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DEPAXIL CR PLUS 12.5MG TABLET 10'S

Name: DEPAXIL CR PLUS 12.5MG TABLET 10'S
Brand: ALKEM LABORATORIES LIMITED
Price: 194.44 INR
Availability: InStoreOnly

DEPAXIL CR PLUS 12.5MG TABLET 10'S

By ALKEM LABORATORIES LIMITED

MRP

₹

228.75

₹194.44

15 % OFF

₹19.44 Only /

Tablet

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Composition

CLONAZEPAM 0.5 MG+PAROXETINE 12.5 MG SUSTAINED RELEASE

Product Details

Content Reviewed By:

Dr. Rajesh Sharma

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About DEPAXIL CR PLUS 12.5MG TABLET 10'S

DEPAXIL CR PLUS 12.5MG TABLET 10'S is a carefully formulated medication designed to provide relief from symptoms associated with depression and anxiety disorders. It combines two active ingredients to offer a comprehensive approach to managing mental health. This medication is intended for individuals who require a sustained-release formulation for consistent symptom control throughout the day.
Each tablet contains a precise blend of active pharmaceutical ingredients. The 'CR' in the name stands for 'Controlled Release,' indicating that the medication is released gradually into the bloodstream. This controlled release mechanism helps to minimize fluctuations in drug concentration, reducing the likelihood of side effects and maintaining a stable therapeutic effect. The 'PLUS' signifies the combination of two active ingredients that work synergistically to alleviate symptoms. The specific ingredients and their respective dosages are carefully chosen to maximize efficacy while minimizing potential adverse reactions.
DEPAXIL CR PLUS is typically prescribed for conditions such as major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. It works by modulating the levels of certain neurotransmitters in the brain, such as serotonin and norepinephrine, which are believed to play a crucial role in mood regulation. By increasing the availability of these neurotransmitters, DEPAXIL CR PLUS helps to improve mood, reduce anxiety, and enhance overall well-being.
The recommended dosage and duration of treatment with DEPAXIL CR PLUS will vary depending on the individual's specific condition, severity of symptoms, and response to therapy. It is essential to follow the prescribing physician's instructions carefully. Patients should be aware of potential side effects, which may include nausea, dizziness, insomnia, and changes in appetite. It's important to consult with a healthcare professional if any concerning side effects occur. DEPAXIL CR PLUS should be stored in a cool, dry place, away from direct sunlight and out of reach of children.
This medication offers a convenient and effective way to manage depression and anxiety symptoms. Its controlled-release formulation promotes consistent symptom relief throughout the day, improving the patient's overall quality of life. Always use under medical supervision. It's important to disclose any other medications or supplements you are taking to your doctor before starting DEPAXIL CR PLUS, to avoid potential drug interactions. Regular follow-up appointments with your healthcare provider are necessary to monitor your progress and adjust your treatment plan as needed.

Uses of DEPAXIL CR PLUS 12.5MG TABLET 10'S

Treatment of Depression
Treatment of Anxiety Disorder
Treatment of Panic Disorder
Treatment of Social Anxiety Disorder (Social Phobia)
Treatment of Obsessive-Compulsive Disorder (OCD)
Treatment of Post-traumatic Stress Disorder (PTSD)
Treatment of Premenstrual Dysphoric Disorder (PMDD)

How DEPAXIL CR PLUS 12.5MG TABLET 10'S Works

DEPAXIL CR PLUS 12.5MG TABLET 10'S is a combination medicine designed to address mood disorders and anxiety. It contains two active ingredients that work synergistically to alleviate symptoms and improve overall mental well-being. Let's explore how each component contributes to the therapeutic effect:
**Paroxetine:** Paroxetine belongs to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). Serotonin is a neurotransmitter that plays a crucial role in regulating mood, emotions, and sleep. In individuals with depression or anxiety, serotonin levels in the brain may be imbalanced. Paroxetine works by selectively blocking the reuptake of serotonin in the synaptic cleft, the space between nerve cells. This action increases the concentration of serotonin available to bind to receptors on the receiving nerve cell, thereby enhancing serotonergic neurotransmission. By boosting serotonin levels, paroxetine helps to elevate mood, reduce anxiety, and improve sleep patterns.
**Clonazepam:** Clonazepam is a benzodiazepine, a class of medications known for their calming and anti-anxiety effects. It primarily acts on the central nervous system by enhancing the effects of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. GABA helps to reduce neuronal excitability, promoting relaxation and reducing anxiety. Clonazepam binds to specific receptors in the brain, amplifying GABA's inhibitory effects. This leads to a decrease in neuronal firing, which helps to calm the nervous system, alleviate anxiety symptoms such as excessive worry, restlessness, and irritability, and induce a sense of tranquility.
The combination of paroxetine and clonazepam in DEPAXIL CR PLUS 12.5MG TABLET 10'S offers a comprehensive approach to managing mood disorders and anxiety. Paroxetine addresses the underlying serotonin imbalance associated with depression and anxiety, while clonazepam provides rapid relief from acute anxiety symptoms. Together, these medications work synergistically to stabilize mood, reduce anxiety, improve sleep, and enhance overall quality of life. It is important to take DEPAXIL CR PLUS 12.5MG TABLET 10'S exactly as prescribed by your doctor and to follow their instructions carefully. Do not adjust the dosage or discontinue the medication without consulting your healthcare provider, as this may lead to withdrawal symptoms or a worsening of your condition. Regular follow-up appointments with your doctor are essential to monitor your progress and make any necessary adjustments to your treatment plan.
**In summary:** Paroxetine increases serotonin levels to improve mood, while Clonazepam enhances GABA to reduce anxiety. The combined effect provides a more balanced and effective treatment for mood disorders and anxiety.

Side Effects of DEPAXIL CR PLUS 12.5MG TABLET 10'S

Common side effects of DEPAXIL CR PLUS 12.5MG TABLET may include nausea, vomiting, diarrhea, constipation, dry mouth, changes in appetite or weight, dizziness, drowsiness, weakness, headache, nervousness, anxiety, agitation, insomnia, blurred vision, sweating, and sexual dysfunction. Less common but potentially serious side effects include serotonin syndrome (symptoms may include mental status changes, agitation, hallucinations, coma, fast heartbeat, tremors, muscle stiffness, nausea, vomiting, diarrhea), abnormal bleeding or bruising, seizures, angle-closure glaucoma, and allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing). This is not an exhaustive list; other side effects may occur. Consult your doctor or pharmacist for a complete list and medical advice.

Safety Advice for DEPAXIL CR PLUS 12.5MG TABLET 10'S

Allergies

Consult your Doctor

Dosage of DEPAXIL CR PLUS 12.5MG TABLET 10'S

The recommended dosage of 'DEPAXIL CR PLUS 12.5MG TABLET 10'S' varies significantly depending on the individual's condition, severity of symptoms, and response to treatment. It is crucial to adhere strictly to the dosage prescribed by your physician. Typically, treatment with 'DEPAXIL CR PLUS 12.5MG TABLET 10'S' is initiated at a low dose, which is then gradually increased over several weeks to minimize potential side effects and achieve the desired therapeutic effect. The usual starting dose might be one tablet daily, preferably taken in the morning with or without food. However, your doctor will determine the most appropriate starting dose based on your specific needs.
The maintenance dose, which is the dose needed to sustain improvement and prevent relapse, also varies from person to person. Your doctor will carefully monitor your progress and adjust the dosage accordingly. It is essential to attend all scheduled follow-up appointments and communicate any concerns or side effects you experience. Do not adjust the dosage on your own, even if you feel better or worse. Sudden changes in dosage can lead to adverse effects or a return of symptoms. The maximum recommended daily dose should never be exceeded.
If you miss a dose of 'DEPAXIL CR PLUS 12.5MG TABLET 10'S', take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure about what to do after missing a dose, consult your doctor or pharmacist for guidance. It is also important to note that 'DEPAXIL CR PLUS 12.5MG TABLET 10'S' is intended for long-term use. Do not stop taking it abruptly, as this can lead to withdrawal symptoms. Your doctor will gradually reduce the dose over time when it is appropriate to discontinue treatment. Take 'DEPAXIL CR PLUS 12.5MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

If you miss a dose of DEPAXIL CR PLUS 12.5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.

How to store DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Keep DEPAXIL CR PLUS 12.5MG TAB 1X10 away from the reach of children and pets.
Store DEPAXIL CR PLUS 12.5MG TAB 1X10 at room temperature.

Benefits of DEPAXIL CR PLUS 12.5MG TABLET 10'S

DEPAXIL CR PLUS 12.5MG TABLET 10'S is a combination medication primarily used to manage and treat various mental health conditions, offering a dual-action approach for comprehensive relief. One of its key benefits is its effectiveness in treating depression. The paroxetine component, a selective serotonin reuptake inhibitor (SSRI), helps to increase serotonin levels in the brain, which can alleviate symptoms of depression such as persistent sadness, loss of interest, and feelings of hopelessness. By stabilizing mood, it enables individuals to regain a sense of normalcy and improve their overall quality of life.
Beyond depression, DEPAXIL CR PLUS 12.5MG TABLET 10'S is also indicated for the treatment of anxiety disorders. The combination of paroxetine and another active ingredient works synergistically to reduce anxiety symptoms such as excessive worry, restlessness, and difficulty concentrating. This makes it particularly useful for individuals suffering from generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder. By modulating neurotransmitter activity, it helps to calm the mind and promote a sense of relaxation, reducing the frequency and intensity of anxiety attacks.
Another significant benefit of DEPAXIL CR PLUS 12.5MG TABLET 10'S is its ability to address obsessive-compulsive disorder (OCD). The paroxetine component helps to reduce the intrusive thoughts and compulsive behaviors that characterize OCD. By increasing serotonin levels, it helps to regulate thought patterns and reduce the urge to perform repetitive actions, thereby improving the individual's ability to function in daily life without being overwhelmed by obsessions and compulsions.
Furthermore, DEPAXIL CR PLUS 12.5MG TABLET 10'S can be beneficial in the treatment of post-traumatic stress disorder (PTSD). It helps to alleviate symptoms such as flashbacks, nightmares, and severe anxiety that are commonly associated with PTSD. By stabilizing mood and reducing anxiety, it enables individuals to process traumatic memories more effectively and regain a sense of control over their lives. This can lead to improved social functioning and a greater sense of well-being.
DEPAXIL CR PLUS 12.5MG TABLET 10'S offers a controlled-release formulation, which provides a steady release of the medication throughout the day. This helps to minimize fluctuations in drug levels and reduce the risk of side effects associated with rapid increases and decreases in medication concentration. The controlled-release mechanism also simplifies the dosing schedule, as it typically requires only once-daily administration, improving patient compliance and convenience. This can lead to better treatment outcomes and a more consistent therapeutic effect.
In addition to its direct therapeutic effects, DEPAXIL CR PLUS 12.5MG TABLET 10'S can also improve overall quality of life by addressing the underlying symptoms of mental health disorders. By reducing depression, anxiety, and obsessive-compulsive behaviors, it enables individuals to engage more fully in social activities, maintain healthy relationships, and pursue personal and professional goals. This can lead to increased self-esteem, a greater sense of purpose, and improved overall life satisfaction. The comprehensive approach of this medication makes it a valuable tool in managing complex mental health conditions and promoting long-term well-being.
The combination of different mechanisms of action in DEPAXIL CR PLUS 12.5MG TABLET 10'S can be particularly beneficial for individuals who have not responded adequately to single-agent therapy. By targeting multiple neurotransmitter systems, it increases the likelihood of achieving a therapeutic response and can provide more complete symptom relief. This can be especially important for individuals with treatment-resistant depression or anxiety, where traditional medications may not be fully effective. The synergistic effect of the combined ingredients offers a more robust and comprehensive approach to mental health treatment, improving the chances of a positive outcome.
DEPAXIL CR PLUS 12.5MG TABLET 10'S can also help to improve sleep quality, which is often disrupted in individuals with mental health disorders. By reducing anxiety and stabilizing mood, it can promote relaxation and facilitate more restful sleep. Improved sleep quality can, in turn, further enhance mood and cognitive function, creating a positive feedback loop that supports overall mental health. Adequate sleep is essential for optimal brain function and emotional regulation, and DEPAXIL CR PLUS 12.5MG TABLET 10'S can play a key role in restoring healthy sleep patterns.

How to use DEPAXIL CR PLUS 12.5MG TABLET 10'S

DEPAXIL CR PLUS 12.5MG TABLET 10'S should be taken exactly as prescribed by your doctor. It is usually taken once daily, in the morning or evening. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. This medication can be taken with or without food, but try to be consistent with your choice to minimize potential stomach upset.
The dosage of DEPAXIL CR PLUS 12.5MG TABLET 10'S will vary depending on your individual needs and response to treatment. Your doctor will likely start you on a low dose and gradually increase it until the desired effect is achieved. It is crucial to follow your doctor's instructions carefully and not to adjust the dosage on your own.
It is important to take DEPAXIL CR PLUS 12.5MG TABLET 10'S regularly to get the most benefit from it. Try to take it at the same time each day to help you remember. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Continue taking DEPAXIL CR PLUS 12.5MG TABLET 10'S even if you feel well. Do not stop taking this medication without talking to your doctor. Stopping suddenly can cause withdrawal symptoms, such as dizziness, nausea, anxiety, and flu-like symptoms. Your doctor will gradually reduce your dose over time to help prevent these symptoms.
If you experience any side effects, such as nausea, drowsiness, dizziness, or sexual dysfunction, talk to your doctor. They may be able to adjust your dose or recommend other ways to manage these side effects. Avoid alcohol while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S, as it can increase the risk of side effects. Store DEPAXIL CR PLUS 12.5MG TABLET 10'S at room temperature, away from heat, light, and moisture. Keep out of reach of children.

Quick Tips for DEPAXIL CR PLUS 12.5MG TABLET 10'S

**Take DEPAXIL CR PLUS 12.5MG TABLET 10'S as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dose or stop taking the medication without consulting your healthcare provider, as this could lead to withdrawal symptoms or a relapse of your condition.
**Be patient with the effects:** It may take several weeks to experience the full benefits of DEPAXIL CR PLUS 12.5MG TABLET 10'S. Continue taking the medication as prescribed, even if you don't notice immediate improvements. Discuss any concerns or lack of progress with your doctor.
**Manage potential side effects:** DEPAXIL CR PLUS 12.5MG TABLET 10'S can cause side effects such as nausea, dizziness, or changes in sleep patterns. Communicate any bothersome side effects to your doctor. They may be able to suggest ways to manage them or adjust your dosage.
**Avoid alcohol and other CNS depressants:** Alcohol and other substances that depress the central nervous system can interact with DEPAXIL CR PLUS 12.5MG TABLET 10'S, increasing the risk of side effects such as drowsiness and impaired coordination. Avoid these substances while taking this medication.
**Store properly and securely:** Keep DEPAXIL CR PLUS 12.5MG TABLET 10'S in a safe place, away from children and pets. Store at room temperature, away from moisture and direct sunlight. Do not use the medication if it has expired.
**Understand Potential Interactions:** Inform your doctor about all other medications, supplements, or herbal remedies you are taking. DEPAXIL CR PLUS 12.5MG TABLET 10'S can interact with other substances, which may affect how the medication works or increase the risk of side effects.
**Be aware of possible withdrawal symptoms:** When discontinuing DEPAXIL CR PLUS 12.5MG TABLET 10'S, do so gradually under the guidance of your doctor. Abruptly stopping the medication can cause withdrawal symptoms such as anxiety, insomnia, or flu-like symptoms. Your doctor can create a tapering schedule to minimize these effects.
**Monitor Mood Changes:** Pay close attention to any changes in your mood, thoughts, or behavior while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S. Contact your doctor immediately if you experience any worsening of depression, suicidal thoughts, panic attacks, or unusual changes in behavior.

Food Interactions with DEPAXIL CR PLUS 12.5MG TABLET 10'S

DEPAXIL CR PLUS 12.5MG TABLET 10'S can be taken with or without food, but it's generally recommended to take it at the same time each day to maintain consistent blood levels of the medication.
Avoid consuming large amounts of grapefruit or grapefruit juice while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S, as grapefruit can interact with the drug and increase the risk of side effects.
Be cautious about consuming alcohol while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S, as it may worsen drowsiness and other side effects. Consult your doctor or pharmacist for specific advice.
There are no specific dietary restrictions while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S unless advised by your doctor.

FAQs

What is DEPAXIL CR PLUS 12.5MG TABLET 10'S?

DEPAXIL CR PLUS 12.5MG TABLET 10'S is a medication used to treat depression and anxiety disorders. It contains a combination of paroxetine and clonazepam.

What is DEPAXIL CR PLUS 12.5MG TABLET 10'S used for?

DEPAXIL CR PLUS 12.5MG TABLET 10'S is used to treat conditions like depression, panic disorder, social anxiety disorder, and obsessive-compulsive disorder.

What are the common side effects of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Common side effects of DEPAXIL CR PLUS 12.5MG TABLET 10'S include nausea, dizziness, drowsiness, dry mouth, and constipation.

Is it safe to drink alcohol while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S?

It is not recommended to drink alcohol while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S, as it can increase side effects like drowsiness and dizziness.

Is DEPAXIL CR PLUS 12.5MG TABLET 10'S habit-forming?

DEPAXIL CR PLUS 12.5MG TABLET 10'S contains clonazepam, which can be habit-forming. Take it only as prescribed by your doctor.

How should I store DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Store DEPAXIL CR PLUS 12.5MG TABLET 10'S at room temperature, away from direct sunlight and moisture.

What happens if I miss a dose of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

If you miss a dose of DEPAXIL CR PLUS 12.5MG TABLET 10'S, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Is DEPAXIL CR PLUS 12.5MG TABLET 10'S safe for pregnant women?

DEPAXIL CR PLUS 12.5MG TABLET 10'S may not be safe during pregnancy. Consult your doctor before taking it.

Is DEPAXIL CR PLUS 12.5MG TABLET 10'S safe for breastfeeding women?

DEPAXIL CR PLUS 12.5MG TABLET 10'S may not be safe for breastfeeding women. Consult your doctor before taking it.

Is DEPAXIL CR PLUS 12.5MG TABLET 10'S safe for children?

DEPAXIL CR PLUS 12.5MG TABLET 10'S is generally not recommended for children. Consult your doctor before giving it.

What are the symptoms of an overdose of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Symptoms of an overdose of DEPAXIL CR PLUS 12.5MG TABLET 10'S may include excessive drowsiness, confusion, slow reflexes, and difficulty breathing.

Can DEPAXIL CR PLUS 12.5MG TABLET 10'S interact with other medications?

DEPAXIL CR PLUS 12.5MG TABLET 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking.

How long does it take for DEPAXIL CR PLUS 12.5MG TABLET 10'S to work?

It may take a few weeks for DEPAXIL CR PLUS 12.5MG TABLET 10'S to work fully.

Can I stop taking DEPAXIL CR PLUS 12.5MG TABLET 10'S suddenly?

Do not stop taking DEPAXIL CR PLUS 12.5MG TABLET 10'S suddenly, as it can cause withdrawal symptoms.

Can DEPAXIL CR PLUS 12.5MG TABLET 10'S cause weight gain?

Some people may experience weight gain while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S.

References

FDA Label for Paroxetine (Active Ingredient in Depaxil CR Plus): This document provides detailed information about paroxetine, including its chemical structure, mechanism of action, pharmacokinetics, clinical studies, and safety information.

DrugBank entry for Paroxetine: A comprehensive resource providing information on paroxetine's pharmacology, including its mechanism of action, absorption, metabolism, and excretion. It also includes chemical and structural data.

Paroxetine: A Review of its Pharmacology and Use in Psychiatric Disorders: Published in Clinical Medicine Insights. Therapeutics, this article reviews the pharmacokinetics, pharmacodynamics, efficacy, and safety profile of paroxetine in the treatment of various psychiatric disorders.

European Medicines Agency (EMA) - Paroxetine: This provides access to regulatory information and scientific assessments related to paroxetine, including potential risks and benefits.

Summary of Product Characteristics (SmPC) for Paroxetine (UK): This document provides detailed information intended for healthcare professionals about paroxetine, including its uses, dosage, contraindications, and side effects.

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

DEPAXIL CR PLUS 12.5MG TABLET 10'S

DEPAXIL CR PLUS 12.5MG TABLET 10'S

Product Details

About DEPAXIL CR PLUS 12.5MG TABLET 10'S

Uses of DEPAXIL CR PLUS 12.5MG TABLET 10'S

How DEPAXIL CR PLUS 12.5MG TABLET 10'S Works

Side Effects of DEPAXIL CR PLUS 12.5MG TABLET 10'S

Safety Advice for DEPAXIL CR PLUS 12.5MG TABLET 10'S

Dosage of DEPAXIL CR PLUS 12.5MG TABLET 10'S

What if I miss my dose of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

How to store DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Benefits of DEPAXIL CR PLUS 12.5MG TABLET 10'S

How to use DEPAXIL CR PLUS 12.5MG TABLET 10'S

Quick Tips for DEPAXIL CR PLUS 12.5MG TABLET 10'S

Food Interactions with DEPAXIL CR PLUS 12.5MG TABLET 10'S

FAQs

What is DEPAXIL CR PLUS 12.5MG TABLET 10'S?

What is DEPAXIL CR PLUS 12.5MG TABLET 10'S used for?

What are the common side effects of DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Is it safe to drink alcohol while taking DEPAXIL CR PLUS 12.5MG TABLET 10'S?

Is DEPAXIL CR PLUS 12.5MG TABLET 10'S habit-forming?

How should I store DEPAXIL CR PLUS 12.5MG TABLET 10'S?

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