PROGRAF 0.5MG CAPSULE 10'S
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PROGRAF 0.5MG CAPSULE 10'S
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PROGRAF 0.5MG CAPSULE 10'S

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PROGRAF 0.5MG CAPSULE 10'S

By ASTELLAS PHARMA INC

MRP

220

₹209

5 % OFF

₹20.9 Only /

CAPSULE

10

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Product DetailsArrow

About PROGRAF 0.5MG CAPSULE 10'S

  • PROGRAF 0.5MG CAPSULE 10'S contains the active substance Tacrolimus. It belongs to a class of medications known as calcineurin inhibitors and functions as an immunosuppressant. This capsule is prescribed alongside other medications to prevent the rejection of transplanted organs in individuals who have undergone liver, kidney, heart, or other organ transplants. Its primary role is to regulate your body's immune response, thus enabling the acceptance of the transplanted organ. By suppressing the immune system, PROGRAF 0.5MG CAPSULE 10'S helps to prevent the body from attacking the new organ, ensuring its survival and proper function.
  • Before taking PROGRAF 0.5MG CAPSULE 10'S, be aware of the following precautions. Do not use this medication if you have a known allergy to tacrolimus or any of its other ingredients. It's crucial to inform your physician about any existing allergies, particularly to any antibiotic groups. Prior to starting treatment, disclose any history of liver or heart disease to your doctor. It's also important to be vigilant for any adverse reactions while taking this medication. Immediately notify your physician if you experience symptoms such as fever, unexplained bruising under the skin (which may manifest as red dots), unusual fatigue, confusion, yellowing of the skin or eyes, decreased urine output, vision disturbances, or seizures.
  • While taking PROGRAF 0.5MG CAPSULE 10'S, it's essential to minimize exposure to sunlight and UV light by wearing appropriate protective clothing and using a sunscreen with a high sun protection factor. This is due to the increased risk of malignant skin changes associated with immunosuppressive therapy. Diarrhea is a potential side effect of this medicine; inform your physician if you experience diarrhea lasting for more than a day. If you require any vaccinations, consult your doctor before receiving them. This medication can increase your susceptibility to infections, so practicing good hygiene and avoiding contact with sick individuals is essential. Regular monitoring by your healthcare provider is also crucial to assess the effectiveness of the medication and to detect any potential side effects early on.

Uses of PROGRAF 0.5MG CAPSULE 10'S

  • Prevent organ transplant rejections by suppressing the body's immune system, reducing the likelihood of the body attacking the new organ.

Side Effects of PROGRAF 0.5MG CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for PROGRAF 0.5MG CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, PROGRAF 0.5MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of PROGRAF 0.5MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with PROGRAF 0.5MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to strictly adhere to your doctor's instructions regarding the use of this medication. Never attempt to adjust the dosage or frequency of administration without consulting your healthcare provider.
  • To ensure optimal absorption and effectiveness, PROGRAF 0.5MG CAPSULE 10'S should be taken exactly as prescribed. Avoid opening, breaking, crushing, or chewing the capsules, as this could alter the way the medication is released and absorbed into your system. Instead, swallow the capsule whole with a full glass of water.
  • For best results, take PROGRAF 0.5MG CAPSULE 10'S on an empty stomach. Ideally, this means taking it at least one hour before a meal or waiting for two to three hours after eating before taking the capsule. This helps to minimize any potential interactions with food that could affect the drug's absorption. Consistent timing is essential for maintaining stable drug levels in your body and achieving the desired therapeutic effect. If you have any questions or concerns about how to take this medication, please consult your doctor or pharmacist for clarification.

How to store PROGRAF 0.5MG CAPSULE 10'S?Arrow

  • Keep PROGRAF 0.5MG CAP 1X10 away from the reach of children and pets.
  • Store PROGRAF 0.5MG CAP 1X10 at room temperature.

Benefits of PROGRAF 0.5MG CAPSULE 10'SArrow

  • PROGRAF 0.5MG CAPSULE 10'S is a medication that helps to weaken the body's immune system. It achieves this by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes, which are crucial components of the immune response. Additionally, it suppresses the T-helper-cell-dependent B-cell response, further dampening the immune system's activity.
  • The mechanism of action of PROGRAF 0.5MG CAPSULE 10'S involves binding to an intracellular protein known as FKBP-12. This binding results in the formation of a complex called tacrolimus-FKBP. This complex then inhibits the activity of calcineurin phosphatase, a critical enzyme involved in T-cell activation. By inhibiting calcineurin, PROGRAF 0.5MG CAPSULE 10'S effectively blocks the formation of functional T cells.
  • Consequently, the overall immune response is significantly suppressed. This immunosuppressive effect is particularly valuable in preventing the rejection of transplanted organs, as it reduces the likelihood of the body's immune system attacking the foreign tissue. It is also used to treat certain autoimmune disorders where the immune system mistakenly attacks the body's own tissues.

How to use PROGRAF 0.5MG CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with PROGRAF 0.5MG CAPSULE 10'S based on your specific medical condition, its severity, and other individual factors. It is crucial to adhere strictly to your doctor's instructions regarding the use of this medication.
  • Always take PROGRAF 0.5MG CAPSULE 10'S exactly as prescribed. Do not alter the dosage or frequency without consulting your healthcare provider. This medicine is intended for oral administration only.
  • To ensure optimal absorption and effectiveness, swallow the capsules whole with a full glass of water. Avoid opening, breaking, crushing, or chewing the capsules, as this could affect how the medication is released and absorbed into your system.
  • For best results, take PROGRAF 0.5MG CAPSULE 10'S on an empty stomach. This means consuming it either at least 1 hour before a meal or waiting for 2 to 3 hours after eating. This helps to minimize potential interactions with food that could interfere with the drug's absorption.
  • If you have any questions or concerns about how to properly take PROGRAF 0.5MG CAPSULE 10'S, please consult your doctor or pharmacist for clarification.

FAQs

<p style=\"text-align:justify;\">What if I missed a dose of PROGRAF 0.5MG CAPSULE 10'S?</p>

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Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

<p style=\"text-align:justify;\">What should you not use with PROGRAF 0.5MG CAPSULE 10'S?</p>

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Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

<p style=\"text-align:justify;\">How long do I need to take PROGRAF 0.5MG CAPSULE 10'S after a transplant?</p>

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The duration of PROGRAF 0.5MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, PROGRAF 0.5MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

<p style=\"text-align:justify;\">Can PROGRAF 0.5MG CAPSULE 10'S increase the risk of infections?</p>

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Yes, PROGRAF 0.5MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

<p style=\"text-align:justify;\">Can PROGRAF 0.5MG CAPSULE 10'S affect kidney function?</p>

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Prograf 0.5mg Capsule must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

<p style=\"text-align:justify;\">Should I follow any dietary restrictions while taking PROGRAF 0.5MG CAPSULE 10'S?</p>

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Prograf 0.5mg Capsule can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important. 

What are the drug interactions of PROGRAF 0.5MG CAPSULE 10'S?

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There are no known negative interactions of PROGRAF 0.5MG CAPSULE 10'S with other drugs.

What advice should I follow while taking PROGRAF 0.5MG CAPSULE 10'S?

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Do not eat grapefruit or drink grapefruit juice while you are using Prograf 0.5mg Capsule. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly. 

What molecule/combination is used for making PROGRAF 0.5MG CAPSULE 10'S?

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TACROLIMUS is molecule/combination used for making PROGRAF 0.5MG CAPSULE 10'S.

For which ailments/diseases/conditions is PROGRAF 0.5MG CAPSULE 10'S prescribed?

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PROGRAF 0.5MG CAPSULE 10'S is prescribed for ailments/diseases/conditions like Nephrology (kidney-related) and Infectious Diseases.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Marketer / Manufacturer Details

ASTELLAS PHARMA INC

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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