RENGRAF 1 CAPSULE 10'S
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RENGRAF 1 CAPSULE 10'S
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RENGRAF 1 CAPSULE 10'S

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RENGRAF 1 CAPSULE 10'S

By ABBOTT HEALTH CARE PRIVATE LIMITED

MRP

405.77

₹344.9

15 % OFF

₹34.49 Only /

CAPSULE

10

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Composition

Product DetailsArrow

About RENGRAF 1 CAPSULE 10'S

  • RENGRAF 1 CAPSULE 10'S contains the active substance Tacrolimus. It is classified as an immunosuppressant, specifically a calcineurin inhibitor. This medication is prescribed alongside other drugs to prevent the rejection of transplanted organs in individuals who have undergone liver, kidney, heart, or other organ transplants. Its primary function is to modulate your body’s immune response, allowing it to accept the transplanted organ and preventing it from being attacked by the body's natural defenses.
  • Before taking RENGRAF 1 CAPSULE 10'S, it is crucial to inform your physician if you have any known allergies to tacrolimus or any of the other inactive ingredients present in the capsule. Additionally, disclose any history of allergies to any group of antibiotics. It is also important to inform your doctor if you currently have or have had any liver or heart conditions prior to commencing treatment with this medication. Promptly notify your physician if you experience any of the following symptoms after taking this medicine: fever, unexplained bruising under the skin (which may manifest as red dots), persistent and unexplained tiredness, confusion or disorientation, yellowing of the skin or eyes (jaundice), reduced urine output, vision disturbances including vision loss, and seizures.
  • While taking RENGRAF 1 CAPSULE 10'S, it is essential to minimize your exposure to direct sunlight and ultraviolet (UV) light by wearing appropriate protective clothing and consistently using a sunscreen with a high sun protection factor (SPF). This precaution is necessary due to the potential risk of developing malignant skin changes associated with immunosuppressive therapy. This medicine may also induce diarrhea; therefore, inform your physician if you experience diarrhea lasting for more than a day. If you require any vaccinations while on this medication, consult your doctor beforehand to ensure they are safe and appropriate for you.
  • RENGRAF 1 CAPSULE 10'S works by suppressing the activity of certain immune cells, preventing them from attacking the transplanted organ. Regular blood tests are necessary to monitor the levels of tacrolimus in your blood and adjust the dosage accordingly. It is important to adhere strictly to your doctor's instructions regarding dosage and timing of administration to ensure the effectiveness of the medication and minimize the risk of side effects. Avoid grapefruit and grapefruit juice as it can affect the concentration of tacrolimus in the blood.

Uses of RENGRAF 1 CAPSULE 10'S

  • Prevent organ transplant rejections. RENGRAF 1 CAPSULE 10'S is used to lower the chance of the body rejecting a transplanted organ.

Side Effects of RENGRAF 1 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for RENGRAF 1 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, RENGRAF 1 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of RENGRAF 1 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with RENGRAF 1 CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take RENGRAF 1 CAPSULE 10'S exactly as prescribed by your doctor. Deviating from the prescribed dosage or schedule can affect the medication's effectiveness and potentially lead to adverse effects.
  • For optimal absorption and effectiveness, take RENGRAF 1 CAPSULE 10'S on an empty stomach. This typically means taking it at least one hour before a meal or waiting for two to three hours after you have eaten. This timing helps to ensure that the medication is not affected by food in your digestive system, allowing it to be absorbed properly into your bloodstream.
  • Swallow the RENGRAF 1 CAPSULE 10'S whole with a full glass of water. Do not attempt to open, break, crush, or chew the capsules. Altering the capsule in any way can affect how the medication is released and absorbed in your body, which could impact its effectiveness or safety. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist.
  • If you miss a dose of RENGRAF 1 CAPSULE 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's important to store RENGRAF 1 CAPSULE 10'S properly, according to the instructions provided on the packaging or by your pharmacist. Keep it out of reach of children and pets, and protect it from excessive heat, moisture, and direct sunlight.

How to store RENGRAF 1 CAPSULE 10'S?Arrow

  • Keep RENGRAF 1MG CAP 1X10 away from the reach of children and pets.
  • Store RENGRAF 1MG CAP 1X10 at room temperature.

Benefits of RENGRAF 1 CAPSULE 10'SArrow

  • RENGRAF 1 CAPSULE 10'S is an immunosuppressant medication that works by modulating the body's immune system to prevent organ rejection after transplants. It achieves this by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes, which are key cells involved in the immune response. Furthermore, it also suppresses the T-helper-cell-dependent B-cell response, further dampening the immune system's activity.
  • The drug's mechanism of action involves binding to an intracellular protein called FKBP-12, forming a complex known as tacrolimus-FKBP. This complex then inhibits the activity of calcineurin phosphatase, a crucial enzyme in the T-cell activation pathway. By inhibiting calcineurin, RENGRAF 1 CAPSULE 10'S effectively disrupts the signaling cascade required for T-cell maturation and function.
  • Ultimately, this targeted inhibition of T-cell activation and proliferation leads to a suppression of the immune response, reducing the likelihood of the body rejecting a transplanted organ. By selectively modulating the immune system, RENGRAF 1 CAPSULE 10'S helps to maintain the health and viability of the transplanted organ, improving the patient's overall outcome and quality of life. It allows the body to accept the new organ without attacking it.

How to use RENGRAF 1 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with RENGRAF 1 CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • Always take RENGRAF 1 CAPSULE 10'S exactly as prescribed. Avoid altering the dosage or frequency of administration without consulting your healthcare provider. Doing so may affect the efficacy of the treatment or increase the risk of side effects.
  • For optimal absorption and effectiveness, RENGRAF 1 CAPSULE 10'S should be swallowed whole with a full glass of water. Do not attempt to open, break, crush, or chew the capsules, as this could alter the way the medication is released and absorbed into your system.
  • It is generally recommended to take RENGRAF 1 CAPSULE 10'S on an empty stomach, which means either at least one hour before a meal or two to three hours after eating. This helps to ensure that the medication is absorbed properly and works effectively. If you have any concerns about how to take this medication with regards to food, please consult your doctor or pharmacist.

FAQs

What if I missed a dose of RENGRAF 1 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with RENGRAF 1 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take RENGRAF 1 CAPSULE 10'S after a transplant?Arrow

The duration of RENGRAF 1 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, RENGRAF 1 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can RENGRAF 1 CAPSULE 10'S increase the risk of infections?Arrow

Yes, RENGRAF 1 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can RENGRAF 1 CAPSULE 10'S affect kidney function?Arrow

RENGRAF 1 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking RENGRAF 1 CAPSULE 10'S?Arrow

RENGRAF 1 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important. 

What are the drug interactions of RENGRAF 1 CAPSULE 10'S with other drugs?Arrow

The interaction of RENGRAF 1 CAPSULE 10'S with other drugs is NULL.

What is the advice for using RENGRAF 1 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using RENGRAF 1 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly. 

Which molecule/combination is used for making RENGRAF 1 CAPSULE 10'S?Arrow

TACROLIMUS is molecule/combination used for making RENGRAF 1 CAPSULE 10'S.

For which ailments/diseases/conditions is RENGRAF 1 CAPSULE 10'S prescribed?Arrow

RENGRAF 1 CAPSULE 10'S is prescribed for ailments/diseases/conditions like Nephrology and Infectious Disease.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

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Dhaval Talaviya

Reviewed on 23-05-2023

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(5/5)

Best and cheapest medicine.

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Reviewed on 23-11-2022

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(5/5)

Good service in all medicines availability and specially in generic medicines. Very cheapest price to buy generic medicines at naroda area. saving money. Thank you medkart

Keyur Patel

Reviewed on 09-01-2024

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(5/5)

Good place to get your generic medicines.

shreyas potdar

Reviewed on 09-04-2024

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(5/5)

Super service

rensom christy

Reviewed on 06-01-2023

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(5/5)


Marketer / Manufacturer Details

ABBOTT HEALTH CARE PRIVATE LIMITED

Country of Origin -

India

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₹344.9

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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