AMIGRAF 1.0 CAPSULE 10'S
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AMIGRAF 1.0 CAPSULE 10'S
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AMIGRAF 1.0 CAPSULE 10'S

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AMIGRAF 1.0 CAPSULE 10'S

By BIOKINDLE LIFESCIENCES PRIVATE LIMITED

MRP

₹

407.81

₹346.64

15 % OFF

₹34.66 Only /

CAPSULE

10

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About AMIGRAF 1.0 CAPSULE 10'S

  • AMIGRAF 1.0 CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ.
  • Tacrolimus, the active component of AMIGRAF 1.0 CAPSULE 10'S, works by suppressing the activity of certain immune cells, such as T-cells, which are responsible for attacking foreign substances in the body, including transplanted organs. By inhibiting these cells, tacrolimus helps prevent the recipient's immune system from rejecting the new organ.
  • Do not take AMIGRAF 1.0 CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
  • It is crucial to take precautions while using AMIGRAF 1.0 CAPSULE 10'S. Limit exposure to sunlight and UV light while consuming AMIGRAF 1.0 CAPSULE 10'S by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them.
  • Regular monitoring by your healthcare provider is essential while taking AMIGRAF 1.0 CAPSULE 10'S. Blood tests will be conducted to check the levels of tacrolimus in your body and to monitor kidney and liver function. Dosage adjustments may be necessary based on these results. Be sure to attend all scheduled appointments and promptly report any new or worsening symptoms to your doctor.
  • Always take AMIGRAF 1.0 CAPSULE 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider. Consistency in taking the medication is key to preventing organ rejection and maintaining the health of your transplanted organ.

Uses of AMIGRAF 1.0 CAPSULE 10'S

  • Prevent organ transplant rejections. Reduces the likelihood of the body rejecting the transplanted organ after the transplant procedure.

Side Effects of AMIGRAF 1.0 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for AMIGRAF 1.0 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, AMIGRAF 1.0 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of AMIGRAF 1.0 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with AMIGRAF 1.0 CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to strictly adhere to your doctor's instructions regarding the use of this medication.
  • Always take AMIGRAF 1.0 CAPSULE 10'S exactly as prescribed by your healthcare provider. Deviating from the prescribed dosage or schedule can negatively impact the effectiveness of the treatment.
  • To ensure optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. Swallow the capsule whole with a full glass of water. This helps to deliver the medication to the appropriate site in your digestive system.
  • For best results, take AMIGRAF 1.0 CAPSULE 10'S on an empty stomach, which means either at least one hour before a meal or two to three hours after eating. This timing helps minimize potential interactions with food that could affect the drug's absorption. If you have any concerns or experience any side effects, promptly consult your doctor.

How to store AMIGRAF 1.0 CAPSULE 10'S?Arrow

  • Keep AMIGRAF 1MG CAP 1X10 away from the reach of children and pets.
  • Store AMIGRAF 1MG CAP 1X10 at room temperature.

Benefits of AMIGRAF 1.0 CAPSULE 10'SArrow

  • AMIGRAF 1.0 CAPSULE 10'S works by suppressing the body's immune system. It achieves this by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes. T-lymphocytes are crucial components of the immune system, and by inhibiting their activity, AMIGRAF 1.0 CAPSULE 10'S prevents the immune system from attacking the body's own tissues.
  • The medication's mechanism involves binding to an intracellular protein known as FKBP-12. This binding results in the formation of a complex called tacrolimus-FKBP. This complex then inhibits the activity of calcineurin phosphatase, an enzyme essential for T-cell activation. By blocking calcineurin, AMIGRAF 1.0 CAPSULE 10'S effectively disrupts the signaling pathways that lead to T-cell activation and the subsequent immune response.
  • Furthermore, AMIGRAF 1.0 CAPSULE 10'S also suppresses the response of B-cells that are dependent on T-helper cells. B-cells are responsible for producing antibodies, and their activity is often stimulated by T-helper cells. By inhibiting this interaction, AMIGRAF 1.0 CAPSULE 10'S further reduces the overall immune response, making it effective in preventing organ rejection after transplantation and managing certain autoimmune disorders.

How to use AMIGRAF 1.0 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with AMIGRAF 1.0 CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take AMIGRAF 1.0 CAPSULE 10'S exactly as prescribed by your doctor. Deviating from the prescribed dosage or schedule can impact the effectiveness of the medication.
  • To ensure proper absorption and effectiveness, do not open, break, crush, or chew the capsules. These capsules are designed to be swallowed whole with a full glass of water. This helps to deliver the medication to your system in the intended manner.
  • For optimal results, take AMIGRAF 1.0 CAPSULE 10'S on an empty stomach. This typically means taking the capsules at least one hour before a meal or waiting at least two to three hours after eating. This timing helps to minimize potential interactions with food that could affect the absorption of the medication. Following these instructions carefully will help you get the most benefit from AMIGRAF 1.0 CAPSULE 10'S.

Top Substitutes for AMIGRAF 1.0 CAPSULE 10'S

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TACROTEN 1MG CAP 1X10NEUTEN HEALTHCARE10186.56149.2520
ACOMUSKIN 1MG CAP 1X10ACCORD PHARMA102552396.27
XGRAF 1MG CAP 1X10APRAZER HEALTHCARE PVT LTD10379.07246.435
MYLIMUS 1MG CAP 1X10MYLAN PHARMACEUTICALS PRIVATE LIMITED10380.4228525.08
TACLORAN 1MG CAP 1X10WOCKHARDT LIMITED10346.13294.2115
TAPOID 1MG CAP 1X10SAMARTH LIFE SCIENCES PRIVATE LIMITED10378.84322.0215
SEEGRAF 1MG CAP 1X10MICRO LABS LIMITED10380.41323.3515
TACROL 1MG CAP 1X10MEDIART LIFE SCIENCES PVT LTD10362.81326.5310
IMUNOTAC 1MG CAP 1X10RPG LIFE SCIENCES LIMITED10408.2333218.67
TACRONIX 1MG CAP 1X10MEDGENIX PHARMA INDIA PRIVATE LIMITED10374.06336.6610
ODVENTA 1MG CAP 1X10ZYDUS LIFESCIENCES LIMITED10408.75347.4415
TACROMUS 1MG CAP 1X10ZYDUS LIFESCIENCES LIMITED10436.6349.2820
TACROGRAF 1MG CAP 1X10BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED10433.0335019.17
ELTACRO 1MG CAP 1X10ELDROGA LIFE SCIENCES PVT LTD10419.72356.7615
RINGRAF 1MG CAP 1X10RINDZ PHARMA PVT LTD10379.68360.75
TACSTEAD 1MG CAP 1X10STEADFAST MEDISHIELD PRIVATE LIMITED104003629.5
TACVA 1MG TAB 1X10IPCA LABORATORIES LIMITED10426.5362.5215
TACROCORD 1MG CAP 1X10CONCORD BIOTECH LTD10426.51362.5315
VINGRAF 1MG CAP 1X10EMCURE PHARMACEUTICALS LIMITED10426.51362.5315
TACSANT 1MG CAP 1X10NOVARTIS INDIA LIMITED10404.03363.6310
BIOMUS 1MG CAP 1X10ALNICHE LIFE SCIENCES PVT LTD10426.5136713.95
TACROREN 1MG CAP 1X10LA RENON HEALTHCARE PRIVATE LIMITED10432.18367.3515
KEYGRAF 1MG CAP 1X10ANTHEM BIOPHARMA10433.13368.1615
PANGRAF 1MG CAP 1X10MANKIND PHARMA LIMITED10433.91368.8215
TACROLYST 1MG CAP 1X10SEPTALYST LIFESCIENCES PVT LTD10410.63369.5610
TACSURE 1MG CAP 1X10MERYNOVA LIFE SCIENCES INDIA PRIVATE LIMITED10436.8371.2815
FUJIGRAF 1MG CAP 1X10HOSPIMAX HEALTHCARE PVT LTD10426.51383.8610
PROGRAF 1MG CAP 1X10ASTELLAS PHARMA INC10419.794131.62
TACROLIM 1MG CAP 1X10DR REDDY'S LABORATORIES LIMITED1030022624.67
RENGRAF 1MG CAP 1X10ABBOTT HEALTH CARE PRIVATE LIMITED10380.41323.3515
TAKFA 1MG CAP 1X10INTAS PHARMACEUTICALS LIMITED10433.9733123.73
ADVAGRAF 1MG CAP 1X10ASTELLAS PHARMA INC10937749.620

FAQs

What if I missed a dose of AMIGRAF 1.0 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with AMIGRAF 1.0 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take AMIGRAF 1.0 CAPSULE 10'S after a transplant?Arrow

The duration of AMIGRAF 1.0 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, AMIGRAF 1.0 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can AMIGRAF 1.0 CAPSULE 10'S increase the risk of infections?Arrow

Yes, AMIGRAF 1.0 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can AMIGRAF 1.0 CAPSULE 10'S affect kidney function?Arrow

AMIGRAF 1.0 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking AMIGRAF 1.0 CAPSULE 10'S?Arrow

AMIGRAF 1.0 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

Are there any known interactions of AMIGRAF 1.0 CAPSULE 10'S with other drugs?Arrow

Consult your doctor or pharmacist for information about interactions of AMIGRAF 1.0 CAPSULE 10'S with other drugs.

What advice should I follow while taking AMIGRAF 1.0 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using AMIGRAF 1.0 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is Tacrolimus and why is it used in AMIGRAF 1.0 CAPSULE 10'S?Arrow

Tacrolimus is an immunosuppressant used in AMIGRAF 1.0 CAPSULE 10'S to prevent organ rejection after transplantation.

How does AMIGRAF 1.0 CAPSULE 10'S help in conditions related to Nephrology?Arrow

AMIGRAF 1.0 CAPSULE 10'S is used in Nephrology to treat certain kidney disorders, especially after transplantation. It works by suppressing the immune system to prevent kidney rejection.

Is AMIGRAF 1.0 CAPSULE 10'S used to treat infectious diseases?Arrow

AMIGRAF 1.0 CAPSULE 10'S is primarily an immunosuppressant and is not typically used to treat infectious diseases directly. However, in some cases, it may be used to help control the immune response that can contribute to complications during infections.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Book Icon

Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Marketer / Manufacturer Details

BIOKINDLE LIFESCIENCES PRIVATE LIMITED

Country of Origin -

India

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AMIGRAF 1.0 CAPSULE 10'S

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₹346.64

15 % OFF

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