TRIVOGLIZAR 0.2/2MG TABLET 10'S
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TRIVOGLIZAR 0.2/2MG TABLET 10'STRIVOGLIZAR 0.2/2MG TABLET 10'STRIVOGLIZAR 0.2/2MG TABLET 10'STRIVOGLIZAR 0.2/2MG TABLET 10'S
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TRIVOGLIZAR 0.2/2MG TABLET 10'S

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TRIVOGLIZAR 0.2/2MG TABLET 10'S

By SPECTRA THERAPEUTICS PRIVATE LIMITED

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₹104.72

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Product DetailsArrow

Content Reviewed By:

Dr. Rajesh Sharma

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About TRIVOGLIZAR 0.2/2MG TABLET 10'S

  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains a combination of three active ingredients: Voglibose, Glimepiride and Metformin. Each component works through a different mechanism to effectively lower blood glucose levels.
  • Voglibose is an alpha-glucosidase inhibitor. It works by preventing the breakdown of complex carbohydrates into simple sugars in the intestine, thus slowing down the absorption of glucose into the bloodstream after meals. This helps to reduce postprandial (after-meal) blood sugar spikes.
  • Glimepiride is a sulfonylurea. It stimulates the pancreas to release more insulin, which helps to lower blood sugar levels. Insulin is a hormone that helps glucose move from the blood into cells for energy.
  • Metformin is a biguanide. It works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. This allows the body to use insulin more effectively, further lowering blood sugar levels.
  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is typically taken orally, usually once or twice daily, as prescribed by your doctor. It's crucial to take this medicine at the same time(s) each day and to follow your doctor's instructions regarding dosage and duration of treatment. Common side effects may include nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). It's important to monitor your blood sugar levels regularly while taking this medication and to inform your doctor of any persistent or bothersome side effects. This medication is a prescription drug and should be taken under the guidance of a medical practitioner.

Uses of TRIVOGLIZAR 0.2/2MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)

How TRIVOGLIZAR 0.2/2MG TABLET 10'S Works

  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Voglibose, Glimepiride, and Metformin, each working through different mechanisms to control blood sugar levels.
  • Voglibose, an alpha-glucosidase inhibitor, slows down the absorption of carbohydrates from the small intestine. It competitively inhibits the enzymes (alpha-glucosidases) present in the brush border of the small intestine, which are responsible for breaking down complex carbohydrates into glucose. By inhibiting these enzymes, voglibose delays the postprandial (after-meal) rise in blood glucose levels. This is particularly helpful in controlling blood sugar spikes that occur after eating.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. It works by binding to specific receptors on pancreatic beta cells, leading to the closure of ATP-sensitive potassium channels. This depolarization of the beta cells triggers an influx of calcium ions, which in turn stimulates the release of insulin. Insulin helps glucose enter cells from the blood, thereby lowering blood glucose levels. Glimepiride is effective in reducing fasting blood glucose and postprandial glucose levels.
  • Metformin, a biguanide, works primarily by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues (muscle). It reduces hepatic glucose production by inhibiting gluconeogenesis (the process by which the liver makes glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also enhances insulin sensitivity in peripheral tissues, allowing cells to uptake and utilize glucose more effectively. Additionally, metformin can slow down the absorption of glucose from the intestines.
  • By combining these three medications, TRIVOGLIZAR 0.2/2MG TABLET 10'S provides a comprehensive approach to managing blood sugar levels in individuals with type 2 diabetes. Voglibose controls postprandial glucose spikes, Glimepiride stimulates insulin release, and Metformin reduces hepatic glucose production and improves insulin sensitivity. This synergistic effect helps to maintain stable blood sugar levels throughout the day, reducing the risk of diabetes-related complications. Regular monitoring of blood glucose levels and adherence to a healthy diet and exercise plan are essential for optimal management of diabetes while taking this medication.

Side Effects of TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

Possible side effects of TRIVOGLIZAR 0.2/2MG TABLET may include: * Hypoglycemia (low blood sugar): Sweating, dizziness, headache, blurred vision, shaking, anxiety, irritability, rapid heartbeat. * Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain, constipation, loss of appetite. * Skin reactions: Rash, itching, hives. * Headache * Dizziness * Edema (swelling): Especially in the legs and ankles. * Weight gain * Metallic taste * Upper respiratory tract infection * Urinary tract infection * Blurred vision * Joint pain * Muscle pain * Anemia * Liver problems: Though rare, can cause jaundice (yellowing of skin and eyes), dark urine, abdominal pain. This is not an exhaustive list. Inform your doctor if you experience any unusual symptoms while taking this medication.

Safety Advice for TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Trivoglizar 0.2/2mg Tablet if you are allergic to it or any of its ingredients.

Dosage of TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

  • The recommended dosage of 'TRIVOGLIZAR 0.2/2MG TABLET 10'S' varies depending on individual patient needs, blood glucose levels, and response to treatment. Your physician will determine the appropriate dosage for you. Typically, the starting dose is low and gradually increased to achieve optimal glycemic control. It is crucial to follow your doctor's instructions precisely and not to adjust the dosage on your own.
  • Generally, 'TRIVOGLIZAR 0.2/2MG TABLET 10'S' is taken orally, usually once or twice daily, with meals to minimize gastrointestinal side effects. The tablets should be swallowed whole with a glass of water and not crushed or chewed. Consistent timing of administration is important for maintaining stable blood glucose levels throughout the day.
  • If you miss a dose of 'TRIVOGLIZAR 0.2/2MG TABLET 10'S', take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Doubling the dose can increase the risk of hypoglycemia (low blood sugar).
  • Regular monitoring of blood glucose levels is essential while taking 'TRIVOGLIZAR 0.2/2MG TABLET 10'S'. Your doctor may also recommend periodic blood tests to assess your overall health and the effectiveness of the medication. It's important to communicate openly with your healthcare provider about any side effects or concerns you may experience while taking this medication.
  • Take 'TRIVOGLIZAR 0.2/2MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

  • If you miss a dose of TRIVOGLIZAR 0.2/2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

  • Keep TRIVOGLIZAR 0.2/2MG TAB 1X10 away from the reach of children and pets.
  • Store TRIVOGLIZAR 0.2/2MG TAB 1X10 at room temperature.

Benefits of TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is a combination medicine specifically designed to manage type 2 diabetes effectively. Its triple action targets multiple pathways involved in blood sugar control, offering comprehensive glycemic management.
  • One of the primary benefits of TRIVOGLIZAR is its ability to lower blood sugar levels after meals. Voglibose, an alpha-glucosidase inhibitor, works by slowing down the absorption of carbohydrates from the small intestine. This prevents sharp spikes in blood glucose levels following food intake, which is particularly beneficial for individuals struggling with postprandial hyperglycemia.
  • Glibenclamide, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is crucial for facilitating the uptake of glucose from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, Glibenclamide helps to lower overall blood sugar levels throughout the day.
  • Pioglitazone, a thiazolidinedione, enhances the body's sensitivity to insulin. This means that insulin becomes more effective at transporting glucose into cells. Pioglitazone works by activating PPARγ receptors, which play a key role in glucose and lipid metabolism. This results in improved insulin resistance and better blood sugar control.
  • The combination of these three drugs in TRIVOGLIZAR provides a synergistic effect, addressing different aspects of type 2 diabetes. This multi-pronged approach can lead to better glycemic control compared to using any single drug alone. It helps in achieving target HbA1c levels, a measure of long-term blood sugar control.
  • Improved glycemic control with TRIVOGLIZAR can translate to several long-term health benefits. By keeping blood sugar levels within a healthy range, it helps reduce the risk of developing serious complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • TRIVOGLIZAR can also help improve lipid profiles in some patients. Pioglitazone, in particular, has been shown to have a positive impact on cholesterol levels, potentially reducing the risk of heart disease.
  • Moreover, the use of TRIVOGLIZAR can lead to a reduction in the need for other diabetes medications, including insulin injections, in some individuals. This can simplify the treatment regimen and improve patient compliance.
  • It is important to note that TRIVOGLIZAR should be used as part of a comprehensive diabetes management plan, which includes lifestyle modifications such as diet and exercise. Regular monitoring of blood sugar levels and close consultation with a healthcare provider are also essential for optimizing treatment outcomes and minimizing potential side effects.

How to use TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is an oral medication used to manage type 2 diabetes. It combines three active ingredients to help control blood sugar levels. To ensure the safe and effective use of this medication, follow these guidelines:
  • 1. **Dosage:** Take TRIVOGLIZAR 0.2/2MG TABLET 10'S exactly as prescribed by your doctor. The usual starting dose is one tablet daily, but your doctor may adjust the dosage based on your blood sugar levels and response to treatment. Do not exceed the recommended dose.
  • 2. **Timing:** Take the tablet once daily, preferably with your first main meal of the day. This helps to reduce the risk of gastrointestinal side effects and improves the absorption of the medication.
  • 3. **Administration:** Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your body.
  • 4. **Consistency:** It's crucial to take TRIVOGLIZAR 0.2/2MG TABLET 10'S at the same time each day to maintain consistent blood sugar control. Try to incorporate it into your daily routine.
  • 5. **Diet and Exercise:** TRIVOGLIZAR 0.2/2MG TABLET 10'S works best when combined with a healthy diet and regular exercise. Follow your doctor's or dietitian's recommendations for a diabetes-friendly meal plan and aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • 6. **Monitoring:** Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your healthcare provider assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • 7. **Missed Dose:** If you miss a dose of TRIVOGLIZAR 0.2/2MG TABLET 10'S, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • 8. **Potential Side Effects:** Be aware of potential side effects, such as nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). If you experience any severe or persistent side effects, contact your doctor immediately. Be especially cautious of symptoms of low blood sugar (sweating, shakiness, confusion) and have a quick source of sugar available (e.g., glucose tablets, juice).
  • 9. **Drug Interactions:** Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. TRIVOGLIZAR 0.2/2MG TABLET 10'S can interact with certain medications, potentially affecting its effectiveness or increasing the risk of side effects.
  • 10. **Storage:** Store TRIVOGLIZAR 0.2/2MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets.
  • 11. **Important Note:** This information is intended as a general guide and does not substitute for professional medical advice. Always follow your doctor's instructions and consult with them if you have any questions or concerns about TRIVOGLIZAR 0.2/2MG TABLET 10'S or your diabetes management.

Quick Tips for TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

  • Take TRIVOGLIZAR 0.2/2MG TABLET 10'S as prescribed by your doctor. It's usually taken once or twice daily, preferably before meals, but always follow your doctor's instructions precisely regarding dosage and timing to maintain stable blood sugar levels.
  • Adhere strictly to your prescribed diet. TRIVOGLIZAR works best when combined with a healthy eating plan. Focus on consuming whole grains, lean proteins, and plenty of fruits and vegetables while limiting sugary and processed foods. Regular, balanced meals help optimize the medication's effectiveness.
  • Monitor your blood sugar levels regularly, as directed by your healthcare provider. Keeping a log of your readings will help you understand how TRIVOGLIZAR and your lifestyle choices are affecting your glucose levels. Share this information with your doctor during check-ups to enable any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal remedies you're currently taking. TRIVOGLIZAR can interact with other substances, potentially affecting its efficacy or increasing the risk of side effects. Providing a complete list ensures your doctor can manage any potential interactions safely and effectively.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times in case your blood sugar drops too low. Promptly treating hypoglycemia can prevent serious complications.
  • Engage in regular physical activity. Exercise helps improve insulin sensitivity and lower blood sugar levels, complementing the effects of TRIVOGLIZAR. Aim for at least 30 minutes of moderate-intensity exercise most days of the week, but consult your doctor before starting any new workout routine.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration is essential for overall health and can help regulate blood sugar levels. Water also aids in the proper functioning of your kidneys, which is important for eliminating waste products from your body.
  • Attend all scheduled follow-up appointments with your doctor and other healthcare providers. Regular check-ups are crucial for monitoring your progress, assessing the effectiveness of TRIVOGLIZAR, and making any necessary adjustments to your treatment plan. Don't hesitate to ask questions or voice any concerns you may have.
  • Store TRIVOGLIZAR in a cool, dry place, away from direct sunlight and moisture. Proper storage ensures the medication remains effective and safe to use. Keep it out of reach of children and pets.
  • If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or abdominal discomfort, contact your doctor. They can assess the situation and recommend appropriate measures to manage your symptoms. Do not discontinue TRIVOGLIZAR without consulting your doctor first.

Food Interactions with TRIVOGLIZAR 0.2/2MG TABLET 10'SArrow

  • TRIVOGLIZAR 0.2/2MG TABLET 10'S is generally safe to take with food. However, it is important to maintain a consistent dietary pattern and meal timings while taking this medication. Avoid excessive consumption of sugary or fatty foods, as these can interfere with blood sugar control. Consult your doctor or a registered dietitian for personalized dietary advice tailored to your specific needs and medical condition.

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FAQs

What is TRIVOGLIZAR 0.2/2MG TABLET 10'S and what is it used for?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels when diet and exercise are not enough.

What are the active ingredients present in TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S contains Glimepiride, Metformin and Voglibose as active ingredients.

What are the common side effects of TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

Common side effects of TRIVOGLIZAR 0.2/2MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Can TRIVOGLIZAR 0.2/2MG TABLET 10'S be taken with or without food?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S is usually recommended to be taken with food to avoid stomach upset.

How should TRIVOGLIZAR 0.2/2MG TABLET 10'S be stored?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S should be stored at room temperature, away from direct sunlight and moisture.

Is TRIVOGLIZAR 0.2/2MG TABLET 10'S safe to use during pregnancy?Arrow

The safety of TRIVOGLIZAR 0.2/2MG TABLET 10'S during pregnancy is not established. It should be used only when clearly needed and prescribed by a doctor.

Is TRIVOGLIZAR 0.2/2MG TABLET 10'S safe for breastfeeding women?Arrow

It is not known whether TRIVOGLIZAR 0.2/2MG TABLET 10'S is excreted in breast milk. It is important to consult a doctor before using it while breastfeeding.

What is the dosage of TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

The dosage of TRIVOGLIZAR 0.2/2MG TABLET 10'S is determined by the doctor, depending on the patient's condition and response to treatment.

What happens if I miss a dose of TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

If you miss a dose of TRIVOGLIZAR 0.2/2MG TABLET 10'S, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can TRIVOGLIZAR 0.2/2MG TABLET 10'S interact with other medications?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S can interact with certain other medications. It is important to inform the doctor about all the medications you are taking to avoid any potential interactions.

What are the symptoms of an overdose of TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

Symptoms of an overdose of TRIVOGLIZAR 0.2/2MG TABLET 10'S may include hypoglycemia (low blood sugar), nausea, vomiting, and abdominal pain.

What precautions should be followed while taking TRIVOGLIZAR 0.2/2MG TABLET 10'S?Arrow

While taking TRIVOGLIZAR 0.2/2MG TABLET 10'S, monitor blood sugar levels regularly, maintain a healthy diet, exercise regularly, and follow your doctor's advice.

Can TRIVOGLIZAR 0.2/2MG TABLET 10'S cause weight gain?Arrow

Weight gain can occur in some patients taking TRIVOGLIZAR 0.2/2MG TABLET 10'S. It is important to monitor your weight and consult a doctor if you experience significant weight gain.

Is TRIVOGLIZAR 0.2/2MG TABLET 10'S safe for patients with kidney disease?Arrow

TRIVOGLIZAR 0.2/2MG TABLET 10'S should be used with caution in patients with kidney disease, as it can worsen kidney function. It is important to consult a doctor to adjust the dosage or consider alternative treatments.

Can I take TRIVOGLIZAR 0.2/2MG TABLET 10'S if I am taking other medications?Arrow

Tell your doctor about all the medications, vitamins, or herbal supplements you’re taking. This is because TRIVOGLIZAR 0.2/2MG TABLET 10'S can interact with some medicines.

References

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DrugBank: Glimepiride and Metformin Combination - This entry provides detailed information on the combination drug, including its pharmacology, uses, and interactions. (Note: Trivoglizar is a brand name for a medication containing Glimepiride, Metformin, and Voglibose)

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PubMed Central (PMC) - Search for articles related to Glimepiride, Metformin, and Voglibose. Use specific keywords like 'Glimepiride metformin voglibose combination' or individual ingredient names with terms like 'pharmacokinetics', 'clinical trial', 'mechanism of action'.

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European Medicines Agency (EMA) - Search for scientific assessments and regulatory information on Glimepiride and Metformin containing products. Though Voglibose is less common in Europe, information on the other two ingredients will be available.

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FDA Drugs@FDA - This resource might not have specific information on Trivoglizar directly (since it appears to be more common outside the US), but searching for Glimepiride and Metformin will provide relevant documents related to their approval and usage.

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ScienceDirect - Use this database to find research articles related to the individual components and their combined effects on diabetes management. Keywords: Glimepiride, Metformin, Voglibose, Type 2 Diabetes, Combination Therapy.

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Thieme E-Journals - Search for articles related to Glimepiride, Metformin, and Voglibose, focusing on clinical studies and pharmacological properties.

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Wiley Online Library - Search for research papers and reviews focusing on the therapeutic effects and safety profiles of the individual drugs and their combination.

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Electronic Medicines Compendium (eMC) - Search for the UK-approved medications. While Trivoglizar may not be listed, searching for Glimepiride and Metformin will give you information about similar combination therapies.

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ClinicalTrials.gov - Search for clinical trials involving Glimepiride, Metformin, and Voglibose, either individually or in combination, to find study protocols and results.

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PubChem - Search for the individual ingredients (Glimepiride, Metformin, Voglibose) to find their chemical structures, properties, and related compounds.

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Ratings & Review

Medkart pharmacy is doing good on saving money of customer and good work on aware to people about generic medicines.

Rinkal Surti

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Reviewed on 23-11-2022

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(5/5)

Best for medicine and helpfull.😊

Dilip Darji

•

Reviewed on 02-02-2024

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(5/5)

Should display more medical verities.

Ronak Ankola

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Reviewed on 25-07-2023

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(2/5)

Very cheap, helpful, friendly service

Milind Patel

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Reviewed on 10-02-2023

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(5/5)

All drugs available good service

Jayvadan Lalpara

•

Reviewed on 23-01-2024

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(5/5)


Marketer / Manufacturer Details

SPECTRA THERAPEUTICS PRIVATE LIMITED

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India

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Disclaimer

Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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