best possible outcome from your treatment.

FAQs

What are the most common side effects of UNITREXATE 500 INJECTION?Arrow

The most common side effects of UNITREXATE 500 INJECTION are hair loss, photosensitivity, rash, diarrhea, nausea, vomiting, decreased WBC and platelet count, dizziness, tiredness, fever, shivering, and blurred vision. Inform your physician if these side effects persist for a longer period.

What to expect after taking UNITREXATE 500 INJECTION for ectopic pregnancy?Arrow

Some possible side effects after taking UNITREXATE 500 INJECTION include nausea, vomiting, abdominal cramping, skin rashes, indigestion, tiredness, lightheadedness, or dizziness. Consult your doctor if you have noticed any of these side effects.

How to boost the immune system while taking UNITREXATE 500 INJECTION?Arrow

Eating a well-balanced diet is important as taking all other prescribed medications, including vitamin supplements, getting adequate sleep, and staying hydrated. It can boost your immune system while taking UNITREXATE 500 INJECTION

Can I stop taking UNITREXATE 500 INJECTION?Arrow

Do not stop taking UNITREXATE 500 INJECTION without consulting your doctor. If stopped abruptly, this medicine may cause side effects.

How long can you take UNITREXATE 500 INJECTION?Arrow

Take this medicine as long as your healthcare professional prescribes it. Generally, this medicine will be prescribed until your disease condition gets resolved. Do not stop this medicine without consulting the doctor.

How do I know if UNITREXATE 500 INJECTION is working?Arrow

People taking this medicine can see improvement in 12 weeks. For some individuals, it may take longer to show the results based on their condition. Your physician will suggest you take regular blood tests and follow-ups to monitor the effectiveness of the therapy.

NULL interaction of UNITREXATE 500 INJECTION with other drungsArrow

UNITREXATE 500 INJECTION has no known significant interactions with other drugs. Always inform your doctor about all the medications, supplements, and herbal products you are taking.

What precautions should I take while using UNITREXATE 500 INJECTION?Arrow

Avoid getting vaccines while using this medicine. This drug can cause sun sensitivity, so use sunscreen when going outdoors. UNITREXATE 500 INJECTION affects male and female infertility; consult your doctor before initiating the treatment if this concerns you. Male patients with female partners with reproductive potential should use an effective form of birth control during the treatment and 3 months after the last dose. Do not consume alcohol while receiving this medicine because this may increase the risk of liver damage. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Inform your physician if you develop sores or white patches on your lips, mouth, or throat while using this medicine.

Why should alcohol not be consumed with UNITREXATE 500 INJECTION?Arrow

Consuming alcohol with UNITREXATE 500 INJECTION may increase the risk of liver damage.

What is UNITREXATE 500 INJECTION made of?Arrow

METHOTREXATE is molecule/combination used for making UNITREXATE 500 INJECTION.

For which ailments is UNITREXATE 500 INJECTION prescribed?Arrow

UNITREXATE 500 INJECTION is prescribed for ailments related to Rheumatology, Orthopaedics, and Gastroenterology.

References

Book Icon

Methotrexate tablet - Patient Information Leaflet (PIL) - (emc) [Internet]. www.medicines.org.uk.

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Hospira, Methotrexate Tablet, Food and drug administration. acess.fda.gov.

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Marketer / Manufacturer Details

UNITED BIOTECH PVT LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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