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PANGRAF 1MG CAPSULE 10'S
PANGRAF 1MG CAPSULE 10'S
By MANKIND PHARMA LIMITED
MRP
₹
454.94
₹386.7
15 % OFF
₹38.67 Only /
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Composition
Product Details
About PANGRAF 1MG CAPSULE 10'S
- PANGRAF 1MG CAPSULE 10'S contains the active substance Tacrolimus, an immunosuppressant belonging to the calcineurin inhibitor class. This medication, often used alongside other drugs, helps prevent organ rejection following liver, kidney, heart, or other transplants. Its primary function is to modulate the body's immune response, facilitating the acceptance of the transplanted organ and preventing the immune system from attacking it. By suppressing specific immune cells, PANGRAF 1MG CAPSULE 10'S increases the likelihood of successful transplantation.
- Before taking PANGRAF 1MG CAPSULE 10'S, it's crucial to inform your doctor about any existing allergies, especially to tacrolimus or any other components of the medication. Additionally, disclose any history of liver or heart disease to your physician before starting treatment. Promptly notify your doctor if you experience any concerning symptoms after starting the medication, such as fever, unexplained bruising (appearing as red dots), unusual fatigue, confusion, jaundice (yellowing of the skin or eyes), reduced urine output, vision disturbances, or seizures. These symptoms may indicate serious side effects requiring immediate medical attention.
- While taking PANGRAF 1MG CAPSULE 10'S, it's important to minimize exposure to sunlight and UV light by wearing protective clothing and using sunscreen with a high sun protection factor. Immunosuppressive therapies can increase the risk of malignant skin changes, making sun protection essential. Diarrhea is a potential side effect of this medication; if you experience diarrhea lasting more than a day, inform your physician. If vaccinations are required, consult your doctor before receiving them, as PANGRAF 1MG CAPSULE 10'S can affect the immune response to vaccines. Regular monitoring and communication with your healthcare provider are vital for managing potential side effects and ensuring the medication's effectiveness.
- This medication requires regular blood tests to monitor the levels of tacrolimus in your system and to check for any adverse effects on your kidney or liver function. Consistent follow-up appointments are necessary to adjust the dosage and manage potential complications. It is essential to adhere strictly to the prescribed dosage and schedule to maintain therapeutic levels and prevent rejection episodes. Avoid taking any other medications or herbal supplements without consulting your doctor, as they may interact with PANGRAF 1MG CAPSULE 10'S.
Uses of PANGRAF 1MG CAPSULE 10'S
- Prevent organ transplant rejections by suppressing the body's immune system from attacking the new organ.
How PANGRAF 1MG CAPSULE 10'S Works
- PANGRAF 1MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
- PANGRAF 1MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, PANGRAF 1MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, PANGRAF 1MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of PANGRAF 1MG CAPSULE 10'S in skin disorders is not fully understood.
Side Effects of PANGRAF 1MG CAPSULE 10'S
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Swelling in the arm or leg
- Hair loss
- Itchy skin
- Constipation, diarrhea
- Nausea, vomiting
- Anemia
- Headache
- Cough
- Increased or decreased heartbeats
- GI bleeding
- Liver Injury
- Seizure
- Acute kidney failure
- Lung infection or respiratory problems
Safety Advice for PANGRAF 1MG CAPSULE 10'S
Pregnancy
CONSULT YOUR DOCTORBased on animal studies, PANGRAF 1MG CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.
Dosage of PANGRAF 1MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 1MG CAPSULE 10'S, taking into account your specific medical condition, its severity, and other relevant factors. It is crucial to adhere strictly to your doctor's prescription when taking PANGRAF 1MG CAPSULE 10'S.
- To ensure optimal absorption and effectiveness, do not open, break, crush, or chew the capsules. Instead, swallow each capsule whole with a glass of water. For best results, take PANGRAF 1MG CAPSULE 10'S on an empty stomach. This means consuming the capsules either at least 1 hour before a meal or 2 to 3 hours after eating.
- Consistency in timing is also important. Try to take PANGRAF 1MG CAPSULE 10'S at the same time each day to maintain a steady level of medication in your system. If you have any questions or concerns about the dosage or how to take PANGRAF 1MG CAPSULE 10'S, consult with your doctor or pharmacist for clarification.
How to store PANGRAF 1MG CAPSULE 10'S?
- Keep PANGRAF 1MG CAP 1X10 away from the reach of children and pets.
- Store PANGRAF 1MG CAP 1X10 at room temperature.
Benefits of PANGRAF 1MG CAPSULE 10'S
- PANGRAF 1MG CAPSULE 10'S is a medication that functions by weakening the body's immune system. It achieves this immunosuppression through a complex mechanism that primarily targets T-lymphocytes. These are crucial cells in the immune system responsible for identifying and attacking foreign substances.
- Specifically, PANGRAF 1MG CAPSULE 10'S inhibits the activation and proliferation of T-lymphocytes, effectively reducing their ability to mount an immune response. Additionally, it suppresses the T-helper-cell-dependent B-cell response. B-cells are responsible for producing antibodies, and T-helper cells are required for their activation.
- The drug's mechanism of action involves binding to an intracellular protein called FKBP-12. This binding forms a complex known as tacrolimus-FKBP. This complex then inhibits the activity of an enzyme called calcineurin phosphatase, a critical component in the signaling pathway that leads to T-cell activation.
- By inhibiting calcineurin phosphatase, PANGRAF 1MG CAPSULE 10'S effectively blocks the formation of T cells and subsequent immune responses. This makes it valuable in preventing organ rejection after transplants and treating autoimmune diseases where the immune system attacks the body's own tissues.
How to use PANGRAF 1MG CAPSULE 10'S
- Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 1MG CAPSULE 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to always take PANGRAF 1MG CAPSULE 10'S exactly as prescribed by your doctor. Do not attempt to open, break, crush, or chew the capsules. Instead, swallow the capsule whole with a full glass of water. To ensure optimal absorption and effectiveness, take these capsules on an empty stomach, ideally at least 1 hour before a meal or 2 to 3 hours after eating.
- Consistency in timing is important. Try to take the capsule at the same time each day to maintain a steady level of medication in your system. If you have any difficulty swallowing the capsule whole, discuss it with your doctor or pharmacist. They may be able to offer alternative formulations or strategies to help you take your medication correctly. Never alter the prescribed dosage or stop taking PANGRAF 1MG CAPSULE 10'S without first consulting your doctor, as this could have serious consequences for your health and treatment outcome.
FAQs
What if I missed a dose of PANGRAF 1MG CAPSULE 10'S?
Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.
What should you not use with PANGRAF 1MG CAPSULE 10'S?
Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.
How long do I need to take PANGRAF 1MG CAPSULE 10'S after a transplant?
The duration of PANGRAF 1MG CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, PANGRAF 1MG CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.
Can PANGRAF 1MG CAPSULE 10'S increase the risk of infections?
Yes, PANGRAF 1MG CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.
Can PANGRAF 1MG CAPSULE 10'S affect kidney function?
PANGRAF 1MG CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.
Should I follow any dietary restrictions while taking PANGRAF 1MG CAPSULE 10'S?
PANGRAF 1MG CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.
Does PANGRAF 1MG CAPSULE 10'S interact with other drugs?
PANGRAF 1MG CAPSULE 10'S has NULL interaction with other drugs.
What advice should I follow while using PANGRAF 1MG CAPSULE 10'S?
Do not eat grapefruit or drink grapefruit juice while you are using PANGRAF 1MG CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.
What molecule/combination is used for making PANGRAF 1MG CAPSULE 10'S?
TACROLIMUS is molecule/combination used for making PANGRAF 1MG CAPSULE 10'S.
For which ailments/diseases/conditions is PANGRAF 1MG CAPSULE 10'S prescribed?
PANGRAF 1MG CAPSULE 10'S is prescribed for Nephrology and Infectious Diseases.
References
Ratings & Review
Have a great place to purchase medicine.
Bipin Lathiya official
•
Reviewed on 14-12-2022
(5/5)
Good service. Public relations are very good.
Pallav Bhatt
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Reviewed on 22-11-2022
(5/5)
Good and cost effective medicines
Vishal Chaudhari
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Reviewed on 15-02-2024
(5/5)
Good place to get your generic medicines.
shreyas potdar
•
Reviewed on 09-04-2024
(5/5)
Discount on medicine is good But OTC discount is zero and very low
Abhishek Solanki
•
Reviewed on 05-12-2022
(3/5)
Marketer / Manufacturer Details
MANKIND PHARMA LIMITED
Country of Origin -
India
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