INSUGEN 30/70 40IU VIAL 10 ML

How INSUGEN 30/70 40IU VIAL 10 ML Works

• INSUGEN 30/70 is a premixed insulin formulation containing 30% rapid-acting insulin and 70% intermediate-acting insulin. This combination allows for better blood sugar control throughout the day by addressing both prandial (meal-related) and basal (background) insulin needs. The rapid-acting component, which is a soluble insulin, starts working quickly after injection, helping to manage the rise in blood sugar levels that occur after eating. It typically begins to lower blood sugar within 30 minutes, with its peak effect occurring within 2 to 4 hours and lasting for up to 8 hours. This prompt action assists in controlling post-meal glucose excursions, preventing hyperglycemia immediately after food consumption.
• The intermediate-acting component, on the other hand, is a longer-lasting insulin that provides a more sustained release of insulin over a longer period. It usually starts working within 1 to 2 hours, peaks in 6 to 12 hours, and can last for up to 18 to 24 hours. This basal insulin coverage helps to keep blood sugar levels stable between meals and during the night, preventing hyperglycemia when the body is not actively digesting food. The specific proportions of rapid-acting and intermediate-acting insulin in INSUGEN 30/70 are designed to mimic the body's natural insulin release pattern, providing both immediate and prolonged glucose control.
• When INSUGEN 30/70 is injected subcutaneously (under the skin), the insulin is absorbed into the bloodstream, where it facilitates the transport of glucose from the blood into cells. Insulin binds to insulin receptors on the cell surface, triggering a cascade of intracellular events that ultimately lead to the translocation of glucose transporters (GLUT4) to the cell membrane. These glucose transporters then enable glucose to enter the cells, where it can be used for energy or stored as glycogen. By promoting glucose uptake into cells, INSUGEN 30/70 effectively lowers blood sugar levels.
• Furthermore, insulin also inhibits the liver from producing more glucose and reduces the breakdown of fat and protein, further contributing to lower blood glucose concentrations. The overall effect of INSUGEN 30/70 is to help people with diabetes maintain better control over their blood sugar levels, reducing the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Regular use of INSUGEN 30/70, in conjunction with a healthy diet and exercise, is crucial for effective diabetes management. It's important to note that individual responses to insulin can vary, so blood sugar levels should be monitored regularly, and the dosage adjusted as needed under the guidance of a healthcare professional.

Like all medicines, INSUGEN 30/70 can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): This is the most common side effect. Symptoms can include sweating, shakiness, dizziness, hunger, blurred vision, headache, rapid heartbeat, anxiety, irritability, confusion, difficulty concentrating, slurred speech, and in severe cases, loss of consciousness or seizures. Mild hypoglycemia can usually be treated by consuming sugary drinks or food. Severe hypoglycemia requires immediate medical attention. * Injection site reactions: Redness, swelling, itching, or pain at the injection site. * Lipodystrophy: Changes in fat tissue at the injection site (either thickening or pitting of the skin) can occur if injections are not rotated within an area. **Uncommon side effects (may affect up to 1 in 100 people):** * Allergic reactions: These can include rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing. Severe allergic reactions can be life-threatening. * Edema: Swelling of the ankles and feet may occur when starting insulin therapy or during dosage adjustments. **Rare side effects (may affect up to 1 in 1,000 people):** * Systemic allergic reaction: This is a very serious allergy with symptoms such as: skin rash over the whole body, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating. **Very rare side effects (may affect up to 1 in 10,000 people):** * Visual impairment: Changes in vision may occur at the beginning of insulin treatment but is usually temporary. **Other possible side effects:** * Weight gain: Insulin can cause weight gain. * Peripheral neuropathy: Insulin can sometimes cause nerve pain. This can show as numbness, burning, or tingling in your hands or feet.

• If you miss a dose of INSUGEN 30/70, it is important to check your blood sugar levels as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and take your next dose at the regular time. Do not double your dose to make up for the missed one. Contact your doctor or diabetes educator for guidance on managing missed doses to maintain optimal blood sugar control.

• Keep INSUGEN 30/70 40IU VIAL 10ML away from the reach of children and pets.
• Store INSUGEN 30/70 40IU VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** INSUGEN 30/70 is a premixed insulin, meaning it contains both rapid-acting and intermediate-acting insulin. The 30/70 ratio indicates that it consists of 30% rapid-acting insulin and 70% intermediate-acting insulin. This combination helps manage blood sugar levels after meals and between meals. Understanding this balance is crucial for effective diabetes management.
• **Timing is Key:** Administer INSUGEN 30/70 approximately 30 minutes before a meal. This allows the rapid-acting component to start working when you begin eating, preventing a post-meal blood sugar spike. Consistency in timing is important for predictable blood sugar control. Consult your doctor about the precise timing that suits your individual needs and meal schedule.
• **Proper Injection Technique:** Always inject INSUGEN 30/70 subcutaneously (under the skin). Rotate injection sites (abdomen, thigh, or upper arm) to prevent lipodystrophy (changes in fat tissue under the skin). Use a new needle for each injection to ensure sterility and reduce discomfort. Ask your healthcare provider for a demonstration of the correct injection technique.
• **Monitor Blood Glucose Regularly:** Regularly monitor your blood glucose levels as directed by your doctor. This helps you understand how INSUGEN 30/70 is affecting your blood sugar and allows you to make necessary adjustments to your diet, exercise, or insulin dosage. Keep a log of your blood glucose readings to share with your healthcare provider.
• **Be Aware of Hypoglycemia:** Hypoglycemia (low blood sugar) is a potential side effect of insulin. Recognize the symptoms, which include sweating, shakiness, dizziness, hunger, and confusion. Always carry a source of fast-acting sugar, such as glucose tablets or juice, to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia in case you are unable to do so yourself. Discuss with your doctor what to do if you experience frequent or severe hypoglycemic episodes.
• **Storage Matters:** Store unopened INSUGEN 30/70 vials in the refrigerator (2°C to 8°C). Once opened, the vial can be stored at room temperature (below 30°C) for up to 28 days. Avoid exposing the insulin to direct sunlight or extreme temperatures. Always check the appearance of the insulin before use; it should be clear and colorless. Do not use if it appears cloudy, thickened, or has particles.
• **Diet and Exercise Synchronization:** Coordinate your diet and exercise with your INSUGEN 30/70 injections. A balanced diet and regular physical activity are essential components of diabetes management. Talk to your doctor or a registered dietitian about creating a meal plan and exercise routine that works well with your insulin regimen. Consider how different foods and activities impact your blood sugar levels.
• **Travel Smart with Insulin:** When traveling, pack your INSUGEN 30/70 in your carry-on luggage to avoid temperature fluctuations in the cargo hold. Carry a prescription or a letter from your doctor explaining your need for insulin and syringes. If traveling across time zones, consult your doctor about adjusting your insulin dosage schedule.
• **Alcohol Consumption Caution:** If you consume alcohol, do so in moderation and with food. Alcohol can affect blood sugar levels and increase the risk of hypoglycemia, especially when taken with insulin. Monitor your blood glucose levels carefully if you drink alcohol.
• **Illness Management:** During illness, such as a cold or flu, your blood sugar levels may be more difficult to control. Continue to take your INSUGEN 30/70 as prescribed, but monitor your blood glucose levels more frequently. Consult your doctor if you are unable to eat or if your blood sugar levels are consistently high or low.

• INSUGEN 30/70 is typically administered before meals. It's crucial to maintain a consistent carbohydrate intake at each meal to avoid fluctuations in blood sugar levels. Discuss your dietary plan with your doctor or a certified diabetes educator to understand the appropriate amount and type of food to consume with each injection. Be mindful of foods high in sugar or simple carbohydrates, as these can cause rapid increases in blood sugar. Alcohol consumption can also affect blood sugar control, so it should be moderated and discussed with your doctor.