DAPAGLYN SM 100/500MG TABLET 10'S

How DAPAGLYN SM 100/500MG TABLET 10'S Works

• Dapaglyn SM 100/500mg Tablet is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: dapagliflozin and metformin. Each component works through distinct mechanisms to lower blood sugar levels and improve glycemic control.
• **Dapagliflozin's Mechanism of Action:** Dapagliflozin belongs to a class of drugs known as Sodium-Glucose Co-transporter 2 (SGLT2) inhibitors. The kidneys filter glucose from the blood, and SGLT2 proteins are responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits SGLT2 in the kidneys. By blocking SGLT2, dapagliflozin reduces the reabsorption of glucose, leading to excess glucose being excreted through urine. This reduces blood glucose levels. This mechanism is insulin-independent, meaning it works regardless of insulin availability or sensitivity, making it effective even in patients with insulin resistance or deficiency.
• **Metformin's Mechanism of Action:** Metformin is a biguanide that works primarily by decreasing glucose production in the liver. The liver is a major source of glucose, especially during fasting or between meals. Metformin inhibits hepatic gluconeogenesis, the process by which the liver produces glucose from non-carbohydrate sources. Metformin also enhances insulin sensitivity in peripheral tissues, such as muscle and fat. This allows cells to take up glucose more efficiently from the bloodstream, further reducing blood sugar levels. In addition, metformin slows down the absorption of glucose from the intestines, reducing the post-meal spike in blood sugar.
• **Synergistic Effect:** The combination of dapagliflozin and metformin provides a dual approach to managing blood sugar levels. Dapagliflozin reduces glucose reabsorption in the kidneys, while metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic effect results in more effective blood glucose control compared to either medication used alone. By targeting different pathways involved in glucose metabolism, Dapaglyn SM helps to lower both fasting and postprandial (after-meal) blood sugar levels.
• **Additional Benefits:** Besides lowering blood sugar, dapagliflozin has been shown to offer additional benefits, such as weight loss and blood pressure reduction. Metformin is known for its cardiovascular benefits. It is important to use Dapaglyn SM 100/500mg Tablet as part of a comprehensive diabetes management plan that includes diet and exercise.

Dapaglyn SM 100/500mg Tablet 10's may cause side effects, although not everyone experiences them. Common side effects may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Hypoglycemia (low blood sugar) when used with other diabetes medications, Genital yeast infections (both in men and women), Urinary tract infections. Less common but potentially serious side effects include: Diabetic ketoacidosis (symptoms may include nausea, vomiting, abdominal pain, excessive thirst, and rapid breathing), Kidney problems, Allergic reactions (rash, itching, swelling), Increased cholesterol levels, Vitamin B12 deficiency. This is not an exhaustive list, and it is important to consult with your doctor or pharmacist if you experience any unusual or persistent symptoms while taking this medication.

• If you miss a dose of DAPAGLYN SM 100/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep DAPAGLYN SM 100/500MG TAB 1X10 away from the reach of children and pets.
• Store DAPAGLYN SM 100/500MG TAB 1X10 at room temperature.

• **Take DAPAGLYN SM 100/500MG TABLET as prescribed by your doctor.** Adhere strictly to the dosage and timing instructions provided. Do not self-adjust the dose or discontinue the medication without consulting your healthcare provider, as this can affect blood sugar control.
• **Monitor your blood sugar levels regularly.** DAPAGLYN SM helps control blood sugar, but regular monitoring is essential to ensure it's working effectively. Keep a log of your readings to share with your doctor during check-ups.
• **Stay hydrated.** Drink plenty of water throughout the day. DAPAGLYN SM can increase the risk of dehydration, so maintaining adequate fluid intake is important, especially during exercise or hot weather.
• **Be aware of potential side effects.** Common side effects may include urinary tract infections, yeast infections, and increased urination. Contact your doctor if you experience persistent or bothersome side effects. Be particularly vigilant for signs of ketoacidosis, a serious complication, such as nausea, vomiting, abdominal pain, and confusion.
• **Maintain a healthy lifestyle.** DAPAGLYN SM works best when combined with a balanced diet and regular exercise. Follow a meal plan recommended by your doctor or a registered dietitian, and aim for at least 30 minutes of moderate-intensity exercise most days of the week. Avoid excessive alcohol consumption, as it can interfere with blood sugar control.
• **Store DAPAGLYN SM properly.** Keep the tablets in a cool, dry place, away from direct sunlight and moisture. Ensure that the medication is out of reach of children and pets.
• **Inform your doctor about all medications and supplements you're taking.** DAPAGLYN SM can interact with other medications, including over-the-counter drugs and herbal supplements. Providing a complete list of your medications helps prevent potential interactions.
• **Understand the signs of hypoglycemia (low blood sugar).** Although less common with DAPAGLYN SM alone, be aware of symptoms such as shakiness, sweating, dizziness, and confusion. Keep a source of fast-acting sugar (glucose tablets or juice) on hand to treat hypoglycemia if it occurs.
• **Attend regular check-ups with your doctor.** Routine visits allow your doctor to monitor your blood sugar control, kidney function, and overall health. These visits are essential for making any necessary adjustments to your treatment plan.
• **Be cautious when driving or operating machinery.** If DAPAGLYN SM is used in combination with other medications that can cause hypoglycemia, take precautions to avoid low blood sugar episodes while driving or operating machinery.

• Dapaglyn SM 100/500mg Tablet 10's can be taken with or without food. However, it is important to take it at a consistent time each day to maintain steady blood sugar levels. There are no specific food restrictions while taking this medication, but it is generally advisable to follow a healthy and balanced diet. Consult your doctor or pharmacist for personalized advice regarding your diet while on this medication.