ZORYL MP 1MG TABLET 15'S
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ZORYL MP 1MG TABLET 15'S
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ZORYL MP 1MG TABLET 15'S

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ZORYL MP 1MG TABLET 15'S

By INTAS PHARMACEUTICALS LIMITED

MRP

244

₹207.4

15 % OFF

₹13.83 Only /

Tablet

10

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About ZORYL MP 1MG TABLET 15'S

  • ZORYL MP 1MG TABLET 15'S is a combination medicine used to treat type 2 diabetes mellitus. It combines three antidiabetic drugs to control high blood sugar levels when diet and exercise alone are not sufficient. This medication helps the body use insulin more effectively, thereby lowering blood glucose.
  • The tablet contains Glimepiride, Metformin, and Pioglitazone. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas, thereby lowering blood glucose. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity. Pioglitazone is a thiazolidinedione that works by increasing the sensitivity of body cells to insulin.
  • ZORYL MP 1MG TABLET 15'S should be taken as prescribed by your doctor. It is usually taken once daily with food to avoid stomach upset. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. It is important to take this medication regularly to get the most benefit. Do not stop taking this medicine without consulting your doctor.
  • Common side effects of ZORYL MP 1MG TABLET 15'S include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. If any of these side effects persist or worsen, inform your doctor. This medication may also cause hypoglycemia (low blood sugar), so it's important to monitor your blood sugar levels regularly and carry a source of glucose with you. This medicine is not recommended for patients with severe kidney or liver disease.

Uses of ZORYL MP 1MG TABLET 15'S

  • Treatment of Type 2 Diabetes Mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling post-meal blood sugar levels
  • Combination therapy with sulfonylureas and metformin

How ZORYL MP 1MG TABLET 15'S Works

  • ZORYL MP 1MG TABLET 15'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients – Glimepiride, Metformin, and Pioglitazone – each addressing different aspects of blood sugar control. Understanding how each component works is crucial to appreciating the overall effectiveness of ZORYL MP.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells, where it's used for energy. By increasing insulin secretion, Glimepiride helps lower blood sugar levels, especially after meals. It essentially enhances the body's natural ability to produce insulin, making it more effective at controlling blood glucose.
  • Metformin, a biguanide, operates through several mechanisms. First, it reduces the amount of glucose produced by the liver. The liver can sometimes overproduce glucose, especially in individuals with type 2 diabetes. Metformin suppresses this process, preventing excessive glucose release into the bloodstream. Second, Metformin improves the body's sensitivity to insulin. This means that cells become more responsive to insulin's signal, allowing glucose to enter them more easily. Finally, Metformin slows down the absorption of glucose from the intestines after a meal, further helping to control post-meal blood sugar spikes.
  • Pioglitazone belongs to a class of drugs called thiazolidinediones (or glitazones). It primarily works by increasing the body's sensitivity to insulin. Similar to Metformin, Pioglitazone helps cells become more responsive to insulin, allowing glucose to enter them more efficiently. However, Pioglitazone achieves this by activating a specific receptor called PPARγ (peroxisome proliferator-activated receptor gamma), which is involved in regulating glucose and lipid metabolism. By activating PPARγ, Pioglitazone enhances insulin sensitivity in muscle, fat, and liver tissues.
  • In essence, ZORYL MP 1MG TABLET 15'S works synergistically by addressing multiple pathways involved in blood sugar control. Glimepiride stimulates insulin release, Metformin reduces liver glucose production and improves insulin sensitivity, and Pioglitazone further enhances insulin sensitivity. This comprehensive approach helps to effectively lower blood sugar levels in individuals with type 2 diabetes, providing better overall glycemic control compared to using a single medication. This combination helps to maintain stable blood sugar levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and its associated complications.

Side Effects of ZORYL MP 1MG TABLET 15'SArrow

ZORYL MP 1MG TABLET 15'S can cause several side effects, although not everyone experiences them. Common side effects may include: Hypoglycemia (low blood sugar), Nausea, Diarrhea, Abdominal pain, Headache, Dizziness. Less common or rare side effects may include: Allergic reactions (rash, itching, swelling), Visual disturbances, Liver problems (jaundice, elevated liver enzymes), Blood disorders (anemia, leukopenia, thrombocytopenia), Weight gain, Constipation, Vomiting, Weakness, Fatigue. This is not an exhaustive list. If you experience any unusual or severe symptoms while taking ZORYL MP 1MG TABLET 15'S, it is crucial to consult your doctor or pharmacist immediately.

Safety Advice for ZORYL MP 1MG TABLET 15'SArrow

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Allergies

Allergies

Do not use ZORYL MP 1MG TABLET 15'S if you are allergic to it or any of its ingredients.

Dosage of ZORYL MP 1MG TABLET 15'SArrow

  • The dosage of 'ZORYL MP 1MG TABLET 15'S' is highly individualized and should be determined by your physician based on your specific blood glucose levels, overall health condition, and response to the medication. It's typically taken orally, once daily, with or without food, but it's best to take it at the same time each day to maintain consistent blood sugar control. The starting dose is usually low, and your doctor may gradually increase it over time to achieve the desired effect. Never adjust the dosage yourself without consulting your healthcare provider.
  • The maximum recommended daily dose should not be exceeded. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
  • It's crucial to monitor your blood glucose levels regularly as directed by your doctor while taking 'ZORYL MP 1MG TABLET 15'S'. This will help them determine if the medication is working effectively and if any dosage adjustments are needed. Also, inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with 'ZORYL MP 1MG TABLET 15'S'.
  • Factors such as kidney function, liver function, and other medical conditions can influence the appropriate dosage of 'ZORYL MP 1MG TABLET 15'S'. Your doctor will take these factors into account when determining the best dosage for you. It's important to attend all scheduled follow-up appointments with your doctor so they can monitor your progress and make any necessary adjustments to your treatment plan. Take 'ZORYL MP 1MG TABLET 15'S' only as per the prescription by your physician only.

What if I miss my dose of ZORYL MP 1MG TABLET 15'S?Arrow

  • If you miss a dose of ZORYL MP 1MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ZORYL MP 1MG TABLET 15'S?Arrow

  • Keep ZORYL MP 1MG TAB 1X15 away from the reach of children and pets.
  • Store ZORYL MP 1MG TAB 1X15 at room temperature.

Benefits of ZORYL MP 1MG TABLET 15'SArrow

  • ZORYL MP 1MG TABLET 15'S is a combination medicine primarily prescribed for managing type 2 diabetes mellitus. Its benefits stem from the synergistic action of its three active ingredients: glimepiride, metformin, and pioglitazone. This combination allows for a more comprehensive approach to controlling blood sugar levels compared to using a single medication.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is crucial for facilitating the uptake of glucose from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps lower blood glucose levels, particularly after meals. This is especially beneficial for individuals whose bodies do not produce enough insulin naturally.
  • Metformin, a biguanide, works through several mechanisms. It primarily reduces glucose production in the liver, decreasing the amount of sugar released into the bloodstream. Additionally, metformin enhances insulin sensitivity, making cells more responsive to insulin's effects. It also slows down the absorption of glucose from the intestines after meals. These combined actions help to control blood sugar levels throughout the day and night. Metformin is also associated with a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications.
  • Pioglitazone, a thiazolidinedione, improves insulin sensitivity in muscle and fat tissues. This allows the body to use insulin more effectively, reducing insulin resistance. By making cells more responsive to insulin, pioglitazone helps lower blood glucose levels and can also improve lipid profiles in some patients. This component addresses the underlying issue of insulin resistance, which is a common problem in type 2 diabetes.
  • The combined effect of these three medications provides several key benefits for individuals with type 2 diabetes. Firstly, it helps to achieve better glycemic control, reducing the risk of long-term complications associated with high blood sugar, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems. Maintaining stable blood sugar levels is essential for overall health and well-being.
  • Secondly, ZORYL MP 1MG TABLET 15'S offers a convenient way to manage diabetes with a single medication, potentially improving adherence and simplifying the treatment regimen. Taking multiple medications can be cumbersome, so a combination tablet can make it easier for patients to stick to their prescribed treatment plan.
  • Thirdly, by targeting different aspects of diabetes (insulin secretion, insulin sensitivity, and glucose production), ZORYL MP 1MG TABLET 15'S can be more effective than using a single medication alone. This multifaceted approach helps to address the complex nature of type 2 diabetes, where multiple factors contribute to elevated blood sugar levels.
  • Finally, it's important to remember that ZORYL MP 1MG TABLET 15'S is most effective when used in conjunction with lifestyle modifications, such as a healthy diet, regular exercise, and weight management. These lifestyle changes can further improve blood sugar control and overall health outcomes. Regular monitoring of blood sugar levels, as recommended by your doctor, is also crucial to ensure the medication is working effectively and to adjust the dosage if needed.

How to use ZORYL MP 1MG TABLET 15'SArrow

  • ZORYL MP 1MG TABLET 15'S should be taken orally, usually once daily, preferably with your first main meal of the day (breakfast or lunch). This helps to synchronize medication release with your body's natural insulin response to food intake. It is crucial to swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed.
  • The dosage of ZORYL MP 1MG TABLET 15'S will be determined by your doctor based on your individual blood sugar levels, response to treatment, and any other medications you may be taking. It is essential to follow your doctor's instructions precisely. Do not change your dose or stop taking the medication without consulting your doctor, even if you feel better.
  • Consistency is key when taking ZORYL MP 1MG TABLET 15'S. Try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • While taking ZORYL MP 1MG TABLET 15'S, it is crucial to monitor your blood sugar levels regularly, as directed by your doctor. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Also, maintain a healthy lifestyle, including a balanced diet and regular exercise, to enhance the effectiveness of the medication and manage your diabetes effectively. Discuss any concerns or side effects with your doctor promptly.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking, as they may interact with ZORYL MP 1MG TABLET 15'S. Pay close attention to potential signs of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, or confusion. Carry a source of fast-acting sugar with you in case of a hypoglycemic episode.

Quick Tips for ZORYL MP 1MG TABLET 15'SArrow

  • Take ZORYL MP 1MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for effective blood sugar control. Skipping doses or altering the schedule can lead to fluctuations in blood glucose levels, potentially diminishing the medication's benefits and increasing the risk of complications.
  • Monitor your blood sugar levels regularly as directed by your doctor or diabetes educator. Keeping a log of your blood glucose readings can help you and your healthcare team assess how well ZORYL MP 1MG TABLET 15'S is working and make necessary adjustments to your treatment plan. Pay attention to patterns and trends in your blood sugar levels, especially before and after meals, and during exercise.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. ZORYL MP 1MG TABLET 15'S can interact with certain medications, potentially affecting its efficacy or increasing the risk of side effects. It is essential to provide your doctor with a complete list of all substances you are taking, including over-the-counter drugs and herbal remedies, to avoid any adverse interactions.
  • Follow a balanced diet and engage in regular physical activity while taking ZORYL MP 1MG TABLET 15'S. This medication works best when combined with lifestyle modifications, such as maintaining a healthy diet and exercising regularly. A balanced diet that is low in processed sugars and saturated fats, combined with regular physical activity can help improve insulin sensitivity and blood sugar control.
  • Be aware of the signs and symptoms of hypoglycemia (low blood sugar) while taking ZORYL MP 1MG TABLET 15'S, such as shakiness, sweating, dizziness, or confusion. Always carry a source of fast-acting glucose, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. It is crucial to recognize the early signs of low blood sugar and take immediate action to prevent it from becoming severe.

Food Interactions with ZORYL MP 1MG TABLET 15'SArrow

  • ZORYL MP 1MG TABLET 15'S is generally taken before meals to ensure optimal absorption and to help regulate blood sugar levels in conjunction with food intake. However, specific interactions with food are minimal. It is advisable to maintain a consistent dietary pattern while on this medication. Consult your doctor or pharmacist for personalized advice regarding diet and ZORYL MP 1MG TABLET 15'S.

FAQs

What is ZORYL MP 1MG TABLET used for?Arrow

ZORYL MP 1MG TABLET is used to lower blood sugar levels in patients with type 2 diabetes mellitus, when diet and exercise alone are not sufficient.

What are the common side effects of ZORYL MP 1MG TABLET?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and hypoglycemia (low blood sugar).

How should I store ZORYL MP 1MG TABLET?Arrow

Store ZORYL MP 1MG TABLET at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

What should I do if I miss a dose of ZORYL MP 1MG TABLET?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can I drink alcohol while taking ZORYL MP 1MG TABLET?Arrow

It is generally not recommended to drink alcohol while taking ZORYL MP 1MG TABLET, as it can increase the risk of hypoglycemia and other side effects.

What should I do in case of an overdose of ZORYL MP 1MG TABLET?Arrow

In case of an overdose, seek immediate medical attention. Symptoms may include severe hypoglycemia, seizures, or loss of consciousness.

Can ZORYL MP 1MG TABLET be used during pregnancy?Arrow

Consult your doctor before using ZORYL MP 1MG TABLET during pregnancy, as it may not be safe for the developing fetus.

Can ZORYL MP 1MG TABLET interact with other medications?Arrow

Yes, ZORYL MP 1MG TABLET can interact with certain medications, such as other diabetes medications, blood pressure medications, and certain pain relievers. Inform your doctor about all the medications you are taking.

How long does it take for ZORYL MP 1MG TABLET to start working?Arrow

The onset of action can vary, but generally, you may start to see the effects of ZORYL MP 1MG TABLET within a few hours of taking it. However, it may take several weeks to see the full effects on blood sugar control.

Is ZORYL MP 1MG TABLET a substitute for insulin?Arrow

No, ZORYL MP 1MG TABLET is not a substitute for insulin. It is used in type 2 diabetes to help the body use insulin more effectively or to stimulate insulin release. Insulin is used in type 1 diabetes and sometimes in type 2 diabetes when oral medications are not sufficient.

Can ZORYL MP 1MG TABLET cause weight gain?Arrow

Weight gain is a potential side effect of ZORYL MP 1MG TABLET, particularly if hypoglycemia occurs and is treated with sugary foods or drinks. Consult your doctor or dietician for advice on managing your weight.

What are the symptoms of hypoglycemia and how to treat it?Arrow

Symptoms of hypoglycemia include shakiness, sweating, dizziness, hunger, and confusion. Treat it by consuming a quick source of sugar, such as glucose tablets, juice, or candy, and then follow with a longer-acting carbohydrate source like crackers or a piece of fruit.

Does ZORYL MP 1MG TABLET affect kidney function?Arrow

ZORYL MP 1MG TABLET can potentially affect kidney function, especially in patients with pre-existing kidney problems. Regular monitoring of kidney function is recommended while taking this medication.

Are there any specific dietary recommendations while taking ZORYL MP 1MG TABLET?Arrow

While taking ZORYL MP 1MG TABLET, it is important to follow a consistent and balanced diet. Avoid skipping meals and limit your intake of sugary foods and drinks. Consult with a registered dietitian for personalized dietary advice.

Can I take ZORYL MP 1MG TABLET before surgery?Arrow

It is crucial to inform your doctor and surgeon that you are taking ZORYL MP 1MG TABLET before any surgery. They may advise you to temporarily discontinue the medication before the procedure to manage blood sugar levels and reduce the risk of complications.

References

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DrugBank: Glimepiride. Provides detailed information on Glimepiride, including its mechanism of action, pharmacokinetics, and interactions.

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FDA Label: Amaryl (Glimepiride). Contains prescribing information approved by the U.S. Food and Drug Administration for Glimepiride.

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National Center for Biotechnology Information (NCBI): Efficacy and safety of glimepiride in the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis. Offers a comprehensive review of the effectiveness and safety of glimepiride.

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Electronic Medicines Compendium (eMC): Glimepiride Tablets. Provides summary of product characteristics for glimepiride tablets.

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UpToDate: Glimepiride drug information. Contains drug information on Glimepiride.

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