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ADVAGRAF 0.5MG CAPSULE 10'S
ADVAGRAF 0.5MG CAPSULE 10'S
By ASTELLAS PHARMA INC
MRP
₹
511
₹511
₹51.1 Only /
CAPSULECheck Delivery
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Composition
Product Details
About ADVAGRAF 0.5MG CAPSULE 10'S
- ADVAGRAF 0.5MG CAPSULE 10'S contains the active substance Tacrolimus. It belongs to a class of medications known as calcineurin inhibitors and functions as an immunosuppressant. This capsule is used in conjunction with other medications to prevent the rejection of transplanted organs in individuals who have undergone liver, kidney, heart, or other organ transplants. It is also prescribed to modulate your body's immune response, thereby facilitating the acceptance of the transplanted organ.
- Before taking ADVAGRAF 0.5MG CAPSULE 10'S, it's crucial to inform your physician if you have any allergies to tacrolimus or any of the other components of this medication. Also, disclose any allergies you have to any group of antibiotics. Before starting treatment, notify your doctor if you have a history of liver or heart disease. Immediately inform your physician if you experience symptoms such as fever, bruising under the skin (possibly appearing as red dots), unexplained fatigue, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, or seizures after taking this medicine. These could be signs of a serious adverse reaction and require immediate medical attention.
- While taking ADVAGRAF 0.5MG CAPSULE 10'S, limit your exposure to sunlight and UV light by wearing appropriate protective clothing and using sunscreen with a high sun protection factor. This precaution is necessary due to the potential risk of malignant skin changes associated with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you experience diarrhea for more than a day. If you require any vaccinations, consult your doctor beforehand to ensure they are safe and appropriate for you while you are taking this medication. Regular monitoring and communication with your healthcare provider are essential during treatment with this medication.
- Furthermore, it's important to maintain good hydration and nutrition while taking ADVAGRAF 0.5MG CAPSULE 10'S. Discuss any concerns you have with your doctor or pharmacist. They can provide personalized advice and address any specific questions related to your health condition and treatment plan. Never adjust the dosage of your medication without consulting your healthcare provider.
Uses of ADVAGRAF 0.5MG CAPSULE 10'S
- Help prevent the body from rejecting transplanted organs after an organ transplant surgery.
Side Effects of ADVAGRAF 0.5MG CAPSULE 10'S
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Swelling in the arm or leg
- Hair loss
- Itchy skin
- Constipation, diarrhea
- Nausea, vomiting
- Anemia
- Headache
- Cough
- Increased or decreased heartbeats
- GI bleeding
- Liver Injury
- Seizure
- Acute kidney failure
- Lung infection or respiratory problems
Safety Advice for ADVAGRAF 0.5MG CAPSULE 10'S

Pregnancy
CONSULT YOUR DOCTORBased on animal studies, ADVAGRAF 0.5MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.
Dosage of ADVAGRAF 0.5MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with ADVAGRAF 0.5MG CAPSULE 10'S based on your specific medical condition, its severity, and various other individual factors. It is crucial to strictly adhere to your doctor's instructions regarding the use of this medication. Never attempt to alter the dosage or frequency of administration without consulting your healthcare provider.
- Always take ADVAGRAF 0.5MG CAPSULE 10'S exactly as prescribed. Avoid opening, breaking, crushing, or chewing the capsules, as this could affect how the medication is absorbed and utilized by your body. Instead, swallow the capsule whole with a full glass of water to ensure it reaches your stomach intact.
- For optimal absorption and effectiveness, it is recommended to take ADVAGRAF 0.5MG CAPSULE 10'S on an empty stomach. This means taking it either at least one hour before a meal or waiting for a period of two to three hours after eating. This timing helps to minimize any potential interactions between the medication and food, ensuring that you receive the full therapeutic benefit.
How to store ADVAGRAF 0.5MG CAPSULE 10'S?
- Keep ADVAGRAF 0.5MG CAP 1X10 away from the reach of children and pets.
- Store ADVAGRAF 0.5MG CAP 1X10 at room temperature.
Benefits of ADVAGRAF 0.5MG CAPSULE 10'S
- ADVAGRAF 0.5MG CAPSULE 10'S is a medication that helps to prevent the body from rejecting a transplanted organ, such as a kidney, liver, or heart. It achieves this by suppressing the activity of the immune system.
- The capsule works by targeting specific immune cells called T lymphocytes. It inhibits their activation and proliferation, which are crucial steps in mounting an immune response against the transplanted organ.
- Furthermore, ADVAGRAF 0.5MG CAPSULE 10'S also affects the B cells, another type of immune cell. It reduces the T-helper-cell-dependent B-cell response, further dampening the overall immune reaction.
- At the molecular level, the medication binds to a protein inside the immune cells called FKBP-12. This combination forms a complex known as tacrolimus-FKBP, which then inhibits calcineurin phosphatase, an enzyme essential for T cell activation. By blocking this enzyme, the drug effectively prevents the formation of functional T cells, leading to a suppressed immune response and reducing the risk of organ rejection.
How to use ADVAGRAF 0.5MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with ADVAGRAF 0.5MG CAPSULE 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to always take ADVAGRAF 0.5MG CAPSULE 10'S exactly as prescribed by your doctor.
- Administering this medication correctly is essential for optimal results. Do not attempt to open, break, crush, or chew the capsules. Instead, swallow the capsule whole with a glass of water to ensure it is properly absorbed. Consistency in how you take the medication will aid its effectiveness.
- For best absorption and to maximize the benefits of ADVAGRAF 0.5MG CAPSULE 10'S, take these capsules on an empty stomach. This generally means taking it at least 1 hour before a meal or waiting 2 to 3 hours after eating before taking the capsule. This ensures that food does not interfere with the absorption of the medication into your system, helping it to work as effectively as possible.
FAQs
What if I missed a dose of ADVAGRAF 0.5MG CAPSULE 10'S?

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose
What should you not use with ADVAGRAF 0.5MG CAPSULE 10'S?

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.
How long do I need to take ADVAGRAF 0.5MG CAPSULE 10'S after a transplant?

The duration of ADVAGRAF 0.5MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, ADVAGRAF 0.5MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.
Can ADVAGRAF 0.5MG CAPSULE 10'S increase the risk of infections?

Yes, ADVAGRAF 0.5MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.
Can ADVAGRAF 0.5MG CAPSULE 10'S affect kidney function?

ADVAGRAF 0.5MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.
Should I follow any dietary restrictions while taking ADVAGRAF 0.5MG CAPSULE 10'S?

ADVAGRAF 0.5MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.
What are the interactions of ADVAGRAF 0.5MG CAPSULE 10'S with other drugs?

There are no known interactions of ADVAGRAF 0.5MG CAPSULE 10'S with other drugs.
What advice should I follow while taking ADVAGRAF 0.5MG CAPSULE 10'S?

Do not eat grapefruit or drink grapefruit juice while you are using ADVAGRAF 0.5MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.
What is ADVAGRAF 0.5MG CAPSULE 10'S made of?

ADVAGRAF 0.5MG CAPSULE 10'S is made from the molecule/combination called TACROLIMUS.
For what ailments/diseases/conditions is ADVAGRAF 0.5MG CAPSULE 10'S prescribed?

ADVAGRAF 0.5MG CAPSULE 10'S is prescribed for Nephrology and Infectious Diseases.
Ratings & Review
All drugs available good service
Jayvadan Lalpara
•
Reviewed on 23-01-2024
(5/5)
Good representation and good communication to the cx very helpfull
Sunny Mack
•
Reviewed on 02-02-2024
(5/5)
Best generic alternative. Great quality, great prices
Deep Patel
•
Reviewed on 01-09-2023
(5/5)
One stop solution for medicine
Chintan Joshi
•
Reviewed on 16-01-2024
(5/5)
Proper medicine at big saving rate
Mukesh Jain
•
Reviewed on 24-01-2024
(5/5)
Marketer / Manufacturer Details
ASTELLAS PHARMA INC
Country of Origin -
India
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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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