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Content Reviewed By:
Dr. Manoj Shah
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Pexep Plus 12.5mg Capsule 10's may cause several side effects, although not everyone experiences them. Common side effects include nausea, dry mouth, constipation, decreased appetite, drowsiness, dizziness, blurred vision, increased sweating, and difficulty sleeping. Some individuals might also experience sexual dysfunction, such as decreased libido or erectile dysfunction. Less common but potentially serious side effects include serotonin syndrome (symptoms include agitation, hallucinations, rapid heart rate, fever, and muscle stiffness), abnormal bleeding or bruising, angle-closure glaucoma (eye pain, changes in vision, swelling in or around the eye), seizures, and suicidal thoughts or behaviors, especially at the beginning of treatment or when the dose is changed. Allergic reactions, though rare, can occur and may include rash, itching, swelling, severe dizziness, or trouble breathing. Other reported side effects are weight changes, restlessness, fatigue, tremor, and increased cholesterol levels. If any of these side effects become severe or persistent, or if you notice any other unusual symptoms, it is important to contact your doctor immediately.
Other medical conditions and drug interactions
Use under close supervisionPexep Plus 12.5 should be used with particular caution in patients with a history of seizures, bipolar disorder, glaucoma (especially narrow-angle), respiratory disorders such as chronic obstructive pulmonary disease or sleep apnea, or a history of substance misuse.
This medication is primarily used to treat depression, panic disorder, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).
Common side effects may include nausea, drowsiness, dizziness, dry mouth, constipation, and changes in sexual function.
No, it is not safe to suddenly stop taking PEXEP PLUS 12.5MG CAPSULE 10'S. It can cause withdrawal symptoms. Always consult your doctor to gradually reduce the dosage.
This medication works by increasing the levels of serotonin in the brain, which helps in regulating mood.
It is important to consult a doctor before using PEXEP PLUS 12.5MG CAPSULE 10'S during pregnancy, as it may affect the unborn child.
The dosage is determined by the doctor and depends on the individual's condition and response.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
Yes, PEXEP PLUS 12.5MG CAPSULE 10'S can interact with certain other medications. Therefore, inform your doctor about all your medications.
Store it at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.
You should avoid consuming alcohol while taking PEXEP PLUS 12.5MG CAPSULE 10'S, as it can increase the risk of side effects.
No, PEXEP PLUS 12.5MG CAPSULE 10'S is not a controlled substance, but it should only be taken with a doctor's prescription.
Weight gain can occur in some people taking PEXEP PLUS 12.5MG CAPSULE 10'S, but it varies from person to person.
Alternatives to PEXEP PLUS 12.5MG CAPSULE 10'S may include other antidepressant medications, but it's important to consult with a doctor.
If you experience any serious side effects, contact your doctor immediately or seek emergency medical help.
PEXEP PLUS 12.5MG CAPSULE 10'S can be taken with or without food, but it's best to take it at the same time each day.
Pexep Plus 12.5 is a combination of paroxetine (an SSRI antidepressant) and clonazepam (a benzodiazepine). It is generally prescribed for anxiety disorders, panic disorder, and depressive episodes associated with significant anxiety, as determined by a psychiatrist or physician. The paroxetine component helps improve mood and reduce long-term anxiety, while clonazepam provides short- to medium-term relief of acute anxiety and panic symptoms.
Paroxetine in Pexep Plus 12.5 increases serotonin levels in the brain by inhibiting its reuptake, which helps regulate mood, reduce anxiety, and alleviate depressive symptoms. Clonazepam enhances the effect of GABA, an inhibitory neurotransmitter, leading to reduced neuronal excitability and a calming, anxiolytic effect. Together, they address both the underlying mood disorder and the immediate anxiety or panic symptoms.
The clonazepam component usually starts to relieve anxiety and produce a calming effect within hours to a few days of starting treatment. However, the full antidepressant and long-term anxiolytic effects of paroxetine typically take 2 to 4 weeks or longer to become evident. Your doctor will usually review your response after a few weeks and may adjust treatment accordingly.
You should not stop Pexep Plus 12.5 abruptly without medical advice. Sudden discontinuation of clonazepam can cause withdrawal symptoms such as anxiety, insomnia, irritability, tremors, or, rarely, seizures. Stopping paroxetine suddenly can lead to discontinuation symptoms such as dizziness, flu-like feelings, sleep disturbances, and mood changes. Your doctor will usually recommend a gradual dose reduction if treatment needs to be stopped.
Common side effects may include drowsiness, dizziness, fatigue, impaired concentration, dry mouth, nausea, constipation or diarrhea, increased sweating, decreased libido, delayed ejaculation, and weight changes. Some people may also experience headache, tremor, or sleep disturbances. Many side effects are mild and may lessen as your body adjusts, but you should inform your doctor if they are persistent or troublesome.
The clonazepam component of Pexep Plus 12.5 is a benzodiazepine and can be habit-forming if used for prolonged periods or at higher than prescribed doses. This may lead to dependence and withdrawal symptoms when the medicine is reduced or stopped. Paroxetine itself is not considered addictive in the traditional sense, but it can cause discontinuation symptoms if stopped abruptly. To minimize risks, Pexep Plus 12.5 should be used at the lowest effective dose for the shortest duration necessary, under close medical supervision.
Alcohol should generally be avoided while taking Pexep Plus 12.5. Both clonazepam and alcohol depress the central nervous system, and their combined use can increase drowsiness, dizziness, impaired coordination, and risk of accidents. It may also worsen mood symptoms and interfere with the effectiveness of treatment. If you consume alcohol, discuss this with your doctor so that appropriate advice can be given.
Use of Pexep Plus 12.5 during pregnancy requires careful risk–benefit assessment by a specialist. Paroxetine has been associated in some studies with a small increased risk of certain birth defects and complications, especially when used in early pregnancy, while benzodiazepines like clonazepam may affect the fetus and can cause neonatal withdrawal or respiratory depression if used near delivery. Do not start or stop this medicine in pregnancy without consulting your obstetrician and psychiatrist.
Both paroxetine and clonazepam can pass into breast milk. Paroxetine is generally considered one of the SSRIs with lower levels in breast milk, but clonazepam may cause sedation, poor feeding, or breathing difficulties in the breastfed infant. The decision to use Pexep Plus 12.5 while breastfeeding should be individualized, weighing the benefits to the mother against potential risks to the infant. Close monitoring of the baby for excessive sleepiness, poor feeding, or unusual behavior is essential if the medicine is used.
If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects such as excessive drowsiness or dizziness. If you frequently forget doses, discuss strategies with your doctor or pharmacist.
Yes. Because Pexep Plus 12.5 contains clonazepam and can cause drowsiness, dizziness, slowed reaction time, and impaired concentration, it may affect your ability to drive, operate machinery, or perform tasks that require alertness. You should not drive or engage in hazardous activities until you know how the medicine affects you and your doctor confirms it is safe to do so.
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INTAS PHARMACEUTICALS LIMITED
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