HUMINSULIN 30/70 PENFILL 3 ML

How HUMINSULIN 30/70 PENFILL 3 ML Works

• HUMINSULIN 30/70 PENFILL 3 ML is a premixed insulin formulation containing 30% rapid-acting (soluble) insulin and 70% intermediate-acting (isophane) insulin. This combination is designed to help manage blood sugar levels in people with diabetes by mimicking the body's natural insulin release pattern. The rapid-acting component covers insulin needs at mealtimes, while the intermediate-acting component provides a longer-lasting background insulin coverage.
• Here's a breakdown of how each component works:
• **Rapid-Acting Insulin (30%):** This type of insulin is quickly absorbed into the bloodstream after injection. It begins to lower blood sugar levels within 30 minutes, peaks in about 2-4 hours, and lasts for approximately 6-8 hours. Its primary role is to control the rise in blood glucose that occurs after eating a meal. By injecting HUMINSULIN 30/70 before a meal, the rapid-acting insulin helps to process the carbohydrates and sugars from the food, preventing a sharp spike in blood sugar.
• **Intermediate-Acting Insulin (70%):** This type of insulin is absorbed more slowly due to the presence of protamine, which prolongs its action. It starts working within 1-2 hours, peaks in 4-12 hours, and lasts for up to 16-24 hours. The intermediate-acting insulin provides a basal level of insulin, which helps to keep blood sugar levels stable between meals and overnight. It supplements the rapid-acting insulin by providing a longer-lasting effect.
• When you inject HUMINSULIN 30/70, both types of insulin are released into your bloodstream. The rapid-acting insulin immediately starts to lower your blood sugar after your meal, while the intermediate-acting insulin gradually takes effect to maintain stable blood sugar levels between meals. This combined action helps to control blood sugar throughout the day and night.
• It is crucial to use HUMINSULIN 30/70 as prescribed by your doctor. The dosage and timing of injections are determined based on your individual needs, including your diet, activity level, and blood sugar levels. Regular monitoring of blood glucose is essential to ensure that HUMINSULIN 30/70 is effectively controlling your blood sugar and to make any necessary adjustments to your treatment plan in consultation with your healthcare provider.
• This product is delivered via a pen device, which allows for accurate and convenient dosing. Always follow your doctor's instructions and the instructions provided with the pen device for proper injection technique and safety precautions. Proper storage of the penfill is also important to maintain the efficacy of the insulin.

Like all medicines, Huminsulin 30/70 Penfill can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Hypoglycemia (low blood sugar): This is the most common side effect. Severe hypoglycemia can lead to unconsciousness and, in very rare circumstances, may be fatal. * Local allergy: Redness, swelling, or itching at the injection site. * Lipodystrophy: Changes in fatty tissue at the injection site (either thickening or pitting of the skin). **Uncommon side effects (may affect up to 1 in 100 people):** * Systemic allergy: Generalized allergic reaction causing skin rash, shortness of breath, wheezing, reduction in blood pressure, fast pulse, or sweating. * Edema: Swelling of ankles and other joints. **Rare side effects (may affect up to 1 in 1,000 people):** * Diabetic ketoacidosis can occur if insulin is stopped or the dose is not high enough. Symptoms include nausea, vomiting, abdominal pain, drowsiness, rapid breathing, unusual thirst, and high levels of glucose and ketones in the urine. **Very rare side effects (may affect up to 1 in 10,000 people):** * Vision problems can occur when first starting insulin treatment. **Other Possible Side Effects:** * Weight gain * Injection site reactions (pain, bleeding, bruising) * Peripheral neuropathy (nerve damage causing pain, numbness, and tingling) **If you experience any side effects, especially severe allergic reactions or signs of ketoacidosis, seek immediate medical attention.**

• If you miss a dose of Huminsulin 30/70, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of hypoglycemia (low blood sugar).

• Keep HUMINSULIN 30/70 PENFILL 3ML away from the reach of children and pets.
• Store HUMINSULIN 30/70 PENFILL 3ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** HUMINSULIN 30/70 is a premixed insulin containing 30% rapid-acting and 70% intermediate-acting insulin. This means it starts working quickly to cover mealtime glucose and also provides a background level of insulin that lasts longer. Make sure you understand how each component works to manage your blood sugar effectively. Knowing this can help you time your meals and activities appropriately. Discuss with your healthcare provider to tailor the timing of your insulin injections to your specific needs and lifestyle. Consistent timing is key to achieving optimal blood sugar control.
• **Proper Storage is Crucial:** Always store your HUMINSULIN 30/70 Penfill in the refrigerator (2°C to 8°C or 36°F to 46°F) until you're ready to use it. Once in use, the pen can be stored at room temperature (below 30°C or 86°F) for up to 28 days. Avoid exposing the insulin to extreme temperatures or direct sunlight, as this can degrade its effectiveness. Keeping a record of when you started using a pen can help you remember when to discard it. Always inspect the insulin before each use; it should be clear and colorless. Discard if it appears cloudy, discolored, or contains particles.
• **Prime the Pen Before Each Injection:** Priming the pen is essential to ensure you're getting an accurate dose. Before each injection, dial 2 units and then press the injection button until a drop of insulin appears at the needle tip. Repeat this process until you see a consistent drop. This step removes any air bubbles that may be present in the pen and ensures that you receive the correct dose of insulin. Air bubbles can lead to inaccurate dosing and inconsistent blood sugar control. Make sure to use a new needle for each injection to maintain hygiene and prevent contamination.
• **Rotate Injection Sites Regularly:** To prevent lipohypertrophy (thickening of the skin), rotate your injection sites within the same general area (e.g., abdomen, thigh, or upper arm). Keep a record of your injection sites to ensure you're not using the same spot too frequently. Consistent rotation helps maintain consistent insulin absorption and reduces the risk of skin changes. Injecting into areas with lipohypertrophy can affect insulin absorption and lead to unpredictable blood sugar levels. Consult your healthcare provider for guidance on proper injection site rotation techniques.
• **Monitor Your Blood Sugar Levels:** Regularly monitor your blood sugar levels as directed by your healthcare provider. This will help you understand how HUMINSULIN 30/70 is working for you and whether any adjustments to your dosage or timing are needed. Keep a log of your blood sugar readings, insulin doses, meal times, and physical activity to identify patterns and trends. Share this information with your healthcare team to optimize your diabetes management plan. Regular monitoring empowers you to make informed decisions about your health and helps prevent both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).
• **Be Aware of Hypoglycemia Symptoms:** Hypoglycemia (low blood sugar) is a potential side effect of insulin therapy. Be aware of the symptoms, which can include shakiness, sweating, dizziness, confusion, and rapid heartbeat. Always carry a source of fast-acting carbohydrates, such as glucose tablets or juice, to treat low blood sugar immediately. If you experience frequent episodes of hypoglycemia, discuss this with your healthcare provider to adjust your insulin dosage or meal plan. Educate your family and friends about the signs of hypoglycemia and how to assist you in case of an emergency. Wearing a medical alert bracelet or carrying an ID card can also be helpful in alerting others to your condition.
• **Follow a Consistent Meal Plan:** Since HUMINSULIN 30/70 contains both rapid-acting and intermediate-acting insulin, it's important to follow a consistent meal plan and eat regular meals at set times each day. This helps to match the insulin's action with the food you eat, preventing fluctuations in blood sugar levels. Work with a registered dietitian or certified diabetes educator to develop a meal plan that meets your individual needs and preferences. Pay attention to portion sizes, carbohydrate content, and the timing of your meals. Consistency in your eating habits can significantly improve your blood sugar control and reduce the risk of both high and low blood sugar levels.

• It is important to have regular meals and snacks, and to monitor your blood glucose levels regularly.
• The timing of insulin injection and food intake should be coordinated to maintain optimal blood glucose control.
• Consult your doctor or diabetes educator for specific advice on how to adjust your insulin dose based on your dietary intake.