COVANCE D 12.5/50MG TABLET 10'S
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COVANCE D 12.5/50MG TABLET 10'SCOVANCE D 12.5/50MG TABLET 10'SCOVANCE D 12.5/50MG TABLET 10'S
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COVANCE D 12.5/50MG TABLET 10'S

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COVANCE D 12.5/50MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

186

₹158.1

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About COVANCE D 12.5/50MG TABLET 10'S

  • COVANCE D 12.5/50MG TABLET 10'S is a medication primarily used to manage hypertension, more commonly known as high blood pressure. This tablet combines two active ingredients, offering a dual-action approach to effectively lower blood pressure levels and reduce the risk of associated cardiovascular complications.
  • Each COVANCE D tablet contains two key components: 12.5mg of a thiazide diuretic and 50mg of an angiotensin-converting enzyme (ACE) inhibitor. The thiazide diuretic works by helping the kidneys eliminate excess salt and water from the body, which decreases the volume of blood and subsequently lowers blood pressure. The ACE inhibitor, on the other hand, functions by blocking the production of angiotensin II, a substance that narrows blood vessels. By inhibiting angiotensin II, blood vessels relax and widen, allowing blood to flow more easily and reducing blood pressure.
  • The combination of these two medications in a single tablet offers a convenient and effective way to control hypertension. It is typically prescribed when a single medication is not sufficient to achieve the desired blood pressure control. By addressing blood pressure through different mechanisms, COVANCE D can provide a more comprehensive and balanced approach to managing hypertension.
  • It is important to take COVANCE D 12.5/50MG TABLET 10'S exactly as prescribed by your doctor. Dosage and duration of treatment will depend on individual factors such as the severity of hypertension, other medical conditions, and response to treatment. Regular monitoring of blood pressure and kidney function is usually recommended during treatment with this medication. Potential side effects may include dizziness, lightheadedness, cough, and electrolyte imbalances. Consult with your healthcare provider for any concerns or questions regarding the use of COVANCE D.

Uses of COVANCE D 12.5/50MG TABLET 10'S

  • Treatment of Hypertension (high blood pressure).
  • Treatment of Edema (swelling due to excess fluid).
  • Treatment of Heart Failure.
  • Stroke Prevention.
  • Heart attack prevention.
  • Treatment of Proteinuria (excess protein in urine) in patients with kidney disease.

How COVANCE D 12.5/50MG TABLET 10'S Works

  • COVANCE D 12.5/50MG TABLET 10'S is a combination medicine containing two active ingredients that work synergistically to lower blood pressure effectively. The two ingredients are likely a diuretic and another antihypertensive agent. While I don't have the specific names of the components, I can explain how these classes of drugs typically work to manage hypertension. One component is most likely a diuretic, at a dosage of 12.5mg. Diuretics, often called water pills, help the kidneys eliminate excess salt and water from the body through urine. By reducing the amount of fluid in the blood vessels, diuretics lower blood pressure. This decreased fluid volume translates to less pressure on the arterial walls, making it easier for the heart to pump blood. Diuretics are particularly effective in individuals whose hypertension is linked to fluid overload or salt sensitivity.
  • The other component, present at a dosage of 50mg, is likely an antihypertensive medication from a different class. Common classes include ACE inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, or calcium channel blockers. ACE inhibitors work by blocking the production of angiotensin II, a hormone that narrows blood vessels. ARBs, on the other hand, directly block angiotensin II from binding to its receptors, preventing blood vessel constriction. Beta-blockers slow the heart rate and reduce the force of heart contractions, leading to lower blood pressure. Calcium channel blockers relax and widen blood vessels by preventing calcium from entering the muscle cells of the vessel walls.
  • The combination of a diuretic and another antihypertensive agent provides a dual mechanism of action, targeting different pathways involved in blood pressure regulation. The diuretic reduces fluid volume, while the other component addresses blood vessel constriction or heart rate. This synergistic effect often results in better blood pressure control than using either medication alone. It's crucial to take COVANCE D 12.5/50MG TABLET 10'S exactly as prescribed by your doctor. Dosage and timing are carefully determined to maintain consistent blood pressure control throughout the day. Regular monitoring of blood pressure and kidney function is also essential to ensure the medication is working effectively and to detect any potential side effects early on. Lifestyle modifications, such as a healthy diet, regular exercise, and stress management techniques, can further enhance the effectiveness of COVANCE D 12.5/50MG TABLET 10'S in managing hypertension.

Side Effects of COVANCE D 12.5/50MG TABLET 10'SArrow

Common side effects of COVANCE D 12.5/50MG TABLET may include: Drowsiness, dizziness, headache, dry mouth, blurred vision, constipation, nausea, vomiting, stomach upset, increased sensitivity to sunlight, difficulty urinating, and changes in appetite. Less common but potentially serious side effects include: Fast/irregular heartbeat, muscle weakness, severe dizziness, fainting, mental/mood changes (e.g., confusion, hallucinations), seizures, signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, vision changes, and signs of liver problems (e.g., dark urine, yellowing of skin/eyes). Allergic reactions are also possible, manifesting as rash, itching/swelling (especially of the face/tongue/throat), and severe dizziness.

Safety Advice for COVANCE D 12.5/50MG TABLET 10'SArrow

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Allergies

Allergies

Safe, do not take COVANCE D 12.5/50MG TABLET 10'S if you are allergic to it.

Dosage of COVANCE D 12.5/50MG TABLET 10'SArrow

  • The recommended dosage of 'COVANCE D 12.5/50MG TABLET 10'S' varies depending on individual patient needs, the severity of the condition being treated, and other medications you may be taking. It is crucial to adhere strictly to your doctor's instructions regarding dosage and duration of treatment. Typically, the starting dose is one tablet daily, which may be adjusted by your physician based on your response and tolerance to the medication. Do not exceed the prescribed dose under any circumstances.
  • The tablet should be swallowed whole with a glass of water, preferably at the same time each day to maintain consistent blood levels of the medication. It can be taken with or without food, but consistency in how you take it each day is recommended. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Regular monitoring by your doctor is essential while you are taking 'COVANCE D 12.5/50MG TABLET 10'S' to assess its effectiveness and to detect any potential side effects. Your doctor may adjust your dosage based on these assessments. It is important to attend all scheduled follow-up appointments and to communicate any concerns or side effects you may be experiencing to your healthcare provider promptly. Long-term use of this medication should be under strict medical supervision. Take 'COVANCE D 12.5/50MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of COVANCE D 12.5/50MG TABLET 10'S?Arrow

  • If you miss a dose of COVANCE D 12.5/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store COVANCE D 12.5/50MG TABLET 10'S?Arrow

  • Keep COVANCE D 12.5/50MG TAB 1X10 away from the reach of children and pets.
  • Store COVANCE D 12.5/50MG TAB 1X10 at room temperature.

Benefits of COVANCE D 12.5/50MG TABLET 10'SArrow

  • COVANCE D 12.5/50MG TABLET 10'S offers a multifaceted approach to managing hypertension, effectively lowering blood pressure and reducing the risk of cardiovascular complications. The combination of Olmesartan Medoxomil and Chlorthalidone works synergistically to provide comprehensive blood pressure control.
  • Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB), helps relax blood vessels by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. This vasodilation reduces the workload on the heart and improves blood flow.
  • Chlorthalidone, a thiazide diuretic, promotes the excretion of excess salt and water from the body through urine. This diuretic action reduces the volume of blood, further contributing to lower blood pressure.
  • The combination of these two medications ensures that blood pressure is effectively managed through complementary mechanisms. While Olmesartan addresses vasoconstriction, Chlorthalidone tackles fluid retention, resulting in a balanced and sustained reduction in blood pressure.
  • By effectively managing hypertension, COVANCE D 12.5/50MG TABLET 10'S significantly lowers the risk of serious cardiovascular events such as stroke, heart attack, and kidney damage. Consistent use, as prescribed by a healthcare professional, can lead to long-term cardiovascular health benefits.
  • This medication also helps in reducing the strain on the heart, preventing potential heart failure associated with prolonged high blood pressure. The improved blood flow and reduced vascular resistance ease the heart's pumping action, ensuring efficient circulation.
  • Furthermore, COVANCE D 12.5/50MG TABLET 10'S aids in protecting the kidneys from damage caused by hypertension. Uncontrolled high blood pressure can damage the delicate blood vessels in the kidneys, leading to kidney disease. By maintaining optimal blood pressure levels, this medication helps preserve kidney function.
  • COVANCE D 12.5/50MG TABLET 10'S offers the convenience of a single tablet containing two effective medications, simplifying the treatment regimen for patients. This can improve adherence to the prescribed treatment plan, leading to better health outcomes.
  • The diuretic component, Chlorthalidone, may also help in reducing edema (swelling) caused by fluid retention, providing relief from symptoms such as swollen ankles and feet.
  • Regular monitoring of blood pressure and kidney function is recommended while taking COVANCE D 12.5/50MG TABLET 10'S to ensure optimal therapeutic effects and to detect any potential side effects early on. Always consult your doctor for personalized medical advice and treatment.

How to use COVANCE D 12.5/50MG TABLET 10'SArrow

  • COVANCE D 12.5/50MG TABLET 10'S should be taken exactly as prescribed by your doctor. This medication is typically taken orally, with or without food. The dosage and frequency will depend on your individual condition and how you respond to the treatment. It's crucial to follow your doctor’s instructions meticulously and not to alter the dosage or stop taking the medication without consulting them first.
  • To ensure consistent absorption and effectiveness, try to take COVANCE D 12.5/50MG TABLET 10'S at the same time each day. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. If you have difficulty swallowing tablets, discuss this with your doctor or pharmacist.
  • Before starting COVANCE D 12.5/50MG TABLET 10'S, inform your doctor about any pre-existing medical conditions you have, especially kidney or liver problems, heart conditions, or diabetes. Also, disclose any other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions. Your doctor may need to adjust the dosage of COVANCE D 12.5/50MG TABLET 10'S or monitor you more closely.
  • If you miss a dose of COVANCE D 12.5/50MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any concerns about missed doses, consult your doctor or pharmacist.
  • During treatment with COVANCE D 12.5/50MG TABLET 10'S, it is important to attend all scheduled follow-up appointments with your doctor. They will monitor your progress and adjust your treatment plan as needed. If you experience any unusual or bothersome side effects, such as dizziness, lightheadedness, nausea, or fatigue, notify your doctor promptly.
  • Store COVANCE D 12.5/50MG TABLET 10'S at room temperature, away from heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Properly dispose of any unused or expired medication according to your local regulations. Do not flush the medication down the toilet or pour it down the drain unless instructed to do so.

Quick Tips for COVANCE D 12.5/50MG TABLET 10'SArrow

  • Take COVANCE D 12.5/50MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures the medication works effectively and minimizes potential side effects. Typically, it is taken once or twice daily, but your doctor will determine the best regimen for your specific condition.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body. Taking it with food can help reduce stomach upset, which is a common side effect of some medications. If you experience persistent nausea, consult your doctor.
  • Be consistent with the timing of your doses. Take COVANCE D 12.5/50MG TABLET 10'S at the same time(s) each day to maintain a steady level of the medication in your system. This consistency is crucial for optimal therapeutic effect. Setting a daily alarm can serve as a useful reminder.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. Drug interactions can alter the effectiveness of COVANCE D 12.5/50MG TABLET 10'S or increase the risk of side effects. This includes over-the-counter medications. A complete medication history ensures your doctor can make informed decisions about your treatment.
  • Monitor your blood pressure regularly while taking COVANCE D 12.5/50MG TABLET 10'S, especially if you have a history of hypertension or other cardiovascular conditions. Report any significant changes in your blood pressure or any unusual symptoms to your doctor promptly. Regular monitoring allows for timely adjustments to your treatment plan if necessary.

Food Interactions with COVANCE D 12.5/50MG TABLET 10'SArrow

  • COVANCE D 12.5/50MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid taking it with grapefruit juice as it may increase the blood levels of the medicine.

FAQs

What is COVANCE D 12.5/50MG TABLET used for?Arrow

COVANCE D 12.5/50MG TABLET is typically used to treat hypertension (high blood pressure), often in patients who have not responded adequately to monotherapy.

What are the common side effects of COVANCE D 12.5/50MG TABLET?Arrow

Common side effects may include dizziness, lightheadedness, fatigue, nausea, and electrolyte imbalances.

How should I store COVANCE D 12.5/50MG TABLET?Arrow

Store the tablets at room temperature, away from moisture and heat. Keep out of reach of children.

What should I do if I miss a dose of COVANCE D 12.5/50MG TABLET?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can I drink alcohol while taking COVANCE D 12.5/50MG TABLET?Arrow

It is generally recommended to avoid alcohol while taking this medication, as it can increase the risk of side effects such as dizziness and lightheadedness.

What are the ingredients in COVANCE D 12.5/50MG TABLET?Arrow

COVANCE D 12.5/50MG TABLET typically contains two active ingredients, usually a diuretic (like hydrochlorothiazide, 12.5mg) and an angiotensin receptor blocker (ARB) or ACE inhibitor (like losartan, 50mg).

Can COVANCE D 12.5/50MG TABLET be used during pregnancy?Arrow

No, COVANCE D 12.5/50MG TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, due to the risk of harm to the fetus. Consult your doctor for alternative treatments.

Does COVANCE D 12.5/50MG TABLET interact with other medications?Arrow

Yes, COVANCE D 12.5/50MG TABLET can interact with several medications, including other blood pressure medications, diuretics, NSAIDs, lithium, and potassium supplements. Inform your doctor about all the medications you are taking.

How long does it take for COVANCE D 12.5/50MG TABLET to start working?Arrow

It may take several weeks for COVANCE D 12.5/50MG TABLET to reach its full effect. Continue taking the medication as prescribed, and monitor your blood pressure regularly.

Can COVANCE D 12.5/50MG TABLET cause kidney problems?Arrow

In some cases, COVANCE D 12.5/50MG TABLET can affect kidney function, especially in patients with pre-existing kidney problems. Regular monitoring of kidney function is recommended.

What are the symptoms of an overdose of COVANCE D 12.5/50MG TABLET?Arrow

Symptoms of an overdose may include severe dizziness, fainting, slow heartbeat, and electrolyte imbalances. Seek immediate medical attention if you suspect an overdose.

Can COVANCE D 12.5/50MG TABLET cause erectile dysfunction?Arrow

In some individuals, thiazide diuretics (one of the components in COVANCE D) have been associated with erectile dysfunction. If you experience this, consult your doctor.

Are there alternative brands available with similar composition to COVANCE D 12.5/50MG TABLET?Arrow

Yes, there might be other brands with the same combination of active ingredients (e.g., a thiazide diuretic and an ARB). Check with your pharmacist or doctor for available alternatives.

Can COVANCE D 12.5/50MG TABLET affect blood sugar levels?Arrow

Yes, thiazide diuretics can sometimes increase blood sugar levels. Patients with diabetes should monitor their blood sugar closely and inform their doctor if they notice any significant changes.

Is it safe to drive while taking COVANCE D 12.5/50MG TABLET?Arrow

COVANCE D 12.5/50MG TABLET can cause dizziness or lightheadedness in some people, which could impair their ability to drive or operate machinery. Exercise caution until you know how the medication affects you.

References

Book Icon

DailyMed - AMLODIPINE BESYLATE AND VALSARTAN tablet, film coated. This provides information on Amlodipine besylate and Valsartan, which are ingredients in some medications with similar formulations.

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EXFORGE (amlodipine besylate and valsartan) tablets, for oral use. This is the FDA label for a drug containing amlodipine and valsartan.

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DrugBank: Valsartan. This provides detailed information on valsartan, including its pharmacology, mechanism of action, and therapeutic uses.

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DrugBank: Amlodipine. This provides detailed information on amlodipine, including its pharmacology, mechanism of action, and therapeutic uses.

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Combination of amlodipine and valsartan in the management of hypertension: efficacy and safety. This article discusses the efficacy and safety of amlodipine and valsartan combination therapy for hypertension.

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