METGEM 500MG TABLET 10'S
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METGEM 500MG TABLET 10'S
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METGEM 500MG TABLET 10'S

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METGEM 500MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

22.51

₹19.13

15.02 % OFF

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About METGEM 500MG TABLET 10'S

  • METGEM 500MG TABLET 10'S is a medication primarily used to manage blood sugar levels in individuals with type 2 diabetes. It contains Metformin Hydrochloride as its active ingredient, a well-established and widely prescribed oral antihyperglycemic agent.
  • Metformin works by decreasing glucose production in the liver, improving insulin sensitivity, and reducing glucose absorption in the intestines. This triple action helps lower both basal and postprandial blood glucose levels. It is often prescribed as a first-line treatment for type 2 diabetes, particularly in overweight individuals, as it also has a tendency to promote modest weight loss.
  • Each METGEM 500MG tablet contains 500mg of Metformin Hydrochloride. The inactive ingredients may vary depending on the manufacturer, but generally include excipients like povidone, magnesium stearate, and film-coating agents to aid in tablet formation, stability, and ease of swallowing. It is crucial to review the package insert for a comprehensive list of ingredients, especially if you have known allergies or sensitivities.
  • METGEM 500MG TABLET is usually taken orally with meals to minimize gastrointestinal side effects. Dosage is determined by a healthcare professional based on individual needs and response to treatment. Common side effects include nausea, vomiting, diarrhea, and abdominal discomfort, particularly when starting treatment. Lactic acidosis, a rare but serious complication, can occur, especially in individuals with kidney problems. Regular monitoring of kidney function is recommended. Patients should discuss all medical conditions and medications with their doctor before starting METGEM 500MG.

Uses of METGEM 500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Treatment of polycystic ovary syndrome (PCOS)
  • Treatment of gestational diabetes (high blood sugar during pregnancy)
  • Improving insulin sensitivity
  • Reducing the risk of heart disease (in diabetic patients)
  • Aiding in weight management (in some patients)
  • Management of pre-diabetes

How METGEM 500MG TABLET 10'S Works

  • METGEM 500MG TABLET 10'S is a medication primarily used to manage blood sugar levels in individuals with type 2 diabetes. Its effectiveness stems from the active ingredient, Metformin, which operates through several key mechanisms to improve glycemic control.
  • Firstly, Metformin reduces glucose production in the liver. The liver is a major source of glucose in the body, and in individuals with type 2 diabetes, it often produces excessive amounts. Metformin inhibits hepatic gluconeogenesis, the process by which the liver creates glucose from non-carbohydrate sources. By suppressing this process, Metformin lowers the amount of glucose released into the bloodstream, helping to keep blood sugar levels in check. This is achieved through complex biochemical pathways involving the enzyme AMPK (adenosine monophosphate-activated protein kinase). Metformin activates AMPK, which in turn regulates glucose metabolism and reduces hepatic glucose output.
  • Secondly, METGEM 500MG TABLET 10'S enhances insulin sensitivity in peripheral tissues, primarily muscle tissue. Insulin is a hormone that helps glucose enter cells from the bloodstream, where it can be used for energy. In type 2 diabetes, cells often become resistant to insulin's effects, requiring more insulin to achieve the same glucose-lowering effect. Metformin helps to overcome this resistance by improving the ability of insulin to facilitate glucose uptake into muscle cells. This leads to better utilization of glucose and a reduction in blood sugar levels. The precise mechanisms by which Metformin improves insulin sensitivity are still being investigated, but it is believed to involve changes in insulin signaling pathways and glucose transporter proteins.
  • Thirdly, Metformin slows down the absorption of glucose from the intestines. After a meal, carbohydrates are broken down into glucose, which is then absorbed into the bloodstream. Metformin delays this absorption process, preventing rapid spikes in blood sugar levels after eating. This effect contributes to overall glycemic control and helps to reduce postprandial hyperglycemia (high blood sugar after meals).
  • In summary, METGEM 500MG TABLET 10'S works through a multi-faceted approach to lower blood sugar levels. It reduces glucose production in the liver, enhances insulin sensitivity in peripheral tissues, and slows down glucose absorption from the intestines. These combined effects help to improve glycemic control in individuals with type 2 diabetes, reducing the risk of long-term complications associated with high blood sugar.
  • It's important to note that METGEM 500MG TABLET 10'S is typically used in conjunction with lifestyle modifications such as diet and exercise. These lifestyle changes are crucial for managing diabetes and maximizing the effectiveness of the medication. Regular monitoring of blood sugar levels is also necessary to ensure that the medication is working properly and to adjust the dosage as needed, under the guidance of a healthcare professional.

Side Effects of METGEM 500MG TABLET 10'SArrow

Common side effects of METGEM 500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. Less common but potentially serious side effects include lactic acidosis (symptoms may include rapid breathing, stomach pain, muscle cramps), liver problems, and decreased Vitamin B12 absorption. Allergic reactions such as rash, itching, or swelling are also possible. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for METGEM 500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use if you are allergic to metformin or any of the ingredients in METGEM 500MG TABLET 10'S.

Dosage of METGEM 500MG TABLET 10'SArrow

  • The recommended dosage of METGEM 500MG TABLET 10'S varies depending on individual patient needs, kidney function, and other medications being taken. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Typically, the starting dose for adults is 500 mg once or twice daily, administered with meals to minimize gastrointestinal side effects. Your physician may gradually increase the dosage based on your blood glucose levels, usually in increments of 500 mg weekly, up to a maximum of 2000 mg per day, divided into multiple doses. Some patients may benefit from higher doses, up to 2550 mg per day, but this is less common and requires careful monitoring. The extended-release (XR) formulation of METGEM 500MG TABLET 10'S allows for once-daily dosing, typically taken with the evening meal. The specific dosage and timing will be determined by your doctor. Do not crush, chew, or break the extended-release tablets; they should be swallowed whole. Regular monitoring of blood glucose levels is essential to determine the effectiveness of the medication and adjust the dosage accordingly. It is important to inform your doctor about any other medications, including over-the-counter drugs and herbal supplements, as they may interact with METGEM 500MG TABLET 10'S. Patients with kidney problems may require lower doses. Missed doses should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In such cases, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to compensate for a missed one. Take 'METGEM 500MG TABLET 10'S' only as per the prescription by your physician only.
  • Dosage adjustments are made based on individual response and tolerance. Elderly patients may require lower doses due to age-related decline in kidney function. Routine kidney function tests are recommended, especially in older adults. The maximum recommended daily dose should not be exceeded without consulting your healthcare provider. The safety and efficacy of METGEM 500MG TABLET 10'S in children have not been definitively established, and its use in pediatric patients is generally limited to specific circumstances under close medical supervision. If you experience any unusual side effects, such as persistent nausea, vomiting, abdominal pain, or unexplained fatigue, contact your doctor immediately. These symptoms could indicate a serious adverse reaction and may require immediate medical attention. Always consult with your doctor or pharmacist if you have any questions or concerns regarding your medication or dosage.

What if I miss my dose of METGEM 500MG TABLET 10'S?Arrow

  • If you miss a dose of METGEM 500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store METGEM 500MG TABLET 10'S?Arrow

  • Keep METGEM 500MG TAB 1X10 away from the reach of children and pets.
  • Store METGEM 500MG TAB 1X10 at room temperature.

Benefits of METGEM 500MG TABLET 10'SArrow

  • METGEM 500MG TABLET 10'S is primarily prescribed for the management of type 2 diabetes mellitus. It helps to control high blood sugar levels, which is crucial in preventing long-term complications associated with diabetes, such as kidney damage, nerve problems, vision loss, and cardiovascular diseases. By effectively lowering blood glucose, METGEM contributes to overall health and well-being in individuals with type 2 diabetes.
  • One of the key benefits of METGEM 500MG TABLET 10'S is its ability to improve the body's response to insulin. In type 2 diabetes, the body either does not produce enough insulin or the cells become resistant to insulin's effects. METGEM helps to overcome insulin resistance, allowing the body to use insulin more effectively to transport glucose from the bloodstream into the cells for energy. This mechanism of action is vital for maintaining stable blood sugar levels and reducing the risk of hyperglycemia.
  • METGEM 500MG TABLET 10'S also aids in reducing the amount of glucose produced by the liver. The liver can sometimes produce excessive amounts of glucose, especially during periods of fasting or between meals, which can lead to elevated blood sugar levels. METGEM works to suppress this overproduction of glucose, further contributing to better glycemic control. This is particularly beneficial for individuals who experience significant fluctuations in their blood sugar levels throughout the day.
  • Furthermore, METGEM 500MG TABLET 10'S can have a positive impact on cholesterol levels. Studies have shown that it can help lower LDL (bad) cholesterol and triglyceride levels while potentially increasing HDL (good) cholesterol. This effect on lipid profile is an added advantage, as individuals with diabetes are often at a higher risk of developing cardiovascular diseases. By improving cholesterol levels, METGEM contributes to heart health and reduces the risk of cardiovascular complications.
  • In addition to its primary function of controlling blood sugar, METGEM 500MG TABLET 10'S can also assist with weight management. Unlike some other diabetes medications that can cause weight gain, METGEM is often associated with weight loss or weight neutrality. This can be particularly beneficial for individuals with type 2 diabetes who are also overweight or obese, as weight management is an important aspect of diabetes management. The mechanism behind this effect is not fully understood but may be related to its impact on insulin sensitivity and glucose metabolism.
  • METGEM 500MG TABLET 10'S is often used in combination with other diabetes medications to achieve optimal blood sugar control. It can be safely combined with other oral antidiabetic agents or insulin to provide a comprehensive approach to diabetes management. This allows healthcare providers to tailor treatment plans to meet the individual needs of each patient, ensuring the best possible outcomes.
  • METGEM 500MG TABLET 10'S is available in various formulations, including immediate-release and extended-release tablets. The extended-release formulation provides a longer duration of action, allowing for once-daily dosing, which can improve adherence to the medication regimen. This is particularly convenient for individuals who have difficulty remembering to take multiple doses of medication throughout the day. Improved adherence leads to better blood sugar control and overall health outcomes.
  • Finally, METGEM 500MG TABLET 10'S is a well-established and widely used medication with a proven track record of safety and efficacy. It has been used for many years in the treatment of type 2 diabetes and has been extensively studied in clinical trials. This extensive experience provides confidence in its ability to effectively manage blood sugar levels and reduce the risk of diabetes-related complications. Its long-standing use also means that healthcare providers are very familiar with its use and potential side effects, allowing for informed and effective management of treatment.

How to use METGEM 500MG TABLET 10'SArrow

  • METGEM 500MG TABLET 10'S is an oral medication primarily used to manage blood sugar levels in individuals with type 2 diabetes. It's crucial to take this medication exactly as prescribed by your doctor. Typically, it is taken with meals to minimize potential gastrointestinal side effects. The usual starting dose is often lower, and gradually increased based on your blood sugar response and tolerance. Never adjust your dosage without consulting your healthcare provider.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. It's best to take METGEM 500MG TABLET 10'S at the same time each day to maintain consistent blood sugar control. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking METGEM 500MG TABLET 10'S, it's important to adhere to a healthy diet and exercise regularly. This medication works best when combined with lifestyle modifications. Regularly monitor your blood sugar levels as directed by your doctor, and keep them informed of any changes or concerns. It's also important to inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with METGEM 500MG TABLET 10'S. Be aware of potential side effects, such as nausea, vomiting, diarrhea, and abdominal discomfort. If these persist or worsen, consult your doctor promptly. Attend all scheduled follow-up appointments to monitor your progress and address any potential issues.
  • Store METGEM 500MG TABLET 10'S at room temperature, away from moisture and heat. Keep out of reach of children. If you experience any severe side effects, such as difficulty breathing, rapid heartbeat, or severe abdominal pain, seek immediate medical attention. This medication is not a substitute for insulin in type 1 diabetes and should only be used under the guidance of a healthcare professional for type 2 diabetes.

Quick Tips for METGEM 500MG TABLET 10'SArrow

  • Take METGEM 500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting them. This ensures you maintain consistent blood sugar control and avoid potential complications.
  • It is best to take METGEM 500MG TABLET 10'S with meals to reduce the chances of stomach upset. This will improve your tolerance to the medicine and help you stick to your treatment plan.
  • Follow a healthy diet and exercise regularly while taking METGEM 500MG TABLET 10'S. This combination of medication, diet, and exercise provides the best results in managing your blood sugar levels and overall health.
  • Monitor your blood sugar levels regularly as advised by your doctor. This helps you understand how METGEM 500MG TABLET 10'S is working for you and allows your doctor to make necessary adjustments to your treatment plan.
  • Stay hydrated by drinking plenty of water throughout the day while taking METGEM 500MG TABLET 10'S. Adequate hydration supports kidney function and helps prevent potential side effects associated with the medication. It's also beneficial for overall health and wellbeing. Inform your doctor immediately if you experience any unusual symptoms or side effects. Early detection and management of side effects are crucial for your safety and well-being. Do not ignore any discomfort or changes in your health condition.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia). Know how to manage these situations, especially when you're on medication for diabetes. Hypoglycemia can cause shakiness, sweating, and confusion, while hyperglycemia can cause increased thirst and frequent urination. Understanding these signs can help you take prompt action and prevent serious complications.

Food Interactions with METGEM 500MG TABLET 10'SArrow

  • METGEM 500MG TABLET 10'S can be taken with or without food, but it is generally recommended to take it with meals to reduce the possibility of stomach upset. Consistent timing with meals is advisable.
  • Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of lactic acidosis, a serious side effect.
  • There are no specific food restrictions, but maintaining a balanced diet is important for managing blood sugar levels effectively.

FAQs

What is METGEM 500MG TABLET and what is it used for?Arrow

METGEM 500MG TABLET contains metformin, used to treat type 2 diabetes. It works by making the body more sensitive to insulin and reducing the amount of glucose produced by the liver.

How should I take METGEM 500MG TABLET?Arrow

Always take METGEM 500MG TABLET as prescribed by your doctor. Take it with food and drink plenty of water.

What are the common side effects of METGEM 500MG TABLET?Arrow

Common side effects of METGEM 500MG TABLET include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is METGEM 500MG TABLET safe for people with kidney problems?Arrow

People with kidney problems should talk to their doctor before taking METGEM 500MG TABLET, as it can worsen kidney problems.

How should I store METGEM 500MG TABLET?Arrow

Store METGEM 500MG TABLET at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.

Can METGEM 500MG TABLET be taken without food?Arrow

It is always recommended to take METGEM 500MG TABLET with food to avoid stomach upset.

What to do if I overdose on METGEM 500MG TABLET?Arrow

If you suspect an overdose of METGEM 500MG TABLET, contact your doctor immediately or go to the nearest hospital.

Can I consume alcohol while taking METGEM 500MG TABLET?Arrow

Alcohol consumption should be avoided while taking METGEM 500MG TABLET, as it can increase the risk of lactic acidosis, a serious condition.

Is METGEM 500MG TABLET safe during pregnancy?Arrow

Consult your doctor before taking METGEM 500MG TABLET during pregnancy.

Is METGEM 500MG TABLET safe during breastfeeding?Arrow

Consult your doctor before taking METGEM 500MG TABLET during breastfeeding.

Does METGEM 500MG TABLET interact with other medications?Arrow

METGEM 500MG TABLET can interact with some other medications. Therefore, tell your doctor about all the medications you are taking.

How long does it take for METGEM 500MG TABLET to start working?Arrow

It may take a few days or weeks for METGEM 500MG TABLET to start working.

Can METGEM 500MG TABLET cause weight loss?Arrow

METGEM 500MG TABLET may cause weight loss in some people, but it does not happen to everyone.

What are the alternatives to METGEM 500MG TABLET?Arrow

Alternatives to METGEM 500MG TABLET include other metformin brands, sulfonylureas, glitazones, and insulin.

Does METGEM 500MG TABLET help in treating PCOS (Polycystic Ovary Syndrome)?Arrow

METGEM 500MG TABLET can be used in the treatment of PCOS, especially in women with insulin resistance. It can help improve ovulation and increase the chances of pregnancy.

References

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DrugBank: Metformin. Comprehensive information on metformin, including its mechanism of action, uses, and interactions. (Ingredient: Metformin)

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FDA Label: Metformin Hydrochloride Tablets, prescribing information. U.S. Food and Drug Administration. (Ingredient: Metformin)

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European Medicines Agency (EMA): Glucophage (metformin) EPAR. Public Assessment Report on metformin-containing medicine. (Ingredient: Metformin)

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Effect of metformin on gut microbiota: The evidence from basic science and clinical research. (Ingredient: Metformin)

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ScienceDirect: Metformin. Overview of metformin's pharmacology, mechanism of action, and clinical applications. (Ingredient: Metformin)

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