GOLDMET TRIO 2MG TABLET 10'S
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GOLDMET TRIO 2MG TABLET 10'SGOLDMET TRIO 2MG TABLET 10'SGOLDMET TRIO 2MG TABLET 10'S
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GOLDMET TRIO 2MG TABLET 10'S

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GOLDMET TRIO 2MG TABLET 10'S

By UNIZA HEALTHCARE LLP

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172.6

₹146.71

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About GOLDMET TRIO 2MG TABLET 10'S

  • GOLDMET TRIO 2MG TABLET 10'S is a combination medicine meticulously formulated to address type 2 diabetes mellitus. It synergistically combines three active ingredients – Glimepiride, Metformin, and Pioglitazone – each playing a vital role in managing blood sugar levels. This powerful trio works through different mechanisms to provide comprehensive glycemic control, helping patients achieve and maintain optimal health.
  • Glimepiride belongs to the class of drugs known as sulfonylureas. It functions by stimulating the pancreas to release more insulin. Insulin is a crucial hormone that enables glucose (sugar) to move from the blood into cells, where it is used for energy. By increasing insulin secretion, Glimepiride helps lower blood sugar levels, particularly after meals.
  • Metformin, a biguanide, operates primarily by reducing glucose production in the liver. It also enhances insulin sensitivity, allowing the body to use insulin more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines, further contributing to lower blood sugar levels. It is often the first-line treatment for type 2 diabetes due to its effectiveness and generally well-tolerated nature.
  • Pioglitazone is a thiazolidinedione that improves insulin sensitivity in muscle and fat tissues. By making these tissues more responsive to insulin, Pioglitazone allows glucose to be utilized more efficiently, thereby lowering blood sugar levels. It also helps to reduce glucose production in the liver.
  • GOLDMET TRIO 2MG TABLET 10'S is typically prescribed when diet and exercise alone are insufficient to control blood sugar levels in patients with type 2 diabetes. It is crucial to take this medication as directed by your healthcare provider, usually once or twice daily with meals. Regular monitoring of blood sugar levels is essential to ensure the medication is working effectively and to adjust the dosage as needed.
  • Before starting GOLDMET TRIO 2MG TABLET 10'S, inform your doctor about any pre-existing medical conditions, especially kidney or liver disease, heart problems, or any allergies. Potential side effects may include hypoglycemia (low blood sugar), nausea, diarrhea, and weight gain. It is important to be aware of the symptoms of hypoglycemia, such as sweating, shaking, rapid heartbeat, and confusion, and to have a readily available source of sugar, like glucose tablets or juice.
  • This medication should be used with caution in elderly patients and is generally not recommended for patients with type 1 diabetes or diabetic ketoacidosis. Always consult your healthcare provider for personalized advice and to determine if GOLDMET TRIO 2MG TABLET 10'S is the right choice for you. Remember, managing diabetes effectively requires a holistic approach that includes medication, a healthy diet, regular exercise, and consistent monitoring of blood sugar levels.

Uses of GOLDMET TRIO 2MG TABLET 10'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance associated with polycystic ovary syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (in some patients)

How GOLDMET TRIO 2MG TABLET 10'S Works

  • GOLDMET TRIO 2MG TABLET 10'S is a combination medication designed to manage type 2 diabetes mellitus. It combines the power of three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to achieve optimal blood sugar control. This multi-pronged approach addresses various aspects of diabetes, making it an effective treatment option for many individuals.
  • Glimepiride, a sulfonylurea, primarily stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells, where it's used for energy. By increasing insulin secretion, glimepiride effectively lowers blood glucose levels, particularly after meals. It essentially acts as a key that unlocks the door for glucose to enter the cells.
  • Metformin, a biguanide, works in several ways to reduce blood sugar. First, it decreases the amount of glucose produced by the liver. The liver is a major source of glucose, especially when you haven't eaten for a while. Metformin helps to suppress this glucose production, preventing excessive blood sugar spikes. Second, metformin improves the body's sensitivity to insulin. This means that the insulin that is already present in the body works more effectively, allowing more glucose to enter the cells. Third, metformin slows down the absorption of glucose from the intestines into the bloodstream after a meal. This helps to prevent a rapid rise in blood sugar levels.
  • Pioglitazone, a thiazolidinedione (TZD), primarily enhances insulin sensitivity in peripheral tissues such as muscle and fat. It works by activating a receptor called PPARγ (peroxisome proliferator-activated receptor gamma), which regulates genes involved in glucose and lipid metabolism. By improving insulin sensitivity, pioglitazone allows the body to use insulin more efficiently, lowering blood sugar levels. It also helps to reduce insulin resistance, a common problem in type 2 diabetes.
  • In summary, GOLDMET TRIO 2MG TABLET 10'S works by a triple action mechanism: glimepiride stimulates insulin release, metformin reduces glucose production by the liver and improves insulin sensitivity, and pioglitazone further enhances insulin sensitivity in peripheral tissues. This synergistic effect helps to effectively lower blood sugar levels and improve overall glycemic control in individuals with type 2 diabetes. It is crucial to take this medication as prescribed by your doctor and to follow a healthy diet and exercise plan to maximize its benefits.

Side Effects of GOLDMET TRIO 2MG TABLET 10'SArrow

The most common side effects of GOLDMET TRIO 2MG TABLET 10'S are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects include: * Headache * Dizziness * Weakness * Fatigue * Constipation * Skin rash * Itching * Upper respiratory tract infection * Weight gain * Edema (swelling) * Lactic acidosis (rare but serious). Symptoms may include feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, especially in your arms and legs, feeling dizzy or lightheaded, and a slow or irregular heartbeat. * Vitamin B12 deficiency: Symptoms may include fatigue, weakness, constipation, loss of appetite, weight loss, and nerve problems such as numbness and tingling in the hands and feet. * Liver problems: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, light-colored stools, and abdominal pain. This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any troublesome side effects.

Safety Advice for GOLDMET TRIO 2MG TABLET 10'SArrow

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Allergies

Consult a Doctor

Consult your doctor if you have any allergies with GOLDMET TRIO 2MG TABLET 10'S.

Dosage of GOLDMET TRIO 2MG TABLET 10'SArrow

  • The recommended dosage of GOLDMET TRIO 2MG TABLET 10'S varies depending on individual patient needs and should be determined by a qualified healthcare professional. Typically, the starting dose is one tablet daily, taken orally. Your doctor will adjust the dosage based on your blood glucose levels and individual response to the medication. It is crucial to adhere strictly to the prescribed dosage and timing to achieve optimal glycemic control.
  • GOLDMET TRIO 2MG TABLET 10'S should be taken with meals to minimize the risk of gastrointestinal side effects. Consistent timing of administration is vital for maintaining stable blood glucose levels throughout the day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Never double the dose to compensate for a missed one.
  • Regular monitoring of blood glucose levels is essential while taking GOLDMET TRIO 2MG TABLET 10'S to assess its effectiveness and adjust the dosage accordingly. Inform your doctor about any other medications you are taking, as drug interactions can affect the efficacy and safety of GOLDMET TRIO 2MG TABLET 10'S. It's important to follow your doctor's instructions regarding diet and exercise while taking this medication to help manage your diabetes effectively. The maximum daily dosage should not exceed what your doctor prescribes.
  • Take 'GOLDMET TRIO 2MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of GOLDMET TRIO 2MG TABLET 10'S?Arrow

  • If you miss a dose of GOLDMET TRIO 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GOLDMET TRIO 2MG TABLET 10'S?Arrow

  • Keep GOLDMET TRIO 2MG TAB 1X10 away from the reach of children and pets.
  • Store GOLDMET TRIO 2MG TAB 1X10 at room temperature.

Benefits of GOLDMET TRIO 2MG TABLET 10'SArrow

  • GOLDMET TRIO 2MG TABLET 10'S is a combination medication primarily used to manage type 2 diabetes mellitus. It contains three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to effectively control blood sugar levels. This triple combination offers a comprehensive approach to glycemic control, making it beneficial for individuals who haven't achieved their target blood sugar levels with single or dual therapy.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is crucial for allowing glucose to enter cells from the bloodstream, thereby lowering blood sugar levels. By increasing insulin secretion, glimepiride helps to reduce hyperglycemia, particularly after meals. This component is particularly effective in managing postprandial (after-meal) blood sugar spikes.
  • Metformin, a biguanide, works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. It reduces the amount of glucose released into the bloodstream by the liver and enhances the uptake and utilization of glucose by muscles and other tissues. Metformin is also known to have a mild appetite-suppressing effect and may contribute to modest weight loss in some individuals, which is an added benefit for many patients with type 2 diabetes who are often overweight or obese.
  • Pioglitazone, a thiazolidinedione (TZD), enhances insulin sensitivity in peripheral tissues such as muscle and fat. It works by activating PPARγ receptors, which play a key role in glucose and lipid metabolism. By improving insulin sensitivity, pioglitazone helps the body use insulin more effectively, thereby lowering blood sugar levels. Additionally, pioglitazone can have beneficial effects on lipid profiles, potentially reducing triglyceride levels and increasing HDL (good) cholesterol.
  • The combined action of these three medications provides several advantages. Firstly, it addresses multiple aspects of type 2 diabetes, including insulin secretion, insulin sensitivity, and hepatic glucose production. This multi-pronged approach can lead to better overall glycemic control compared to using a single medication. Secondly, it simplifies the treatment regimen for patients who would otherwise need to take multiple pills to achieve the same level of control. A single tablet containing all three medications improves adherence and convenience.
  • GOLDMET TRIO 2MG TABLET 10'S helps in reducing the risk of long-term complications associated with poorly controlled diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). By maintaining stable blood sugar levels, this medication can significantly improve the overall health and quality of life for individuals with type 2 diabetes.
  • It is important to note that GOLDMET TRIO 2MG TABLET 10'S should be used as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and exercise. Regular monitoring of blood sugar levels and adherence to the prescribed dosage are essential for optimal results. Patients should also be aware of potential side effects and discuss any concerns with their healthcare provider.

How to use GOLDMET TRIO 2MG TABLET 10'SArrow

  • GOLDMET TRIO 2MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It contains three active ingredients that work together to control blood sugar levels. To get the most benefit from this medication, it's crucial to follow your doctor's instructions carefully and adhere to the recommended dosage and timing.
  • Typically, GOLDMET TRIO 2MG TABLET 10'S is taken orally, usually once or twice daily, with meals. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your body. Taking it with food helps to reduce the likelihood of stomach upset and aids in better absorption of the medication.
  • Consistency is key when taking this medication. Try to take it at the same time(s) each day to help you remember. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It's essential to maintain a healthy lifestyle while taking GOLDMET TRIO 2MG TABLET 10'S. This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle modifications can significantly improve blood sugar control and overall health. Limit your intake of sugary foods and drinks, and focus on consuming whole grains, lean proteins, and plenty of fruits and vegetables.
  • Regular monitoring of your blood sugar levels is also crucial while taking this medication. Your doctor may advise you to check your blood sugar at home using a glucose meter. Keep a record of your blood sugar readings and share them with your doctor during your check-ups. This will help your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting GOLDMET TRIO 2MG TABLET 10'S. Certain medications can interact with this medicine and affect its effectiveness or increase the risk of side effects. Also, notify your doctor if you have any kidney or liver problems, heart conditions, or other underlying health issues.
  • Be aware of potential side effects, such as nausea, diarrhea, or stomach upset. If these side effects persist or become bothersome, consult your doctor. In rare cases, GOLDMET TRIO 2MG TABLET 10'S can cause more serious side effects, such as lactic acidosis. Seek immediate medical attention if you experience symptoms like muscle pain, weakness, difficulty breathing, or persistent stomach pain.
  • GOLDMET TRIO 2MG TABLET 10'S is meant to be used as part of a comprehensive diabetes management plan. Work closely with your doctor and other healthcare professionals to develop a personalized plan that meets your individual needs. This may include dietary changes, exercise recommendations, and other medications.

Quick Tips for GOLDMET TRIO 2MG TABLET 10'SArrow

  • Take GOLDMET TRIO 2MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this medication is designed to manage your blood sugar levels effectively. Consistency is key for optimal results.
  • GOLDMET TRIO 2MG TABLET 10'S is usually taken with meals to minimize gastrointestinal side effects. Try to take it at the same time(s) each day to help you remember and maintain a steady level of medication in your bloodstream. Food helps in better absorbtion of the medicine.
  • While taking GOLDMET TRIO 2MG TABLET 10'S, it's crucial to monitor your blood sugar levels regularly, especially in the beginning. Keep a log of your readings and share them with your healthcare provider. This will help them adjust your dosage if needed and ensure that the medication is working effectively for you. Inform doctor about any other medication you are taking.
  • GOLDMET TRIO 2MG TABLET 10'S works best when combined with a healthy lifestyle. Focus on eating a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle modifications can significantly improve your blood sugar control and overall health. Avoid eating junk food and fried items.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, rapid heartbeat, and confusion. Always carry a source of fast-acting sugar, like glucose tablets or fruit juice, in case your blood sugar drops too low. If you experience any severe or persistent side effects, consult your doctor immediately. Don't ignore the symptoms of low or high sugar.

Food Interactions with GOLDMET TRIO 2MG TABLET 10'SArrow

  • GOLDMET TRIO 2MG TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day to maintain consistent blood sugar levels.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of side effects such as low blood sugar (hypoglycemia).
  • Inform your doctor if you are on any specific diet plan, as it might require adjustments in your medication dosage.

FAQs

What is GOLDMET TRIO 2MG TABLET 10'S?Arrow

GOLDMET TRIO 2MG TABLET 10'S is a combination of three medicines used to lower high blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise are not enough to control blood sugar levels.

How does GOLDMET TRIO 2MG TABLET 10'S work?Arrow

GOLDMET TRIO 2MG TABLET 10'S contains three medicines: Metformin, Glimepiride and Pioglitazone. Metformin works by decreasing glucose production in the liver and improving insulin sensitivity. Glimepiride works by increasing the amount of insulin released by the pancreas. Pioglitazone works by increasing insulin sensitivity.

What are the common side effects of GOLDMET TRIO 2MG TABLET 10'S?Arrow

Common side effects of GOLDMET TRIO 2MG TABLET 10'S include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is GOLDMET TRIO 2MG TABLET 10'S safe for the kidneys?Arrow

GOLDMET TRIO 2MG TABLET 10'S should be used with caution in patients with kidney disease. Dosage adjustment may be needed. Please consult your doctor.

Is GOLDMET TRIO 2MG TABLET 10'S safe during pregnancy?Arrow

GOLDMET TRIO 2MG TABLET 10'S is not recommended during pregnancy. Inform your doctor if you are pregnant or planning to become pregnant.

Is GOLDMET TRIO 2MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether GOLDMET TRIO 2MG TABLET 10'S passes into breast milk. Consult your doctor before using it while breastfeeding.

Is GOLDMET TRIO 2MG TABLET 10'S safe with alcohol?Arrow

It is not recommended to consume GOLDMET TRIO 2MG TABLET 10'S with alcohol as it can lower blood sugar levels.

What is the dosage of GOLDMET TRIO 2MG TABLET 10'S?Arrow

The dosage of GOLDMET TRIO 2MG TABLET 10'S will be determined by your doctor. The dosage will be based on your medical condition and response to treatment.

How to store GOLDMET TRIO 2MG TABLET 10'S?Arrow

Store GOLDMET TRIO 2MG TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Does GOLDMET TRIO 2MG TABLET 10'S cause weight gain?Arrow

Yes, GOLDMET TRIO 2MG TABLET 10'S can cause weight gain in some patients. It is important to maintain a healthy diet and regular exercise.

What happens if I miss a dose of GOLDMET TRIO 2MG TABLET 10'S?Arrow

If you miss a dose of GOLDMET TRIO 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Does GOLDMET TRIO 2MG TABLET 10'S interact with other medications?Arrow

Yes, GOLDMET TRIO 2MG TABLET 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including over-the-counter medicines, vitamins, and herbal supplements.

Can GOLDMET TRIO 2MG TABLET 10'S be taken on an empty stomach?Arrow

It is best to take GOLDMET TRIO 2MG TABLET 10'S with food. This helps to reduce the chance of stomach upset.

What are the symptoms of an overdose of GOLDMET TRIO 2MG TABLET 10'S?Arrow

Symptoms of an overdose of GOLDMET TRIO 2MG TABLET 10'S may include hypoglycemia (low blood sugar), nausea, vomiting, abdominal pain, and lactic acidosis.

Can I take other medications for diabetes along with GOLDMET TRIO 2MG TABLET 10'S?Arrow

Consult your doctor before taking any other medications, especially for diabetes. Some medications can interact with GOLDMET TRIO 2MG TABLET 10'S.

References

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FDA Label for Metformin Hydrochloride, Glimepiride, and Pioglitazone Hydrochloride Tablets. This document provides detailed information on the drug's composition, indications, dosage, contraindications, warnings, precautions, adverse reactions, and clinical pharmacology.

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DrugBank entry for Glimepiride. This provides chemical information, pharmacology, pharmacokinetics, and interactions for Glimepiride, one of the active ingredients in Goldmet Trio.

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DrugBank entry for Metformin. This provides chemical information, pharmacology, pharmacokinetics, and interactions for Metformin, one of the active ingredients in Goldmet Trio.

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DrugBank entry for Pioglitazone. This provides chemical information, pharmacology, pharmacokinetics, and interactions for Pioglitazone, one of the active ingredients in Goldmet Trio.

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PubMed Central. A free archive of biomedical and life sciences literature. Search for articles on Metformin, Glimepiride, or Pioglitazone to find research related to their use and effects.

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European Medicines Agency. Search for scientific guidelines and assessment reports related to Metformin, Glimepiride, or Pioglitazone.

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UpToDate. A subscription-based resource that provides comprehensive clinical information. Search for information on Metformin, Glimepiride, and Pioglitazone, including their mechanisms of action, clinical uses, and potential side effects. (Subscription Required)

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American Heart Association Journals. Research on cardiovascular effects and considerations for drugs like Metformin, Glimepiride, and Pioglitazone.

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American Diabetes Association. Guidelines and research related to diabetes management, including the use of Metformin, Glimepiride, and Pioglitazone.

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