ISTAVEL EMPA 25MG TABLET 10'S
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ISTAVEL EMPA 25MG TABLET 10'S
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ISTAVEL EMPA 25MG TABLET 10'S

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ISTAVEL EMPA 25MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

220

₹187

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Tablet

10

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About ISTAVEL EMPA 25MG TABLET 10'S

  • ISTAVEL EMPA 25MG TABLET 10'S is a medication combining two active ingredients, sitagliptin and empagliflozin, designed to manage blood sugar levels in adults with type 2 diabetes. It is typically used when diet and exercise alone are not sufficient to control blood glucose.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the amount of incretin hormones released by the intestine. These hormones help to increase insulin release after a meal and decrease the amount of glucose produced by the liver. By enhancing the effects of incretin hormones, sitagliptin helps to lower blood sugar levels, particularly after meals.
  • Empagliflozin is an SGLT2 inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated from the body through urine. This mechanism not only lowers blood sugar levels but can also provide additional benefits such as weight loss and blood pressure reduction in some patients.
  • ISTAVEL EMPA is usually taken once daily, with or without food, as directed by your healthcare provider. It’s important to follow the prescribed dosage and timing for optimal results. Regular monitoring of blood sugar levels is necessary while taking this medication to ensure it is effectively managing your diabetes.
  • This medication offers a dual approach to managing type 2 diabetes by addressing different pathways involved in blood sugar regulation. Always consult with your doctor or pharmacist for personalized advice on managing your diabetes and whether ISTAVEL EMPA is suitable for your specific health needs.

Uses of ISTAVEL EMPA 25MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Reducing cardiovascular risk (in people with type 2 diabetes)
  • Treatment of Chronic Kidney Disease
  • Treatment of Heart Failure

How ISTAVEL EMPA 25MG TABLET 10'S Works

  • ISTAVEL EMPA 25MG TABLET 10'S is a combination medicine containing two active ingredients: sitagliptin and empagliflozin. These two medications work through different but complementary mechanisms to lower blood sugar levels in individuals with type 2 diabetes. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors), while empagliflozin belongs to a class called SGLT2 inhibitors (sodium-glucose co-transporter 2 inhibitors).
  • Sitagliptin enhances the body's own ability to lower blood sugar. It works by inhibiting the DPP-4 enzyme, which is responsible for breaking down incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1), are released by the intestine in response to food intake. These hormones stimulate the pancreas to release insulin and also reduce the secretion of glucagon (a hormone that raises blood sugar) from the liver. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones, leading to increased insulin release and decreased glucagon secretion, ultimately lowering blood sugar levels, especially after meals.
  • Empagliflozin works independently of insulin to lower blood sugar. It inhibits SGLT2, a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. By blocking SGLT2, empagliflozin causes more glucose to be excreted in the urine, thereby reducing blood sugar levels. This mechanism also leads to a calorie loss, which can contribute to weight loss. Additionally, empagliflozin has been shown to provide cardiovascular benefits in certain patients with type 2 diabetes.
  • In summary, ISTAVEL EMPA 25MG TABLET 10'S combines the complementary actions of sitagliptin and empagliflozin to improve blood sugar control in people with type 2 diabetes. Sitagliptin enhances insulin secretion and reduces glucagon levels through DPP-4 inhibition, while empagliflozin promotes glucose excretion through SGLT2 inhibition. This dual mechanism can lead to more effective blood sugar management compared to using either medication alone. It is important to take this medication as directed by your healthcare provider and to follow their recommendations for diet and exercise.

Side Effects of ISTAVEL EMPA 25MG TABLET 10'SArrow

Possible side effects of ISTAVEL EMPA 25MG Tablet may include: * **Common:** Genital yeast infections (both in men and women), urinary tract infections, increased urination, thirst, nausea. * **Uncommon:** Volume depletion (leading to dizziness or lightheadedness), ketoacidosis (symptoms like nausea, vomiting, abdominal pain, confusion, unusual drowsiness), allergic reactions (rash, itching, swelling). * **Rare:** Fournier's gangrene (a serious infection of the genitals or perineum), kidney problems. **It is important to note:** This is not an exhaustive list. Inform your doctor immediately if you experience any unusual or bothersome symptoms while taking ISTAVEL EMPA 25MG.

Safety Advice for ISTAVEL EMPA 25MG TABLET 10'SArrow

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Allergies

Consult a Doctor

Consult your doctor if you have allergies with ISTAVEL EMPA 25MG TABLET 10'S.

Dosage of ISTAVEL EMPA 25MG TABLET 10'SArrow

  • The recommended dosage of ISTAVEL EMPA 25MG TABLET 10'S is typically one tablet daily. It is crucial to adhere to your physician's specific instructions regarding the timing and method of administration. ISTAVEL EMPA is often prescribed as part of a comprehensive treatment plan for type 2 diabetes, which may include diet and exercise. The tablet should be swallowed whole with a glass of water, and it can be taken with or without food. However, consistency in taking the medication around the same time each day is recommended to maintain stable blood glucose levels.
  • Your doctor will determine the appropriate dosage based on individual factors such as your blood sugar levels, kidney function, and other medications you may be taking. Regular monitoring of your blood glucose levels is essential while taking ISTAVEL EMPA to assess its effectiveness and make any necessary dosage adjustments. It's crucial to inform your healthcare provider about any side effects or concerns you experience while on this medication. Never adjust the dosage yourself without consulting your doctor, as this could lead to adverse effects or suboptimal blood sugar control. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Take 'ISTAVEL EMPA 25MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ISTAVEL EMPA 25MG TABLET 10'S?Arrow

  • If you miss a dose of ISTAVEL EMPA 25MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ISTAVEL EMPA 25MG TABLET 10'S?Arrow

  • Keep ISTAVEL EMPA 25MG TAB 1X10 away from the reach of children and pets.
  • Store ISTAVEL EMPA 25MG TAB 1X10 at room temperature.

Benefits of ISTAVEL EMPA 25MG TABLET 10'SArrow

  • ISTAVEL EMPA 25MG TABLET 10'S is a medication primarily used to manage type 2 diabetes. Its active ingredient, empagliflozin, belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. These inhibitors work by preventing the kidneys from reabsorbing glucose back into the blood, thereby increasing glucose excretion through urine and lowering blood sugar levels.
  • One of the key benefits of ISTAVEL EMPA is its ability to improve glycemic control. By reducing blood sugar levels, it helps to manage the symptoms of diabetes, such as frequent urination, excessive thirst, and unexplained weight loss. Maintaining stable blood sugar levels is crucial in preventing long-term complications associated with diabetes, including nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • Beyond glycemic control, ISTAVEL EMPA offers cardiovascular benefits. Clinical trials have demonstrated that empagliflozin can significantly reduce the risk of cardiovascular events, such as heart attack, stroke, and cardiovascular death, in patients with type 2 diabetes and established cardiovascular disease. This makes ISTAVEL EMPA a valuable option for individuals who are at high risk of cardiovascular complications.
  • ISTAVEL EMPA can also contribute to weight management. Because it promotes glucose excretion through urine, it results in a loss of calories, which can lead to modest weight loss. This can be particularly beneficial for individuals with type 2 diabetes who are overweight or obese, as weight loss can improve insulin sensitivity and overall metabolic health.
  • Furthermore, ISTAVEL EMPA has been shown to have positive effects on kidney health. Studies suggest that it can slow the progression of kidney disease in people with diabetes and kidney problems. By reducing the workload on the kidneys and improving their function, ISTAVEL EMPA can help to preserve kidney health and prevent kidney failure.
  • ISTAVEL EMPA is often used in combination with other diabetes medications, such as metformin, to achieve optimal blood sugar control. It is typically taken once daily, and the dosage may be adjusted based on individual needs and response to treatment. Patients should follow their doctor's instructions carefully and monitor their blood sugar levels regularly while taking ISTAVEL EMPA.
  • It is important to note that ISTAVEL EMPA may not be suitable for everyone. Individuals with severe kidney problems or a history of diabetic ketoacidosis should avoid using this medication. Common side effects of ISTAVEL EMPA include urinary tract infections, yeast infections, and increased urination. Patients should discuss any potential risks and benefits with their healthcare provider before starting treatment with ISTAVEL EMPA.
  • In summary, ISTAVEL EMPA 25MG TABLET 10'S offers a range of benefits for individuals with type 2 diabetes, including improved glycemic control, cardiovascular protection, weight management, and kidney health support. It is an effective medication that can help to prevent diabetes-related complications and improve overall quality of life. Regular monitoring and consultation with a healthcare professional are essential to ensure safe and effective use of ISTAVEL EMPA.

How to use ISTAVEL EMPA 25MG TABLET 10'SArrow

  • ISTAVEL EMPA 25MG TABLET 10'S should be taken orally, usually once daily, with or without food. It's crucial to swallow the tablet whole with a full glass of water, and avoid crushing or chewing it to ensure the medication is released properly. Adherence to your doctor's prescribed dosage and schedule is paramount for optimal results. Consistency in taking the medication at the same time each day will help maintain a steady level of the drug in your system, maximizing its effectiveness.
  • Before starting ISTAVEL EMPA, inform your healthcare provider about any pre-existing medical conditions, especially kidney problems, liver issues, or heart conditions. Also, disclose all other medications you're currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This information is vital to prevent potential drug interactions and ensure the safe use of ISTAVEL EMPA.
  • During treatment with ISTAVEL EMPA, it's essential to monitor your blood sugar levels regularly, particularly if you are also taking other diabetes medications such as insulin or sulfonylureas. Your doctor may adjust the dosage of your other medications to minimize the risk of hypoglycemia (low blood sugar). Be aware of the symptoms of hypoglycemia, such as shakiness, sweating, rapid heartbeat, and confusion, and know how to treat it promptly. If you experience any unusual side effects or have concerns, consult your healthcare provider immediately.
  • Stay hydrated by drinking plenty of water throughout the day, as ISTAVEL EMPA can increase the risk of dehydration. Practice good foot hygiene and inspect your feet regularly for any cuts, blisters, or infections, as diabetes can impair circulation and increase the risk of foot problems. Regular exercise and a healthy diet are also important components of managing diabetes and optimizing the benefits of ISTAVEL EMPA.
  • If you miss a dose of ISTAVEL EMPA, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Store ISTAVEL EMPA at room temperature, away from moisture and heat, and keep it out of reach of children.

Quick Tips for ISTAVEL EMPA 25MG TABLET 10'SArrow

  • Take ISTAVEL EMPA 25MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider, as this could affect your blood sugar control.
  • ISTAVEL EMPA 25MG TABLET 10'S works best when combined with a healthy diet and regular exercise. Follow a meal plan recommended by your doctor or a registered dietitian, and aim for at least 30 minutes of moderate-intensity exercise most days of the week to maximize the benefits of this medication in managing your blood sugar levels.
  • Stay well-hydrated by drinking plenty of water throughout the day while taking ISTAVEL EMPA 25MG TABLET 10'S. Proper hydration helps your kidneys function effectively and supports the removal of excess glucose from your body through urine, which is part of how Empagliflozin works.
  • Monitor your blood sugar levels regularly as directed by your doctor, especially when you first start taking ISTAVEL EMPA 25MG TABLET 10'S. Keeping a record of your blood sugar readings will help you and your healthcare provider assess how well the medication is working for you and make any necessary adjustments to your treatment plan.
  • Be aware of the signs and symptoms of urinary tract infections (UTIs) and yeast infections, such as burning sensation during urination, frequent urination, or unusual discharge. ISTAVEL EMPA 25MG TABLET 10'S can increase your risk of these infections, so it's important to practice good hygiene and seek medical attention promptly if you suspect an infection.

Food Interactions with ISTAVEL EMPA 25MG TABLET 10'SArrow

  • ISTAVEL EMPA 25MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of empagliflozin, the active ingredient in ISTAVEL EMPA. Therefore, you can take it at any time that is convenient for you, regardless of meal times. However, it's important to maintain a consistent dietary pattern as advised by your doctor, especially concerning carbohydrate intake, to manage your blood sugar levels effectively.

FAQs

What is the use of ISTAVEL EMPA 25MG TABLET 10'S?Arrow

ISTAVEL EMPA 25MG TABLET 10'S is used to treat type 2 diabetes mellitus. It helps control blood sugar levels.

How does ISTAVEL EMPA 25MG TABLET 10'S work?Arrow

ISTAVEL EMPA 25MG TABLET 10'S works by removing excess glucose through urine, thus lowering blood sugar levels.

What are the common side effects of ISTAVEL EMPA 25MG TABLET 10'S?Arrow

Common side effects of ISTAVEL EMPA 25MG TABLET 10'S include urinary tract infections, vaginal yeast infections, increased thirst, and increased urination.

Does ISTAVEL EMPA 25MG TABLET 10'S cause weight loss?Arrow

ISTAVEL EMPA 25MG TABLET 10'S may indirectly help with weight loss as it removes excess calories from the body.

How to store ISTAVEL EMPA 25MG TABLET 10'S?Arrow

Store ISTAVEL EMPA 25MG TABLET 10'S at room temperature, away from moisture and direct sunlight.

Is it safe to consume alcohol with ISTAVEL EMPA 25MG TABLET 10'S?Arrow

Consult your doctor before consuming alcohol with ISTAVEL EMPA 25MG TABLET 10'S, as it can affect blood sugar levels.

Is ISTAVEL EMPA 25MG TABLET 10'S safe during pregnancy?Arrow

It is important to consult a doctor before using ISTAVEL EMPA 25MG TABLET 10'S during pregnancy.

Is ISTAVEL EMPA 25MG TABLET 10'S safe during breastfeeding?Arrow

It is important to consult a doctor before using ISTAVEL EMPA 25MG TABLET 10'S during breastfeeding.

What happens if I miss a dose of ISTAVEL EMPA 25MG TABLET 10'S?Arrow

If you miss a dose of ISTAVEL EMPA 25MG TABLET 10'S, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

What are the alternatives to ISTAVEL EMPA 25MG TABLET 10'S?Arrow

Other medications containing empagliflozin are available in the market as alternatives to ISTAVEL EMPA 25MG TABLET 10'S.

Can ISTAVEL EMPA 25MG TABLET 10'S cause kidney problems?Arrow

ISTAVEL EMPA 25MG TABLET 10'S can cause kidney problems in some cases, especially in people with pre-existing kidney disease.

What to do in case of an overdose of ISTAVEL EMPA 25MG TABLET 10'S?Arrow

In case of an overdose of ISTAVEL EMPA 25MG TABLET 10'S, contact a doctor immediately.

Can ISTAVEL EMPA 25MG TABLET 10'S be taken with or without food?Arrow

ISTAVEL EMPA 25MG TABLET 10'S can be taken with or without food, but it is best to take it regularly.

Does ISTAVEL EMPA 25MG TABLET 10'S interact with other medications?Arrow

ISTAVEL EMPA 25MG TABLET 10'S can interact with some medications, so tell your doctor about all your medications.

What should I avoid while taking ISTAVEL EMPA 25MG TABLET 10'S?Arrow

Drink plenty of water to avoid dehydration while taking ISTAVEL EMPA 25MG TABLET 10'S.

References

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European Medicines Agency (EMA) - Istavel EPAR: Provides detailed scientific assessment and regulatory information about Istavel (including active substance Empagliflozin) from the European Medicines Agency.

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DailyMed - Empagliflozin: Provides label information, including composition, pharmacology, and clinical studies related to Empagliflozin products.

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FDA Drugs@FDA: Searchable database for approved drug products, including details on clinical trials, labeling, and regulatory history for Empagliflozin.

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PubMed: A service of the National Library of Medicine, including millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Search for 'Empagliflozin' to find relevant research articles.

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ScienceDirect: A leading source for scientific, technical, and medical research. Search for 'Empagliflozin' for studies on its mechanism of action, clinical efficacy, and safety.

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RxList - Istavel: Provides drug information, including side effects, dosages, and interactions, but primarily for patient information, though it contains some technical details.

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