KEYGRAF 0.5 CAPSULE 10'S
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KEYGRAF 0.5 CAPSULE 10'S
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KEYGRAF 0.5 CAPSULE 10'S

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KEYGRAF 0.5 CAPSULE 10'S

By ANTHEM BIOPHARMA

MRP

206.4

₹185.76

10 % OFF

₹18.58 Only /

CAPSULE

10

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Product DetailsArrow

About KEYGRAF 0.5 CAPSULE 10'S

  • KEYGRAF 0.5 CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. KEYGRAF 0.5 CAPSULE 10'S works by suppressing the activity of certain immune cells, preventing them from attacking the transplanted organ.
  • Before taking KEYGRAF 0.5 CAPSULE 10'S, inform your physician if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report to your physician if you are allergic to any antibiotic group. It is important to inform your doctor if you have or had a liver or heart disease before starting the treatment with this medication. Also, notify your physician immediately if you develop symptoms such as fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. These could be signs of serious side effects.
  • During the treatment with KEYGRAF 0.5 CAPSULE 10'S, it is recommended to limit exposure to sunlight and UV light by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor before receiving them, as this medicine can affect the way vaccines work. Regular monitoring and check-ups are necessary while on this medication to assess its effectiveness and to monitor for any potential side effects.

Uses of KEYGRAF 0.5 CAPSULE 10'S

  • Help the body accept a transplanted organ by preventing rejection.

Side Effects of KEYGRAF 0.5 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for KEYGRAF 0.5 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, KEYGRAF 0.5 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of KEYGRAF 0.5 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with KEYGRAF 0.5 CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's prescription when taking KEYGRAF 0.5 CAPSULE 10'S.
  • To ensure optimal absorption and effectiveness, swallow the capsule whole with a glass of water. Avoid opening, breaking, crushing, or chewing the capsules, as this could alter the way the medication is released into your system.
  • For the best results, take KEYGRAF 0.5 CAPSULE 10'S on an empty stomach. This means consuming it either at least one hour before a meal or waiting for two to three hours after eating. This timing helps to minimize potential interactions with food and maximize the drug's absorption into your bloodstream, leading to improved therapeutic outcomes.
  • Consistency in timing is important. Try to take KEYGRAF 0.5 CAPSULE 10'S at the same time each day to maintain a steady level of medication in your body. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store KEYGRAF 0.5 CAPSULE 10'S?Arrow

  • Keep KEYGRAF 0.5MG CAP 1X10 away from the reach of children and pets.
  • Store KEYGRAF 0.5MG CAP 1X10 at room temperature.

Benefits of KEYGRAF 0.5 CAPSULE 10'SArrow

  • KEYGRAF 0.5 CAPSULE 10'S is a medication that helps to suppress the immune system. It achieves this by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes. These cells are crucial components of the immune system, and by controlling their activity, KEYGRAF 0.5 CAPSULE 10'S can prevent the body from attacking itself in cases of autoimmune disorders or organ transplantation.
  • The drug's mechanism of action involves binding to a protein inside the cells called FKBP-12. This binding results in the formation of a complex known as tacrolimus-FKBP. This complex then goes on to inhibit calcineurin phosphatase, an enzyme that plays a key role in the signaling pathways that lead to T-cell activation. By blocking this enzyme, KEYGRAF 0.5 CAPSULE 10'S effectively disrupts the process of T-cell formation.
  • Furthermore, KEYGRAF 0.5 CAPSULE 10'S also affects the T-helper-cell-dependent B-cell response. B-cells are another type of immune cell responsible for producing antibodies. By suppressing the activity of T-helper cells, which assist B-cells, KEYGRAF 0.5 CAPSULE 10'S can further dampen the overall immune response. This comprehensive immunosuppressive action makes it valuable in preventing organ rejection after transplantation and managing autoimmune conditions.

How to use KEYGRAF 0.5 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take KEYGRAF 0.5 CAPSULE 10'S exactly as prescribed by your healthcare provider.
  • To ensure proper absorption and effectiveness, do not open, break, crush, or chew the capsules. Swallow the capsule whole with a full glass of water. This medication is best taken on an empty stomach, ideally at least 1 hour before or 2 to 3 hours after meals. This timing helps to optimize the drug's bioavailability.
  • Consistency in timing is key. Try to take KEYGRAF 0.5 CAPSULE 10'S at the same time each day to maintain a stable level of the medication in your system. If you have any questions or concerns about how to take this medication, or if you experience any unusual side effects, consult with your doctor or pharmacist immediately.

FAQs

What if I missed a dose of KEYGRAF 0.5 CAPSULE 10'S?

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Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with KEYGRAF 0.5 CAPSULE 10'S?

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Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take KEYGRAF 0.5 CAPSULE 10'S after a transplant?

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The duration of KEYGRAF 0.5 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, KEYGRAF 0.5 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can KEYGRAF 0.5 CAPSULE 10'S increase the risk of infections?

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Yes, KEYGRAF 0.5 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can KEYGRAF 0.5 CAPSULE 10'S affect kidney function?

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KEYGRAF 0.5 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy

Should I follow any dietary restrictions while taking KEYGRAF 0.5 CAPSULE 10'S?

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KEYGRAF 0.5 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

NULL interaction of KEYGRAF 0.5 CAPSULE 10'S with other drungs

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Always consult your doctor or pharmacist for information about how KEYGRAF 0.5 CAPSULE 10'S interacts with other medications.

What advice should I follow while taking KEYGRAF 0.5 CAPSULE 10'S?

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Do not eat grapefruit or drink grapefruit juice while you are using KEYGRAF 0.5 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is KEYGRAF 0.5 CAPSULE 10'S made of?

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KEYGRAF 0.5 CAPSULE 10'S is made of TACROLIMUS.

For which conditions is KEYGRAF 0.5 CAPSULE 10'S prescribed?

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KEYGRAF 0.5 CAPSULE 10'S is prescribed for ailments such as Nephrology and Infectious Disease.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Reviewed on 05-12-2022

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amit sharma

Reviewed on 17-07-2023

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(5/5)

Visited medkart and it was a great experience with staff and they explains everything about generic medicine. How they r less in cost and both continent and power are same., everyone who buy their monthly medicine from other medicine stores should visit medkart and convert to generic medicine........ Best of luck medkart

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Had a good experience when I went for purchasing medicine. Appreciate the service

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Reviewed on 07-11-2022

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(5/5)

Good staff and all generic medicines are available.👍

DALPAT PARMAR

Reviewed on 19-01-2024

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(5/5)


Marketer / Manufacturer Details

ANTHEM BIOPHARMA

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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