KEYGRAF 1 CAPSULE 10'S
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KEYGRAF 1 CAPSULE 10'S
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KEYGRAF 1 CAPSULE 10'S

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KEYGRAF 1 CAPSULE 10'S

By ANTHEM BIOPHARMA

MRP

433.13

₹368.16

15 % OFF

₹36.82 Only /

CAPSULE

10

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About KEYGRAF 1 CAPSULE 10'S

  • KEYGRAF 1 CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. This medication works by suppressing the activity of certain immune cells that would otherwise attack the transplanted organ, helping to ensure its survival within the recipient's body.
  • Do not take KEYGRAF 1 CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. It's crucial to monitor for these symptoms and report them promptly, as they could indicate serious complications.
  • Limit exposure to sunlight and UV light while consuming KEYGRAF 1 CAPSULE 10'S by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them. It is essential to discuss any planned vaccinations with your doctor to avoid potential adverse reactions due to your suppressed immune system. Regular check-ups and adherence to your doctor's instructions are vital for the safe and effective use of this medication.
  • This medication requires careful monitoring due to its potential side effects and interactions. Patients should maintain open communication with their healthcare providers, reporting any new symptoms or changes in their health status. Consistent adherence to the prescribed dosage and schedule is also crucial for optimal therapeutic outcomes and to minimize the risk of transplant rejection. Regular blood tests will be necessary to monitor tacrolimus levels and kidney function.

Uses of KEYGRAF 1 CAPSULE 10'S

  • Helps prevent organ transplant rejections by suppressing the immune system's response to the new organ, reducing the risk of complications.

Side Effects of KEYGRAF 1 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. KEYGRAF 1 CAPSULE 10'S can cause both common and serious side effects.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for KEYGRAF 1 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, KEYGRAF 1 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of KEYGRAF 1 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with KEYGRAF 1 CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take KEYGRAF 1 CAPSULE 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency of administration without consulting your healthcare provider.
  • To ensure optimal absorption and effectiveness, these capsules should be swallowed whole with a glass of water. Avoid opening, breaking, crushing, or chewing the capsules, as this could affect how the medication is released and absorbed by your body. For best results, take KEYGRAF 1 CAPSULE 10'S on an empty stomach, ideally at least 1 hour before a meal or 2 to 3 hours after eating.
  • Following these instructions carefully will help you get the most benefit from KEYGRAF 1 CAPSULE 10'S and minimize the risk of potential side effects. If you have any questions or concerns about how to take this medication, don't hesitate to ask your doctor or pharmacist for clarification.

How to store KEYGRAF 1 CAPSULE 10'S?Arrow

  • Keep KEYGRAF 1MG CAP 1X10 away from the reach of children and pets.
  • Store KEYGRAF 1MG CAP 1X10 at room temperature.

Benefits of KEYGRAF 1 CAPSULE 10'SArrow

  • KEYGRAF 1 CAPSULE 10'S is a medication that works by suppressing the immune system. It achieves this by targeting and inhibiting the activation and proliferation of T-lymphocytes, which are crucial components of the immune response. Furthermore, it hinders the T-helper-cell-dependent B-cell response, further dampening immune activity.
  • The mechanism of action involves binding to an intracellular protein known as FKBP-12. This binding results in the formation of a complex called tacrolimus-FKBP. This complex then inhibits calcineurin phosphatase, an enzyme essential for T-cell activation. By inhibiting calcineurin, KEYGRAF 1 CAPSULE 10'S effectively reduces the formation of T cells, leading to a suppression of the overall immune response. This makes it valuable in preventing organ rejection after transplantation and in managing certain autoimmune disorders.
  • By suppressing the immune system, KEYGRAF 1 CAPSULE 10'S helps to prevent the body from attacking a transplanted organ or its own tissues in autoimmune diseases. This targeted approach allows for the management of conditions where an overactive immune system is causing harm.

How to use KEYGRAF 1 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and length of treatment with KEYGRAF 1 CAPSULE 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to always take KEYGRAF 1 CAPSULE 10'S exactly as prescribed by your doctor. Adhering to their instructions is paramount for the medication to be effective and safe.
  • For optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. These capsules are designed to be swallowed whole with a full glass of water. This ensures that the medication is released properly in your system.
  • It is generally recommended to take KEYGRAF 1 CAPSULE 10'S on an empty stomach. This typically means taking it either at least 1 hour before a meal or waiting for 2 to 3 hours after eating. Following this guideline helps to maximize the absorption of the medication into your bloodstream. Consult your doctor or pharmacist if you have any questions about the best time to take KEYGRAF 1 CAPSULE 10'S with regard to meals.

FAQs

What if I missed a dose of KEYGRAF 1 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with KEYGRAF 1 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take KEYGRAF 1 CAPSULE 10'S after a transplant?Arrow

The duration of KEYGRAF 1 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, KEYGRAF 1 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can KEYGRAF 1 CAPSULE 10'S increase the risk of infections?Arrow

Yes, KEYGRAF 1 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can KEYGRAF 1 CAPSULE 10'S affect kidney function?Arrow

KEYGRAF 1 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy

Should I follow any dietary restrictions while taking KEYGRAF 1 CAPSULE 10'S?Arrow

KEYGRAF 1 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

What are the interactions of KEYGRAF 1 CAPSULE 10'S with other drugs?Arrow

KEYGRAF 1 CAPSULE 10'S can interact with other drugs.

What advice should I follow while taking KEYGRAF 1 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using KEYGRAF 1 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What molecule/combination is KEYGRAF 1 CAPSULE 10'S made of?Arrow

KEYGRAF 1 CAPSULE 10'S is made of TACROLIMUS molecule/combination.

For what ailments/diseases/conditions is KEYGRAF 1 CAPSULE 10'S prescribed?Arrow

KEYGRAF 1 CAPSULE 10'S is prescribed for ailments/diseases/conditions like Nephrology and Infectious Disease.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

Very good medkart and pharmacy and good discount for medicine

ASHOK MAKWANA

Reviewed on 14-02-2024

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(5/5)

Very good service and discount

Yatin Patel

Reviewed on 13-01-2024

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(5/5)

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

Reviewed on 05-12-2022

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(3/5)

Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

khozema kaukawala

Reviewed on 08-09-2023

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(5/5)

Good discount available on Generic medicines and supportive staff. Thank you.

ujjawal bhatt

Reviewed on 08-01-2024

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(5/5)


Marketer / Manufacturer Details

ANTHEM BIOPHARMA

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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