AMARYL MP1 TABLET 20'S
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AMARYL MP1 TABLET 20'S
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AMARYL MP1 TABLET 20'S

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AMARYL MP1 TABLET 20'S

By SANOFI INDIA LIMITED

MRP

300.86

₹255.73

15 % OFF

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About AMARYL MP1 TABLET 20'S

  • AMARYL MP1 Tablet 20's is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It combines three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to achieve better glycemic control.
  • Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose get from your blood into your cells for energy. By increasing insulin release, glimepiride helps lower blood sugar levels.
  • Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues, so that your body uses insulin more effectively. It also reduces the absorption of glucose from the intestines.
  • Pioglitazone is a thiazolidinedione that improves insulin sensitivity in muscle and fat tissues. This allows cells to use insulin more effectively, which lowers blood sugar levels. Pioglitazone also helps to reduce glucose production in the liver.
  • This combination of medications provides a comprehensive approach to managing blood sugar levels by addressing multiple factors that contribute to high blood sugar. AMARYL MP1 Tablet 20's is typically prescribed when diet, exercise, and single-agent therapy are not sufficient to achieve adequate blood sugar control. It is important to take this medication exactly as prescribed by your doctor and to follow a healthy diet and exercise plan to maximize its effectiveness. Regular monitoring of blood sugar levels is also essential while taking this medication.
  • Before taking AMARYL MP1 Tablet 20's, it is important to inform your doctor about any other medical conditions you have, especially kidney disease, liver disease, heart problems, or a history of bladder cancer. This medication may not be suitable for everyone, and your doctor will determine if it is the right choice for you based on your individual health profile. Possible side effects may include hypoglycemia (low blood sugar), weight gain, and gastrointestinal disturbances. If you experience any unusual or severe side effects, contact your doctor immediately.

Uses of AMARYL MP1 TABLET 20'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Supportive with diet and exercise
  • Increasing insulin sensitivity

How AMARYL MP1 TABLET 20'S Works

  • AMARYL MP1 Tablet 20's is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to lower blood glucose levels and improve overall glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It stimulates the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) enter cells to be used for energy. By increasing insulin secretion, glimepiride helps lower blood sugar levels, particularly after meals.
  • Metformin is a biguanide that works primarily by reducing the amount of glucose produced by the liver. It also increases the sensitivity of muscle cells to insulin, allowing them to utilize glucose more effectively. Additionally, metformin slows down the absorption of glucose from the intestines after a meal. Unlike sulfonylureas, metformin does not stimulate insulin release, which minimizes the risk of hypoglycemia (low blood sugar) when used alone.
  • Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in peripheral tissues, such as fat and muscle. It works by activating a nuclear receptor called PPARγ (peroxisome proliferator-activated receptor gamma), which regulates the expression of genes involved in glucose and lipid metabolism. By improving insulin sensitivity, pioglitazone helps the body use insulin more effectively, leading to lower blood sugar levels.
  • In summary, AMARYL MP1 Tablet 20's works through a triple-pronged approach: glimepiride stimulates insulin release, metformin reduces glucose production by the liver and enhances insulin sensitivity, and pioglitazone further improves insulin sensitivity in peripheral tissues. This combination helps to address the multiple factors that contribute to high blood sugar levels in type 2 diabetes, providing comprehensive glycemic control when diet and exercise alone are not sufficient. Regular monitoring of blood sugar levels and adherence to the prescribed dosage are crucial for optimal results and to minimize potential side effects. Always consult with your healthcare provider for personalized advice and management of your diabetes.

Side Effects of AMARYL MP1 TABLET 20'SArrow

Common side effects of Amaryl MP1 Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), and skin rash. Less common but potentially serious side effects include liver problems (jaundice, dark urine, persistent fatigue), blood disorders (unexplained bleeding or bruising, sore throat, fever), severe allergic reactions (hives, swelling, difficulty breathing), lactic acidosis (muscle cramps, rapid breathing, stomach pain), and vision changes. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for AMARYL MP1 TABLET 20'SArrow

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Allergies

Allergies

Do not use if you are allergic to AMARYL MP1 TABLET 20'S or any of its ingredients.

Dosage of AMARYL MP1 TABLET 20'SArrow

  • The dosage of AMARYL MP1 TABLET 20'S is highly individualized and should be determined by your physician based on your blood glucose levels, overall health condition, and response to treatment. It is typically taken once daily, with or immediately before the first main meal of the day. Starting dose is usually 1mg per day
  • The maximum recommended daily dose of AMARYL MP1 TABLET 20'S is 8mg. Dosage adjustments should be made gradually, usually in increments of 1mg, at intervals of one to two weeks, based on blood glucose monitoring. It's crucial to adhere to your doctor's instructions meticulously. Do not exceed the prescribed dose, and do not alter the dosage without consulting your physician.
  • If you miss a dose of AMARYL MP1 TABLET 20'S, do not double your next dose to compensate. Instead, take your next dose at the regularly scheduled time. Regularly monitor your blood glucose levels as directed by your doctor. Consistent monitoring helps in adjusting the dosage to achieve optimal blood sugar control.
  • Factors like changes in diet, exercise, or other medications can affect your blood sugar levels and may necessitate dosage adjustments. Always inform your doctor about any changes in your lifestyle or any other medications you are taking. Impaired kidney or liver function may also require dosage adjustments, so it is important to inform your doctor about any pre-existing medical conditions. Take 'AMARYL MP1 TABLET 20'S' only as per the prescription by your physician only.

What if I miss my dose of AMARYL MP1 TABLET 20'S?Arrow

  • If you miss a dose of AMARYL MP1 TABLET 20'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store AMARYL MP1 TABLET 20'S?Arrow

  • Keep AMARYL MP1 TAB 1X20 away from the reach of children and pets.
  • Store AMARYL MP1 TAB 1X20 at room temperature.

Benefits of AMARYL MP1 TABLET 20'SArrow

  • AMARYL MP1 TABLET 20'S is a combination medication designed to effectively manage type 2 diabetes mellitus. This comprehensive treatment approach offers several key benefits for patients seeking optimal blood sugar control. One of the primary benefits is its ability to lower blood glucose levels through multiple mechanisms of action. The components work synergistically to ensure better glycemic control compared to using a single drug.
  • Amaryl, one of the active ingredients, stimulates the pancreas to release more insulin. Insulin is crucial for facilitating the uptake of glucose from the bloodstream into cells, where it can be used for energy. This helps to reduce high blood sugar levels, particularly after meals. By enhancing insulin secretion, AMARYL MP1 TABLET 20'S ensures that the body can effectively utilize the glucose from the food you consume, preventing it from accumulating in the blood.
  • Metformin, another key ingredient, works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues. This means the liver produces less glucose, and the body's cells become more responsive to insulin, allowing them to absorb glucose more efficiently. The combined action of Amaryl and Metformin addresses both insulin deficiency and insulin resistance, which are common issues in type 2 diabetes.
  • Pioglitazone, the third component, further enhances insulin sensitivity in muscle and fat tissues and reduces hepatic glucose output. This helps lower blood sugar levels and improve overall metabolic control. Pioglitazone also has beneficial effects on lipid profiles and can contribute to reducing cardiovascular risk factors associated with diabetes.
  • By combining these three medications, AMARYL MP1 TABLET 20'S offers a comprehensive approach to managing blood sugar levels. This can lead to improved HbA1c levels, which is a measure of long-term blood sugar control. Maintaining healthy HbA1c levels reduces the risk of developing diabetes-related complications, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular disease.
  • Furthermore, AMARYL MP1 TABLET 20'S can help reduce the need for multiple medications, simplifying the treatment regimen and improving patient compliance. A single tablet combining three active ingredients makes it easier for patients to adhere to their prescribed treatment plan. This can lead to better overall health outcomes and an improved quality of life.
  • In addition to its blood sugar-lowering effects, AMARYL MP1 TABLET 20'S may also have other benefits, such as improving cholesterol levels and reducing blood pressure. These additional benefits can further contribute to reducing the risk of cardiovascular complications associated with diabetes. It's important to note that while AMARYL MP1 TABLET 20'S offers numerous benefits, it should be used in conjunction with a healthy diet and regular exercise to achieve optimal results. Lifestyle modifications play a crucial role in managing type 2 diabetes, and medication should be seen as a complement to these efforts.
  • Patients should also be aware of potential side effects, such as hypoglycemia (low blood sugar), and should monitor their blood sugar levels regularly as directed by their healthcare provider. Regular check-ups and communication with your doctor are essential to ensure the safe and effective use of AMARYL MP1 TABLET 20'S.

How to use AMARYL MP1 TABLET 20'SArrow

  • AMARYL MP1 Tablet 20's is designed to help manage blood sugar levels in adults with type 2 diabetes, especially when diet and exercise alone are not enough. It's crucial to take this medication exactly as your doctor prescribes. The usual starting dose is one tablet daily, taken with your first main meal of the day, usually breakfast. This helps to prevent low blood sugar levels (hypoglycemia) that can sometimes occur with this medication.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your body. Taking it at the same time each day will help you remember to take it regularly and maintain a consistent level of medication in your bloodstream. It is imperative to strictly adhere to the prescribed dosage and schedule.
  • Your doctor may adjust your dose over time based on your blood sugar levels and how well you respond to the medication. It's important to monitor your blood sugar regularly, as directed by your healthcare provider, and report any unusual symptoms or side effects to your doctor promptly. Regular blood tests will be needed while you are taking this medicine.
  • AMARYL MP1 Tablet 20's works best when combined with a healthy diet and regular exercise. Follow the dietary and exercise recommendations provided by your doctor or a registered dietitian. Factors like stress, illness, or changes in activity level can affect your blood sugar levels, so close monitoring is essential during these times. Make sure to inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking to avoid any potential interactions.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Always keep AMARYL MP1 Tablet 20's in its original container, stored at room temperature, away from moisture and heat, and out of the reach of children. Do not use the medication if the expiry date has passed. It is recommended to consult your doctor if you have any queries about usage.

Quick Tips for AMARYL MP1 TABLET 20'SArrow

  • Take AMARYL MP1 TABLET 20'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this can lead to fluctuations in your blood sugar levels and potential complications. Consistency is key for optimal management of diabetes.
  • Monitor your blood glucose levels regularly, especially when starting AMARYL MP1 TABLET 20'S or if there are changes in your diet, exercise routine, or other medications. Keeping a record of your blood sugar readings can help you and your doctor adjust your treatment plan as needed for better control.
  • Follow a balanced diet plan that is recommended by your doctor or a registered dietitian. Pay attention to carbohydrate intake and portion sizes. Combine AMARYL MP1 TABLET 20'S with a healthy eating plan to maximize its effectiveness in managing your blood sugar levels. Avoid excessive sugar and processed foods.
  • Engage in regular physical activity. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Exercise helps improve insulin sensitivity and can lower blood sugar levels. Always check with your doctor before starting a new exercise program, especially if you have any other health conditions.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, confusion, and dizziness. Carry a quick source of sugar, like glucose tablets or juice, with you at all times in case you experience these symptoms. Understanding how to recognize and treat hypoglycemia is crucial when taking AMARYL MP1 TABLET 20'S, as it can help you respond promptly and prevent serious complications.

Food Interactions with AMARYL MP1 TABLET 20'SArrow

  • Amaryl MP1 Tablet 20's should be taken with food, preferably with the first main meal of the day, to minimize the risk of hypoglycemia (low blood sugar).
  • Avoid skipping meals while taking this medication, as this can increase the risk of hypoglycemia.
  • Be cautious about consuming alcohol while taking Amaryl MP1 Tablet 20's, as alcohol can potentiate the blood-sugar-lowering effect of the medication.
  • Maintain a consistent carbohydrate intake throughout the day to help stabilize blood sugar levels.

FAQs

What is Amaryl MP1 Tablet 20'S?Arrow

Amaryl MP1 Tablet 20'S is a medication used to treat type 2 diabetes. It contains a combination of Glimepiride, Metformin, and Pioglitazone.

What is Amaryl MP1 Tablet 20'S used for?Arrow

Amaryl MP1 Tablet 20'S is used to control high blood sugar levels in people with type 2 diabetes.

How does Amaryl MP1 Tablet 20'S work?Arrow

Amaryl MP1 Tablet 20'S works in three ways: it increases the amount of insulin released by the pancreas, makes the body more sensitive to insulin, and decreases the amount of glucose produced by the liver.

What are the common side effects of Amaryl MP1 Tablet 20'S?Arrow

Common side effects of Amaryl MP1 Tablet 20'S include nausea, vomiting, diarrhea, and stomach pain.

Is Amaryl MP1 Tablet 20'S safe during pregnancy?Arrow

The safety of Amaryl MP1 Tablet 20'S during pregnancy has not been established. Therefore, it is important to talk to your doctor if you are pregnant or planning to become pregnant.

Is Amaryl MP1 Tablet 20'S safe during breastfeeding?Arrow

It is not known whether Amaryl MP1 Tablet 20'S passes into breast milk. Therefore, it is important to talk to your doctor if you are breastfeeding.

What should I do if I miss a dose of Amaryl MP1 Tablet 20'S?Arrow

If you miss a dose of Amaryl MP1 Tablet 20'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can Amaryl MP1 Tablet 20'S interact with other medications?Arrow

Yes, Amaryl MP1 Tablet 20'S can interact with other medications. It is important to tell your doctor if you are taking any other medications, especially insulin, sulfonylureas, and beta-blockers.

How should I store Amaryl MP1 Tablet 20'S?Arrow

Store Amaryl MP1 Tablet 20'S at room temperature, away from heat and moisture.

What are the symptoms of an overdose of Amaryl MP1 Tablet 20'S?Arrow

Symptoms of an overdose of Amaryl MP1 Tablet 20'S include low blood sugar (hypoglycemia), nausea, vomiting, dizziness, and fainting.

Can I drink alcohol while taking Amaryl MP1 Tablet 20'S?Arrow

Drinking alcohol while taking Amaryl MP1 Tablet 20'S can increase the risk of low blood sugar. You should avoid or limit alcohol consumption.

What dietary precautions should I take while taking Amaryl MP1 Tablet 20'S?Arrow

While taking Amaryl MP1 Tablet 20'S, it is important to eat a healthy diet and exercise regularly.

What are other brands of Glimepiride?Arrow

Some other brands of Glimepiride include Amaryl, Glimy, and Gluconorm.

What are other brands of Metformin?Arrow

Some other brands of Metformin include Glucophage, Glycomet, and Metrol.

What are other brands of Pioglitazone?Arrow

Some other brands of Pioglitazone include Actos and Pionorm.

References

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FDA drug label for Metformin and Glimepiride combination product (AMARYL MP1 contains these ingredients). Provides information on clinical studies, indications, dosage, contraindications, warnings, precautions, adverse reactions, and drug interactions. This is technical information about a drug containing the same active ingredients.

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DrugBank entry for Glimepiride. DrugBank provides detailed information on drug chemistry, pharmacology, pharmacokinetics, interactions, and therapeutic uses. Glimepiride is one of the active ingredients in AMARYL MP1.

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DrugBank entry for Metformin. This database provides detailed information regarding the chemistry, mechanism of action, pharmacology, interactions, and uses of Metformin, an ingredient of AMARYL MP1.

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PubMed Central is a free archive of biomedical and life sciences literature. Searching for 'glimepiride metformin combination' will yield research articles. Specific articles would need to be evaluated for relevance to AMARYL MP1.

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European Medicines Agency website. Searchable database of medicines authorized in the EU. May contain assessment reports or other technical documents related to Glimepiride and Metformin containing products, including information on clinical trials and safety.

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ScienceDirect is a large database of scientific, technical and medical research. Searching for 'glimepiride metformin' returns research papers on their pharmacology, clinical use and other aspects.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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