ZOBISTED 2 INJECTION
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ZOBISTED 2 INJECTION
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ZOBISTED 2 INJECTION

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ZOBISTED 2 INJECTION

By HALSTED PHARMA PVT LTD

MRP

4925.63

₹1500

69.55 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ZOBISTED 2 INJECTION

  • ZOBISTED 2 INJECTION is a chemotherapeutic medication classified as a Proteasome inhibitor, containing the active compound bortezomib. It is prescribed for the treatment of multiple myeloma and mantle cell lymphoma. Often, this medication is used in conjunction with other chemotherapy drugs, such as pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide, particularly for patients who are either newly diagnosed or are not suitable candidates for blood stem cell transplant.
  • Before starting treatment with ZOBISTED 2 INJECTION, it's crucial to inform your doctor about any existing allergies to bortezomib or any other components of the medication. It's also important to disclose if you have a compromised immune system or any active infections, as this medication might not be suitable in such cases. This injection is generally not recommended for children and adolescents, and it should be avoided in patients with hepatitis. Your doctor needs to be aware of any gastrointestinal disorders, liver problems, low platelet count (thrombocytopenia), low white blood cell count (neutropenia), tumor lysis syndrome (a condition involving metabolic abnormalities during cancer treatment), nerve malfunction (neuropathy), heart problems, severe lung issues, pulmonary disorders, or posterior reversible encephalopathy syndrome.
  • During treatment with ZOBISTED 2 INJECTION, regular monitoring of blood counts and liver enzymes is essential. Due to potential harm to the developing fetus, its use during pregnancy and breastfeeding is generally discouraged unless deemed absolutely necessary by the doctor. Women of childbearing age are advised to use effective contraception during treatment and for three months after the last dose. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Additionally, it's vital to provide your doctor with a comprehensive list of all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid any potential interactions.
  • ZOBISTED 2 INJECTION requires careful consideration and open communication with your healthcare provider to ensure safe and effective treatment. Your doctor will determine the appropriate dosage and administration schedule based on your individual needs and medical history. Discuss any concerns or questions you may have regarding the treatment plan.
  • Possible side effects of ZOBISTED 2 INJECTION can include, but are not limited to, nausea, fatigue, peripheral neuropathy (nerve damage), thrombocytopenia (low platelet count), and anemia (low red blood cell count). It's important to promptly report any unusual or bothersome symptoms to your doctor so they can be managed appropriately. Regular monitoring and proactive communication with your healthcare team are crucial for a positive treatment outcome.

Uses of ZOBISTED 2 INJECTION

  • Treatment of multiple myeloma: This medication is used in the treatment of multiple myeloma, a cancer that affects plasma cells. It helps to slow down the progression of the disease and alleviate symptoms.
  • Treatment of mantle cell lymphoma: This medication is indicated for the treatment of mantle cell lymphoma, a type of non-Hodgkin's lymphoma. It aids in reducing the number of cancerous cells and managing the condition effectively.

Side Effects of ZOBISTED 2 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them.

  • Peripheral neuropathy
  • Hypotension
  • Cardiac toxicity
  • Posterior Reversible Encephalopathy Syndrome (PRES)
  • Tumor Lysis Syndrome
  • Hepatic Toxicity
  • Thrombotic Microangiopathy
  • Loss of appetite
  • Sensitivity, tingling and burning sensation of the skin
  • Nausea, vomiting, and diarrhea
  • Mouth ulcers
  • Constipation
  • Muscle and bone pain
  • Hair loss
  • Fever
  • Reduction in blood cell count
  • Reduced kidney function
  • Shivering
  • Infections
  • Dehydration
  • Stomach problems
  • Difficulty sleeping, anxiety, mood swings, depressed mood

Safety Advice for ZOBISTED 2 INJECTIONArrow

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Pregnancy

UNSAFE

ZOBISTED 2 INJECTION should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 3 months after the last dose.

Dosage of ZOBISTED 2 INJECTIONArrow

  • ZOBISTED 2 INJECTION is administered via intravenous injection into your vein or subcutaneously under the skin. This medication is administered exclusively by a healthcare professional within a hospital or clinical setting, ensuring proper administration and monitoring.
  • The specific dosage and frequency of ZOBISTED 2 INJECTION are determined by several factors. These include the patient's age, body weight, overall health status, and the characteristics of the disease being treated, such as its type and stage. Adherence to the healthcare provider's prescribed dosing instructions is crucial for optimal treatment outcomes. Any adjustments to the dosage or frequency should only be made after consulting with the healthcare provider to ensure safety and efficacy.
  • Self-administration of ZOBISTED 2 INJECTION is strictly prohibited. This is to ensure the proper technique is used and to monitor for any immediate adverse reactions that may require medical intervention. Professional administration allows for immediate response to any complications.
  • In the event of a missed dose, it should be administered as soon as it is remembered, provided it is not within 6 hours of the next scheduled dose. If the next dose is less than 6 hours away, the missed dose should be skipped, and the regular dosing schedule should be resumed. It is imperative to avoid taking a double dose of ZOBISTED 2 INJECTION to compensate for a missed dose, as this can lead to potentially harmful side effects. Consult with your healthcare provider for guidance on managing missed doses to maintain consistent therapeutic levels.

How to store ZOBISTED 2 INJECTION?Arrow

  • Keep ZOBISTED 2MG INJ away from the reach of children and pets.
  • Store ZOBISTED 2MG INJ at room temperature.

Benefits of ZOBISTED 2 INJECTIONArrow

  • ZOBISTED 2 INJECTION is designed to target and eliminate cancer cells through a multifaceted approach. It works by directly interfering with the internal mechanisms of these cells, specifically by exerting a toxic effect that leads to their destruction. The drug's primary mechanism involves inhibiting the 26S proteasome, a crucial component responsible for protein degradation within the cell. By blocking this proteasome, ZOBISTED 2 INJECTION disrupts the normal process of protein recycling, causing a buildup of misfolded and damaged proteins. This accumulation creates a stressful environment within the cancer cell, ultimately leading to its demise.
  • Furthermore, ZOBISTED 2 INJECTION interferes with a major cell signaling pathway, effectively blocking critical communication channels that cancer cells rely on for survival and proliferation. This disruption makes the cancer cells more vulnerable and sensitive to the effects of chemotherapy. In essence, ZOBISTED 2 INJECTION weakens the cancer cells' defenses, paving the way for other treatments to be more effective. The accumulation of these misfolded proteins then triggers a cascade of cellular responses, activating stress pathways and inducing apoptosis, or programmed cell death. This dual action of disrupting protein degradation and blocking cell signaling enhances the buildup of specific proteins, which further minimizes cancer cell growth and multiplication, contributing to the overall effectiveness of the treatment.
  • In simpler terms, ZOBISTED 2 INJECTION essentially poisons cancer cells by preventing them from properly disposing of their waste and disrupting their ability to communicate and multiply. This makes them weaker and more susceptible to other cancer treatments, ultimately helping to slow down or stop the growth of the disease.

How to use ZOBISTED 2 INJECTIONArrow

  • ZOBISTED 2 INJECTION is administered intravenously (into your vein) or subcutaneously (under the skin) via injection. It's crucial to understand that this medication should only be administered by a qualified healthcare professional in a hospital or clinical setting. Attempting to self-administer this injection can lead to serious complications and should be strictly avoided.
  • The precise dosage and frequency of ZOBISTED 2 INJECTION administration are determined by a healthcare provider, taking into account several individual factors. These include your age, weight, overall health status, and the specific type and stage of the disease being treated. It is of utmost importance to adhere strictly to the dosing instructions provided by your healthcare provider. Do not, under any circumstances, alter the dosage or frequency of injections without first consulting with your doctor or other qualified medical professional.
  • If you happen to miss a scheduled dose of ZOBISTED 2 INJECTION, take it as soon as you remember, provided it is not within 6 hours of your next scheduled dose. If it is within 6 hours, skip the missed dose entirely and resume your regular dosing schedule. Never take a double dose of ZOBISTED 2 INJECTION to compensate for a missed dose, as this can lead to dangerous side effects. It is important to maintain a consistent schedule as prescribed by your healthcare provider for optimal results. Consistent and correct administration ensures the medication works as intended, maximizing its benefits and minimizing potential risks.
  • During the course of your treatment with ZOBISTED 2 INJECTION, regular monitoring by your healthcare provider is essential. This allows them to assess your response to the medication and make any necessary adjustments to your treatment plan. Be sure to attend all scheduled appointments and promptly report any side effects or concerns you may experience. Effective communication with your healthcare team is vital for a successful treatment outcome.

FAQs

I have an infection with hepatitis. Is ZOBISTED 2 INJECTION safe to take?Arrow

Patients with active hepatitis should not take ZOBISTED 2 INJECTION. Because they may experience recurrent, potentially fatal cases of hepatitis. Your doctor will closely monitor you for signs of active hepatitis B if you have a history of the infection.

How long can I take ZOBISTED 2 INJECTION?Arrow

The duration of ZOBISTED 2 INJECTION treatment can vary depending on the individual's condition and response to the medication. In some cases, this medicine may be used as a long-term maintenance therapy, while treatment duration may be shorter in other situations. It is important to follow the healthcare provider's guidance regarding the appropriate duration of treatment.

What parameters will be monitored during treatment with ZOBISTED 2 INJECTION?Arrow

During treatment with ZOBISTED 2 INJECTION, your health care provider will monitor RBC, WBC, platelets, liver, blood glucose and kidney parameters.

NULL interaction of ZOBISTED 2 INJECTION with other drungsArrow

There is no known interaction of ZOBISTED 2 INJECTION with other drugs.

What advice should I follow while taking ZOBISTED 2 INJECTION?Arrow

If you have been prescribed ZOBISTED 2 INJECTION, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping ZOBISTED 2 INJECTION. It is advised that both men and women must use an effective contraception method during treatment and three months afterward. Treatment with ZOBISTED 2 INJECTION can commonly cause a decrease in the number of red and white blood cells and platelets in your blood. Therefore, you will have to take regular blood tests before and during your treatment with ZOBISTED 2 INJECTION to check your blood cell counts regularly. Include anti-inflammatory foods in your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish. Include foods like avocados, almonds, seeds, and olive oil in your diet as sources of healthful fats. These fats can improve general health by lowering inflammation. To stay hydrated, sip lots of water throughout the day. Monitor your blood sugar level frequently If you are taking antidiabetic medication and report to your physician if you notice any fluctuations in your blood sugar levels. Consult your physician before getting any vaccinations because certain of them can make you sick and should not be administered while you are on this medication. If you currently have or have ever had hepatitis B, let your doctor know. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.

What is Bortezomib and how does it help in making ZOBISTED 2 INJECTION?Arrow

Bortezomib is a molecule used for making ZOBISTED 2 INJECTION.

For which ailments/diseases/conditions ZOBISTED 2 INJECTION is prescribed?Arrow

ZOBISTED 2 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

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Tillomed Laboratories Ltd, Electronics Medicines Compendium(emc)

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MAIA Pharmaceuticals, Inc,  United States Food and Drug Administration (US FDA)

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Pfizer

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Dr. Reddy’s Laboratories Limited

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Reviewed on 02-02-2024

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Marketer / Manufacturer Details

HALSTED PHARMA PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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