AMIGRAF 0.5 CAPSULE 10'S
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AMIGRAF 0.5 CAPSULE 10'S
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AMIGRAF 0.5 CAPSULE 10'S

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AMIGRAF 0.5 CAPSULE 10'S

By BIOKINDLE LIFESCIENCES PRIVATE LIMITED

MRP

₹

215.63

₹183.28

15 % OFF

₹18.33 Only /

CAPSULE

10

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About AMIGRAF 0.5 CAPSULE 10'S

  • AMIGRAF 0.5 CAPSULE 10'S contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. Tacrolimus works by suppressing the activity of certain immune cells that would otherwise attack the transplanted organ, preventing rejection. It is a crucial medication for individuals undergoing organ transplantation, helping to ensure the long-term success of the transplant.
  • Do not take this AMIGRAF 0.5 CAPSULE 10'S if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. It's vital to provide a complete medical history to your healthcare provider to ensure safe and effective treatment. Discuss any pre-existing conditions, allergies, and medications you are currently taking. This information will help your doctor determine if AMIGRAF 0.5 CAPSULE 10'S is the right choice for you.
  • Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. These symptoms could indicate serious side effects, and prompt medical attention is crucial. Regular monitoring and communication with your healthcare team are essential during treatment with AMIGRAF 0.5 CAPSULE 10'S to detect and manage any potential complications effectively.
  • Limit exposure to sunlight and UV light while consuming AMIGRAF 0.5 CAPSULE 10'S by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them. Immunosuppressants can affect the effectiveness of vaccines, so it's important to coordinate vaccinations with your doctor to ensure optimal protection.

Uses of AMIGRAF 0.5 CAPSULE 10'S

  • Prevent organ transplant rejections. AMIGRAF 0.5 CAPSULE 10'S helps prevent the body from rejecting a newly transplanted organ.

Side Effects of AMIGRAF 0.5 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for AMIGRAF 0.5 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, AMIGRAF 0.5 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of AMIGRAF 0.5 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration based on your specific medical condition, its severity, and other relevant factors. It is crucial to always take AMIGRAF 0.5 CAPSULE 10'S exactly as prescribed by your healthcare provider. Do not attempt to open, break, crush, or chew the capsules. Instead, swallow each capsule whole with a full glass of water.
  • For optimal absorption and effectiveness, take these capsules on an empty stomach. This means consuming them either at least one hour before a meal or waiting for two to three hours after you have eaten. Following this guideline helps ensure that the medication is properly absorbed into your system.
  • Adhering to your doctor's instructions regarding dosage and timing is essential for the medication to work as intended and for you to experience the desired therapeutic benefits. If you have any questions or concerns about how to take AMIGRAF 0.5 CAPSULE 10'S, or if you experience any unexpected side effects, consult with your doctor or pharmacist for clarification and guidance.

How to store AMIGRAF 0.5 CAPSULE 10'S?Arrow

  • Keep AMIGRAF 0.5MG CAP 1X10 away from the reach of children and pets.
  • Store AMIGRAF 0.5MG CAP 1X10 at room temperature.

Benefits of AMIGRAF 0.5 CAPSULE 10'SArrow

  • AMIGRAF 0.5 CAPSULE 10'S is a medication that functions by suppressing the immune system. Its primary action involves inhibiting the activation and proliferation of T-lymphocytes, which are crucial components of the immune response. Additionally, it interferes with the T-helper-cell-dependent B-cell response, further dampening the immune system's activity.
  • The drug achieves this immunosuppression through a specific mechanism. It binds to an intracellular protein known as FKBP-12, forming a complex called tacrolimus-FKBP. This complex then inhibits the activity of calcineurin phosphatase, an enzyme essential for T-cell activation. By blocking calcineurin phosphatase, AMIGRAF 0.5 CAPSULE 10'S effectively prevents the formation of new T cells and reduces the overall immune response.
  • This targeted approach makes AMIGRAF 0.5 CAPSULE 10'S valuable in preventing organ rejection after transplantation, as it selectively weakens the immune system's ability to attack the transplanted organ. It is also used in treating certain autoimmune disorders where an overactive immune system is causing damage to the body's own tissues.

How to use AMIGRAF 0.5 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and treatment duration for AMIGRAF 0.5 CAPSULE 10'S based on your specific medical condition, its severity, and other relevant factors. It's crucial to always follow your doctor's instructions precisely when taking this medication.
  • To ensure optimal absorption and effectiveness, AMIGRAF 0.5 CAPSULE 10'S should be taken on an empty stomach. This means consuming it either at least one hour before a meal or waiting for two to three hours after eating. This helps to minimize potential interactions with food that could affect how the medication is processed by your body.
  • The capsules should be swallowed whole with a glass of water. Avoid opening, breaking, crushing, or chewing them, as this could alter the way the medication is released and absorbed, potentially affecting its efficacy and safety. Taking the capsule whole ensures that the medication is delivered to the appropriate part of your digestive system for optimal absorption.
  • If you have any concerns or questions regarding the proper way to take AMIGRAF 0.5 CAPSULE 10'S, don't hesitate to consult your doctor or pharmacist. They can provide personalized guidance based on your individual health circumstances.

Top Substitutes for AMIGRAF 0.5 CAPSULE 10'S

MedicineManufacturerPack SizeMRPMedkart PriceSavings (%)
TACROLIM 0.5MG CAP 1X10DR REDDY'S LABORATORIES LIMITED1015011324.67
ACOMUSKIN 0.5MG CAP 1X10ACCORD PHARMA101241166.45
XGRAF 0.5MG CAP 1X10APRAZER HEALTHCARE PVT LTD10193.5145.1225
MYLIMUS 0.5MG CAP 1X10MYLAN PHARMACEUTICALS PRIVATE LIMITED10193.52154.8220
TACROTEN 0.5MG CAP 1X10NEUTEN HEALTHCARE10187158.9515
TACSTEAD 0.5MG CAP 1X10STEADFAST MEDISHIELD PRIVATE LIMITED10187.5159.3815
TACLORAN 0.5MG CAP 1X10WOCKHARDT LIMITED10199.84159.8720
ELTACRO 0.5MG CAP 1X10ELDROGA LIFE SCIENCES PVT LTD10193.5164.4815
SEEGRAF 0.5MG CAP 1X10MICRO LABS LIMITED10193.5116713.7
TACROL 0.5MG CAP 1X10MEDIART LIFE SCIENCES PVT LTD10185.62176.345
IMUNOTAC 0.5MG CAP 1X10RPG LIFE SCIENCES LIMITED10212.5818413.44
TACSURE 0.5MG CAP 1X10MERYNOVA LIFE SCIENCES INDIA PRIVATE LIMITED10216.56184.0815
TACROCORD 0.5MG CAP 1X10CONCORD BIOTECH LTD10216.93184.3915
TACRONIX 0.5MG CAP 1X10MEDGENIX PHARMA INDIA PRIVATE LIMITED10205.31184.7810
VINGRAF 0.5MG CAP 1X10EMCURE PHARMACEUTICALS LIMITED10220.68184.816.26
BIOMUS 0.5MG CAP 1X10ALNICHE LIFE SCIENCES PVT LTD10216.9318614.26
PANGRAF 0.5MG CAP 1X10PANACEA BIOTEC LIMITED10220.68187.5815
TACROLYST 0.5MG CAP 1X10SEPTALYST LIFESCIENCES PVT LTD10216.56194.9110
KEYGRAF 0.5MG CAP 1X10ANTHEM BIOPHARMA1022019810
TACSANT 0.5MG CAP 1X10NOVARTIS INDIA LIMITED10216.93206.085
FUJIGRAF 0.5MG CAP 1X10HOSPIMAX HEALTHCARE PVT LTD10231.3920810.11
PROGRAF 0.5MG CAP 1X10ASTELLAS PHARMA INC10216.93216.930
TACROREN 0.5MG CAP 1X15LA RENON HEALTHCARE PRIVATE LIMITED15329.05279.6915
ADVAGRAF 0.5MG CAP 1X10ASTELLAS PHARMA INC10656.25487.525.71
RENGRAF 0.5MG CAP 1X10ABBOTT HEALTH CARE PRIVATE LIMITED10193.51164.4815
ODVENTA 0.5MG CAP 1X10ZYDUS LIFESCIENCES LIMITED10231.56185.2520
TACROREN 0.5MG CAP 1X10LA RENON HEALTHCARE PRIVATE LIMITED10219.37186.4615
TACROMUS 0.5MG TAB 1X10ZYDUS LIFESCIENCES LIMITED10222.6189.2115
TAKFA 0.5MG CAP 1X10INTAS PHARMACEUTICALS LIMITED10220.7119013.91

FAQs

What if I missed a dose of AMIGRAF 0.5 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with AMIGRAF 0.5 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take AMIGRAF 0.5 CAPSULE 10'S after a transplant?Arrow

The duration of AMIGRAF 0.5 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, AMIGRAF 0.5 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can AMIGRAF 0.5 CAPSULE 10'S increase the risk of infections?Arrow

Yes, AMIGRAF 0.5 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can AMIGRAF 0.5 CAPSULE 10'S affect kidney function?Arrow

AMIGRAF 0.5 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking AMIGRAF 0.5 CAPSULE 10'S?Arrow

AMIGRAF 0.5 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

What are the interactions of AMIGRAF 0.5 CAPSULE 10'S with other drugs?Arrow

There are no known significant interactions of AMIGRAF 0.5 CAPSULE 10'S with other drugs.

What advice should I follow while taking AMIGRAF 0.5 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using AMIGRAF 0.5 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is AMIGRAF 0.5 CAPSULE 10'S made of?Arrow

AMIGRAF 0.5 CAPSULE 10'S is made of TACROLIMUS.

How is AMIGRAF 0.5 CAPSULE 10'S used for Nephrology?Arrow

In Nephrology, AMIGRAF 0.5 CAPSULE 10'S is used to prevent organ rejection in kidney transplant patients.

How is AMIGRAF 0.5 CAPSULE 10'S used for Infectious Diseases?Arrow

In Infectious Diseases, AMIGRAF 0.5 CAPSULE 10'S is used to treat certain autoimmune diseases that may be related to infections.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Book Icon

Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

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Reviewed on 13-06-2023

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Reviewed on 03-04-2022

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Reviewed on 09-07-2023

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Marketer / Manufacturer Details

BIOKINDLE LIFESCIENCES PRIVATE LIMITED

Country of Origin -

India

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