TRIVOGLITOR 2MG TABLET 10'S
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TRIVOGLITOR 2MG TABLET 10'STRIVOGLITOR 2MG TABLET 10'STRIVOGLITOR 2MG TABLET 10'S
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TRIVOGLITOR 2MG TABLET 10'S

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TRIVOGLITOR 2MG TABLET 10'S

By TORRENT PHARMACEUTICALS LIMITED

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280

₹238

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About TRIVOGLITOR 2MG TABLET 10'S

  • TRIVOGLITOR 2MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls high blood sugar levels by enhancing insulin sensitivity and reducing glucose production in the liver. This medication is typically prescribed when diet and exercise alone are insufficient to manage blood sugar levels.
  • The tablet contains a combination of three active ingredients: Voglibose, Pioglitazone, and Metformin. Voglibose is an alpha-glucosidase inhibitor that slows down the absorption of carbohydrates from the intestine, preventing rapid spikes in blood sugar after meals. Pioglitazone is a thiazolidinedione that improves insulin sensitivity in peripheral tissues, allowing cells to utilize glucose more effectively. Metformin is a biguanide that decreases glucose production in the liver and enhances insulin sensitivity.
  • TRIVOGLITOR 2MG TABLET is usually taken orally with food to minimize gastrointestinal side effects. The dosage is determined by a doctor based on individual blood sugar levels, response to treatment, and other medications being taken. It's essential to follow the doctor's instructions carefully and to monitor blood sugar levels regularly while taking this medicine. Regular exercise, a healthy diet, and weight management are also crucial for managing type 2 diabetes effectively.
  • Common side effects of TRIVOGLITOR 2MG TABLET may include nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). Hypoglycemia can occur if the medication is taken with other diabetes medications or if meals are skipped. It's important to be aware of the symptoms of hypoglycemia (such as shakiness, sweating, and confusion) and to carry a source of fast-acting glucose, like glucose tablets or juice, to treat it promptly. It's also important to inform your doctor about any other medical conditions or medications being taken before starting TRIVOGLITOR 2MG TABLET.

Uses of TRIVOGLITOR 2MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)

How TRIVOGLITOR 2MG TABLET 10'S Works

  • TRIVOGLITOR 2MG TABLET is a combination medication designed to manage type 2 diabetes mellitus. It combines three active ingredients, each working through a different mechanism to achieve comprehensive glycemic control.
  • **Pioglitazone:** This component belongs to the thiazolidinedione class of drugs. Pioglitazone primarily acts as an insulin sensitizer. It improves the body's response to insulin by targeting the peroxisome proliferator-activated receptor gamma (PPARγ). PPARγ receptors are mainly found in adipose tissue, but also present in other tissues including muscle and liver. When pioglitazone activates PPARγ, it leads to several beneficial effects:
  • * Increased glucose uptake and utilization in peripheral tissues (like muscles): This helps lower blood glucose levels by allowing cells to take up glucose more effectively.
  • * Reduced hepatic glucose production: The liver is a major source of glucose, and pioglitazone reduces the liver's output of glucose, further contributing to lower blood sugar levels.
  • * Improved insulin sensitivity in adipose tissue: This helps to regulate fat metabolism and reduces insulin resistance.
  • **Voglibose:** Voglibose is an alpha-glucosidase inhibitor. It works in the small intestine to delay the absorption of carbohydrates. Here's how:
  • * Alpha-glucosidase enzymes are responsible for breaking down complex carbohydrates into simpler sugars (like glucose) that can be absorbed into the bloodstream.
  • * Voglibose inhibits these enzymes, slowing down the digestion and absorption of carbohydrates. This results in a blunting of the postprandial (after-meal) rise in blood glucose levels.
  • **Glibenclamide:** This ingredient is a sulfonylurea. Sulfonylureas stimulate the pancreas to release more insulin. Specifically:
  • * Glibenclamide binds to specific receptors on pancreatic beta cells. This binding stimulates the release of insulin, regardless of the blood glucose level. Therefore, it is important to monitor blood glucose levels carefully to avoid hypoglycemia (low blood sugar).
  • In summary, TRIVOGLITOR 2MG TABLET utilizes a three-pronged approach to manage blood sugar:
  • * Pioglitazone enhances insulin sensitivity.
  • * Voglibose slows down carbohydrate absorption.
  • * Glibenclamide stimulates insulin secretion.
  • This combination helps to improve glycemic control in patients with type 2 diabetes by addressing different aspects of the disease, leading to better overall blood sugar management. It's crucial to take this medication as prescribed by your doctor and to adhere to dietary and exercise recommendations for optimal results. Regular monitoring of blood glucose levels is also essential to ensure the medication is working effectively and to prevent potential side effects.

Side Effects of TRIVOGLITOR 2MG TABLET 10'SArrow

Common side effects of TRIVOGLITOR 2MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, and edema (swelling). Uncommon side effects may include liver problems, allergic reactions (rash, itching, swelling), anemia, and lactic acidosis (rare but serious). Other reported side effects include weight gain, blurred vision, and increased risk of bone fractures in women.

Safety Advice for TRIVOGLITOR 2MG TABLET 10'SArrow

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Allergies

Allergies

Do not use TRIVOGLITOR 2MG TABLET 10'S if you are allergic to it.

Dosage of TRIVOGLITOR 2MG TABLET 10'SArrow

  • The recommended dosage of TRIVOGLITOR 2MG TABLET 10'S varies depending on individual patient needs, blood glucose levels, and response to treatment. It is crucial to adhere strictly to your physician's instructions regarding dosage and timing. Typically, the starting dose is low and gradually increased to achieve optimal glycemic control. The usual starting dose is often 1mg once daily, taken with or without food.
  • Your doctor may adjust the dosage of TRIVOGLITOR 2MG TABLET 10'S based on your blood glucose readings and HbA1c levels. Dosage adjustments are typically made in increments, with sufficient time allowed to assess the response. The maximum recommended daily dose should not be exceeded. It’s important to maintain a consistent schedule for taking TRIVOGLITOR 2MG TABLET 10'S to ensure stable blood sugar levels throughout the day.
  • If you miss a dose of TRIVOGLITOR 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Always consult your doctor or pharmacist if you have any questions about your dosage or how to manage missed doses. Regular monitoring of blood glucose levels is essential while taking this medication to ensure its effectiveness and to adjust the dosage accordingly.
  • Take 'TRIVOGLITOR 2MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of TRIVOGLITOR 2MG TABLET 10'S?Arrow

  • If you miss a dose of TRIVOGLITOR 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store TRIVOGLITOR 2MG TABLET 10'S?Arrow

  • Keep TRIVOGLITOR 2MG TAB 1X10 away from the reach of children and pets.
  • Store TRIVOGLITOR 2MG TAB 1X10 at room temperature.

Benefits of TRIVOGLITOR 2MG TABLET 10'SArrow

  • TRIVOGLITOR 2MG TABLET 10'S is a combination medicine used to effectively manage type 2 diabetes mellitus, particularly in patients whose blood sugar levels are not adequately controlled by diet, exercise, and other anti-diabetic medications alone. This triple combination offers a synergistic approach to lower blood glucose by targeting different mechanisms involved in glucose regulation.
  • One of the primary benefits of TRIVOGLITOR is its ability to improve insulin sensitivity. Pioglitazone, one of the active ingredients, belongs to the thiazolidinedione class of drugs, which work by making the body's cells more responsive to insulin. This allows insulin to more effectively transport glucose from the bloodstream into cells for energy, thereby lowering blood sugar levels.
  • Another key benefit is the reduction of glucose production by the liver. Metformin, a biguanide, acts primarily by decreasing the amount of glucose produced by the liver and also improves insulin sensitivity. This dual action helps to control fasting blood sugar levels and prevent excessive glucose release into the bloodstream.
  • TRIVOGLITOR also helps in delaying the absorption of glucose from the intestines. Voglibose, an alpha-glucosidase inhibitor, works by inhibiting enzymes in the small intestine that break down complex carbohydrates into glucose. This slows down the absorption of glucose into the bloodstream after meals, preventing sharp spikes in blood sugar levels, which is particularly beneficial for postprandial hyperglycemia.
  • By combining these three medications, TRIVOGLITOR provides comprehensive glycemic control. It effectively lowers both fasting and postprandial blood sugar levels, leading to better overall blood sugar management. This comprehensive control can help reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • TRIVOGLITOR's ability to improve insulin sensitivity can also have positive effects on other metabolic parameters. It may help improve lipid profiles, reduce inflammation, and lower blood pressure, all of which contribute to a reduced risk of cardiovascular events in diabetic patients.
  • The convenience of taking a single tablet containing three different medications can improve adherence to treatment. Simplified regimens can lead to better compliance and, consequently, improved health outcomes for individuals managing type 2 diabetes.
  • TRIVOGLITOR assists in weight management. Pioglitazone, while it can cause some weight gain in some individuals, can also help redistribute fat in a more favorable manner, potentially reducing visceral fat. Metformin is often associated with modest weight loss or weight stabilization, which can be beneficial for overweight or obese individuals with type 2 diabetes.
  • TRIVOGLITOR, through its multifaceted mechanism of action, not only manages blood sugar levels but also addresses several underlying metabolic issues associated with type 2 diabetes, offering a holistic approach to diabetes care and potentially improving the overall quality of life for patients.

How to use TRIVOGLITOR 2MG TABLET 10'SArrow

  • TRIVOGLITOR 2MG TABLET 10'S is an oral anti-diabetic medication used to manage blood sugar levels in individuals with type 2 diabetes. It is typically prescribed when diet and exercise alone are not sufficient to control hyperglycemia. To maximize the effectiveness and minimize potential side effects of TRIVOGLITOR, it's important to adhere to your doctor's instructions meticulously.
  • The usual starting dosage of TRIVOGLITOR is determined by your doctor, taking into account your blood glucose levels, HbA1c (a measure of long-term blood sugar control), and any other medications you may be taking. It is commonly taken once or twice daily, with or without food. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it.
  • Consistency is crucial. Take TRIVOGLITOR at the same time(s) each day to help you remember. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • TRIVOGLITOR works best when combined with a healthy lifestyle. Continue to follow your prescribed diet and exercise plan while taking this medication. Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan.
  • Be aware of the possible side effects of TRIVOGLITOR. Common side effects include hypoglycemia (low blood sugar), nausea, diarrhea, and abdominal pain. If you experience any severe or persistent side effects, such as allergic reactions (rash, itching, swelling), liver problems (yellowing of the skin or eyes, dark urine), or unexplained weight gain, seek immediate medical attention.
  • Before starting TRIVOGLITOR, inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications can interact with TRIVOGLITOR, affecting its effectiveness or increasing the risk of side effects. Also, disclose any pre-existing medical conditions you may have, especially kidney or liver disease, heart problems, or any history of allergic reactions.
  • Store TRIVOGLITOR at room temperature, away from heat, moisture, and direct sunlight. Keep it out of the reach of children and pets. Always follow your doctor's instructions and attend regular check-ups to monitor your progress and address any concerns you may have.

Quick Tips for TRIVOGLITOR 2MG TABLET 10'SArrow

  • Take TRIVOGLITOR 2MG TABLET 10'S as prescribed by your doctor. It's usually taken once daily, but the dosage and timing can vary depending on your individual needs and other medications you might be taking. Always follow your doctor's instructions carefully to achieve the best results in managing your blood sugar levels.
  • To maximize the effectiveness of TRIVOGLITOR 2MG TABLET 10'S, take it with your first main meal of the day. This helps to control the rise in blood sugar that naturally occurs after eating. Consistency is key, so try to take it at the same time each day to establish a routine.
  • TRIVOGLITOR 2MG TABLET 10'S works best when combined with a healthy lifestyle. This includes a balanced diet, regular physical activity, and maintaining a healthy weight. Focus on incorporating more fruits, vegetables, and whole grains into your diet, and aim for at least 30 minutes of moderate-intensity exercise most days of the week. Consult with a dietician or healthcare professional for personalized guidance.
  • Be aware of the potential side effects of TRIVOGLITOR 2MG TABLET 10'S. The most common side effects include hypoglycemia (low blood sugar), gastrointestinal discomfort (such as nausea or diarrhea), and headache. If you experience any severe or persistent side effects, contact your doctor immediately. Carry a source of fast-acting sugar (like glucose tablets or juice) with you in case of hypoglycemia.
  • Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your healthcare provider assess how well TRIVOGLITOR 2MG TABLET 10'S is working and make any necessary adjustments to your treatment plan. Keep a record of your blood sugar readings and share them with your doctor during your appointments. Also, inform your doctor about any other medications or supplements you are taking to avoid potential drug interactions.

Food Interactions with TRIVOGLITOR 2MG TABLET 10'SArrow

  • TRIVOGLITOR 2MG TABLET 10'S should be taken as directed by your doctor. Typically, it is recommended to take this medication with or immediately after a meal to help reduce the chance of stomach upset. Consistent timing with meals is important for maintaining stable blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar).

FAQs

What is Trivoglitor 2mg Tablet and what is it used for?Arrow

Trivoglitor 2mg Tablet is an anti-diabetic medicine used to lower high blood sugar levels in people with type 2 diabetes mellitus. This medicine helps to control blood sugar levels.

How does Trivoglitor 2mg Tablet work?Arrow

Trivoglitor 2mg Tablet is a combination of three medicines: Glimepiride, Metformin, and Pioglitazone. Glimepiride is a sulfonylurea which lowers blood glucose by increasing the amount of insulin released by the pancreas. Metformin is a biguanide which works by lowering glucose production in the liver and improving body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which works by increasing insulin sensitivity.

What are the common side effects of Trivoglitor 2mg Tablet?Arrow

Common side effects of Trivoglitor 2mg Tablet include nausea, vomiting, diarrhea, stomach pain, and headache. Inform your doctor if any of these side effects persist or worsen.

Is Trivoglitor 2mg Tablet safe during pregnancy?Arrow

The safety of Trivoglitor 2mg Tablet during pregnancy is not established. Therefore, consult your doctor before using it during pregnancy.

Can I drink alcohol while taking Trivoglitor 2mg Tablet?Arrow

It is not recommended to drink alcohol while taking Trivoglitor 2mg Tablet, as it can increase the risk of low blood sugar levels.

How to store Trivoglitor 2mg Tablet?Arrow

Store Trivoglitor 2mg Tablet at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can Trivoglitor 2mg Tablet cause weight gain?Arrow

Yes, weight gain can occur in some patients due to Pioglitazone present in Trivoglitor 2mg Tablet. Talk to your doctor if you experience excessive weight gain while taking this medicine.

Is Trivoglitor 2mg Tablet safe for the kidneys?Arrow

Trivoglitor 2mg Tablet should be used with caution in patients with kidney disease. Consult your doctor before taking this medicine if you have any kidney problems.

What happens if I miss a dose of Trivoglitor 2mg Tablet?Arrow

If you miss a dose of Trivoglitor 2mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can Trivoglitor 2mg Tablet interact with other medications?Arrow

Yes, Trivoglitor 2mg Tablet can interact with certain other medications. Therefore, inform your doctor about all the medicines you are taking, including over-the-counter medicines and herbal products, before starting this medicine.

What dietary precautions should I follow while taking Trivoglitor 2mg Tablet?Arrow

While taking Trivoglitor 2mg Tablet, you should maintain a healthy diet, exercise regularly, and follow your doctor's advice.

Is Trivoglitor 2mg Tablet safe for children?Arrow

The safety and effectiveness of Trivoglitor 2mg Tablet in children have not been established. Therefore, consult your doctor before giving this medicine to children.

Can I take other anti-diabetic medications with Trivoglitor 2mg Tablet?Arrow

Consult your doctor before taking Trivoglitor 2mg Tablet with other anti-diabetic medications. It may cause a very low blood sugar level when taken in combination with some drugs.

How long does it take for Trivoglitor 2mg Tablet to show its effect?Arrow

It may take a few weeks for Trivoglitor 2mg Tablet to show its effect. Continue taking the medicine as directed to see an improvement in your blood sugar levels.

Is Trivoglitor 2mg Tablet safe for the heart?Arrow

Trivoglitor 2mg Tablet should be used with caution in patients with heart failure, as Pioglitazone present in it may cause fluid retention. Consult your doctor before taking this medicine if you have any heart problems.

References

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DrugBank: Pioglitazone. This entry provides comprehensive information on Pioglitazone, including its mechanism of action, pharmacology, and potential side effects. Pioglitazone is one of the active ingredients in TRIVOGLITOR.

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FDA Drug Label: Actos (Pioglitazone) Label. This is the official FDA label for a product containing pioglitazone. It includes detailed information on its use, dosage, and safety profile.

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European Medicines Agency (EMA): Actos EPAR. This provides a summary of product characteristics and assessment reports for Actos, a pioglitazone-containing medicine, from the European Medicines Agency.

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PMC: Pioglitazone: A Review of Its Use in the Treatment of Type 2 Diabetes Mellitus. This is a review article on the use of pioglitazone in treating type 2 diabetes.

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ScienceDirect: Glimepiride - An overview. This entry offers an overview of glimepiride, its mechanism of action, therapeutic uses, and potential adverse effects. Glimepiride is an active ingredient in TRIVOGLITOR.

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DrugBank: Glimepiride. This entry provides comprehensive information on glimepiride, including its chemical structure, pharmacology, and interactions.

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FDA Drug Label: Amaryl (Glimepiride) Label. This is the official FDA label for Amaryl, a glimepiride-containing product. It includes details on its use, dosage, and safety.

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PMC: Glimepiride: Evidence-Based Facts, Myths, and Paradoxes. This article reviews the evidence-based information about glimepiride, including its efficacy and safety profile.

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ScienceDirect: Voglibose - An Overview. This resource offers an overview of voglibose, its mechanism of action, therapeutic uses, and possible side effects. Voglibose is an active ingredient in TRIVOGLITOR.

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DrugBank: Voglibose. This entry provides detailed information on voglibose, including its chemical structure, pharmacological properties, and interactions.

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J-Stage: Pharmacokinetics and bioavailability of voglibose in relation to food intake in healthy volunteers. This article focuses on the pharmacokinetic properties of voglibose.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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