LOSTAT H TABLET 15'S

How LOSTAT H TABLET 15'S Works

• LOSTAT H TABLET 15'S is a combination medicine containing Losartan and Hydrochlorothiazide, working synergistically to manage hypertension (high blood pressure). Losartan, an angiotensin II receptor blocker (ARB), selectively blocks the binding of angiotensin II to the AT1 receptors found in many tissues, including vascular smooth muscle and the adrenal gland. Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels, increasing blood pressure. By blocking its action, Losartan allows blood vessels to relax and widen, reducing blood pressure. It also reduces the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, further contributing to blood pressure reduction. Losartan provides long-lasting blood pressure control with a once-daily dosage due to its high affinity for the AT1 receptor and slow dissociation.
• Hydrochlorothiazide (HCTZ) is a thiazide diuretic, often referred to as a 'water pill.' It works primarily in the kidneys to inhibit the reabsorption of sodium and chloride in the distal convoluted tubule. This action increases the excretion of sodium and water, leading to a decrease in blood volume and, consequently, blood pressure. HCTZ also affects electrolyte balance, increasing the excretion of potassium and magnesium, which is why monitoring electrolyte levels is important during treatment. The diuretic effect of HCTZ also reduces the workload on the heart, improving overall cardiovascular function. By reducing sodium levels, HCTZ also reduces fluid retention and swelling.
• The combination of Losartan and Hydrochlorothiazide in LOSTAT H TABLET 15'S provides a complementary approach to blood pressure management. Losartan counteracts the sodium and water retention caused by Hydrochlorothiazide, while Hydrochlorothiazide enhances the blood pressure-lowering effect of Losartan. This synergistic effect allows for effective blood pressure control, often at lower doses of each individual component, minimizing potential side effects. The combined action effectively reduces both systolic (the pressure when the heart beats) and diastolic (the pressure when the heart rests between beats) blood pressure. Regular monitoring by a healthcare professional is crucial to ensure optimal blood pressure control and to manage any potential electrolyte imbalances.

Common side effects of LOSTAT H Tablet may include dizziness, lightheadedness, fatigue, headache, persistent dry cough, nausea, vomiting, diarrhea, stomach pain, back pain, muscle cramps, weakness, increased blood uric acid, electrolyte imbalance (including low sodium and potassium), increased sensitivity to sunlight, and skin rash. Less common but potentially serious side effects include kidney problems, allergic reactions (swelling of the face, lips, tongue, or throat; difficulty breathing), and changes in heart rhythm. This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any unusual symptoms while taking LOSTAT H Tablet.

• If you miss a dose of LOSTAT H TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep LOSTAT H TAB 1X15 away from the reach of children and pets.
• Store LOSTAT H TAB 1X15 at room temperature.

• Take LOSTAT H TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this could affect its effectiveness and increase the risk of side effects. Adherence to the prescribed regimen is crucial for managing your blood pressure effectively.
• LOSTAT H TABLET 15'S can be taken with or without food, but it's best to take it at the same time each day to maintain consistent blood levels of the medication. Consistency in timing optimizes its therapeutic effect. This also helps you remember to take it.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting LOSTAT H TABLET 15'S. This medication can interact with other substances, potentially leading to adverse effects or reduced efficacy. Include over-the-counter drugs and any recreational drug use.
• While taking LOSTAT H TABLET 15'S, monitor your blood pressure regularly, especially during the initial weeks of treatment or after any dosage adjustments. Keeping a log of your blood pressure readings and sharing them with your doctor during appointments will help in optimizing your treatment plan. Your doctor may also recommend home monitoring.
• LOSTAT H TABLET 15'S is most effective when combined with lifestyle modifications, such as a healthy diet, regular exercise, and stress management. Adopting these habits can significantly improve your overall cardiovascular health and reduce your reliance on medication. Aim for a balanced diet low in sodium and saturated fats, engage in at least 30 minutes of moderate-intensity exercise most days of the week, and practice stress-reducing techniques like yoga or meditation.

• LOSTAT H TABLET 15'S can be taken with or without food. Food does not significantly affect the absorption of this medication. However, it's advisable to take the medicine at the same time each day to maintain consistent blood levels and maximize its effectiveness. Always follow your doctor's instructions regarding dosage and timing.