DAPALEX SM 10/100/500MG TABLET 10'S

How DAPALEX SM 10/100/500MG TABLET 10'S Works

• DAPALEX SM 10/100/500MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Dapagliflozin, Sitagliptin, and Metformin. Each component works through a distinct mechanism to achieve comprehensive glycemic control.
• Dapagliflozin belongs to a class of drugs known as Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. The kidneys filter glucose from the blood, and SGLT2 is responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin inhibits SGLT2, preventing glucose reabsorption. This causes excess glucose to be excreted in the urine, effectively lowering blood sugar levels. This process is also associated with modest weight loss and blood pressure reduction in some individuals.
• Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released from the gut in response to food intake. They stimulate insulin release from the pancreas and reduce glucagon secretion from the liver. By inhibiting DPP-4, Sitagliptin increases the levels of active incretins in the body. This leads to enhanced insulin secretion (when blood sugar is high) and decreased glucagon secretion, both contributing to lower blood glucose levels.
• Metformin is a biguanide and works primarily by reducing glucose production in the liver. It also enhances insulin sensitivity in muscle tissue, allowing cells to utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines. Unlike some other diabetes medications, Metformin does not typically cause weight gain and may even promote modest weight loss.
• In combination, these three medications address different aspects of glucose regulation. Dapagliflozin reduces glucose reabsorption in the kidneys, Sitagliptin enhances insulin secretion and reduces glucagon secretion, and Metformin reduces hepatic glucose production and improves insulin sensitivity. This multi-pronged approach helps to effectively lower and maintain blood sugar levels in people with type 2 diabetes. It's important to take DAPALEX SM 10/100/500MG TABLET 10'S as prescribed by your doctor, along with lifestyle modifications like diet and exercise, for optimal blood sugar control.

DAPALEX SM 10/100/500MG TABLET 10'S may cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and constipation. Some patients might experience dizziness, headache, fatigue, and weakness. It can also cause hypoglycemia (low blood sugar), particularly when taken with other diabetes medications. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), liver problems (yellowing of the skin or eyes, dark urine), kidney problems, lactic acidosis (muscle pain, rapid breathing, stomach pain), and vitamin B12 deficiency. Contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of DAPALEX SM 10/100/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DAPALEX SM 10/100/500MG TAB 1X10 away from the reach of children and pets.
• Store DAPALEX SM 10/100/500MG TAB 1X10 at room temperature.

• Take DAPALEX SM exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, but your doctor will determine the best schedule for you based on your condition and other medications.
• DAPALEX SM is usually taken with food to help prevent stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body.
• It is important to monitor your blood sugar levels regularly while taking DAPALEX SM, especially if you are also taking other medications for diabetes. Keep a record of your blood sugar readings and share them with your doctor during your regular check-ups. This will help your doctor adjust your treatment plan as needed.
• Be aware of the potential side effects of DAPALEX SM, such as nausea, diarrhea, headache, or dizziness. If these side effects become severe or persistent, contact your doctor immediately. In rare cases, this medication can cause more serious side effects like lactic acidosis or kidney problems, so seek immediate medical attention if you experience symptoms like muscle pain, weakness, or difficulty breathing.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting DAPALEX SM. Certain medications can interact with DAPALEX SM, affecting its effectiveness or increasing the risk of side effects. This includes other diabetes medications, blood pressure medications, and certain antibiotics.
• Stay hydrated by drinking plenty of water throughout the day, especially when taking DAPALEX SM. This helps support kidney function and can reduce the risk of certain side effects. Avoid excessive alcohol consumption, as it can interfere with blood sugar control and increase the risk of adverse effects.
• Follow a healthy diet and exercise regularly while taking DAPALEX SM. This will help improve your blood sugar control and overall health. Your doctor or a registered dietitian can provide guidance on creating a suitable meal plan and exercise routine.
• Store DAPALEX SM at room temperature away from moisture and heat. Keep the medication in its original container and out of reach of children. Do not use the medication if it is expired or shows signs of damage.

• DAPALEX SM 10/100/500MG TABLET 10'S is generally taken orally with or without food. However, it is important to follow your doctor's instructions regarding when and how to take this medication. Consistent timing each day will help maintain steady levels of the drug in your body.
• If you experience stomach upset, taking it with food may help.
• Avoid excessive alcohol consumption while taking DAPALEX SM as it may increase the risk of side effects, such as low blood sugar (hypoglycemia) or liver problems. Discuss alcohol consumption with your doctor.