DAPALEX S 10/100MG TABLET 10'S
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DAPALEX S 10/100MG TABLET 10'S
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DAPALEX S 10/100MG TABLET 10'S

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DAPALEX S 10/100MG TABLET 10'S

By AJANTA PHARMA LIMITED

MRP

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201.56

₹171.33

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About DAPALEX S 10/100MG TABLET 10'S

  • DAPALEX S 10/100MG TABLET 10'S is a combination medication designed to manage blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: Dapagliflozin (10mg) and Sitagliptin (100mg). This dual-action approach helps to control blood glucose more effectively than either medication used alone.
  • Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, thereby lowering blood sugar levels. This mechanism is also associated with modest weight loss and blood pressure reduction in some patients.
  • Sitagliptin, on the other hand, is a DPP-4 inhibitor (dipeptidyl peptidase-4 inhibitor). It enhances the levels of incretin hormones in the body. Incretins help regulate blood sugar by increasing insulin release after a meal and decreasing the amount of glucose produced by the liver. Sitagliptin works in a glucose-dependent manner, meaning it primarily affects blood sugar when levels are elevated.
  • DAPALEX S 10/100MG is typically prescribed in conjunction with diet and exercise to improve glycemic control. It's crucial to take this medication as directed by your healthcare provider. Regular monitoring of blood sugar levels is necessary to ensure the medication is working effectively and to adjust the dosage if needed. Potential side effects should be discussed with your doctor before starting treatment.
  • This medication offers a convenient way to manage type 2 diabetes by addressing multiple pathways involved in blood sugar regulation. Always consult with your physician or qualified healthcare professional for personalized medical advice, diagnosis, and treatment.

Uses of DAPALEX S 10/100MG TABLET 10'S

  • Helps in the treatment of diabetes
  • Aids in controlling blood sugar levels
  • Helpful in reducing cardiovascular risk
  • Assists in slowing the progression of kidney disease
  • Useful in managing type 2 diabetes

How DAPALEX S 10/100MG TABLET 10'S Works

  • DAPALEX S 10/100MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: dapagliflozin and sitagliptin, each working through distinct mechanisms to improve glycemic control.
  • Dapagliflozin belongs to a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin works by selectively inhibiting SGLT2, preventing the kidneys from reabsorbing glucose. This results in excess glucose being excreted in the urine, thereby lowering blood glucose levels. By reducing glucose reabsorption, dapagliflozin also promotes a mild diuretic effect, which can help lower blood pressure and potentially contribute to weight loss.
  • Sitagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released from the gut in response to food intake. They stimulate insulin release from the pancreas and suppress glucagon secretion from the liver, both of which help lower blood glucose levels. Sitagliptin works by inhibiting DPP-4, which increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion and reduced glucagon secretion in a glucose-dependent manner, meaning its effects are more pronounced when blood glucose levels are high, reducing the risk of hypoglycemia.
  • In summary, DAPALEX S 10/100MG TABLET 10'S utilizes a dual mechanism of action. Dapagliflozin promotes glucose excretion through the kidneys, while sitagliptin enhances the effects of incretin hormones to improve insulin secretion and reduce glucagon secretion. This synergistic approach helps to effectively lower blood sugar levels in individuals with type 2 diabetes. It is important to use this medication in conjunction with diet and exercise as part of a comprehensive diabetes management plan and as directed by your healthcare provider.

Side Effects of DAPALEX S 10/100MG TABLET 10'SArrow

Possible side effects of DAPALEX S 10/100MG TABLET 10'S may include: * **Common:** Nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, headache, dizziness, drowsiness, weakness, dry mouth, increased sweating, blurred vision, difficulty sleeping. * **Uncommon:** Anxiety, nervousness, tremors, palpitations, changes in blood pressure, skin rash, itching, muscle pain, joint pain, frequent urination, urinary tract infection, erectile dysfunction, changes in weight, abnormal liver function tests. * **Rare:** Serotonin syndrome (symptoms may include confusion, agitation, muscle twitching, rapid heartbeat), seizures, suicidal thoughts, bleeding problems, severe allergic reactions (rash, itching, swelling, dizziness, difficulty breathing).

Safety Advice for DAPALEX S 10/100MG TABLET 10'SArrow

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Allergies

Allergies

Do not use DAPALEX S 10/100MG TABLET if you are allergic to it or any of its ingredients.

Dosage of DAPALEX S 10/100MG TABLET 10'SArrow

  • The recommended dosage of DAPALEX S 10/100MG TABLET 10'S varies depending on individual patient needs and should be determined by your healthcare provider. Typically, the starting dose is one tablet daily, usually taken in the morning. Your doctor may adjust the dosage based on your response to the medication and your overall health condition. It is crucial to adhere to the prescribed dosage and not to exceed it without consulting your doctor.
  • DAPALEX S 10/100MG TABLET 10'S is usually taken orally with a glass of water. It can be taken with or without food, but consistency in timing is recommended to maintain stable blood sugar levels and ensure optimal efficacy. If you experience any gastrointestinal discomfort, taking it with food may help alleviate these symptoms.
  • It is important to take DAPALEX S 10/100MG TABLET 10'S every day at the same time to help you remember to take it. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Regular monitoring of blood sugar levels is advised while taking this medication to assess its effectiveness and adjust the treatment plan if needed.
  • Take 'DAPALEX S 10/100MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DAPALEX S 10/100MG TABLET 10'S?Arrow

  • If you miss a dose of DAPALEX S 10/100MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store DAPALEX S 10/100MG TABLET 10'S?Arrow

  • Keep DAPALEX S 10/100MG TAB 1X10 away from the reach of children and pets.
  • Store DAPALEX S 10/100MG TAB 1X10 at room temperature.

Benefits of DAPALEX S 10/100MG TABLET 10'SArrow

  • DAPALEX S 10/100MG TABLET 10'S is a combination medicine primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus. It combines two active ingredients, dapagliflozin and sitagliptin, each working through different mechanisms to achieve better glycemic control.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking the reabsorption of glucose in the kidneys, causing excess glucose to be excreted through urine. This helps to lower blood sugar levels and can also lead to modest weight loss and blood pressure reduction.
  • Sitagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It enhances the levels of incretin hormones in the body. These hormones stimulate insulin release from the pancreas and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By increasing insulin and decreasing glucagon, sitagliptin helps to lower blood sugar levels, particularly after meals.
  • The combined action of dapagliflozin and sitagliptin provides comprehensive glycemic control by addressing multiple pathways involved in blood sugar regulation. This dual mechanism can lead to more effective management of type 2 diabetes compared to using either drug alone.
  • Beyond blood sugar control, DAPALEX S 10/100MG TABLET 10'S may offer additional benefits. Dapagliflozin has been shown to have cardiovascular benefits in some patients, reducing the risk of heart failure and cardiovascular death. While sitagliptin's cardiovascular effects are still being studied, the combination may provide a more holistic approach to managing diabetes-related complications.
  • Furthermore, DAPALEX S 10/100MG TABLET 10'S is convenient for patients as it combines two medications into a single tablet, simplifying their treatment regimen and potentially improving adherence. This can be particularly helpful for individuals who are already taking multiple medications.
  • It's important to note that DAPALEX S 10/100MG TABLET 10'S should be used in conjunction with a healthy diet and regular exercise for optimal results. It is not a substitute for lifestyle modifications, but rather a tool to help manage blood sugar levels more effectively when lifestyle changes alone are not sufficient.
  • The medication should be taken as prescribed by a healthcare professional. Dosage and timing may vary depending on individual needs and other medical conditions. Regular monitoring of blood sugar levels and kidney function is recommended while taking DAPALEX S 10/100MG TABLET 10'S.
  • Possible side effects of DAPALEX S 10/100MG TABLET 10'S may include urinary tract infections, yeast infections, and changes in urination. It is important to discuss any concerns or side effects with a doctor. In rare cases, more serious side effects such as ketoacidosis can occur, so it is crucial to be aware of the symptoms and seek medical attention if needed.
  • In summary, DAPALEX S 10/100MG TABLET 10'S offers a multifaceted approach to managing type 2 diabetes by combining the blood sugar-lowering effects of dapagliflozin and sitagliptin, potentially providing cardiovascular benefits, and simplifying treatment regimens. It is an effective tool when used in conjunction with lifestyle modifications and under the guidance of a healthcare professional.

How to use DAPALEX S 10/100MG TABLET 10'SArrow

  • DAPALEX S 10/100MG TABLET 10'S should be taken orally, exactly as prescribed by your doctor. It's typically recommended to take this medication once daily, preferably in the morning, with or without food. However, consistency is key; try to take it around the same time each day to help you remember.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released in your body. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist; they may be able to offer alternative formulations or strategies.
  • Before starting DAPALEX S 10/100MG TABLET 10'S, inform your doctor about any other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. This is crucial to avoid potential drug interactions. Also, disclose any pre-existing medical conditions you may have, especially kidney problems, liver disease, heart conditions, or a history of allergic reactions to similar medications.
  • It is important to adhere to your doctor's instructions regarding dosage and duration of treatment. Do not abruptly stop taking DAPALEX S 10/100MG TABLET 10'S without consulting your doctor, as this could lead to withdrawal symptoms or a worsening of your condition. If you experience any bothersome side effects, such as nausea, dizziness, or headache, inform your doctor promptly. They may be able to adjust your dosage or recommend strategies to manage these side effects.
  • During treatment with DAPALEX S 10/100MG TABLET 10'S, it's advisable to monitor your blood sugar levels regularly, especially if you have diabetes. Regular check-ups with your doctor are also important to assess your progress and ensure the medication is working effectively. Lifestyle modifications, such as maintaining a healthy diet and engaging in regular exercise, can further enhance the benefits of this medication.

Quick Tips for DAPALEX S 10/100MG TABLET 10'SArrow

  • Take DAPALEX S 10/100MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could affect your blood sugar levels and overall health.
  • DAPALEX S 10/100MG TABLET 10'S is most effective when taken consistently at the same time each day. This helps maintain a steady level of the medication in your body, optimizing its ability to control blood sugar.
  • Be aware of the symptoms of both high (hyperglycemia) and low (hypoglycemia) blood sugar. Knowing these symptoms will allow you to take prompt action if your blood sugar levels become dangerously high or low. Discuss with your doctor what actions you should take in each situation.
  • While taking DAPALEX S 10/100MG TABLET 10'S, monitor your blood sugar levels regularly as directed by your doctor. Regular monitoring is essential to assess how well the medication is working and to make any necessary adjustments to your treatment plan. Keep a record of your blood sugar readings to share with your doctor.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Certain substances can interact with DAPALEX S 10/100MG TABLET 10'S, potentially affecting its efficacy or increasing the risk of side effects. A complete list helps your doctor manage your treatment safely and effectively.
  • Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity while taking DAPALEX S 10/100MG TABLET 10'S. These lifestyle modifications can significantly improve blood sugar control and overall well-being. Consult with a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise.
  • Stay well-hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function and overall health, which is especially important when taking medications that can affect blood sugar levels.
  • Store DAPALEX S 10/100MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Proper storage helps maintain the medication's effectiveness. Keep it out of reach of children and pets.
  • If you experience any unusual or concerning side effects while taking DAPALEX S 10/100MG TABLET 10'S, contact your doctor immediately. Prompt medical attention can help manage potential side effects and prevent complications.
  • Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are crucial for monitoring your health and making necessary adjustments to your diabetes management plan.

Food Interactions with DAPALEX S 10/100MG TABLET 10'SArrow

  • DAPALEX S 10/100MG TABLET 10'S can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood sugar levels. If you experience stomach upset, taking it with food may help.
  • Avoid excessive alcohol consumption while taking DAPALEX S 10/100MG TABLET 10'S as it can increase the risk of low blood sugar (hypoglycemia).

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FAQs

What is the use of DAPALEX S 10/100MG TABLET 10'S?Arrow

DAPALEX S 10/100MG TABLET 10'S is primarily used to treat type 2 diabetes mellitus. It helps in controlling blood sugar levels.

What are the active ingredients in DAPALEX S 10/100MG TABLET 10'S?Arrow

DAPALEX S 10/100MG TABLET 10'S contains two active ingredients: Dapagliflozin (10mg) and Sitagliptin (100mg).

What are the common side effects of DAPALEX S 10/100MG TABLET 10'S?Arrow

Common side effects of DAPALEX S 10/100MG TABLET 10'S may include nausea, vomiting, diarrhea, headache, and upper respiratory tract infection.

Is DAPALEX S 10/100MG TABLET 10'S safe for patients with kidney problems?Arrow

Patients with kidney problems should use DAPALEX S 10/100MG TABLET 10'S with caution and follow their doctor's advice, as it can affect kidney function.

How should I store DAPALEX S 10/100MG TABLET 10'S?Arrow

Store DAPALEX S 10/100MG TABLET 10'S at room temperature, away from direct sunlight and moisture.

Can DAPALEX S 10/100MG TABLET 10'S interact with other medications?Arrow

Yes, DAPALEX S 10/100MG TABLET 10'S can interact with certain other medications, such as insulin and some diuretics. Inform your doctor about all your medications.

Is DAPALEX S 10/100MG TABLET 10'S safe during pregnancy?Arrow

The safety of DAPALEX S 10/100MG TABLET 10'S during pregnancy has not been established. Pregnant women should consult a doctor before using it.

What is the recommended dosage of DAPALEX S 10/100MG TABLET 10'S?Arrow

The recommended dosage of DAPALEX S 10/100MG TABLET 10'S is usually one tablet once daily, but it's important to follow the dosage prescribed by your doctor.

What happens if I miss a dose of DAPALEX S 10/100MG TABLET 10'S?Arrow

If you miss a dose of DAPALEX S 10/100MG TABLET 10'S, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Does DAPALEX S 10/100MG TABLET 10'S cause weight gain?Arrow

DAPALEX S 10/100MG TABLET 10'S does not typically cause weight gain. In some cases, it may lead to slight weight loss.

Can DAPALEX S 10/100MG TABLET 10'S be taken with or without food?Arrow

DAPALEX S 10/100MG TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day.

Can DAPALEX S 10/100MG TABLET 10'S be used for type 1 diabetes?Arrow

No, DAPALEX S 10/100MG TABLET 10'S is only intended for the treatment of type 2 diabetes and not for type 1 diabetes.

Can DAPALEX S 10/100MG TABLET 10'S cause urinary tract infections (UTIs)?Arrow

Yes, DAPALEX S 10/100MG TABLET 10'S can increase the risk of urinary tract infections (UTIs). Contact your doctor if you experience symptoms of a UTI.

Can I drink alcohol while taking DAPALEX S 10/100MG TABLET 10'S?Arrow

It is not recommended to drink alcohol while taking DAPALEX S 10/100MG TABLET 10'S, as it can affect blood sugar levels and increase the risk of side effects.

What should I do if I overdose on DAPALEX S 10/100MG TABLET 10'S?Arrow

If you overdose on DAPALEX S 10/100MG TABLET 10'S, seek immediate medical attention or contact a poison control center.

References

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DrugBank: Dapagliflozin

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FDA: FARXIGA (dapagliflozin) tablets, for oral use. Full Prescribing Information

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European Medicines Agency: Forxiga (dapagliflozin). Summary of Product Characteristics

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DrugBank: Sitagliptin

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FDA: JANUVIA (sitagliptin) tablets, for oral use. Full Prescribing Information

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European Medicines Agency: Januvia (sitagliptin). Summary of Product Characteristics

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National Center for Biotechnology Information (NCBI): Efficacy and safety of dapagliflozin and sitagliptin as add-on therapy to metformin in patients with type 2 diabetes mellitus: A randomized, double-blind, active-controlled trial

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PubMed: Dapagliflozin and sitagliptin combination in patients with type 2 diabetes: Efficacy and safety profile

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Ratings & Review

All drugs available good service

Jayvadan Lalpara

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Reviewed on 23-01-2024

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(5/5)

Good service and they have too many varieties of products

shah dhruvi

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Reviewed on 13-03-2024

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(5/5)

Awesome

Pankaj Patel

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Reviewed on 13-06-2023

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(5/5)

Excellent service

Ali Akhtar

•

Reviewed on 26-07-2023

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(5/5)

Best experience Got Discount on medicine

Krushnapalsinh Rathod

•

Reviewed on 30-11-2023

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(5/5)


Marketer / Manufacturer Details

AJANTA PHARMA LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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