SITAGLO D TABLET 15'S

How SITAGLO D TABLET 15'S Works

• SITAGLO D tablet is a combination medicine containing two active ingredients: sitagliptin and dapagliflozin. These medications work through different but complementary mechanisms to lower blood sugar levels in individuals with type 2 diabetes.
• **Sitagliptin:** Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1), are released by the intestine in response to food intake. These hormones stimulate the pancreas to release insulin and inhibit the liver from producing excessive glucose. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This leads to increased insulin release when blood sugar is high (after meals) and decreased glucagon secretion, ultimately lowering blood sugar levels. Sitagliptin works in a glucose-dependent manner, meaning it primarily affects insulin release when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• **Dapagliflozin:** Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). SGLT2 is a protein in the kidneys that is responsible for reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, dapagliflozin reduces the reabsorption of glucose in the kidneys, causing more glucose to be excreted in the urine. This process lowers blood sugar levels. In addition to lowering blood sugar, dapagliflozin can also lead to weight loss and a modest reduction in blood pressure. It also has shown to have cardio-protective benefits.
• In summary, SITAGLO D works by using sitagliptin to enhance the body's own insulin response and reduce glucagon secretion, and dapagliflozin to increase glucose excretion through the kidneys. The combined effect of these two medications provides better blood sugar control than either medication alone. This dual mechanism addresses multiple aspects of type 2 diabetes, improving overall glycemic control and potentially offering additional benefits related to weight and cardiovascular health. It's crucial to use this medication as directed by your physician for safe and effective management of your diabetes.
• It's important to note that SITAGLO D is used in conjunction with diet and exercise to improve glycemic control. Regular monitoring of blood sugar levels is necessary, and individuals taking this medication should be aware of potential side effects and interactions with other medications. Always consult with a healthcare professional for personalized medical advice and guidance.

Common side effects of Sitaglo D Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and headache. Less common but potentially serious side effects include pancreatitis, severe allergic reactions (rash, itching, swelling), kidney problems, low blood sugar (hypoglycemia), and lactic acidosis. Other reported side effects are upper respiratory tract infection, stuffy or runny nose and sore throat.

• If you miss a dose of SITAGLO D TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAGLO D 10/100MG TAB 1X15 away from the reach of children and pets.
• Store SITAGLO D 10/100MG TAB 1X15 at room temperature.

• Take SITAGLO D TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this medication is designed to manage blood sugar levels effectively when taken correctly. Consistency is key for optimal results.
• SITAGLO D TABLET 15'S should be taken with food to minimize the risk of stomach upset. Food helps to improve the absorption of the medication and reduces potential gastrointestinal side effects. A consistent eating schedule will also aid in managing your blood sugar levels.
• Regularly monitor your blood sugar levels while taking SITAGLO D TABLET 15'S. Keeping a log of your readings and sharing them with your doctor during appointments allows for timely adjustments to your treatment plan. This proactive approach helps in maintaining better glycemic control.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting SITAGLO D TABLET 15'S. Drug interactions can affect the efficacy of this medication and may lead to unwanted side effects. A comprehensive medication review is crucial for your safety.
• Maintain a healthy lifestyle, including a balanced diet and regular exercise, while taking SITAGLO D TABLET 15'S. This medication works best when combined with lifestyle modifications. Physical activity and a nutritious diet can significantly improve your overall health and blood sugar control.

• SITAGLO D TABLET 15'S can be taken with or without food. However, it is important to take it at the same time each day to maintain consistent blood sugar levels. If you experience stomach upset, taking it with food may help.