TACROGRAF 1MG CAPSULE 10'S
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TACROGRAF 1MG CAPSULE 10'S

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TACROGRAF 1MG CAPSULE 10'S

By BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

MRP

454

₹350

22.91 % OFF

₹35 Only /

CAPSULE

10

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Composition

Product DetailsArrow

About TACROGRAF 1MG CAPSULE 10'S

  • TACROGRAF 1MG CAPSULE 10'S contains the active substance Tacrolimus, an immunosuppressant belonging to the calcineurin inhibitor class. This medication is prescribed alongside other drugs to prevent organ rejection in individuals who have undergone liver, kidney, heart, or other organ transplants. Its primary function is to regulate the body’s immune response, enabling the acceptance of the transplanted organ and preventing it from being attacked by the body's own defenses.
  • Before taking TACROGRAF 1MG CAPSULE 10'S, inform your healthcare provider if you have any known allergies to tacrolimus or any of the inactive ingredients present in the medicine. Also, disclose any allergies you might have to any group of antibiotics. It is crucial to inform your doctor about any pre-existing liver or heart conditions before commencing treatment with this medication. Promptly notify your physician if you experience symptoms such as fever, unexplained bruising under the skin (appearing as red dots), persistent fatigue, confusion, jaundice (yellowing of the skin or eyes), reduced urine output, vision disturbances, or seizures after starting this medicine.
  • While taking TACROGRAF 1MG CAPSULE 10'S, it is essential to minimize exposure to direct sunlight and ultraviolet (UV) light by wearing protective clothing and using a high SPF sunscreen. This precaution is due to the increased risk of malignant skin changes associated with immunosuppressive therapies. Be aware that this medicine may induce diarrhea; inform your doctor immediately if you experience diarrhea lasting more than a day. If you require any vaccinations, seek medical advice from your healthcare provider beforehand. Regular monitoring and adherence to your doctor's instructions are crucial for the safe and effective use of this medication. In addition, it is important to maintain adequate hydration and follow a balanced diet to support your overall health while on this medication. Report any new or worsening symptoms to your healthcare provider promptly.
  • Furthermore, TACROGRAF 1MG CAPSULE 10'S can interact with several other medications, potentially altering their effects or increasing the risk of side effects. Therefore, it is important to provide your doctor with a comprehensive list of all medications, supplements, and herbal products you are currently taking. This will allow your doctor to assess potential drug interactions and adjust your treatment plan accordingly. Be sure to attend all scheduled follow-up appointments with your healthcare provider to monitor your progress and address any concerns or questions you may have.

Uses of TACROGRAF 1MG CAPSULE 10'S

  • Prevent organ transplant rejections. TACROGRAF 1MG CAPSULE 10'S helps prevent organ rejection in patients who have undergone transplants.

How TACROGRAF 1MG CAPSULE 10'S Works

  • TACROGRAF 1MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
  • TACROGRAF 1MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, TACROGRAF 1MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, TACROGRAF 1MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of TACROGRAF 1MG CAPSULE 10'S in skin disorders is not fully understood.

Side Effects of TACROGRAF 1MG CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for TACROGRAF 1MG CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, TACROGRAF 1MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of TACROGRAF 1MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 1MG CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to strictly adhere to your doctor's prescribed dosage and instructions for optimal results and to minimize potential side effects.
  • Always take TACROGRAF 1MG CAPSULE 10'S exactly as prescribed by your healthcare provider. Do not attempt to open, break, crush, or chew the capsules, as this could affect the way the medication is absorbed and its effectiveness. Swallow the capsule whole with a glass of water to ensure it reaches your stomach intact.
  • For optimal absorption and effectiveness, it is generally recommended to take TACROGRAF 1MG CAPSULE 10'S on an empty stomach. This means taking it either at least 1 hour before a meal or 2 to 3 hours after eating. Following these guidelines can help ensure that the medication is properly absorbed into your bloodstream and works as intended.

How to store TACROGRAF 1MG CAPSULE 10'S?Arrow

  • Keep TACROGRAF 1MG CAP 1X10 away from the reach of children and pets.
  • Store TACROGRAF 1MG CAP 1X10 at room temperature.

Benefits of TACROGRAF 1MG CAPSULE 10'SArrow

  • TACROGRAF 1MG CAPSULE 10'S is an immunosuppressant medication that plays a crucial role in preventing organ rejection after transplantation. It works by selectively suppressing the immune system, reducing the risk of the body attacking the transplanted organ. The active ingredient, tacrolimus, achieves this by interfering with the activation and proliferation of T-lymphocytes, key players in the immune response.
  • Specifically, TACROGRAF 1MG CAPSULE 10'S inhibits T-lymphocyte activation and proliferation, as well as the T-helper-cell-dependent B-cell response. Its mechanism involves binding to an intracellular protein known as FKBP-12, forming a complex referred to as tacrolimus-FKBP. This complex then inhibits calcineurin phosphatase, an enzyme essential for T-cell activation.
  • By blocking calcineurin phosphatase, TACROGRAF 1MG CAPSULE 10'S effectively prevents the formation of T cells, thereby suppressing the immune response. This targeted approach helps to protect the transplanted organ from immune-mediated damage, increasing the likelihood of successful transplantation outcomes and improving the patient's long-term health.

How to use TACROGRAF 1MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with TACROGRAF 1MG CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • Always take TACROGRAF 1MG CAPSULE 10'S exactly as prescribed. Do not attempt to open, break, crush, or chew the capsules, as this could affect how the medication is absorbed and utilized by your body. Instead, swallow the capsule whole with a full glass of water.
  • For optimal absorption and effectiveness, take these capsules on an empty stomach. Specifically, ensure that you take them either at least 1 hour before a meal or 2 to 3 hours after eating. This timing helps to minimize any potential interactions between the medication and food, allowing for consistent and predictable results. Consistency in following these instructions is vital for achieving the best possible outcome from your treatment with TACROGRAF 1MG CAPSULE 10'S.

FAQs

What if I missed a dose of TACROGRAF 1MG CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with TACROGRAF 1MG CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take TACROGRAF 1MG CAPSULE 10'S after a transplant?Arrow

The duration of TACROGRAF 1MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, TACROGRAF 1MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can TACROGRAF 1MG CAPSULE 10'S increase the risk of infections?Arrow

Yes, TACROGRAF 1MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can TACROGRAF 1MG CAPSULE 10'S affect kidney function?Arrow

TACROGRAF 1MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking TACROGRAF 1MG CAPSULE 10'S?Arrow

TACROGRAF 1MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

What are the interactions of TACROGRAF 1MG CAPSULE 10'S with other drugs?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

What advice should I follow while using TACROGRAF 1MG CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using TACROGRAF 1MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is Tacrolimus?Arrow

Tacrolimus is a molecule/combination used for making TACROGRAF 1MG CAPSULE 10'S.

For which ailments/diseases/conditions is TACROGRAF 1MG CAPSULE 10'S prescribed?Arrow

TACROGRAF 1MG CAPSULE 10'S is prescribed for Nephrology and Infectious Diseases.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

Good experience with best medicine purchase at affordablee prices.

Aman Rohit M

Reviewed on 05-02-2024

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(5/5)

Good Medicines at affordable price. And good pharmacist who guide you with smile on their face.

Kaushal Parekh

Reviewed on 18-01-2024

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(5/5)

Best

amit sharma

Reviewed on 17-07-2023

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(5/5)

Best service always... Best staff ..thank u being over life part

Nisha Khan

Reviewed on 01-07-2023

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(5/5)

Good and cost effective medicines

Vishal Chaudhari

Reviewed on 15-02-2024

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(5/5)


Marketer / Manufacturer Details

BIOCON BIOPHARMACEUTICALS PRIVATE LIMITED

Country of Origin -

India

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TACROGRAF 1MG CAPSULE 10'S

MRP

454

₹350

22.91 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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