LUPISULIN M 30/70 40IU VIAL 10 ML

How LUPISULIN M 30/70 40IU VIAL 10 ML Works

• LUPISULIN M 30/70 40IU VIAL 10 ML is a premixed insulin formulation containing both rapid-acting and intermediate-acting human insulin. This combination helps to manage blood sugar levels effectively throughout the day. The '30/70' designation indicates the ratio of rapid-acting insulin (30%) to intermediate-acting insulin (70%). This specific ratio is designed to mimic the body's natural insulin release pattern, providing a bolus dose to cover mealtime glucose excursions and a basal dose to maintain consistent glucose levels between meals and overnight.
• The rapid-acting component of LUPISULIN M 30/70 is a soluble insulin that starts working within 30 minutes of injection. It helps to control the rise in blood sugar levels that occurs after eating. This rapid onset allows for greater flexibility in meal timing, as the insulin begins to work quickly to process the carbohydrates consumed.
• The intermediate-acting component is an isophane insulin suspension, which has a slower onset and a longer duration of action. It typically starts working within 1-2 hours and can last for up to 24 hours. This provides a background level of insulin to keep blood sugar levels stable between meals and during sleep. The protamine in the isophane insulin delays the absorption of the insulin, prolonging its effect.
• When injected subcutaneously, LUPISULIN M 30/70 is absorbed into the bloodstream. The rapid-acting insulin is quickly available to facilitate glucose uptake by cells, particularly in muscle and adipose tissue. Insulin binds to receptors on cell surfaces, triggering a cascade of intracellular events that lead to the translocation of glucose transporters (GLUT4) to the cell membrane. These transporters then enable glucose to enter the cells, reducing blood glucose levels.
• The intermediate-acting insulin is absorbed more slowly, providing a sustained release of insulin into the bloodstream. This helps to maintain a consistent level of insulin activity over a longer period, preventing hyperglycemia (high blood sugar) between meals. The combination of rapid and intermediate-acting insulin provides a comprehensive approach to blood sugar control.
• LUPISULIN M 30/70 is typically administered two or three times daily, about 30 minutes before meals. The dosage is individualized based on factors such as blood sugar levels, diet, activity level, and other medications. Regular monitoring of blood glucose levels is essential to adjust the dosage as needed to achieve optimal glycemic control. Proper injection technique is also crucial to ensure consistent absorption and minimize the risk of complications such as hypoglycemia (low blood sugar) or lipodystrophy (changes in fat tissue at the injection site).

Like all medicines, LUPISULIN M 30/70 40IU VIAL 10 ML can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * **Hypoglycemia (low blood sugar):** This is the most frequent side effect. Symptoms can include sweating, shaking, anxiety, blurred vision, rapid heartbeat, dizziness, headache, hunger, confusion, and irritability. Severe hypoglycemia can lead to unconsciousness and, in rare cases, be fatal. * **Injection Site Reactions:** Redness, swelling, itching, or pain at the injection site. * **Lipodystrophy:** Changes in fat tissue at the injection site (lipoatrophy - hollowing of the skin, or lipohypertrophy - thickening of the skin) can occur if injections are repeatedly given in the same area. **Uncommon Side Effects (may affect up to 1 in 100 people):** * **Allergic Reactions:** Skin rash, itching, hives. * **Edema:** Swelling of ankles and feet. **Rare Side Effects (may affect up to 1 in 1,000 people):** * **Severe Allergic Reaction (Anaphylaxis):** Symptoms can include difficulty breathing, wheezing, rapid heartbeat, sweating, and a drop in blood pressure. This is a medical emergency. **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * **Visual Disturbances:** Temporary visual impairment at the beginning of insulin therapy. * **Myalgia:** Muscle pain. **Other Possible Side Effects:** * Weight gain * Peripheral neuropathy (nerve damage causing pain, numbness, or tingling) * Sodium retention **Important Information:** * If you experience symptoms of low blood sugar, treat it immediately with a fast-acting source of sugar like glucose tablets or sugary drinks. * Rotate injection sites to help prevent lipodystrophy. * Seek immediate medical attention if you experience symptoms of a severe allergic reaction.

• If you miss a dose of Lupisulin M 30/70, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Contact your doctor if you are unsure about what to do.

• Keep LUPISULIN M 30/70 40IU VIAL 10ML away from the reach of children and pets.
• Store LUPISULIN M 30/70 40IU VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** LUPISULIN M 30/70 is a premixed insulin, containing 30% rapid-acting insulin and 70% intermediate-acting insulin. It's crucial to understand this combination to manage your blood sugar levels effectively. Knowing the onset, peak, and duration of each component will help you time your meals and activities appropriately. Consult your doctor or diabetes educator to fully understand how this specific mix works for *your* individual needs. Never adjust your dosage without professional guidance.
• **Proper Storage is Key:** Always store your unopened LUPISULIN M 30/70 vials in the refrigerator (2°C to 8°C or 36°F to 46°F). Avoid freezing. Once opened, the vial can be kept at room temperature (below 25°C or 77°F) for up to 28 days. Protect it from direct heat and light. Discard the vial if it has been open for longer than 28 days, even if there's insulin remaining. Record the date you opened the vial to help you keep track.
• **Injection Technique Matters:** Use a new, sterile needle for each injection. Rotate your injection sites (e.g., abdomen, thigh, upper arm) to prevent lipohypertrophy (lumps under the skin). Inject insulin into the subcutaneous tissue (the layer of fat under the skin), not into muscle. If you're unsure about the correct technique, ask your healthcare provider to demonstrate. Consistent injection technique ensures consistent absorption of the insulin.
• **Monitor Your Blood Sugar Regularly:** Frequent blood sugar monitoring is essential when using insulin. Check your blood sugar levels before meals, two hours after meals, and at bedtime, or as directed by your doctor. Keep a log of your blood sugar readings to help you and your doctor identify patterns and adjust your insulin dosage as needed. Understanding how food, exercise, and illness affect your blood sugar will improve your diabetes management.
• **Be Prepared for Hypoglycemia (Low Blood Sugar):** Always carry a source of fast-acting carbohydrates (e.g., glucose tablets, juice, hard candies) with you in case of hypoglycemia. Learn to recognize the symptoms of low blood sugar, which may include sweating, shakiness, dizziness, hunger, confusion, and irritability. Treat low blood sugar immediately. If you experience frequent or severe hypoglycemia, consult your doctor to adjust your insulin regimen.

• LUPISULIN M 30/70 can interact with food, primarily affecting blood sugar levels. It's crucial to maintain a consistent meal schedule and carbohydrate intake. Irregular eating habits or significant changes in diet can lead to hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar). Consult your doctor or diabetes educator for personalized dietary advice tailored to your LUPISULIN M 30/70 regimen. Alcohol consumption can also significantly impact blood sugar levels and should be discussed with your healthcare provider.