PREGADOC NT TABLET 10'S

How PREGADOC NT TABLET 10'S Works

• PREGADOC NT Tablet 10's is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes pain due to damaged or malfunctioning nerves. It is caused by injury or damage to nerves and other parts of the nervous system. This damage interferes with the ability of nerves to send signals to the brain and spinal cord. PREGADOC NT Tablet 10's contains Pregabalin and Nortriptyline. Pregabalin is an alpha-2-delta ligand that decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and norepinephrine) that stop the movement of pain signals in the brain.
• Pregabalin, an active ingredient of PREGADOC NT, is structurally related to GABA (gamma-aminobutyric acid), a naturally occurring inhibitory neurotransmitter. Pregabalin binds to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in the central nervous system. This binding decreases the release of excitatory neurotransmitters, which reduces neuronal excitability and, consequently, neuropathic pain. By modulating calcium channel activity at nerve terminals, Pregabalin effectively calms overactive nerves, providing relief from the stabbing, burning, and shooting pains associated with nerve damage.
• Nortriptyline, a tricyclic antidepressant, works through a dual mechanism to alleviate neuropathic pain. Firstly, it inhibits the reuptake of serotonin and norepinephrine, two neurotransmitters that play a crucial role in mood regulation and pain modulation. By preventing their reabsorption, Nortriptyline increases the concentration of these neurotransmitters in the synaptic cleft (the space between nerve cells), enhancing their ability to dampen pain signals. Secondly, Nortriptyline has direct effects on pain pathways, helping to reduce the overall perception of pain. The combined action of increasing neurotransmitter levels and directly influencing pain pathways makes Nortriptyline an effective component in managing neuropathic pain.

Common side effects of Pregadoc NT Tablet may include: Dizziness, Sleepiness, Vomiting, Nausea, Difficulty in urination, Blurred vision, Dryness in mouth, Uncoordinated body movements. Less common or rare side effects may include: Peripheral edema (swelling of arms and legs), Weight gain, Confusion, Decreased libido, Erectile dysfunction, Memory impairment, Difficulty in concentration, Abnormal dreams, Visual disturbances, Muscle pain or cramps, Weakness, Tremors, Speech disorder, Changes in taste, Increased sweating, Palpitations, Orthostatic hypotension (decrease in blood pressure on standing), Allergic reactions (rash, itching, hives), Serotonin syndrome (symptoms may include high fever, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea).

• If you miss a dose of PREGADOC NT TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGADOC NT TAB 1X10 away from the reach of children and pets.
• Store PREGADOC NT TAB 1X10 at room temperature.

• Take PREGADOC NT TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen optimizes its effectiveness in managing neuropathic pain and associated conditions.
• Be mindful of potential side effects. Common side effects may include dizziness, drowsiness, nausea, or peripheral edema. If you experience persistent or bothersome side effects, promptly inform your healthcare provider. They can provide guidance on managing these effects or adjust your treatment plan if necessary.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Drug interactions can affect how PREGADOC NT TABLET 10'S works or increase the risk of side effects. A complete medication history helps your doctor ensure safe and effective treatment.
• Avoid alcohol consumption while taking PREGADOC NT TABLET 10'S. Alcohol can potentiate the sedative effects of the medication, leading to increased drowsiness, impaired coordination, and potentially dangerous interactions. Combining alcohol and PREGADOC NT TABLET 10'S is generally not recommended.
• Store PREGADOC NT TABLET 10'S in a safe place, away from direct sunlight, heat, and moisture. Keep the medication out of reach of children and pets. Proper storage helps maintain the drug's stability and effectiveness. If you have any unused medication, dispose of it properly according to local regulations.

• PREGADOC NT TABLET 10'S may be taken with or without food, but it is important to take it at a consistent time each day to maintain a steady level of medication in your body.
• Avoid alcohol consumption while taking PREGADOC NT TABLET 10'S, as it can increase the risk of side effects such as drowsiness and dizziness.
• There are no specific food restrictions while taking PREGADOC NT TABLET 10'S, but it's generally advisable to maintain a healthy and balanced diet.