SITAXA DM 10/100/500MG TABLET 10'S

How SITAXA DM 10/100/500MG TABLET 10'S Works

• SITAXA DM 10/100/500MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Sitagliptin, Metformin, and Dapagliflozin, each working through different mechanisms to achieve comprehensive glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. They stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help lower blood glucose. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This enhances insulin secretion when blood sugar is high and reduces glucagon secretion, ultimately leading to improved blood sugar control. It works in a glucose-dependent manner, meaning it primarily affects insulin release when glucose levels are elevated, reducing the risk of hypoglycemia.
• Metformin is a biguanide that works primarily by decreasing glucose production in the liver. The liver is a major source of glucose in the body, and in people with type 2 diabetes, the liver often produces too much glucose. Metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the formation of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to use glucose more effectively. It also slows down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effects. Metformin does not stimulate insulin release, so it carries a low risk of causing hypoglycemia when used alone.
• Dapagliflozin is an SGLT2 inhibitor (sodium-glucose cotransporter 2 inhibitor). SGLT2 is a protein found in the kidneys that is responsible for reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, Dapagliflozin prevents the kidneys from reabsorbing glucose, causing more glucose to be excreted in the urine. This reduces blood sugar levels and can also lead to weight loss as calories are lost through the urine. Additionally, Dapagliflozin has been shown to have cardiovascular benefits in some patients.
• In summary, SITAXA DM works through three complementary mechanisms: Sitagliptin enhances incretin activity to increase insulin release and decrease glucagon secretion, Metformin reduces glucose production in the liver and improves insulin sensitivity, and Dapagliflozin increases glucose excretion in the urine. This combination provides a comprehensive approach to managing blood sugar levels in type 2 diabetes.
• It is important to note that SITAXA DM should be used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring of blood sugar levels. Patients should follow their doctor's instructions carefully and be aware of potential side effects.

Common side effects of SITAXA DM 10/100/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, skin rash, itching, headache, dizziness, and hypoglycemia (low blood sugar). Less common but potentially serious side effects can include pancreatitis, severe allergic reactions (anaphylaxis), liver problems, kidney problems, lactic acidosis, and nerve damage (peripheral neuropathy). Other possible side effects are constipation, flatulence, dyspepsia, weakness, fatigue, upper respiratory tract infection, edema, blurred vision, and macrocytic anemia. This is not an exhaustive list; consult your doctor for more information.

• If you miss a dose of SITAXA DM 10/100/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAXA DM 10/100/500MG TAB 1X10 away from the reach of children and pets.
• Store SITAXA DM 10/100/500MG TAB 1X10 at room temperature.

• Take SITAXA DM 10/100/500MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this could affect your blood sugar control.
• It is best to take SITAXA DM 10/100/500MG TABLET 10'S with food to minimize the risk of gastrointestinal side effects such as nausea, vomiting, or diarrhea. Consistent timing with meals can also help maintain stable blood sugar levels.
• Regularly monitor your blood sugar levels as directed by your doctor while taking SITAXA DM 10/100/500MG TABLET 10'S. Keep a record of your readings and share them with your healthcare provider during your appointments. This helps in assessing the effectiveness of the medication and making necessary adjustments to your treatment plan.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting SITAXA DM 10/100/500MG TABLET 10'S. Certain medications can interact with this medicine, affecting its efficacy or increasing the risk of side effects. Be particularly cautious about medications that affect blood sugar levels, such as insulin or other oral antidiabetic drugs.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. These lifestyle modifications can significantly enhance the effectiveness of SITAXA DM 10/100/500MG TABLET 10'S in managing your blood sugar levels. Consult with a registered dietitian or certified diabetes educator for personalized guidance.
• Stay hydrated by drinking plenty of water throughout the day. Proper hydration is important for overall health and can also help regulate blood sugar levels. Avoid sugary drinks, as they can lead to rapid spikes in blood sugar.
• Be aware of the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Hypoglycemia symptoms may include shakiness, sweating, confusion, and dizziness, while hyperglycemia symptoms may include increased thirst, frequent urination, and blurred vision. Know how to manage these conditions and inform your family and friends about what to do in case of an emergency.
• Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are essential for monitoring your overall health and ensuring that SITAXA DM 10/100/500MG TABLET 10'S is effectively managing your diabetes.
• Store SITAXA DM 10/100/500MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets.
• If you experience any unusual or severe side effects while taking SITAXA DM 10/100/500MG TABLET 10'S, such as persistent nausea, abdominal pain, or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention.

• SITAXA DM 10/100/500MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood sugar levels. Consult your doctor for specific dietary recommendations while on this medication. Generally, maintaining a healthy and balanced diet is recommended.