BORTLEE LYOPHILIZED 2MG INJECTION
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BORTLEE LYOPHILIZED 2MG INJECTION

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BORTLEE LYOPHILIZED 2MG INJECTION

By ADMAC LIFESCIENCES

MRP

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5523.52

₹1178

78.67 % OFF

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Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About BORTLEE LYOPHILIZED 2MG INJECTION

  • BORTLEE LYOPHILIZED 2MG INJECTION is a chemotherapy medication classified as a proteasome inhibitor, containing the active ingredient Bortezomib. It is prescribed for treating multiple myeloma, a cancer of plasma cells in the bone marrow, and mantle cell lymphoma, a less common cancer affecting the lymph nodes. This medication is often used alongside other chemotherapy drugs like pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide, especially for patients who are newly diagnosed and not eligible for blood stem cell transplants.
  • BORTLEE LYOPHILIZED 2MG INJECTION works by blocking the action of proteasomes within cells. Proteasomes are responsible for breaking down proteins that regulate cell growth and survival. By inhibiting proteasomes, the injection disrupts these processes, leading to the death of cancerous cells. This targeted approach helps control the spread of cancer and improve patient outcomes.
  • Common side effects associated with BORTLEE LYOPHILIZED 2MG INJECTION include pneumonia, loss of appetite, skin sensitivity, tingling or burning sensations, nausea, vomiting, diarrhea, mouth ulcers, constipation, muscle and bone pain, hair loss, fever, infections, itching, redness, dehydration, and stomach problems. It is crucial to inform your doctor if these side effects become bothersome or persist.
  • Before using BORTLEE LYOPHILIZED 2MG INJECTION, inform your doctor about any allergies to the medication or its components. It should not be used by individuals with severe lung or heart problems. Disclose any pre-existing conditions such as neuropathy (nerve malfunction), cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (low platelet count), neutropenia (low white blood cell count), tumor lysis syndrome (metabolic abnormalities during cancer treatment), or hepatic disorders. Also, inform your doctor if you have diabetes, as this injection may affect blood glucose levels. Regular monitoring and management of these conditions are essential during treatment.

Uses of BORTLEE LYOPHILIZED 2MG INJECTION

  • It is useful in the treatment of multiple myeloma, a type of cancer that affects plasma cells.
  • It also aids in the treatment of mantle cell lymphoma, a type of non-Hodgkin lymphoma.

Side Effects of BORTLEE LYOPHILIZED 2MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Muscle cramps
  • Confusion, visual disturbances, seizures, and headache
  • Breathlessness
  • Swelling of feet
  • Changes in heartbeat
  • High blood pressure
  • Fainting and tiredness
  • Cough and chest tightness
  • Pneumonia
  • Loss of appetite
  • Sensitivity, tingling and burning sensation of the skin
  • Nausea, vomiting, and diarrhea
  • Mouth ulcers
  • Constipation
  • Muscle and bone pain
  • Hair loss
  • Fever
  • Reduction in blood cell count
  • Reduced kidney function
  • Shivering
  • Infections
  • Itching and redness
  • Dehydration
  • Stomach problems
  • Difficulty sleeping, anxiety, mood swings, depressed mood

Safety Advice for BORTLEE LYOPHILIZED 2MG INJECTIONArrow

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Pregnancy

UNSAFE

BORTLEE LYOPHILIZED 2MG INJECTION is unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment.

Dosage of BORTLEE LYOPHILIZED 2MG INJECTIONArrow

  • BORTLEE LYOPHILIZED 2MG INJECTION must be administered intravenously (directly into your vein) or subcutaneously (under the skin). This medication should only be administered by a healthcare professional who is properly trained and experienced in the use of cytotoxic (cell-killing) medications. It is crucial that you do not attempt to self-administer this injection.
  • The healthcare professional administering BORTLEE LYOPHILIZED 2MG INJECTION will determine the appropriate dosage and frequency based on your specific medical condition, weight, and response to treatment. They will also monitor you closely for any potential side effects during and after the injection.
  • The intravenous route allows the medication to enter your bloodstream directly, ensuring rapid distribution throughout your body. Subcutaneous administration involves injecting the medication into the fatty tissue beneath the skin, which allows for slower absorption into the bloodstream. The choice of administration route will be determined by your healthcare provider.
  • It is important to inform your healthcare provider about any other medications you are taking, as well as any allergies or medical conditions you have, before receiving BORTLEE LYOPHILIZED 2MG INJECTION. This will help them to minimize the risk of potential drug interactions or adverse reactions.
  • If you experience any unusual symptoms or discomfort after receiving BORTLEE LYOPHILIZED 2MG INJECTION, such as pain, swelling, redness, or irritation at the injection site, or any signs of an allergic reaction, such as rash, itching, hives, or difficulty breathing, seek immediate medical attention.

How to store BORTLEE LYOPHILIZED 2MG INJECTION?Arrow

  • Keep BORTLEE 2MG INJ away from the reach of children and pets.
  • Store BORTLEE 2MG INJ at room temperature.

Benefits of BORTLEE LYOPHILIZED 2MG INJECTIONArrow

  • BORTLEE LYOPHILIZED 2MG INJECTION is a medication designed to combat cancer by directly targeting and disrupting cancer cell function. It achieves this by exerting a toxic effect, specifically inhibiting the 26S proteasome within cancer cells. This proteasome plays a crucial role in protein degradation, and its inhibition leads to an accumulation of misfolded proteins, ultimately stressing and damaging the cancer cells.
  • Furthermore, BORTLEE LYOPHILIZED 2MG INJECTION interferes with a major cell signaling pathway involved in cancer cell survival and proliferation. By blocking this pathway, the medication effectively makes cancer cells more vulnerable and sensitive to the effects of chemotherapy treatments. This synergistic effect enhances the overall effectiveness of cancer therapy.
  • In addition to proteasome inhibition and signaling pathway interference, BORTLEE LYOPHILIZED 2MG INJECTION promotes the build-up of certain proteins within cancer cells. This accumulation can further disrupt cellular processes essential for growth and division, ultimately minimizing cancer cell growth and multiplication. This multi-faceted approach allows for a more comprehensive attack on cancer cells, improving treatment outcomes.

How to use BORTLEE LYOPHILIZED 2MG INJECTIONArrow

  • BORTLEE LYOPHILIZED 2MG INJECTION is administered intravenously (directly into your vein) or subcutaneously (under the skin). This medication should only be administered by a qualified healthcare professional who is experienced in the safe handling and administration of cytotoxic medications. Cytotoxic medications are drugs that are toxic to cells, and require special precautions during handling and administration.
  • It is crucial to understand that you should never attempt to self-administer this injection. The healthcare professional will carefully calculate the correct dosage based on your individual needs and medical condition. They will also monitor you closely for any potential side effects during and after the injection.
  • The injection process involves careful preparation and sterile techniques to minimize the risk of infection. The healthcare professional will clean the injection site thoroughly before administering the medication. They will also ensure that the injection is given at the correct rate to optimize its effectiveness and minimize discomfort.
  • If you have any questions or concerns about the administration of BORTLEE LYOPHILIZED 2MG INJECTION, please do not hesitate to ask your healthcare provider. They can provide you with more information about the medication, its potential side effects, and the injection process.

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FAQs

What is BORTLEE LYOPHILIZED 2MG INJECTION used for?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION is mainly indicated to treat mantle cell lymphoma and multiple myeloma.

Can I drive while taking BORTLEE LYOPHILIZED 2MG INJECTION?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION may cause dizziness, tiredness, fainting, or blurred vision. Hence, avoid driving and operating heavy machines while this Injection.

How is BORTLEE LYOPHILIZED 2MG INJECTION given?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION is administered intravenously in your vein or subcutaneously under the skin by a doctor in a medical facility.

Is it safe to handle BORTLEE LYOPHILIZED 2MG INJECTION while pregnant?Arrow

No, Pregnant women should not handle BORTLEE LYOPHILIZED 2MG INJECTION as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.

What class of chemo is BORTLEE LYOPHILIZED 2MG INJECTION?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION is a targeted therapy that belongs to the class of medicines called proteasome inhibitors.

Can I take BORTLEE LYOPHILIZED 2MG INJECTION when I am pregnant?Arrow

Avoid taking BORTLEE LYOPHILIZED 2MG INJECTION if you are pregnant, as it can cause harmful effects on the unborn baby. Females should use effective birth control methods during treatment and at least three months after treatment.

I am suffering from a Hepatitis infection. Can I take BORTLEE LYOPHILIZED 2MG INJECTION?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION should not be used in patients with hepatitis infection because they might have a repeated attack of hepatitis, which can be fatal. If you have a history of hepatitis B infection, your doctor will carefully check you for signs of active hepatitis B.

NULL interaction of BORTLEE LYOPHILIZED 2MG INJECTION with other drugsArrow

There is no known interaction of BORTLEE LYOPHILIZED 2MG INJECTION with other drugs.

What advice should be followed during treatment with BORTLEE LYOPHILIZED 2MG INJECTION?Arrow

It is advised that both men and women must use an effective contraception method during treatment and three months afterward. Treatment with BORTLEE LYOPHILIZED 2MG INJECTION can commonly cause a decrease in the number of red and white blood cells and platelets in your blood. Therefore, you will have to take regular blood tests before and during your treatment with bortezomib to check your blood cell counts regularly. Pregnant women should not handle this Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.

What is Bortezomib?Arrow

BORTEZOMIB is molecule/combination used for making BORTLEE LYOPHILIZED 2MG INJECTION.

What type of cancers does BORTLEE LYOPHILIZED 2MG INJECTION treat?Arrow

BORTLEE LYOPHILIZED 2MG INJECTION is mainly indicated to treat ailments related to Oncology such as mantle cell lymphoma and multiple myeloma.

References

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STADA, Electronic Medicines Compendium (EMC)

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Takeda Pharmaceuticals U.S.A.

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Ratings & Review

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Reviewed on 13-06-2023

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Reviewed on 05-02-2024

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Reviewed on 07-01-2024

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(5/5)

Good for generic medicine, quality medicine with affordable rate

nitesh vekariya

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Reviewed on 03-02-2024

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(5/5)


Marketer / Manufacturer Details

ADMAC LIFESCIENCES

Country of Origin -

India

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BORTLEE LYOPHILIZED 2MG INJECTION

MRP

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5523.52

₹1178

78.67 % OFF

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