ESOGRESS D CAPSULE 15'S

How ESOGRESS D CAPSULE 15'S Works

• ESOGRESS D CAPSULE 15'S is a combination medicine designed to treat gastroesophageal reflux disease (GERD) and peptic ulcers. It works through a dual mechanism involving esomeprazole and domperidone. Esomeprazole, a proton pump inhibitor (PPI), reduces the amount of acid produced in the stomach, while domperidone, a prokinetic agent, helps to speed up the emptying of the stomach and prevent acid from flowing back into the esophagus.
• Esomeprazole functions by selectively blocking the H+/K+-ATPase enzyme system (the ‘proton pump’) in gastric parietal cells. This enzyme system is the final step in acid production, so by inhibiting it, esomeprazole effectively decreases the secretion of gastric acid. This reduction in acidity helps to heal existing ulcers and erosions in the esophagus and stomach, relieves symptoms such as heartburn and acid regurgitation, and prevents further damage from occurring. Esomeprazole's targeted action ensures that acid production is controlled at its source, providing significant relief for individuals suffering from acid-related conditions.
• Domperidone works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) of the brain and in the gastrointestinal tract. By blocking these receptors in the CTZ, domperidone reduces nausea and vomiting. More importantly, domperidone enhances gastric motility by increasing the strength and coordination of contractions in the stomach. This promotes faster gastric emptying, reducing the amount of time food and acid remain in the stomach. Additionally, domperidone increases lower esophageal sphincter (LES) pressure, which helps to prevent acid reflux by strengthening the barrier between the stomach and the esophagus. The combined effect of increased gastric emptying and improved LES function minimizes the risk of acid flowing back into the esophagus, providing relief from GERD symptoms.
• The combination of esomeprazole and domperidone in ESOGRESS D CAPSULE 15'S provides a comprehensive approach to managing acid-related disorders. Esomeprazole reduces acid production, addressing the primary cause of irritation and damage, while domperidone enhances gastric motility and prevents acid reflux, tackling the secondary issues that exacerbate the condition. This synergistic action effectively alleviates symptoms such as heartburn, regurgitation, and nausea, while also promoting the healing of ulcers and erosions in the digestive tract. The controlled-release formulation of the capsule ensures a sustained therapeutic effect, providing long-lasting relief throughout the day and improving the overall quality of life for individuals suffering from GERD and related conditions.

Common side effects of Esogress D Capsule may include headache, dizziness, dry mouth, nausea, vomiting, stomach pain, diarrhea, constipation, flatulence (gas), and altered taste. Less common side effects may involve anxiety, sleep disturbances (insomnia), skin rash, itching, fatigue, blurred vision, and peripheral edema (swelling in the extremities). Rarely, Esogress D Capsule may cause more serious side effects such as severe allergic reactions (anaphylaxis), liver problems (indicated by jaundice, dark urine, or persistent fatigue), kidney problems, heart rhythm disturbances, muscle weakness or cramps, and changes in blood cell counts. Long-term use may increase the risk of bone fractures, particularly in the hip, wrist, or spine. Report any persistent or worsening side effects to your doctor immediately.

• If you miss a dose of Esogress D Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ESOGRESS D 40MG CAP 1X15 away from the reach of children and pets.
• Store ESOGRESS D 40MG CAP 1X15 at room temperature.

• Take Esogress D Capsule 15'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration.
• For optimal absorption, take Esogress D Capsule 15'S on an empty stomach, ideally 30-60 minutes before a meal, preferably in the morning. This helps the medicine work more effectively to reduce acid production.
• If you experience any persistent or worsening side effects like headache, diarrhea, or stomach pain, consult your doctor immediately. Do not self-treat or discontinue the medication without medical advice.
• Avoid consuming alcohol, caffeinated beverages, and spicy or fatty foods while taking Esogress D Capsule 15'S. These substances can irritate the stomach lining and reduce the effectiveness of the medication.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting Esogress D Capsule 15'S. This is to prevent potential drug interactions that could affect the medication's efficacy or increase the risk of side effects. Special caution should be taken if you are taking blood thinners.

• ESOGRESS D CAPSULE 15'S should be taken on an empty stomach, preferably 30-60 minutes before a meal. Food can significantly reduce the absorption of esomeprazole, one of the active ingredients, thereby decreasing its effectiveness. Taking it before food allows for optimal absorption and efficacy.
• Avoid consuming large meals or fatty foods immediately after taking ESOGRESS D CAPSULE 15'S, as these can further delay absorption and reduce the medication's impact. Consistent timing with respect to meals is crucial for managing acid reflux and related symptoms effectively.