PREGABA NT 10MG TABLET 10'S

How PREGABA NT 10MG TABLET 10'S Works

• PREGABA NT 10MG TABLET 10'S is a combination medicine used to treat neuropathic pain. It works by modulating calcium channel activity and increasing the levels of certain neurotransmitters in the brain. The medicine contains Pregabalin and Nortriptyline.
• Pregabalin, an active ingredient, is an anticonvulsant and analgesic. It binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin reduces the influx of calcium into nerve terminals. This action inhibits the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. By reducing the release of these neurotransmitters, Pregabalin helps to alleviate pain signals and reduce nerve excitability, which is beneficial in conditions like neuropathic pain and fibromyalgia.
• Nortriptyline, another active ingredient, is a tricyclic antidepressant. It primarily works by inhibiting the reuptake of norepinephrine and, to a lesser extent, serotonin in the synaptic cleft. This action increases the concentration of these neurotransmitters in the synaptic space, allowing them to bind to their receptors for a more extended period. By increasing the levels of norepinephrine and serotonin, Nortriptyline can help to modulate pain pathways and improve mood. It also possesses anticholinergic properties, which can contribute to its therapeutic effects in certain pain conditions.
• The combination of Pregabalin and Nortriptyline offers a synergistic effect in managing neuropathic pain. Pregabalin addresses the neuronal hyperexcitability and neurotransmitter release, while Nortriptyline modulates the pain pathways and enhances mood. This dual action can provide more effective pain relief and improve the overall quality of life for individuals suffering from neuropathic pain. The medicine effectively reduces pain signals sent by damaged nerves, providing relief from the shooting, burning, or aching sensations associated with nerve pain.
• In summary, PREGABA NT 10MG TABLET 10'S works through the combined actions of Pregabalin and Nortriptyline. Pregabalin reduces the release of excitatory neurotransmitters by binding to calcium channels, while Nortriptyline increases the levels of norepinephrine and serotonin by inhibiting their reuptake. Together, they modulate pain pathways, reduce nerve excitability, and improve mood, leading to effective relief from neuropathic pain.

Common side effects of PREGABA NT 10MG TABLET may include: Dizziness, Sleepiness, Tiredness, Uncoordinated body movements. Other possible side effects are: Blurred vision, Increased appetite, Weight gain, Memory problems, Difficulty in concentration, Dryness in mouth, Increased sweating, Muscle pain, Vertigo, Decreased libido, Erectile dysfunction, Tremor, Peripheral edema (swelling of extremities). It can also cause mood changes like feeling depressed, anxious or irritable. In rare cases, some patients may experience suicidal thoughts. If you experience any of these side effects or any other unusual symptoms, consult your doctor immediately.

• If you miss a dose of PREGABA NT 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGABA NT 10MG TAB 1X10 away from the reach of children and pets.
• Store PREGABA NT 10MG TAB 1X10 at room temperature.

• Take PREGABA NT 10MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your physician. Sudden discontinuation can lead to withdrawal symptoms.
• PREGABA NT 10MG TABLET 10'S can cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how this medicine affects you. Be cautious when performing activities requiring alertness.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking. PREGABA NT 10MG TABLET 10'S can interact with other drugs, potentially altering their effects or increasing the risk of side effects. Pay special attention to medications that also cause drowsiness.
• If you experience any concerning side effects such as persistent nausea, vomiting, severe dizziness, swelling, vision changes, or unusual mood changes, contact your doctor immediately. Do not ignore or self-treat these symptoms, as they could indicate a serious problem.
• Store PREGABA NT 10MG TABLET 10'S at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Properly dispose of any unused or expired medication according to local regulations. Never share your medicine with others, even if they have similar symptoms.

• PREGABA NT 10MG TABLET 10'S can be taken with or without food. There are no specific food restrictions while taking this medication. However, it is always advisable to maintain a consistent dietary pattern.