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PANGRAF 0.5MG CAPSULE 10'S
PANGRAF 0.5MG CAPSULE 10'S
By PANACEA BIOTEC LIMITED
MRP
₹
231.39
₹196.68
15 % OFF
₹19.67 Only /
CAPSULE
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Composition
Product Details
About PANGRAF 0.5MG CAPSULE 10'S
- PANGRAF 0.5MG CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. This medication works by suppressing the activity of certain immune cells that would otherwise attack the transplanted organ, thereby preventing rejection.
- Before taking PANGRAF 0.5MG CAPSULE 10'S, it's crucial to inform your healthcare provider about any existing medical conditions, especially liver or heart disease. Also, disclose any allergies you have, particularly to tacrolimus or any other ingredients in the capsule, or to any antibiotic group. It is essential to discuss your complete medical history with your doctor to ensure the safe and effective use of this medicine. Regular monitoring and communication with your healthcare team are vital throughout the treatment period.
- Do not take PANGRAF 0.5MG CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
- While taking PANGRAF 0.5MG CAPSULE 10'S, limit exposure to sunlight and UV light by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them. Close monitoring of kidney function, blood pressure, and blood sugar levels may be necessary during treatment with this medication. Follow your doctor's instructions carefully and attend all scheduled appointments.
Uses of PANGRAF 0.5MG CAPSULE 10'S
- Helps to prevent organ transplant rejections, ensuring the body accepts the new organ.
How PANGRAF 0.5MG CAPSULE 10'S Works
- PANGRAF 0.5MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
- PANGRAF 0.5MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, PANGRAF 0.5MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, PANGRAF 0.5MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of PANGRAF 0.5MG CAPSULE 10'S in skin disorders is not fully understood.
Side Effects of PANGRAF 0.5MG CAPSULE 10'S
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Swelling in the arm or leg
- Hair loss
- Itchy skin
- Constipation, diarrhea
- Nausea, vomiting
- Anemia
- Headache
- Cough
- Increased or decreased heartbeats
- GI bleeding
- Liver Injury
- Seizure
- Acute kidney failure
- Lung infection or respiratory problems
Safety Advice for PANGRAF 0.5MG CAPSULE 10'S
Pregnancy
CONSULT YOUR DOCTORBased on animal studies, PANGRAF 0.5MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.
Dosage of PANGRAF 0.5MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 0.5MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to always take PANGRAF 0.5MG CAPSULE 10'S exactly as prescribed by your healthcare provider. Adhering to their instructions is vital for the medication's effectiveness and your safety.
- Do not attempt to open, break, crush, or chew the capsules. These capsules are designed to be swallowed whole to ensure the medication is released properly in your system. Taking them in any other way could affect how the drug works.
- Swallow the capsule whole with a full glass of water. This helps to ensure that the capsule goes down smoothly and is properly absorbed.
- For optimal absorption, take PANGRAF 0.5MG CAPSULE 10'S on an empty stomach, ideally at least 1 hour before meals or 2 to 3 hours after eating. This timing helps to minimize any potential interactions between the medication and food, ensuring that you receive the full benefit of the drug.
How to store PANGRAF 0.5MG CAPSULE 10'S?
- Keep PANGRAF 0.5MG CAP 1X10 away from the reach of children and pets.
- Store PANGRAF 0.5MG CAP 1X10 at room temperature.
Benefits of PANGRAF 0.5MG CAPSULE 10'S
- PANGRAF 0.5MG CAPSULE 10'S is a powerful immunosuppressant medication that works by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes. This is crucial in preventing the body's immune system from attacking transplanted organs or tissues, thereby reducing the risk of rejection following transplantation.
- The medication's mechanism of action involves binding to an intracellular protein known as FKBP-12. This binding action leads to the formation of a complex called tacrolimus-FKBP. This complex then goes on to inhibit the activity of calcineurin phosphatase, a critical enzyme involved in T-cell activation.
- By inhibiting calcineurin phosphatase, PANGRAF 0.5MG CAPSULE 10'S effectively blocks the signaling pathways that lead to the formation and activation of T cells. This suppression of T-cell activity weakens the overall immune response, making it less likely to attack the transplanted organ. Furthermore, it also suppresses T-helper-cell-dependent B-cell response.
- This targeted approach to immunosuppression helps to prevent organ rejection while minimizing some of the broader, more systemic side effects that can be associated with other types of immunosuppressant drugs. Regular monitoring and close consultation with your healthcare provider are essential to ensure the safe and effective use of PANGRAF 0.5MG CAPSULE 10'S.
How to use PANGRAF 0.5MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 0.5MG CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take PANGRAF 0.5MG CAPSULE 10'S exactly as prescribed by your doctor. Deviating from the prescribed dosage or schedule can affect the medication's effectiveness and potentially lead to adverse effects.
- These capsules are designed to be swallowed whole. Do not attempt to open, break, crush, or chew them, as this could alter the way the medication is released and absorbed by your body. Instead, swallow the capsule whole with a full glass of water to ensure it travels smoothly to your stomach.
- For optimal absorption and effectiveness, it is generally recommended to take PANGRAF 0.5MG CAPSULE 10'S on an empty stomach. This usually means taking it either at least 1 hour before a meal or waiting for 2 to 3 hours after eating. This timing helps to minimize any potential interactions between the medication and food, allowing your body to absorb the full dose properly. If you have any concerns about how to take this medication with food or other medications, talk to your doctor.
FAQs
What if I missed a dose of PANGRAF 0.5MG CAPSULE 10'S?
Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.
What should you not use with PANGRAF 0.5MG CAPSULE 10'S?
Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.
How long do I need to take PANGRAF 0.5MG CAPSULE 10'S after a transplant?
The duration of PANGRAF 0.5MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, PANGRAF 0.5MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.
Can PANGRAF 0.5MG CAPSULE 10'S increase the risk of infections?
Yes, PANGRAF 0.5MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.
Can PANGRAF 0.5MG CAPSULE 10'S affect kidney function?
PANGRAF 0.5MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.
Should I follow any dietary restrictions while taking PANGRAF 0.5MG CAPSULE 10'S?
PANGRAF 0.5MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.
NULL interaction of PANGRAF 0.5MG CAPSULE 10'S with other drungs
There is no known interaction of PANGRAF 0.5MG CAPSULE 10'S with other drugs.
What is the advice related to PANGRAF 0.5MG CAPSULE 10'S?
Do not eat grapefruit or drink grapefruit juice while you are using PANGRAF 0.5MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.
What molecule/combination is used for making PANGRAF 0.5MG CAPSULE 10'S?
TACROLIMUS is molecule/combination used for making PANGRAF 0.5MG CAPSULE 10'S.
For what ailments/diseases/conditions is PANGRAF 0.5MG CAPSULE 10'S prescribed?
{Nephrology,"Infectious Disease"} are ailments/disease/conditions for which PANGRAF 0.5MG CAPSULE 10'S is presecribed.
References
Ratings & Review
Genuine handling person
Naresh Jangid
•
Reviewed on 30-03-2024
(5/5)
Nice discount and best quality medicine generic ..thank you
Mihir Ujjaniya
•
Reviewed on 29-12-2023
(4/5)
Excellent service and support 24/7 Supportive and co operative staff.
Ajay Nayak Dhadkan
•
Reviewed on 13-01-2024
(5/5)
Had a good experience when I went for purchasing medicine. Appreciate the service
Chitrang Shah
•
Reviewed on 07-11-2022
(5/5)
Very good place for medicine allmost all the medicine are available at discounted rate.
Sachin Dodhiwala
•
Reviewed on 10-03-2024
(5/5)
Marketer / Manufacturer Details
PANACEA BIOTEC LIMITED
Country of Origin -
India
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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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